Page last updated: 2024-11-02

oxybutynin and Neuralgia, Postherpetic

oxybutynin has been researched along with Neuralgia, Postherpetic in 24 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Neuralgia, Postherpetic: Pain in nerves, frequently involving facial SKIN, resulting from the activation the latent varicella-zoster virus (HERPESVIRUS 3, HUMAN). The two forms of the condition preceding the pain are HERPES ZOSTER OTICUS; and HERPES ZOSTER OPHTHALMICUS. Following the healing of the rashes and blisters, the pain sometimes persists.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy, systemic exposure, safety and tolerability of a transdermal oxycodone patch containing tocopheryl phosphate mixture (TPM) in patients with postherpetic neuralgia (PHN)."9.24Transdermal oxycodone patch for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled trial. ( Brooker, C; Gavin, PD; Smith, A; Tremper, L; Williams, G, 2017)
"Qutenza is a high-dose capsaicin patch used to relieve neuropathic pain from postherpetic neuralgia (PHN) and HIV-associated neuropathy (HIV-AN)."9.20Predictors of Response in Patients With Postherpetic Neuralgia and HIV-Associated Neuropathy Treated With the 8% Capsaicin Patch (Qutenza). ( Katz, NP; Mou, J; Paillard, FC; Stoker, M; Trudeau, J; Turnbull, B, 2015)
"To confirm the efficacy, tolerability, and safety of NGX-4010, an 8% capsaicin dermal patch (capsaicin 640 µg/cm(2) ), in patients with postherpetic neuralgia (PHN)."9.15A multicenter, randomized, double-blind, controlled study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia. ( Backonja, MM; Blonsky, ER; Dunteman, E; Irving, GA; Lu, SP; Tobias, J; Vanhove, GF, 2011)
"To assess efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in patients with peripheral neuropathic pain."9.15Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain. ( Lu, B; Murphy, FT; Peppin, JF; Tobias, JK; Vanhove, GF; Webster, LR, 2011)
"Qutenza (capsaicin) 8% patch is used to treat various neuropathic indications, including postherpetic neuralgia (PHN) and human immunodeficiency virus-associated neuropathy (HIV-AN)."8.90Qutenza (capsaicin) 8% patch onset and duration of response and effects of multiple treatments in neuropathic pain patients. ( Katz, NP; Mou, J; Paillard, F; Stoker, M; Trudeau, J; Turnbull, B, 2014)
"The purpose of this study was to compare the cost effectiveness of a new 8% capsaicin patch, compared to the current treatments for postherpetic neuralgia (PHN), including tricyclic antidepressants (TCAs), topical lidocaine patches, duloxetine, gabapentin, and pregabalin."8.87Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia. ( Armstrong, EP; Malone, DC; McCarberg, B; Panarites, CJ; Pham, SV, 2011)
"To compare healthcare resource utilization and costs of postherpetic neuralgia (PHN) patients initiating lidocaine patch 5% (lidocaine patch) or oral gabapentin/pregabalin."7.76Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin. ( Ben-Joseph, RH; Birnbaum, HG; Ivanova, JI; Kantor, E; Kirson, NY; Puenpatom, RA; Summers, KH; Wei, R, 2010)
"To compare demographic and comorbidity profiles and healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% (lidocaine patch) versus patients not treated with the lidocaine patch."7.76Descriptive analysis of Medicaid patients with postherpetic neuralgia treated with lidocaine patch 5%. ( Amy Puenpatom, R; Ben-Joseph, RH; Birnbaum, HG; Ivanova, JI; Kantor, E; Kirson, NY; Summers, KH; Wei, R, 2010)
"Treatment of chronic pain conditions is commonly assessed at specific endpoints at preset times during or after treatment by analysis of the total study population."6.78A novel approach to identify responder subgroups and predictors of response to low- and high-dose capsaicin patches in postherpetic neuralgia. ( Dahan, A; Krebs-Brown, A; Martini, CH; Olofsen, E; Passier, P; Stoker, M; Yassen, A, 2013)
"Despite currently available treatments, postherpetic neuralgia continues to be a challenging pain condition to treat."6.47Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia. ( Pappagallo, M; Wallace, M, 2011)
"To evaluate the efficacy, systemic exposure, safety and tolerability of a transdermal oxycodone patch containing tocopheryl phosphate mixture (TPM) in patients with postherpetic neuralgia (PHN)."5.24Transdermal oxycodone patch for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled trial. ( Brooker, C; Gavin, PD; Smith, A; Tremper, L; Williams, G, 2017)
"Qutenza is a high-dose capsaicin patch used to relieve neuropathic pain from postherpetic neuralgia (PHN) and HIV-associated neuropathy (HIV-AN)."5.20Predictors of Response in Patients With Postherpetic Neuralgia and HIV-Associated Neuropathy Treated With the 8% Capsaicin Patch (Qutenza). ( Katz, NP; Mou, J; Paillard, FC; Stoker, M; Trudeau, J; Turnbull, B, 2015)
"To confirm the efficacy, tolerability, and safety of NGX-4010, an 8% capsaicin dermal patch (capsaicin 640 µg/cm(2) ), in patients with postherpetic neuralgia (PHN)."5.15A multicenter, randomized, double-blind, controlled study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia. ( Backonja, MM; Blonsky, ER; Dunteman, E; Irving, GA; Lu, SP; Tobias, J; Vanhove, GF, 2011)
"To assess efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in patients with peripheral neuropathic pain."5.15Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain. ( Lu, B; Murphy, FT; Peppin, JF; Tobias, JK; Vanhove, GF; Webster, LR, 2011)
" A high-concentration capsaicin 179-mg cutaneous patch (Qutenza™) is licensed in adults for chronic neuropathic pain in the EU, and neuropathic pain with post-herpetic neuralgia and neuropathic pain with diabetic peripheral neuropathy in the USA."5.12Capsaicin 179-mg cutaneous patch in the treatment of post-surgical neuropathic pain: a scoping review of current evidence and place in therapy. ( Casale, R, 2021)
"Qutenza (capsaicin) 8% patch is used to treat various neuropathic indications, including postherpetic neuralgia (PHN) and human immunodeficiency virus-associated neuropathy (HIV-AN)."4.90Qutenza (capsaicin) 8% patch onset and duration of response and effects of multiple treatments in neuropathic pain patients. ( Katz, NP; Mou, J; Paillard, F; Stoker, M; Trudeau, J; Turnbull, B, 2014)
"The purpose of this study was to compare the cost effectiveness of a new 8% capsaicin patch, compared to the current treatments for postherpetic neuralgia (PHN), including tricyclic antidepressants (TCAs), topical lidocaine patches, duloxetine, gabapentin, and pregabalin."4.87Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia. ( Armstrong, EP; Malone, DC; McCarberg, B; Panarites, CJ; Pham, SV, 2011)
"Overall, 68 patients with PNP conditions, including facial neuropathy (severe trigeminal neuralgia in V2), polyneuropathy, post-herpetic neuralgia, and mononeuropathies, received 96 treatments with the capsaicin 8% patch."3.79The capsaicin 8% patch for neuropathic pain in clinical practice: a retrospective analysis. ( Poole, C; Roth-Daniek, A; Wagner, T, 2013)
"Qutenza is a high-potency capsaicin (8%) topical patch, labeled for treating pain associated with postherpetic neuralgia (PHN)."3.77Capsaicin 8% topical patch (Qutenza)--a review of the evidence. ( Jones, VM; Moore, KA; Peterson, DM, 2011)
"To compare healthcare resource utilization and costs of postherpetic neuralgia (PHN) patients initiating lidocaine patch 5% (lidocaine patch) or oral gabapentin/pregabalin."3.76Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin. ( Ben-Joseph, RH; Birnbaum, HG; Ivanova, JI; Kantor, E; Kirson, NY; Puenpatom, RA; Summers, KH; Wei, R, 2010)
"To compare demographic and comorbidity profiles and healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% (lidocaine patch) versus patients not treated with the lidocaine patch."3.76Descriptive analysis of Medicaid patients with postherpetic neuralgia treated with lidocaine patch 5%. ( Amy Puenpatom, R; Ben-Joseph, RH; Birnbaum, HG; Ivanova, JI; Kantor, E; Kirson, NY; Summers, KH; Wei, R, 2010)
"Treatment of chronic pain conditions is commonly assessed at specific endpoints at preset times during or after treatment by analysis of the total study population."2.78A novel approach to identify responder subgroups and predictors of response to low- and high-dose capsaicin patches in postherpetic neuralgia. ( Dahan, A; Krebs-Brown, A; Martini, CH; Olofsen, E; Passier, P; Stoker, M; Yassen, A, 2013)
"Despite currently available treatments, postherpetic neuralgia continues to be a challenging pain condition to treat."2.47Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia. ( Pappagallo, M; Wallace, M, 2011)
"Several guidelines for neuropathic pain management and various effective drugs are available; however, neuropathic pain remains undertreated."1.48Efficacy Analysis of Capsaicin 8% Patch in Neuropathic Peripheral Pain Treatment. ( Fernandes, HL; Gama, R; Loureiro, MC; Pereira, FC; Tenreiro Pinto, J, 2018)
"Localized neuropathic pain (LNP) is a subgroup of neuropathic pain characterized by consistent and circumscribed area(s) of maximum pain, associated with negative or positive sensory signs and/or spontaneous symptoms characteristic of NP."1.48Efficacy of lidocaine 5% medicated plaster (VERSATIS®) in patients with localized neuropathic pain poorly responsive to pharmacological therapy. ( Chinellato, E; Del Balzo, G; Martini, A; Parolini, M; Picelli, A; Polati, E; Schweiger, V; Tamburin, S; Zanzotti, M, 2018)
"Additionally, gabapentin was given for neuropathic pain uncontrolled by opioids."1.37[Oxycodone and pregabalin using transdermal fentanyl patch provided relief of symptoms for postherpetic neuropathic pain in a patient with non-small cell lung cancer]. ( Ando, A; Nishimura, D; Shibahara, H; Suzuki, S; Uematsu, N, 2011)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's22 (91.67)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Casale, R1
Shaparin, N1
Nair, S1
Vydyanathan, A1
Hascalovici, JR1
Gavin, PD1
Tremper, L1
Smith, A1
Williams, G1
Brooker, C1
Tenreiro Pinto, J1
Pereira, FC1
Loureiro, MC1
Gama, R1
Fernandes, HL1
Martini, A1
Del Balzo, G1
Schweiger, V1
Zanzotti, M1
Picelli, A1
Parolini, M1
Chinellato, E1
Tamburin, S1
Polati, E1
Blair, HA1
Martini, CH1
Yassen, A1
Krebs-Brown, A1
Passier, P1
Stoker, M3
Olofsen, E1
Dahan, A1
Wagner, T1
Poole, C1
Roth-Daniek, A1
Mou, J2
Paillard, F1
Turnbull, B2
Trudeau, J2
Katz, NP2
Paillard, FC1
Burness, CB1
McCormack, PL1
Riopelle, J1
Kaye, AD1
Andersen, HH1
Sand, C1
Elberling, J1
Kirson, NY2
Ivanova, JI2
Birnbaum, HG2
Wei, R2
Kantor, E2
Puenpatom, RA1
Ben-Joseph, RH2
Summers, KH2
Amy Puenpatom, R1
Webster, LR2
Tark, M1
Rauck, R1
Tobias, JK2
Vanhove, GF3
Irving, GA1
Backonja, MM1
Dunteman, E1
Blonsky, ER1
Lu, SP1
Tobias, J1
Wallace, M1
Pappagallo, M1
Armstrong, EP1
Malone, DC1
McCarberg, B1
Panarites, CJ1
Pham, SV1
Jones, VM1
Moore, KA1
Peterson, DM1
Peppin, JF1
Murphy, FT1
Lu, B1
Argoff, CE1
Shibahara, H1
Ando, A1
Suzuki, S1
Uematsu, N1
Nishimura, D1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Feasibility of High-Dose Topical Capsaicin for the Treatment of Neuropathic Pain in Pediatric Sickle Cell Disease[NCT03899246]Phase 110 participants (Actual)Interventional2019-07-03Completed
A Randomized, Double-Blind, Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia[NCT00068081]Phase 3150 participants InterventionalCompleted
A Multicenter Randomized, Double-Blind, Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia[NCT00300222]Phase 3400 participants Interventional2006-03-31Completed
A Randomized, Open-Label Study of the Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain[NCT00082316]Phase 20 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for oxybutynin and Neuralgia, Postherpetic

ArticleYear
Capsaicin 179-mg cutaneous patch in the treatment of post-surgical neuropathic pain: a scoping review of current evidence and place in therapy.
    Expert review of neurotherapeutics, 2021, Volume: 21, Issue:10

    Topics: Adult; Capsaicin; Diabetic Neuropathies; Humans; Neuralgia; Neuralgia, Postherpetic; Pain, Postopera

2021
Capsaicin 8% Dermal Patch: A Review in Peripheral Neuropathic Pain.
    Drugs, 2018, Volume: 78, Issue:14

    Topics: Administration, Cutaneous; Analgesics; Capsaicin; HIV Infections; Humans; Neuralgia; Neuralgia, Post

2018
ZTlido--a new lidocaine patch for postherpetic neuralgia.
    The Medical letter on drugs and therapeutics, 2019, Mar-25, Volume: 61, Issue:1568

    Topics: Anesthetics, Local; Animals; Humans; Lidocaine; Neuralgia, Postherpetic; Transdermal Patch

2019
Qutenza (capsaicin) 8% patch onset and duration of response and effects of multiple treatments in neuropathic pain patients.
    The Clinical journal of pain, 2014, Volume: 30, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Capsaicin; Databases, Factual; Dose-Response Relationship, Drug; Dou

2014
Capsaicin 8 % Patch: A Review in Peripheral Neuropathic Pain.
    Drugs, 2016, Volume: 76, Issue:1

    Topics: Capsaicin; Diabetic Neuropathies; Humans; Neuralgia, Postherpetic; Pain Management; Peripheral Nervo

2016
Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia.
    Expert review of neurotherapeutics, 2011, Volume: 11, Issue:1

    Topics: Administration, Cutaneous; Capsaicin; Clinical Trials as Topic; Europe; Humans; Neuralgia, Postherpe

2011
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia.
    Current medical research and opinion, 2011, Volume: 27, Issue:5

    Topics: Administration, Topical; Amines; Anesthetics, Local; Antidepressive Agents, Tricyclic; Capsaicin; Cl

2011
Review of current guidelines on the care of postherpetic neuralgia.
    Postgraduate medicine, 2011, Volume: 123, Issue:5

    Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanecarb

2011

Trials

6 trials available for oxybutynin and Neuralgia, Postherpetic

ArticleYear
Transdermal oxycodone patch for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled trial.
    Pain management, 2017, Volume: 7, Issue:4

    Topics: Adult; alpha-Tocopherol; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Drug Combinati

2017
A novel approach to identify responder subgroups and predictors of response to low- and high-dose capsaicin patches in postherpetic neuralgia.
    European journal of pain (London, England), 2013, Volume: 17, Issue:10

    Topics: Aged; Aged, 80 and over; Capsaicin; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Ma

2013
Predictors of Response in Patients With Postherpetic Neuralgia and HIV-Associated Neuropathy Treated With the 8% Capsaicin Patch (Qutenza).
    The Clinical journal of pain, 2015, Volume: 31, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; AIDS-Associated Nephropathy; Analysis of Variance; Capsaicin; Dose-R

2015
Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia.
    BMC neurology, 2010, Oct-11, Volume: 10

    Topics: Aged; Capsaicin; Double-Blind Method; Female; Humans; Male; Neuralgia, Postherpetic; Pain Measuremen

2010
A multicenter, randomized, double-blind, controlled study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia.
    Pain medicine (Malden, Mass.), 2011, Volume: 12, Issue:1

    Topics: Administration, Topical; Aged; Analgesics; Capsaicin; Dose-Response Relationship, Drug; Double-Blind

2011
Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain.
    Diabetes research and clinical practice, 2011, Volume: 93, Issue:2

    Topics: Aged; Anesthetics, Local; Capsaicin; Diabetic Neuropathies; Drug-Related Side Effects and Adverse Re

2011

Other Studies

10 other studies available for oxybutynin and Neuralgia, Postherpetic

ArticleYear
Expanding frontiers in telehealth: Video assisted at-home application of capsaicin 8% patch.
    European journal of pain (London, England), 2021, Volume: 25, Issue:7

    Topics: Capsaicin; Female; Humans; Neuralgia, Postherpetic; Pain Measurement; Sensory System Agents; Telemed

2021
Efficacy Analysis of Capsaicin 8% Patch in Neuropathic Peripheral Pain Treatment.
    Pharmacology, 2018, Volume: 101, Issue:5-6

    Topics: Administration, Cutaneous; Aged; Capsaicin; Female; Humans; Male; Middle Aged; Neuralgia; Neuralgia,

2018
Efficacy of lidocaine 5% medicated plaster (VERSATIS®) in patients with localized neuropathic pain poorly responsive to pharmacological therapy.
    Minerva medica, 2018, Volume: 109, Issue:5

    Topics: Aged; Analgesics; Anesthetics, Local; Drug Evaluation; Drug Resistance; Drug Therapy, Combination; E

2018
The capsaicin 8% patch for neuropathic pain in clinical practice: a retrospective analysis.
    Pain medicine (Malden, Mass.), 2013, Volume: 14, Issue:8

    Topics: Capsaicin; Failed Back Surgery Syndrome; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neura

2013
Transition from Injectable to Percutaneous Local Anesthetic Therapy in a Patient with Post-Herpetic Neuralgia.
    Pain physician, 2016, Volume: 19, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Female; Humans; Injections, Subcutaneous; Neuralgia, Po

2016
[Effective pain relief of post-herpetic neuralgia with capsaicin patch].
    Ugeskrift for laeger, 2016, Feb-01, Volume: 178, Issue:5

    Topics: Capsaicin; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Sensory System Agen

2016
Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin.
    Journal of medical economics, 2010, Volume: 13, Issue:3

    Topics: Amines; Analgesics; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-

2010
Descriptive analysis of Medicaid patients with postherpetic neuralgia treated with lidocaine patch 5%.
    Journal of medical economics, 2010, Volume: 13, Issue:3

    Topics: Aged; Analysis of Variance; Anesthetics, Local; Comorbidity; Female; Health Care Costs; Humans; Insu

2010
Capsaicin 8% topical patch (Qutenza)--a review of the evidence.
    Journal of pain & palliative care pharmacotherapy, 2011, Volume: 25, Issue:1

    Topics: Administration, Cutaneous; Capsaicin; Clinical Trials as Topic; Humans; Neuralgia, Postherpetic; Pai

2011
[Oxycodone and pregabalin using transdermal fentanyl patch provided relief of symptoms for postherpetic neuropathic pain in a patient with non-small cell lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:10

    Topics: Aged; Analgesics, Opioid; Carcinoma, Non-Small-Cell Lung; Fentanyl; gamma-Aminobutyric Acid; Humans;

2011