Page last updated: 2024-11-02

oxybutynin and Cholera Infantum

oxybutynin has been researched along with Cholera Infantum in 2 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Research Excerpts

ExcerptRelevanceReference
"Loxoprofen (LOX) is a nonsteroidal anti-inflammatory drug (NSAID)."6.90Efficacy and Safety of Loxoprofen Hydrogel Transdermal Patch Versus Loxoprofen Tablet in Chinese Patients with Myalgia: A Double-Blind, Double-Dummy, Parallel-Group, Randomized, Controlled, Non-Inferiority Trial. ( Chen, Z; Hu, S; Li, Z; Lin, J; Shao, Z; Shi, Y; Wang, G; Xiao, W; Zhang, Z; Zhao, D; Zheng, Y, 2019)
"Loxoprofen (LOX) is a nonsteroidal anti-inflammatory drug (NSAID)."2.90Efficacy and Safety of Loxoprofen Hydrogel Transdermal Patch Versus Loxoprofen Tablet in Chinese Patients with Myalgia: A Double-Blind, Double-Dummy, Parallel-Group, Randomized, Controlled, Non-Inferiority Trial. ( Chen, Z; Hu, S; Li, Z; Lin, J; Shao, Z; Shi, Y; Wang, G; Xiao, W; Zhang, Z; Zhao, D; Zheng, Y, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, D1
Chen, Z1
Hu, S1
Lin, J1
Shao, Z1
Wang, G1
Xiao, W1
Zheng, Y1
Zhang, Z1
Shi, Y1
Li, Z1
Woitalla, D1
Kassubek, J1
Timmermann, L1
Lauterbach, T1
Berkels, R1
Grieger, F1
Müller, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicentric, Non-interventional Study on Switching From Oral Parkinson Therapy to Neupro® in Patients With Idiopathic Parkinson's Disease With Gastrointestinal Symptoms[NCT01159691]76 participants (Actual)Observational2010-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline to Visit 3 in the Assessment of Intensity of Gastrointestinal (GI) Complaints for Any Reason as Per Visual Analogue Scale (VAS)

Patients were asked to classify the intensity of their GI complaints on a scale ranging from 0 (no complaints) to 100 (extremely severe complaints). Negative values indicate an improvement from Baseline to Visit 3 with larger negative values showing a better improvement. (NCT01159691)
Timeframe: From Baseline to Visit 3 (approximately 6 weeks)

Interventionmillimeter (mm) (Mean)
Neupro-26.8

Change From Baseline to Visit 3 in the Sum Score of Gastrointestinal (GI) Complaints

"Sum score of GI complaints was calculated from frequency and intensity of the complaints. The intensity of GI complaints during the last week ranges from 0 (no complaints) to 3 (severe) and the frequency of these complaints during the last week ranges from 0 (never) to 4 (every day).~For each of the seven GI complaints assessed at a visit (swallowing disorders, heartburn, feeling of fullness, nausea, vomiting, abdominal pain, and diarrhea), intensity and frequency were multiplied to achieve individual item scores of GI complaints (range: 0 - 12).~Finally, the sum score of GI complaints per visit was calculated by accumulating 6 of the 7 item scores (excluding swallowing disorders, which was recorded at Baseline only) for patients with valid values in each score (range: 0 - 72). Negative values indicate an improvement from Baseline to Visit 3 with larger negative values showing a better improvement." (NCT01159691)
Timeframe: From Baseline to Visit 3 (approximately 6 weeks)

Interventionunits on a scale (Mean)
Neupro-8.4

Assessment of Patient Satisfaction Referring to Gastrointestinal (GI) Complaints Following Treatment Switch to Neupro® at Visit 2

"Patient satisfaction referring to GI complaints is classified into 5 categories:~Missing~Very satisfied~Satisfied~Moderately satisfied~Not satisfied." (NCT01159691)
Timeframe: At Visit 2 (after approximately 2-4 weeks)

Interventionparticipants (Number)
MissingVery satisfiedSatisfiedModerately satisfiedNot satisfied
Neupro1252685

Assessment of Patient Satisfaction Referring to Gastrointestinal (GI) Complaints Following Treatment Switch to Neupro® at Visit 3

"Patient satisfaction referring to GI complaints is classified into 5 categories:~Missing~Very satisfied~Satisfied~Moderately satisfied~Not satisfied." (NCT01159691)
Timeframe: At Visit 3 (after approximately 6 weeks)

Interventionparticipants (Number)
MissingVery satisfiedSatisfiedModerately satisfiedNot satisfied
Neupro7282262

Trials

2 trials available for oxybutynin and Cholera Infantum

ArticleYear
Efficacy and Safety of Loxoprofen Hydrogel Transdermal Patch Versus Loxoprofen Tablet in Chinese Patients with Myalgia: A Double-Blind, Double-Dummy, Parallel-Group, Randomized, Controlled, Non-Inferiority Trial.
    Clinical drug investigation, 2019, Volume: 39, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; China; Double-Blind Meth

2019
Reduction of gastrointestinal symptoms in Parkinson's disease after a switch from oral therapy to rotigotine transdermal patch: a non-interventional prospective multicenter trial.
    Parkinsonism & related disorders, 2015, Volume: 21, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antiparkinson Agents; Female; Follow-Up Studies; Gast

2015