oxybutynin has been researched along with Anesthesia in 7 studies
oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of AH-9700 (1-[2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl] pyrrolidine fumarate; a novel sigma receptor ligand), (+)-pentazocine and 1,3-di-o-tolylguanidine (DTG) (two typical sigma receptor ligands), and oxybutynin (a currently used anti-pollakiuria drug) on cystometrograms in anesthetized rats with 30% acetone-induced cystitis." | 7.71 | Effects of AH-9700, (+)-pentazocine, DTG and oxybutynin on micturition in anesthetized rats with acetone-induced cystitis. ( Ishii, D; Kawashima, K; Oka, M; Shimizu, I, 2001) |
| "We investigated the effects of AH-9700 (1-[2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl] pyrrolidine fumarate; a novel sigma receptor ligand), (+)-pentazocine and 1,3-di-o-tolylguanidine (DTG) (two typical sigma receptor ligands), and oxybutynin (a currently used anti-pollakiuria drug) on cystometrograms in anesthetized rats with 30% acetone-induced cystitis." | 3.71 | Effects of AH-9700, (+)-pentazocine, DTG and oxybutynin on micturition in anesthetized rats with acetone-induced cystitis. ( Ishii, D; Kawashima, K; Oka, M; Shimizu, I, 2001) |
| " Under pentobarbital anesthesia, the systolic/diastolic arterial pressure oxybutynin responses were reversed and showed a dose-related systolic and diastolic hypotension." | 3.66 | Oxybutynin influence on autonomic measures in dogs. ( Korol, B; Miller, LD, 1979) |
| "The carbachol-induced increase in intravesical pressure and salivation was simultaneously recorded before and after increasing doses of test drugs administered intravenously." | 1.34 | Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model. ( Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S, 2007) |
| "Oxybutynin has been used for neurogenic bladder disorders in clinic and known to have anti-cholinergic and spasmolytic properties." | 1.32 | [Effect of 4-ethylamino-2-butynyl(2-cyclohexyl-2-phenyl) glycolate, metabolite of oxybutynin, on intra-artery administered acetylcholine-induced urinary bladder contraction in anesthetized dogs]. ( Koganei, M; Nakajima, M; Uchida, M; Yamaji, T, 2004) |
| "Oxybutynin was equipotent (ID50 approximately 0." | 1.28 | In vivo cystometrogram studies in urethane-anesthetized and conscious guinea pigs. ( Hanson, RC; Noronha-Blob, L; Peterson, JS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uchida, M | 1 |
| Nakajima, M | 1 |
| Koganei, M | 1 |
| Yamaji, T | 1 |
| Naruganahalli, KS | 1 |
| Sinha, S | 1 |
| Hegde, LG | 1 |
| Meru, AV | 1 |
| Chugh, A | 1 |
| Kumar, N | 1 |
| Gupta, JB | 1 |
| Ray, A | 1 |
| Shimizu, I | 2 |
| Kawashima, K | 2 |
| Ishii, D | 2 |
| Oku, S | 1 |
| Kohayakawa, H | 1 |
| Oka, M | 2 |
| Korol, B | 1 |
| Miller, LD | 1 |
| Morikawa, K | 1 |
| Hashimoto, S | 1 |
| Yamauchi, T | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Gomi, Y | 1 |
| Peterson, JS | 1 |
| Hanson, RC | 1 |
| Noronha-Blob, L | 1 |
7 other studies available for oxybutynin and Anesthesia
| Article | Year |
|---|---|
[Effect of 4-ethylamino-2-butynyl(2-cyclohexyl-2-phenyl) glycolate, metabolite of oxybutynin, on intra-artery administered acetylcholine-induced urinary bladder contraction in anesthetized dogs].
Topics: Acetylcholine; Anesthesia; Animals; Confidence Intervals; Dogs; Dose-Response Relationship, Drug; Fe | 2004 |
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model.
Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols; | 2007 |
Pharmacological actions of AH-9700 on micturition reflex in anesthetized rats.
Topics: Anesthesia; Animals; Cholinergic Antagonists; Dose-Response Relationship, Drug; Female; Fumarates; H | 2001 |
Effects of AH-9700, (+)-pentazocine, DTG and oxybutynin on micturition in anesthetized rats with acetone-induced cystitis.
Topics: Acetone; Anesthesia; Animals; Cystitis; Disease Models, Animal; Fumarates; Guanidines; Male; Mandeli | 2001 |
Oxybutynin influence on autonomic measures in dogs.
Topics: Anesthesia; Animals; Autonomic Nervous System; Blood Pressure; Cyclohexanes; Dogs; Female; Heart Rat | 1979 |
Inhibitory effect of inaperisone hydrochloride (inaperisone), a new centrally acting muscle relaxant, on the micturition reflex.
Topics: Anesthesia; Animals; Atropine; Baclofen; Brain; Male; Mandelic Acids; Muscle Contraction; Muscle Rel | 1992 |
In vivo cystometrogram studies in urethane-anesthetized and conscious guinea pigs.
Topics: Anesthesia; Animals; Atropine; Cystoscopy; Female; Guinea Pigs; Mandelic Acids; Parasympatholytics; | 1989 |