Page last updated: 2024-11-02

oxybutynin and Chemical Dependence

oxybutynin has been researched along with Chemical Dependence in 6 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Research Excerpts

ExcerptRelevanceReference
"Fentanyl is a potent synthetic opioid with large abuse potential."1.38Whole fentanyl patch ingestion: a multi-center case series. ( Brooks, DE; Duback-Morris, LF; Feuchter, AC; Katz, KD; Krenzelok, EP; Mrvos, R, 2012)
"Fentanyl is a synthetic opioid available therapeutically as an intravenous, transbucal, or transdermal preparation."1.36Complications of oral exposure to fentanyl transdermal delivery system patches. ( Jones, BE; Nelson, L; Prosser, JM, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mutlu, EA1
Algate, DR1
Beard, DJ1
Davis, MP1
Pasternak, G1
Behm, B1
Prosser, JM1
Jones, BE1
Nelson, L1
Mrvos, R1
Feuchter, AC1
Katz, KD1
Duback-Morris, LF1
Brooks, DE1
Krenzelok, EP1
Reimherr, FW1
Marchant, BK1
Olsen, JL1
Wender, PH1
Robison, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Methylphenidate Transdermal System (MTS) in the Treatment of Adult ADHD[NCT00506285]Phase 392 participants (Actual)Interventional2007-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Conners' Adult ADHD Rating Scales (CAARS)

Measures the DSM based ADHD criteria of Inattention and Hyperactivity/Impulsivity. There are 30 items scored 0-3 for a minimum score of 0 (no symptoms) and a maximum score of 90 worst possible symptoms. (NCT00506285)
Timeframe: Double-blind endpoints for MTS and placebo arms

Interventionunits on a scale (Mean)
Scores in MTS Arm30.8
Scores in Placebo Arm49.5

Wender Reimherr Adult Attention Deficit Disorder Scale

This scale measures the 7 domains of the Utah Criteria for Adult ADHD. Total scores run from 0 to 28. Normative samples average below 5. The worst possible score is 28. (NCT00506285)
Timeframe: Double-blind endpoints during MTS and placebo arms

Interventionunits on a scale (Mean)
Scores in MTS Arm11.0
Scores in Placebo Arm17.9

Reviews

1 review available for oxybutynin and Chemical Dependence

ArticleYear
Treating Chronic Pain: An Overview of Clinical Studies Centered on the Buprenorphine Option.
    Drugs, 2018, Volume: 78, Issue:12

    Topics: Administration, Sublingual; Analgesics, Opioid; Animals; Buprenorphine; Chemistry, Pharmaceutical; C

2018

Trials

1 trial available for oxybutynin and Chemical Dependence

ArticleYear
Oppositional defiant disorder in adults with ADHD.
    Journal of attention disorders, 2013, Volume: 17, Issue:2

    Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperact

2013

Other Studies

4 other studies available for oxybutynin and Chemical Dependence

ArticleYear
Oxybutynin dependence: a case presentation.
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2011,Summer, Volume: 22, Issue:2

    Topics: Adult; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Parasympatholytics; Substance Withdrawa

2011
The physical dependence liabilities of oxybutynin and morphine in rats.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:10

    Topics: Animals; Male; Mandelic Acids; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains;

1985
Complications of oral exposure to fentanyl transdermal delivery system patches.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:4

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Databases, Factual; Female; Fentanyl; Humans; Male;

2010
Whole fentanyl patch ingestion: a multi-center case series.
    The Journal of emergency medicine, 2012, Volume: 42, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Delayed-Action Preparations; Female; Fe

2012