Page last updated: 2024-11-02

oxybutynin and Bradycardia

oxybutynin has been researched along with Bradycardia in 2 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
"This case report describes a patient who developed severe bradycardia due to transdermal fentanyl."7.79Case report of severe bradycardia due to transdermal fentanyl. ( Hawley, P, 2013)
"This case report describes a patient who developed severe bradycardia due to transdermal fentanyl."3.79Case report of severe bradycardia due to transdermal fentanyl. ( Hawley, P, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikeda, K1
Kobayashi, S1
Suzuki, M1
Miyata, K1
Takeuchi, M1
Yamada, T1
Honda, K1
Hawley, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study to Assess the Safety and Efficacy of Solifenacin (VESIcare) for Improving Urinary and Bladder Functions in Patients Undergoing Radiation Therapy of the Prostate[NCT01777217]Phase 48 participants (Actual)Interventional2013-02-28Terminated (stopped due to Terminated)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline to End of Study Measured by the American Urology Association Symptom Score Questionnaire (AUASS).

The AUASS score range is 1-7 (mild), 8-19 (moderate) and 20-35 (severe). The AUASS asks 7 questions scored 0-5, the scores are summed for the total score. (NCT01777217)
Timeframe: baseline and 16 weeks

InterventionScores on a scale (Median)
Solifenacin Succinate9.4
Placebo6.7

Other Studies

2 other studies available for oxybutynin and Bradycardia

ArticleYear
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:2

    Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relat

2002
Case report of severe bradycardia due to transdermal fentanyl.
    Palliative medicine, 2013, Volume: 27, Issue:8

    Topics: Analgesics, Opioid; Bradycardia; Canada; Female; Fentanyl; Humans; Middle Aged; Ovarian Neoplasms; T

2013