oxybutynin has been researched along with Depressive Disorder in 5 studies
oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients received stepwise pain treatment in which those who did not use analgesics were randomized to receive either paracetamol (3 g/day) or placebo tablets; those who already used pain treatment were allocated to buprenorphine transdermal system (max." | 5.27 | Effects of pain treatment on sleep in nursing home patients with dementia and depression: A multicenter placebo-controlled randomized clinical trial. ( Bjorvatn, B; Blytt, KM; Flo, E; Husebo, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shader, RI | 1 |
| Oesterheld, JR | 1 |
| Blytt, KM | 1 |
| Bjorvatn, B | 1 |
| Husebo, B | 1 |
| Flo, E | 1 |
| Schmidt, PJ | 1 |
| Ben Dor, R | 1 |
| Martinez, PE | 1 |
| Guerrieri, GM | 1 |
| Harsh, VL | 1 |
| Thompson, K | 1 |
| Koziol, DE | 1 |
| Nieman, LK | 1 |
| Rubinow, DR | 1 |
| Barkin, RL | 1 |
| Barkin, SJ | 1 |
| Irving, GA | 1 |
| Gordon, A | 1 |
| Rastogi, R | 1 |
| Swarm, RA | 1 |
| Patel, TA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis[NCT05282277] | Phase 4 | 103 participants (Anticipated) | Interventional | 2022-04-20 | Recruiting | ||
| The Effects of Acute Withdrawal of Estradiol on Mood Symptoms in Women With Perimenopausal Depression[NCT00060736] | 60 participants (Actual) | Observational | 2003-05-05 | Completed | |||
| Effects of a Tissue Selective Estrogen Complex (TESC) on Depression and the Neural Reward System in the Perimenopause[NCT03740009] | Phase 4 | 20 participants (Actual) | Interventional | 2019-01-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The primary outcome measure is functional magnetic resonance imaging (fMRI) data collected during a Monetary Incentive Delay (MID) Task. All participants will complete the fMRI Monetary Incentive Delay (MID) task at baseline and at 3 weeks. During the task, participants need to select the correct response during win and lose conditions by pressing a button on a button box in the MRI. Participant's blood-oxygen-level dependent (BOLD) activation response (A measurement of oxygen level that is released to neurons since areas of the brain that are thought to be more active or involved in certain tasks require more oxygen to perform the tasks.) is measured while they performed the task in MRI scanner." (NCT03740009)
Timeframe: Baseline to 3 weeks
| Intervention | percent signal change (Mean) | |||||
|---|---|---|---|---|---|---|
| Caudate Baseline | Caudate Posttreatment | Nucleus Accumbens Baseline | Nucleus Accumbens Posttreatment | Putamen Baseline | Putamen Posttreatment | |
| Perimenopausal Women, Depressed | .0704 | .0475 | .0623 | .0280 | .0399 | .0408 |
The second primary outcome measure uses the Mood and Anxiety Symptoms Questionnaire - Anhedonic Depression Scale (MASQ-AD) to examine symptom change. All participants will complete the MASQ-AD at each study visit, which measures their current symptoms of depression and anxiety. Scores range from 22 to 110 with lower scores reflecting a better outcome. (NCT03740009)
Timeframe: Baseline, week 2, week 3, week 4 (post treatment)
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Baseline Week 1 | Week 2 | Week 3 | Post Treatment Week 4 | |
| Perimenopausal Women, Depressed | 72.1 | 62.4 | 57.2 | 54.5 |
2 reviews available for oxybutynin and Depressive Disorder
| Article | Year |
|---|---|
Management of chronic noncancer pain in depressed patients.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2011 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhi | 2011 |
2 trials available for oxybutynin and Depressive Disorder
| Article | Year |
|---|---|
Effects of pain treatment on sleep in nursing home patients with dementia and depression: A multicenter placebo-controlled randomized clinical trial.
Topics: Acetaminophen; Adult; Aged; Analgesics; Buprenorphine; Dementia; Depressive Disorder; Double-Blind M | 2018 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.
Topics: Aged; Cross-Over Studies; Depression; Depressive Disorder; Double-Blind Method; Estradiol; Estrogen | 2015 |
1 other study available for oxybutynin and Depressive Disorder
| Article | Year |
|---|---|
Case 7: the addled nonagenarian.
Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Confusion; Depressive Diso | 1995 |