Page last updated: 2024-11-02

oxybutynin and Autonomic Hyperreflexia

oxybutynin has been researched along with Autonomic Hyperreflexia in 2 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Research Excerpts

ExcerptRelevanceReference
" Following a 7-day washout period, patients were evaluated via video-urodynamic study and then treatment was initiated at a dosage of 10 mg per day."2.71Effect of controlled-release oxybutynin on neurogenic bladder function in spinal cord injury. ( Chancellor, MB; Erickson, JR; Horton, J; McDermott, C; O'Leary, M; Smith, CP, 2003)
"Accelerated intravesical administration results in greater bioavailability and increased objective benefits without side effects in previously unresponsive patients compared with oral and intravesical passive diffusion oxybutynin administration."2.70Intravesical electromotive administration of oxybutynin in patients with detrusor hyperreflexia unresponsive to standard anticholinergic regimens. ( Capelli, G; Di Stasi, SM; Giannantoni, A; Massoud, R; Navarra, P; Stephen, RL; Vespasiani, G, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Leary, M1
Erickson, JR1
Smith, CP1
McDermott, C1
Horton, J1
Chancellor, MB1
Di Stasi, SM1
Giannantoni, A1
Vespasiani, G1
Navarra, P1
Capelli, G1
Massoud, R1
Stephen, RL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Randomized Study of the Safety and Efficacy of OnabotulinumtoxinA (OnaBoNT-A) Versus Oral Oxybutynin in Spinal Cord Injured Patients With Neurogenic Detrusor Overactivity (Protocol Number 11-09-10-04)[NCT01050114]Phase 336 participants (Anticipated)Interventional2013-08-31Recruiting
Incobotulinumtoxin Versus Onabotulinumtoxin in the Treatment of Patients With Overactive Bladder Syndrome[NCT03758235]Phase 3140 participants (Actual)Interventional2018-09-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for oxybutynin and Autonomic Hyperreflexia

ArticleYear
Effect of controlled-release oxybutynin on neurogenic bladder function in spinal cord injury.
    The journal of spinal cord medicine, 2003,Summer, Volume: 26, Issue:2

    Topics: Adult; Aged; Autonomic Dysreflexia; Delayed-Action Preparations; Dose-Response Relationship, Drug; F

2003
Intravesical electromotive administration of oxybutynin in patients with detrusor hyperreflexia unresponsive to standard anticholinergic regimens.
    The Journal of urology, 2001, Volume: 165, Issue:2

    Topics: Administration, Intravesical; Adolescent; Adult; Autonomic Dysreflexia; Cholinergic Antagonists; Ele

2001