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oxybutynin and Arthritis, Degenerative

oxybutynin has been researched along with Arthritis, Degenerative in 10 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Research Excerpts

ExcerptRelevanceReference
"Efficacy and tolerability of buprenorphine patches was demonstrated in chronic pain patients, regardless of age, supporting the conclusion that no age-related dose adjustment of transdermal buprenorphine is needed."7.80Is buprenorphine transdermal patch equally safe and effective in younger and elderly patients with osteoarthritis-related pain? Results of an age-group controlled study. ( Augustini, BG; Berggren, AC; Karlsson, J; Söderström, A, 2014)
" The majority of drug-related adverse events (AEs) included mild dermatitis at the application sites and occurred in 46."6.82The Long-Term Safety of S-Flurbiprofen Plaster for Osteoarthritis Patients: An Open-Label, 52-Week Study. ( Hoshino, Y; Matsumoto, H; Matsushita, I; Otsuka, N; Yataba, I, 2016)
"Adult patients with pain from osteoarthritis receiving a stable dosage of HCD/APAP (i."6.77A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain. ( Landau, CJ; McCarberg, BH; Munera, C; Ripa, SR; Wen, W, 2012)
"Efficacy and tolerability of buprenorphine patches was demonstrated in chronic pain patients, regardless of age, supporting the conclusion that no age-related dose adjustment of transdermal buprenorphine is needed."3.80Is buprenorphine transdermal patch equally safe and effective in younger and elderly patients with osteoarthritis-related pain? Results of an age-group controlled study. ( Augustini, BG; Berggren, AC; Karlsson, J; Söderström, A, 2014)
" The majority of drug-related adverse events (AEs) included mild dermatitis at the application sites and occurred in 46."2.82The Long-Term Safety of S-Flurbiprofen Plaster for Osteoarthritis Patients: An Open-Label, 52-Week Study. ( Hoshino, Y; Matsumoto, H; Matsushita, I; Otsuka, N; Yataba, I, 2016)
"Adult patients with pain from osteoarthritis receiving a stable dosage of HCD/APAP (i."2.77A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain. ( Landau, CJ; McCarberg, BH; Munera, C; Ripa, SR; Wen, W, 2012)
" The primary outcomes were pain relief for RCTs and risk of adverse effects (AEs) for observational studies."2.58Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies. ( Doherty, M; Lei, G; Li, J; Li, X; Long, H; Persson, MSM; Sarmanova, A; Wang, Y; Wei, J; Xie, D; Zeng, C; Zhang, W, 2018)
"This syndrome is usually related to anatomic variants (involving the bone structures, fibrous bands, or muscles and tendons)."1.38Supraclavicular nerve entrapment syndrome. ( Bruyère, PJ; Courtois, AC; Crielaard, JM; Douchamps, F, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (90.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Härkänen, L1
Hakomäki, H1
Huopio, J1
Kokki, H1
Korhonen, S1
Lehtonen, M1
Sjövall, S1
Kokki, M1
Zeng, C1
Wei, J1
Persson, MSM1
Sarmanova, A1
Doherty, M1
Xie, D1
Wang, Y1
Li, X1
Li, J1
Long, H1
Lei, G1
Zhang, W1
Feragalli, B1
Dugall, M1
Luzzi, R1
Ledda, A1
Hosoi, M1
Belcaro, G1
Cesarone, MR1
Ban, T1
Hirose, H1
Teraura, H1
Kotani, K1
Gotoh, T1
Therkleson, T1
Karlsson, J1
Söderström, A1
Augustini, BG1
Berggren, AC1
Yataba, I1
Otsuka, N1
Matsushita, I1
Matsumoto, H1
Hoshino, Y1
Argoff, CE1
Douchamps, F1
Courtois, AC1
Bruyère, PJ1
Crielaard, JM1
Ripa, SR1
McCarberg, BH1
Munera, C1
Wen, W1
Landau, CJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01276431]Phase 4102 participants (Actual)Interventional2011-03-31Completed
A Randomized, Double-Blind Study Evaluating the Dose Conversion From Vicodin® to Buprenorphine Transdermal System (BTDS) in Subjects With Osteoarthritis (OA) Pain[NCT00312572]Phase 3204 participants (Actual)Interventional2003-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Percentage of Subjects Who Completed the 14-day Double-blind Phase.

The indicator variable was 1 = completion, and 0 = noncompletion. For the primary efficacy analysis, the percentage of subjects who completed the double-blind phase was computed with its 95% confidence interval (CI) for each treatment regimen (starting dose of BTDS 10 or BTDS 20) across and within baseline Vicodin® stratum (15 to 22.5mg/day vs >22.5 to 30 mg/day as determined by the daily average hydrocodone dose during the run-in period). (NCT00312572)
Timeframe: 14 days

,,
InterventionPercentage of Participants (Number)
15 - 22.5 mg HCD (Stratum 1)more than 22.5 - 30 mg HCD (Stratum 2)Overall
Combined Total858284
Double-blind BTDS 10/20888587
Double-blind BTDS 20837982

Reviews

2 reviews available for oxybutynin and Arthritis, Degenerative

ArticleYear
Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies.
    British journal of sports medicine, 2018, Volume: 52, Issue:10

    Topics: Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Humans; Network M

2018
Recent developments in the treatment of osteoarthritis with NSAIDs.
    Current medical research and opinion, 2011, Volume: 27, Issue:7

    Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Osteoarthritis; S

2011

Trials

2 trials available for oxybutynin and Arthritis, Degenerative

ArticleYear
The Long-Term Safety of S-Flurbiprofen Plaster for Osteoarthritis Patients: An Open-Label, 52-Week Study.
    Clinical drug investigation, 2016, Volume: 36, Issue:8

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Contact; Female;

2016
A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:9

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Aged; Analgesics, Opioid; Anti-Infla

2012

Other Studies

6 other studies available for oxybutynin and Arthritis, Degenerative

ArticleYear
Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:12

    Topics: Administration, Cutaneous; Analgesics, Opioid; Buprenorphine; Humans; Osteoarthritis; Transdermal Pa

2023
Pycnogenol®: supplementary management of symptomatic osteoarthritis with a patch. An observational registry study.
    Minerva endocrinologica, 2019, Volume: 44, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Flavonoids; Humans; Inflammation; Knee; Male

2019
Multiple physician visits after restricting the prescription of compresses/patches in a Japanese rural community: preliminary results.
    Rural and remote health, 2019, Volume: 19, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Female; Humans; Male; Office Visits; Osteoarthriti

2019
Topical Ginger Treatment With a Compress or Patch for Osteoarthritis Symptoms.
    Journal of holistic nursing : official journal of the American Holistic Nurses' Association, 2014, Volume: 32, Issue:3

    Topics: Administration, Topical; Aged; Female; Humans; Male; Middle Aged; New Zealand; Osteoarthritis; Pain;

2014
Is buprenorphine transdermal patch equally safe and effective in younger and elderly patients with osteoarthritis-related pain? Results of an age-group controlled study.
    Current medical research and opinion, 2014, Volume: 30, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Chronic Pain; Female; Human

2014
Supraclavicular nerve entrapment syndrome.
    Joint bone spine, 2012, Volume: 79, Issue:1

    Topics: Analgesics; Antirheumatic Agents; Brachial Plexus; Clavicle; Humans; Lidocaine; Male; Middle Aged; N

2012