oxybutynin has been researched along with Cognition Disorders in 16 studies
oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Participants (N = 365) in a larger smoking cessation clinical trial completed the modified Simon task twice (while 10-h nicotine-deprived vs." | 5.15 | Cognitive conflict following appetitive versus negative cues and smoking cessation failure. ( Baker, TB; Curtin, JJ; Gloria, R; Japuntich, SJ; Piper, ME; Schlam, TR, 2011) |
| "Fifty women aged 65 and older with urge incontinence and cognitive impairment." | 2.76 | Efficacy of oral extended-release oxybutynin in cognitively impaired older nursing home residents with urge urinary incontinence: a randomized placebo-controlled trial. ( Davey, C; Lackner, TE; McCarthy, TC; Monigold, M; Wyman, JF, 2011) |
| "Oxybutynin was associated with statistically significant impairments in several measures of cognitive function at a time point corresponding with its probable C(max)." | 2.74 | Exploratory pilot study assessing the risk of cognitive impairment or sedation in the elderly following single doses of solifenacin 10 mg. ( Bolodeoku, J; Edgar, C; Tretter, RN; Wesnes, KA, 2009) |
| "Oxybutynin was shown to have largest effect towards the decline of MMSE score [Mean difference: -2." | 2.66 | Effect of Antimuscarinic Drugs on Cognitive Functions in the Management of Overactive Bladder in Elderly. ( Rahardjo, HE; Rangganata, E; Widia, F, 2020) |
| "Incidences of overactive bladder (OAB) and cognitive dysfunction increase with aging." | 1.42 | Influence of antimuscarinic therapy on cognitive functions and quality of life in geriatric patients treated for overactive bladder. ( Ariogul, S; Cankurtaran, E; Cankurtaran, M; Ergen, A; Esin, E; Halil, M; Kuyumcu, ME; Ozcan, M; Ulger, Z; Yavuz, BB; Yeşil, Y, 2015) |
| "The study comprised 225 children with a neurogenic bladder from MMC who were evaluated with urodynamic testing and voiding cysto-urethrography to identify those at high risk of upper tract damage." | 1.31 | Side-effects of oral or intravesical oxybutynin chloride in children with spina bifida. ( D'Aleo, CM; Ferrara, P; Salvaggio, E; Salvatore, S; Tarquini, E, 2001) |
| " More rigid dosage schedules with longer time intervals between doses are needed." | 1.28 | [Overdose of anticholinergic agents and confusional syndrome]. ( Choulot, JJ; Mensire, A; Saint Martin, J, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Rangganata, E | 1 |
| Widia, F | 1 |
| Rahardjo, HE | 1 |
| Esin, E | 1 |
| Ergen, A | 1 |
| Cankurtaran, M | 1 |
| Yavuz, BB | 1 |
| Halil, M | 1 |
| Ulger, Z | 1 |
| Yeşil, Y | 1 |
| Kuyumcu, ME | 1 |
| Ozcan, M | 1 |
| Cankurtaran, E | 1 |
| Ariogul, S | 1 |
| Harari, D | 1 |
| Igbedioh, C | 1 |
| Wesnes, KA | 1 |
| Edgar, C | 1 |
| Tretter, RN | 1 |
| Bolodeoku, J | 1 |
| Jakobsen, SM | 1 |
| Kersten, H | 1 |
| Molden, E | 1 |
| Lackner, TE | 1 |
| Wyman, JF | 1 |
| McCarthy, TC | 1 |
| Monigold, M | 1 |
| Davey, C | 1 |
| Sink, KM | 1 |
| Thomas, J | 1 |
| Xu, H | 1 |
| Craig, B | 1 |
| Kritchevsky, S | 1 |
| Sands, LP | 2 |
| Donnellan, CA | 1 |
| Fook, L | 1 |
| McDonald, P | 1 |
| Playfer, JR | 1 |
| Katz, IR | 1 |
| Bilker, W | 1 |
| DiFilippo, S | 1 |
| Boyce, A | 1 |
| D'Angelo, K | 1 |
| Ferrara, P | 1 |
| D'Aleo, CM | 1 |
| Tarquini, E | 1 |
| Salvatore, S | 1 |
| Salvaggio, E | 1 |
| Oka, T | 1 |
| Nakano, K | 1 |
| Kirimoto, T | 1 |
| Matsuura, N | 1 |
| Choulot, JJ | 1 |
| Mensire, A | 1 |
| Saint Martin, J | 1 |
| Kulkarni, J | 1 |
| Gavrilidis, E | 1 |
| Wang, W | 1 |
| Worsley, R | 1 |
| Fitzgerald, PB | 1 |
| Gurvich, C | 1 |
| Van Rheenen, T | 1 |
| Berk, M | 1 |
| Burger, H | 1 |
| Isaacson, RS | 1 |
| Ferris, S | 1 |
| Velting, DM | 1 |
| Meng, X | 1 |
| Zhang, ZX | 1 |
| Hong, Z | 1 |
| Wang, YP | 1 |
| He, L | 1 |
| Wang, N | 1 |
| Zhao, ZX | 1 |
| Zhao, G | 1 |
| Shang, L | 1 |
| Weisskopf, M | 1 |
| Callegari, F | 1 |
| Strohmaier, C | 1 |
| Schlam, TR | 1 |
| Japuntich, SJ | 1 |
| Piper, ME | 1 |
| Gloria, R | 1 |
| Baker, TB | 1 |
| Curtin, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double Blind, Randomized Four Way Cross Over Study to Compare the Effect of Fesoterodine 4mg and 8mg Once Daily and Oxybutynin 5mg Twice Daily After Steady State Dosing Versus Placebo on Cognitive Function in Subjects With Overactive Bladder, Over the A[NCT02240459] | Phase 2 | 47 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Randomized Cross-Over Study of Fesoterodine on Urgency Episodes in Parkinson's Disease Population[NCT02385500] | Phase 4 | 5 participants (Actual) | Interventional | 2016-09-30 | Terminated (stopped due to Insufficient or untimely patient recruitment) | ||
| Peppermint Oil as an Alternative Treatment for Children With Bladder and Bowel Dysfunction: A Prospective Study[NCT05613153] | 30 participants (Anticipated) | Interventional | 2022-11-01 | Enrolling by invitation | |||
| Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis[NCT05282277] | Phase 4 | 103 participants (Anticipated) | Interventional | 2022-04-20 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for oxybutynin and Cognition Disorders
| Article | Year |
|---|---|
Effect of Antimuscarinic Drugs on Cognitive Functions in the Management of Overactive Bladder in Elderly.
Topics: Aged; Benzofurans; Cognition Disorders; Humans; Mandelic Acids; Mental Status and Dementia Tests; Mu | 2020 |
7 trials available for oxybutynin and Cognition Disorders
| Article | Year |
|---|---|
Exploratory pilot study assessing the risk of cognitive impairment or sedation in the elderly following single doses of solifenacin 10 mg.
Topics: Aged; Attention; Cognition; Cognition Disorders; Cross-Over Studies; Executive Function; Female; Hum | 2009 |
Efficacy of oral extended-release oxybutynin in cognitively impaired older nursing home residents with urge urinary incontinence: a randomized placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Cholinergic Antagonists; Cognition Disorders; Delayed-Action Preparations; | 2011 |
Identification of medications that cause cognitive impairment in older people: the case of oxybutynin chloride.
Topics: Aged; Analysis of Variance; Cholinergic Antagonists; Cognition Disorders; Cross-Over Studies; Diphen | 1998 |
Estradiol for treatment-resistant schizophrenia: a large-scale randomized-controlled trial in women of child-bearing age.
Topics: Adolescent; Adult; Cognition Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Estra | 2015 |
Cognitive Efficacy (SIB) of 13.3 Versus 4.6 mg/24 h Rivastigmine Patch in Severe Alzheimer's Disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; C | 2016 |
Rivastigmine Patch in Chinese Patients with Probable Alzheimer's disease: A 24-week, Randomized, Double-Blind Parallel-Group Study Comparing Rivastigmine Patch (9.5 mg/24 h) with Capsule (6 mg Twice Daily).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Asian People; Cognition Disorders; Double-Blind Method; | 2016 |
Cognitive conflict following appetitive versus negative cues and smoking cessation failure.
Topics: Adult; Appetitive Behavior; Cognition Disorders; Conflict, Psychological; Cues; Dose-Response Relati | 2011 |
8 other studies available for oxybutynin and Cognition Disorders
| Article | Year |
|---|---|
Influence of antimuscarinic therapy on cognitive functions and quality of life in geriatric patients treated for overactive bladder.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Benzhydryl Compounds; Benzilates; Benzofurans; | 2015 |
Restoring continence in frail older people living in the community: what factors influence successful treatment outcomes?
Topics: Aged; Aged, 80 and over; Cognition Disorders; Comorbidity; Exercise; Female; Follow-Up Studies; Frai | 2009 |
Evaluation of brain anticholinergic activities of urinary spasmolytic drugs using a high-throughput radio receptor bioassay.
Topics: Benzhydryl Compounds; Benzofurans; Biological Assay; Brain; Cognition Disorders; Cresols; Humans; In | 2011 |
Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Benzhydryl Compounds; Cholinergic Antagonists; | 2008 |
Oxybutynin and cognitive dysfunction.
Topics: Aged; Aged, 80 and over; Cholinergic Antagonists; Cognition Disorders; Confusion; Humans; Male; Mand | 1997 |
Oxybutynin and cognitive dysfunction.
Topics: Aged; Aged, 80 and over; Cholinergic Antagonists; Cognition Disorders; Confusion; Humans; Male; Mand | 1997 |
Oxybutynin and cognitive dysfunction.
Topics: Aged; Aged, 80 and over; Cholinergic Antagonists; Cognition Disorders; Confusion; Humans; Male; Mand | 1997 |
Oxybutynin and cognitive dysfunction.
Topics: Aged; Aged, 80 and over; Cholinergic Antagonists; Cognition Disorders; Confusion; Humans; Male; Mand | 1997 |
Side-effects of oral or intravesical oxybutynin chloride in children with spina bifida.
Topics: Administration, Intravesical; Administration, Oral; Child; Child, Preschool; Cholinergic Antagonists | 2001 |
Effects of antimuscarinic drugs on both urinary frequency and cognitive impairment in conscious, nonrestrained rats.
Topics: Administration, Oral; Animals; Basal Nucleus of Meynert; Benzilates; Cognition Disorders; Consciousn | 2001 |
[Overdose of anticholinergic agents and confusional syndrome].
Topics: Child; Cognition Disorders; Confusion; Enuresis; Humans; Male; Mandelic Acids; Parasympatholytics | 1989 |