Page last updated: 2024-11-02

oxybutynin and Peripheral Nerve Diseases

oxybutynin has been researched along with Peripheral Nerve Diseases in 10 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Research Excerpts

ExcerptRelevanceReference
"To assess efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in patients with peripheral neuropathic pain."9.15Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain. ( Lu, B; Murphy, FT; Peppin, JF; Tobias, JK; Vanhove, GF; Webster, LR, 2011)
"Neuropathic pain is defined as a direct consequence of an injury or disease that affects the somatosensory system, which may affect 7 to 10% of the world population."5.56Peripheral Neuropathy Associated with Hypereosinophilic Syndrome: A Clinical Therapeutic Success with Capsaicin 8% Patch. ( Gestosa, SVS; Lares, AMG; Mulenas, NME; Ruivo, EFM, 2020)
"To assess efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in patients with peripheral neuropathic pain."5.15Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain. ( Lu, B; Murphy, FT; Peppin, JF; Tobias, JK; Vanhove, GF; Webster, LR, 2011)
"Analgesic treatment of peripheral neuropathic pain with the capsaicin 8% cutaneous patch is safe and effective."2.78Prospective, non-interventional study on the tolerability and analgesic effectiveness over 12 weeks after a single application of capsaicin 8% cutaneous patch in 1044 patients with peripheral neuropathic pain: first results of the QUEPP study. ( Heskamp, ML; Maihofner, C, 2013)
"Neuropathic pain is defined as a direct consequence of an injury or disease that affects the somatosensory system, which may affect 7 to 10% of the world population."1.56Peripheral Neuropathy Associated with Hypereosinophilic Syndrome: A Clinical Therapeutic Success with Capsaicin 8% Patch. ( Gestosa, SVS; Lares, AMG; Mulenas, NME; Ruivo, EFM, 2020)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Ruivo, EFM1
Gestosa, SVS1
Mulenas, NME1
Lares, AMG1
Cabezón-Gutiérrez, L1
Custodio-Cabello, S1
Palka-Kotlowska, M1
Khosravi-Shahi, P1
Sibiya, N1
Mabandla, M1
Simpson, DM1
Brown, S1
Tobias, JK2
Vanhove, GF2
Maihofner, C1
Heskamp, ML1
Kochhar, JS1
Lim, WX1
Zou, S1
Foo, WY1
Pan, J1
Kang, L1
Giménez-Milà, M1
Videla, S1
Navarro, MA1
Faulí, A1
Ojeda, A1
Bogdanovich, A1
Moreno, LA1
Hernández-Cera, C1
Busquets, C1
Misery, L1
Erfan, N1
Castela, E1
Brenaut, E1
Lantéri-Minet, M1
Lacour, JP1
Passeron, T1
Burness, CB1
McCormack, PL1
Webster, LR1
Peppin, JF1
Murphy, FT1
Lu, B1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Controlled Dose Finding Study of NGX-4010 for the Treatment of Painful HIV-Associated Distal Symmetrical Polyneuropathy[NCT00064623]Phase 3300 participants Interventional2003-08-31Completed
Safety and Feasibility of High-Dose Topical Capsaicin for the Treatment of Neuropathic Pain in Pediatric Sickle Cell Disease[NCT03899246]Phase 110 participants (Actual)Interventional2019-07-03Completed
A Randomized, Open-Label Study of the Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain[NCT00082316]Phase 20 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for oxybutynin and Peripheral Nerve Diseases

ArticleYear
High-Dose 8% Capsaicin Patch in Treatment of Chemotherapy-Induced Peripheral Neuropathy. A Systematic Review.
    Journal of pain and symptom management, 2020, Volume: 60, Issue:5

    Topics: Antineoplastic Agents; Capsaicin; Humans; Peripheral Nervous System Diseases; Prospective Studies; R

2020
Capsaicin 8 % Patch: A Review in Peripheral Neuropathic Pain.
    Drugs, 2016, Volume: 76, Issue:1

    Topics: Capsaicin; Diabetic Neuropathies; Humans; Neuralgia, Postherpetic; Pain Management; Peripheral Nervo

2016

Trials

3 trials available for oxybutynin and Peripheral Nerve Diseases

ArticleYear
NGX-4010, a capsaicin 8% dermal patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: results of a 52-week open-label study.
    The Clinical journal of pain, 2014, Volume: 30, Issue:2

    Topics: Adult; Capsaicin; Double-Blind Method; Endpoint Determination; Female; HIV Infections; Humans; Kapla

2014
Prospective, non-interventional study on the tolerability and analgesic effectiveness over 12 weeks after a single application of capsaicin 8% cutaneous patch in 1044 patients with peripheral neuropathic pain: first results of the QUEPP study.
    Current medical research and opinion, 2013, Volume: 29, Issue:6

    Topics: Administration, Cutaneous; Analgesics; Capsaicin; Female; Humans; Male; Middle Aged; Neuralgia; Pain

2013
Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain.
    Diabetes research and clinical practice, 2011, Volume: 93, Issue:2

    Topics: Aged; Anesthetics, Local; Capsaicin; Diabetic Neuropathies; Drug-Related Side Effects and Adverse Re

2011

Other Studies

5 other studies available for oxybutynin and Peripheral Nerve Diseases

ArticleYear
Peripheral Neuropathy Associated with Hypereosinophilic Syndrome: A Clinical Therapeutic Success with Capsaicin 8% Patch.
    Journal of pain & palliative care pharmacotherapy, 2020, Volume: 34, Issue:3

    Topics: Capsaicin; Humans; Hypereosinophilic Syndrome; Male; Middle Aged; Neuralgia; Pain Management; Periph

2020
The pectin-insulin patch application prevents the onset of peripheral neuropathy-like symptoms in streptozotocin-induced diabetic rats.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Hand Strength

2018
Microneedle integrated transdermal patch for fast onset and sustained delivery of lidocaine.
    Molecular pharmaceutics, 2013, Nov-04, Volume: 10, Issue:11

    Topics: Administration, Cutaneous; Adult; Animals; Female; Humans; Lidocaine; Male; Peripheral Nervous Syste

2013
Assessment of the feasibility of high-concentration capsaicin patches in the pain unit of a tertiary hospital for a population of mixed refractory peripheral neuropathic pain syndromes in non-diabetic patients.
    BMC anesthesiology, 2014, Volume: 14

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics; Capsaicin; Feasibility Studie

2014
Successful treatment of refractory neuropathic pruritus with capsaicin 8% patch: a bicentric retrospective study with long-term follow-up.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antipruritics; Capsaicin; Female; France; Humans

2015