Page last updated: 2024-11-02

oxybutynin and Amenorrhea

oxybutynin has been researched along with Amenorrhea in 3 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Amenorrhea: Absence of menstruation.

Research Excerpts

ExcerptRelevanceReference
"Mean number of bleeding/spotting episodes was comparable across groups for both reference periods, but bleeding/spotting episodes were shorter for the EE/GSD patch than the EE/NGMN patch during reference period 1 (5."2.80A comparison of bleeding patterns and cycle control using two transdermal contraceptive systems: a multicenter, open-label, randomized study. ( Gruber, D; Lanius, V; Merz, M; Serrani, M; Skřivánek, A, 2015)
"Mean number of bleeding/spotting days was comparable across treatment groups in both reference periods (p>."2.80Bleeding pattern and cycle control of a low-dose transdermal contraceptive patch compared with a combined oral contraceptive: a randomized study. ( Bangerter, K; Kroll, R; Lynen, R; Merz, M, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ackerman, KE1
Singhal, V1
Baskaran, C1
Slattery, M1
Campoverde Reyes, KJ1
Toth, A1
Eddy, KT1
Bouxsein, ML1
Lee, H1
Klibanski, A1
Misra, M1
Gruber, D1
Skřivánek, A1
Serrani, M1
Lanius, V1
Merz, M2
Kroll, R1
Lynen, R1
Bangerter, K1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes[NCT00946192]Phase 3121 participants (Actual)Interventional2009-05-31Completed
Menstrual Cycle, Amenorrhea and Contraception in Elite Female Athletes: Impact on Performance, Health and the Athlete's Biological Passport[NCT05028959]80 participants (Anticipated)Interventional2021-09-15Not yet recruiting
Transdermal Contraception Patch: EU Cycle Control Study Versus EVRA[NCT00984789]Phase 3393 participants (Actual)Interventional2009-05-31Completed
Multi-Center, Double-Blind, Double-Dummy, Randomized, Parallel-Group Study to Evaluate Cycle Control, Bleeding Pattern, Blood Pressure, Lipid and Carbohydrate Metabolism of the Transdermal Contraceptive Patch (Material no. 80876395 / 2.1 mg Gestodene and [NCT00920985]Phase 3346 participants (Actual)Interventional2009-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Lumbar Bone Mineral Density

Change in bone density with transdermal estrogen versus oral estrogen or no estrogen in amenorrheic athletes (NCT00946192)
Timeframe: 12 months

Interventiong/cm^2 (Mean)
Estrogen Patch0.025
Estrogen Pill0.008
Control0.012

Change in Total Volumetric Bone Mineral Density (Tibia)

Change in total volumetric bone density at the tibia with transdermal estrogen versus oral estrogen or no estrogen in amenorrheic athletes (NCT00946192)
Timeframe: 12 months

Interventionmg HA/cm^3 (Mean)
Estrogen Patch7.01
Estrogen Pill1.17
Control3.71

Trials

3 trials available for oxybutynin and Amenorrhea

ArticleYear
Oestrogen replacement improves bone mineral density in oligo-amenorrhoeic athletes: a randomised clinical trial.
    British journal of sports medicine, 2019, Volume: 53, Issue:4

    Topics: Absorptiometry, Photon; Administration, Oral; Adolescent; Adult; Amenorrhea; Athletes; Bone Density;

2019
Oestrogen replacement improves bone mineral density in oligo-amenorrhoeic athletes: a randomised clinical trial.
    British journal of sports medicine, 2019, Volume: 53, Issue:4

    Topics: Absorptiometry, Photon; Administration, Oral; Adolescent; Adult; Amenorrhea; Athletes; Bone Density;

2019
Oestrogen replacement improves bone mineral density in oligo-amenorrhoeic athletes: a randomised clinical trial.
    British journal of sports medicine, 2019, Volume: 53, Issue:4

    Topics: Absorptiometry, Photon; Administration, Oral; Adolescent; Adult; Amenorrhea; Athletes; Bone Density;

2019
Oestrogen replacement improves bone mineral density in oligo-amenorrhoeic athletes: a randomised clinical trial.
    British journal of sports medicine, 2019, Volume: 53, Issue:4

    Topics: Absorptiometry, Photon; Administration, Oral; Adolescent; Adult; Amenorrhea; Athletes; Bone Density;

2019
A comparison of bleeding patterns and cycle control using two transdermal contraceptive systems: a multicenter, open-label, randomized study.
    Contraception, 2015, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Amenorrhea; Austria; Contraceptive Agents, Female; Czech Republic; Drug Combinati

2015
Bleeding pattern and cycle control of a low-dose transdermal contraceptive patch compared with a combined oral contraceptive: a randomized study.
    Contraception, 2015, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Amenorrhea; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Double-

2015