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oxotremorine and Tremor

oxotremorine has been researched along with Tremor in 156 studies

Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"Effect of zonisamide on harmaline- or oxotreorine-induced tremors, and tacrine-induced tremulous jaw movements (TJMs) was studied."7.74Effects of zonisamide on experimental tremors in rats. ( Hama, K; Kajimoto, Y; Kondo, T; Miwa, H, 2008)
" The effects of oxotremorine (OXO) on autonomic functions and tremor were examined in mice lacking alpha5 nAChR subunits (alpha5-/-) and compared with those in wild-type (WT) control mice."7.72Nicotinic acetylcholine receptor alpha5 subunits modulate oxotremorine-induced salivation and tremor. ( Chapman, J; Korczyn, AD; Orr-Urtreger, A; Rabinowitz, R; Wang, N, 2004)
") significantly enhanced harmine- but not oxotremorine-induced tremors in mice."7.70Enhancement of serotonergic neural activity contributes to cyclosporine-induced tremors in mice. ( Kanaya, A; Kataoka, Y; Matsunaga, K; Oishi, R; Shuto, H; Sueyasu, M, 1998)
" The present article investigated central responses (tremor) and peripheral responses (chromodacryorrhea) subsequent to the administration of oxotremorine to young (3-6 months of age) and aged rats (24-30 months of age)."7.70Differences in central and peripheral responses to oxotremorine in young and aged rats. ( Carlini, EA; Espínola, EB; Oliveira, MG, 1999)
"Two subseries of nonquaternized (5a-10a) and quaternized derivatives (5b-10b) related to oxotremorine and oxotremorine-M were synthesized and tested."7.70Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M. ( Ballabeni, V; Barocelli, E; Bertoni, S; Chiavarini, M; Conti, P; Dallanoce, C; De Amici, M; De Micheli, C; Impicciatore, M, 1999)
"Effects of beta-blockers (propranolol, arotinolol and nipradilol) and a Ca2+ channel blocker (nicardipine) on oxotremorine-induced tremor were studied in common marmosets."7.70Effects of beta-blockers and nicardipine on oxotremorine-induced tremor in common marmosets. ( Iwata, S; Mitsuda, M; Nomoto, M, 1999)
"To characterize the tail-tremor and locomotor hyperactivity induced by repeated nicotine administration, the effects of nicotinic, alpha-adrenergic and dopaminergic blockers were investigated in rats."7.69Characteristics of tail-tremor induced by nicotine in rats. ( Gomita, Y; Oishi, R; Suemaru, K, 1994)
"The effect of nipradilol, a nonselective beta-adrenergic receptor blocker with nitroglycerin-like vasodilating activity, on oxotremorine-induced tremor was studied in mice."7.69Effect of nipradilol, a beta-adrenergic blocker with vasodilating activity, on oxotremorine-induced tremor in mice. ( Fukuda, T; Iwata, S; Nomoto, M, 1996)
"Hypothermia and tremor responses of oxotremorine and eserine were studied in rats after several T3 treatment regimens."7.68Triiodothyronine (T3) modifies cholinergic-induced hypothermia and tremor in rats. ( Almeida, OM; Santos, R, 1993)
"Central antimuscarinic actions of dopamine receptor agonists: N,N-dipropylaminotetrain (TL-68) and 2-di-n-propylamino-4,7-dimethoxyindane (RDS-127), were evaluated against oxotremorine-induced tremors in mice."7.68Dopamine receptor agonists, N,N-dipropyl-2-aminotetralin (TL-68) and 2-di-n-propylamino-4,7-dimethoxyindane (RDS-127) antagonize oxotremorine-induced tremors by antimuscarinic action in mice. ( Ilhan, M; Sahin, I; Tuncer, M, 1990)
"A series of phenyl-substituted analogues of the muscarinic agent oxotremorine (1) have been prepared."7.68Phenyl-substituted analogues of oxotremorine as muscarinic antagonists. ( Hacksell, U; Nilsson, BM; Ringdahl, B; Vargas, HM, 1992)
"The enantiomers of three 5-methyl-2-pyrrolidone analogues of the muscarinic agent oxotremorine (1) were synthesized."7.67Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones. ( Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M, 1985)
"A series of tertiary 3- and 4-haloalkylamines related to the muscarinic agent oxotremorine was synthesized."7.67Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1988)
" Diazepam has been reported to inhibit both the tremor and mechanism of cerebellar cyclic GMP caused by harmaline by a neurotransmission in the cerebellum."7.67Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP. ( Dole, VP; Gentry, RT; Rappaport, MS; Schneider, DR, 1984)
"Organochlorine insecticides such as DDT and chlordecone produce tremor in exposed individuals."7.67Studies on the mechanism of chlordecone-induced tremor in rats. ( Gerhart, JM; Hong, JS; Tilson, HA, 1985)
"The enantiomers of the oxotremorine analog N-[4-(2-chloromethylpyrrolidine)-2-butynyl]-2-pyrrolidone (BM 130) were synthesized."7.67Muscarinic actions and receptor binding of the enantiomers of BM 130, an alkylating analog of oxotremorine. ( Jenden, DJ; Katz, ED; Ringdahl, B; Roch, M, 1989)
"A tremor monitor was constructed and tested that quantitates soman- and oxotremorine-induced tremors."7.67Device for quantitating tremor activity in mice: antitremor activity of atropine versus soman- and oxotremorine-induced tremors. ( Clement, JG; Dyck, WR, 1989)
"Propranolol in low doses antagonized and in higher doses facilitated oxotremorine-induced tremor (Oxo-tremor) in mice."7.67Cholinergic involvement in the modulation of oxotremorine-tremor in mice by propranolol. ( Alkondon, M; Ray, A; Sen, P, 1985)
"Oxotremorine-induced tremor activity in mice was suppressed by pretreatment with either L-dopa or atropine."7.67A selective potentiation by naloxone of L-dopa but not atropine suppression of oxotremorine-induced tremor in mice. ( Lucas, TS; Quock, RM, 1985)
"The muscarinic agonist oxotremorine was used to induce tremor in rats pretreated with methylatropine."7.67Modulation of oxotremorine-induced tremor by central beta-adrenoceptors. ( Almgren, O; Hallberg, H, 1987)
"Tremor induced by TRH and oxotremorine was recorded by a capacitance transducer, and its intensity and frequency were evaluated using power arrays."7.67[Power spectral analysis of tremor induced by TRH and oxotremorine in mice]. ( Fukuda, T; Izumi, K; Koja, T; Nomoto, M; Shimizu, T, 1986)
"The muscarinic actions of several analogs of oxotremorine were compared in the mouse."7.67Regional differences in receptor reserve for analogs of oxotremorine in vivo: implications for development of selective muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1987)
"The pharmacological effects of N-[4-(2-bromoethylmethylamino)-2-butynyl]-2-pyrrolidone (BR 401) were compared in the mouse with those of N-[4-(2-chloroethylmethylamino)-2-butynl]-2-pyrrolidone (BM 123) and oxotremorine."7.67Muscarinic actions of an N-methyl-N-2-bromoethylamino analog of oxotremorine (BR 401) in the mouse. ( Jenden, DJ; Ringdahl, B, 1987)
"A peripheral and cerebral cholinergic syndrome was induced in mice by oxotremorine administration; pretreatment orally with cytidine diphosphocholine (CDP-choline) does not potentiate this syndrome and even antagonizes oxotremorine-induced salivation."7.67Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine. ( Boismare, F; Chadelaud, M; Chretien, P; Daoust, M; Moore, N; Saligaut, C, 1985)
"Cholecystokinin octapeptide (CCK-8), ceruletide (caerulein, CER) and 10 analogues of ceruletide, were studied in mice for antagonism of the tremors induced by harmine (5 mg/kg, s."7.66Cholecystokinin octapeptide (CCK-8), ceruletide and analogues of ceruletide: effects on tremors induced by oxotremorine, harmine and ibogaine. A comparison with prolyl-leucylglycine amide (MIF), anti-Parkinsonian drugs and clonazepam. ( Zetler, G, 1983)
"Pretreatment with the catecholamine precursor L-DOPA but not the narcotic antagonist naloxone suppressed the tremorigenic effect of oxotremorine in mice."7.66Potentiation by naloxone of the anti-oxotremorine effect of L-DOPA. ( Lucas, TS; Quock, RM, 1983)
"The efficacy of an oral treatment of cytidine diphosphate choline (CDP-choline, citicoline, Somazina) is studied with reference to the effects on parasympathetic stimulation provoked by oxotremorine administration in mice."7.66Pharmacological study of oral CDP-choline. Interaction with oxotremorine on the parasympathetic system. ( Ortiz, JA; Sacristán, A; Tornos, ME, 1983)
"A number of secondary and tertiary amines as well as quaternary ammonium compounds, obtained by structural modification of the amino group of oxotremorine (1) and its acetamide analogue (14), were investigated for muscarinic and antimuscarinic activity in vivo and in vitro."7.66Muscarinic activity of some secondary and tertiary amines and quaternary ammonium salts structurally related to oxotremorine. ( Dahlbom, R; Jenden, DJ; Resul, B; Ringdahl, B, 1983)
"Harmine, a hallucinogen with potent monoamine oxidase inhibitory properties, induced abnormal behavior, including tremor, scratching, head twitch and cage biting, in the mouse."7.66Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. ( Fujiwara, M; Hashimoto, Y; Kataoka, Y; Kawanishi, K; Ueki, S, 1981)
"1 The enantiomers of some analogues of the central muscarinic agent, oxotremorine, were prepared and investigated for tremorogenic and tremorolytic activity in intact mice and for muscarinic and antimuscarinic activity on the isolated ileum of the guinea-pig."7.66Stereochemical requirements for central and peripheral muscarinic and antimuscarinic activity of some acetylenic compounds related to oxotremorine. ( Dahlbom, R; Jenden, DJ; Resul, B; Ringdahl, B, 1982)
"The action of the benzomorphan narcotic antagonists Mr-1452 and Mr-2266 and their respective (+) isomers Mr-1453 and Mr-2267 as well as the antimuscarinic agent atropine upon oxotremorine (OTMN)-induced analgesia, tremor, and hypothermia were investigated in mice."7.66Some observations on the effects of enantiomers of two benzomorphan narcotic antagonists and atropine on analgesia, tremor and hypothermia produced by oxotremorine. ( Ben-Sreti, MM; Sewell, RD; Upton, N, 1982)
"The role of peripheral catecholamines in mediating the pressor and tremorigenic effects of oxotremorine were investigated in conscious rats."7.66Peripheral catecholamines mediate certain responses to central cholinergic receptor stimulation by oxotremorine. ( Kopin, IJ; Weinstock, M; Zavadil, AP, 1980)
"Oxotremorine, 0."7.66The role of peripheral catecholamines in oxotremorine tremor in the rat and its antagonism by beta adrenoceptor blocking agents. ( Chiueh, CC; Kopin, IJ; Rosin, AJ; Weinstock, M; Zavadil, AP, 1978)
"Fourteen di- and tripeptide analogues of MIF, Pro-Leu-Gly-NH2, have been synthesized and assayed for inhibition of oxotremorine-induced tremor."7.66Tripeptide analogues of melanocyte-stimulating hormone release-inhibiting hormone (Pro-Leu-Gly-NH2) as inhibitors of oxotremorine-induced tremor. ( Björkman, S; Castensson, S; Sievertsson, H, 1979)
"The stereoisomers of some analogues of oxotremorine containing two chiral centres, one in the 1-position of the butynyl chas are oxotremorine antagonists."7.66Stereoselectivity of some oxotremorine antagonists containing two chiral centres. ( Dahlbom, R; Resul, B; Ringdahl, B, 1979)
"Meperidine (20 and 40 mg/kg, IP) did not block the cholinergic effects (tremor, salivation, and tearing) produced by oxotremorine (0."7.66Meperidine does not block the cholinergic effects of oxotremorine. ( Leander, JD, 1979)
"Administration of oxotremorine to mice produced centrally-mediated effects, such as catalepsy and tremor, and peripheral muscarinic actions, such as diarrhoea and lachrymation."7.66Amantadine antagonism of oxotremorine effects. ( Eshel, Y; Korczyn, AD, 1979)
"Tubocurarine tremor and shivering show identical topography in different muscle groups and identical frequency patterns of the EMG."7.66[Comparative characteristics of mechanisms regulating tubocurarine and cold tremor]. ( Burachevskaia, LE; Lupandin, IuV, 1978)
"The beta-adrenoceptor blockers propranolol, PhQA33 and LB-46 exhibited appreciable activity against tremorine-(TMN) and oxotremorine-(OTMN) induced tremor, whereas pronethalol, (+)-H56/28, (-)-H56/28, Kö-592 and L(+)-INPEA possessed weak action."7.65Tremorine-oxotremorine-induced tremor, hypothermia and analgesia, and physostigmine toxicity, in mice after pretreatment with beta-adrenoceptor antagonists. ( Barar, FS; Madan, BR, 1976)
"5-25 mg/kg) were found to restore and to intensify the oxotremorine-induced tremor in mice when injected i."7.65Thyrotropin releasing hormone (TRH): restoration of oxotremorine tremor in mice. Comparison with quipazine, a serotoninergic and dopaminergic stimulant. ( Kruse, H, 1976)
"Two oxotremorine antagonists have been examined using oxotremorine as the tremor salivation inducer and the ratios between the central and peripheral nervous systems determined."7.65The central and peripheral effectiveness of two oxotremorine-antagonists determined using oxotremorine-induced tremor and salivation. ( Eicholzer, A; Ogren, SO, 1977)
"Cyclizine was observed to induce generalized chorea in a patient with mild lingual-facial-buccal dyskinesias."7.65Cyclizine-induced chorea. Observations on the influence of cyclizine on dopamine-related movement disorders. ( Klawans, HL; Moskovitz, C, 1977)
" The effect of various agents injected into the cerebral ventricles of the mouse, upon the tremor and hypothermia produced by oxotremorine (0."7.65Modification of oxotremorine tremor and hypothermia by injections of drugs into the cerebral ventricles of the mouse. ( Doggett, NS; O'Farrell, SA, 1976)
" The influence of propranolol on the neuromuscular, tremor-producing and muscarinic effects of oxotremorine was examined."7.65Antioxotremorine action of propranolol. ( Ganguly, DK, 1976)
"Oxotremorine tremor has in common with shivering its frequency range (10-28 Hz) and the co-contraction of flexors and extensors."5.29Role of the stretch reflex in oxotremorine tremor. ( Decima, EE, 1996)
"Tremor was evaluated using spectral analytical techniques."5.28Interactions between ethanol and pantothenic acid on tremor and behavior in squirrel monkeys. ( Newland, MC; Rivera-Calimlim, L; Weiss, B, 1992)
" The results of oxotremorine treatment suggested that they undergo strong suppression of muscarinic type acetylcholine receptors (mAChRs) functions, and that the damage in the GM3-only mice is due to a mAChR receptor deficit."3.76Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice. ( Egashira, N; Fujiwara, M; Fukue, Y; Furukawa, K; Iwasaki, K; Mishima, K; Ohmi, Y; Sugiura, Y; Tajima, O, 2010)
" Variation across strains was detected in terms of acoustic startle, prepulse inhibition, and the physiologic effects of the muscarinic agonist oxotremorine."3.76Lack of association of a spontaneous mutation of the Chrm2 gene with behavioral and physiologic phenotypic differences in inbred mice. ( Arnold, J; Ding, M; Hughes, LF; Ramkumar, V; Toth, LA; Trammell, RA; Turner, J, 2010)
") enhanced tremors induced by oxotremorine, a muscarinic M(1) receptor agonist."3.74Kamikihi-to, a Kampo medicine, ameliorates impairment of spatial memory in rats. ( Egashira, N; Fujiwara, M; Iwasaki, K; Kurauchi, K; Manome, N; Matsumoto, Y; Mishima, K; Shoyama, Y, 2007)
"Effect of zonisamide on harmaline- or oxotreorine-induced tremors, and tacrine-induced tremulous jaw movements (TJMs) was studied."3.74Effects of zonisamide on experimental tremors in rats. ( Hama, K; Kajimoto, Y; Kondo, T; Miwa, H, 2008)
" We investigated here muscarinic receptor reactivity in NVH lesioned animals by measuring the effects of the muscarinic receptor agonist oxotremorine on physiological responses known to be modulated by these receptors such as body temperature, salivation, tremor, pain, and prepulse inhibition of the acoustic startle (PPI)."3.73Alterations in behavioral responses to a cholinergic agonist in post-pubertal rats with neonatal ventral hippocampal lesions: relationship to changes in muscarinic receptor levels. ( Laplante, F; Nakagawasai, O; Quirion, R; Srivastava, LK, 2005)
"), inhibited negative inotropic (left ventricular dP/dt) effects caused by oxotremorine, a nonselective muscarinic agonist (p < 0."3.73In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine. ( Howell, G; Jenkins, C; Lineberry, B; Rockhold, R; West, L; Yokum, D, 2005)
" Low dose citalopram reversed both scopolamine- and THC-induced impairment of spatial memory, suppressed ECS-induced immobilization reversed the THC-induced decrease of acetylcholine (ACh) release in the dorsal hippocampus in vivo microdialysis, and enhanced tremors induced by oxotremorine, a muscarinic M1 receptor agonist."3.73Low dose citalopram reverses memory impairment and electroconvulsive shock-induced immobilization. ( Egashira, N; Fujioka, M; Fujiwara, M; Iwasaki, K; Matsumoto, Y; Matsushita, M; Mishima, K; Nishimura, R; Shoyama, Y, 2006)
" Further, the same dose of Ninjin-yoei-to enhanced oxotremorine-induced tremors in mice."3.72Ninjin-yoei-to (Ren-Shen-Yang-Rong-Tang) and Polygalae radix improves scopolamine-induced impairment of passive avoidance response in mice. ( Egashira, N; Hattori, N; Ishige, A; Sakakibara, I; Yuzurihara, M, 2003)
"This study examined the effects of acute and chronic desipramine, 24-h total sleep deprivation (TSD) and 96-h REM sleep deprivation (REMSD) on physostigmine-induced hypothermia, analgesia and behaviour."3.72Functional reactivity of central cholinergic systems following desipramine treatments and sleep deprivation. ( Murugaiah, KD; Ukponmwan, OE, 2003)
" The effects of oxotremorine (OXO) on autonomic functions and tremor were examined in mice lacking alpha5 nAChR subunits (alpha5-/-) and compared with those in wild-type (WT) control mice."3.72Nicotinic acetylcholine receptor alpha5 subunits modulate oxotremorine-induced salivation and tremor. ( Chapman, J; Korczyn, AD; Orr-Urtreger, A; Rabinowitz, R; Wang, N, 2004)
") also potentiates oxotremorine-induced tremors in mice, in a dose-dependent manner, and this effect was completely prevented by atropine."3.71Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline. ( Cunha, GM; Farias, PA; Viana, GS, 2002)
" The standard muscarinic agonists oxotremorine and pilocarpine were both active in these tests but showed little separation between efficacy and cholinergic side effects."3.70Muscarinic agonists with antipsychotic-like activity: structure-activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity. ( Bymaster, FP; Calligaro, DO; DeLapp, NW; Fink-Jensen, A; Jeppesen, L; Olesen, PH; Rasmussen, T; Rimvall, K; Sauerberg, P; Shannon, HE; Sheardown, MJ; Swedberg, MD; Thomsen, C; Thøgersen, H; Ward, JS, 1998)
") significantly enhanced harmine- but not oxotremorine-induced tremors in mice."3.70Enhancement of serotonergic neural activity contributes to cyclosporine-induced tremors in mice. ( Kanaya, A; Kataoka, Y; Matsunaga, K; Oishi, R; Shuto, H; Sueyasu, M, 1998)
" The present article investigated central responses (tremor) and peripheral responses (chromodacryorrhea) subsequent to the administration of oxotremorine to young (3-6 months of age) and aged rats (24-30 months of age)."3.70Differences in central and peripheral responses to oxotremorine in young and aged rats. ( Carlini, EA; Espínola, EB; Oliveira, MG, 1999)
"Two subseries of nonquaternized (5a-10a) and quaternized derivatives (5b-10b) related to oxotremorine and oxotremorine-M were synthesized and tested."3.70Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M. ( Ballabeni, V; Barocelli, E; Bertoni, S; Chiavarini, M; Conti, P; Dallanoce, C; De Amici, M; De Micheli, C; Impicciatore, M, 1999)
"Effects of beta-blockers (propranolol, arotinolol and nipradilol) and a Ca2+ channel blocker (nicardipine) on oxotremorine-induced tremor were studied in common marmosets."3.70Effects of beta-blockers and nicardipine on oxotremorine-induced tremor in common marmosets. ( Iwata, S; Mitsuda, M; Nomoto, M, 1999)
"To characterize the tail-tremor and locomotor hyperactivity induced by repeated nicotine administration, the effects of nicotinic, alpha-adrenergic and dopaminergic blockers were investigated in rats."3.69Characteristics of tail-tremor induced by nicotine in rats. ( Gomita, Y; Oishi, R; Suemaru, K, 1994)
"The potency of centrally administered non-selective (atropine and N-methyl scopolamine) and putatively selective muscarinic antagonists (pirenzepine, AF-DX 116 and 4-DAMP) in inhibition of oxotremorine-induced hypothermia, tremor and salivation in male mice has been compared with their potency in vitro in three functional systems, where muscarinic effects are mediated preferentially by M1 (i."3.69The involvement of muscarinic receptor subtypes in the mediation of hypothermia, tremor, and salivation in male mice. ( Lembøl, HL; Sánchez, C, 1994)
"The effect of nipradilol, a nonselective beta-adrenergic receptor blocker with nitroglycerin-like vasodilating activity, on oxotremorine-induced tremor was studied in mice."3.69Effect of nipradilol, a beta-adrenergic blocker with vasodilating activity, on oxotremorine-induced tremor in mice. ( Fukuda, T; Iwata, S; Nomoto, M, 1996)
" 3) The behaviorally effective doses of (+/-)-rolipram and its isomers also enhanced the oxotremorine-induced tremors in mice."3.69Rolipram and its optical isomers, phosphodiesterase 4 inhibitors, attenuated the scopolamine-induced impairments of learning and memory in rats. ( Egawa, T; Fujiwara, M; Iwasaki, K; Matsumoto, Y; Mishima, K, 1997)
"A series of acetylenic imidazoles related to oxotremorine (1a) were prepared and evaluated as cholinergic agents with in vitro binding assays and in vivo pharmacological tests in mice."3.68Cholinergic activity of acetylenic imidazoles and related compounds. ( Chidester, CG; Collins, RJ; Francis, JW; Heier, RF; Moon, MW; Morris, JK; Russell, RR; Sage, GP; Sethy, VH, 1991)
"We studied the effect of various kinds of beta-adrenergic blockers on oxotremorine-, harmaline- and thyrotropin-releasing hormone (TRH)-induced tremors in mice."3.68Effects of beta-adrenergic blockers on drug-induced tremors. ( Fukuda, T; Iwata, S; Nomoto, M, 1993)
"Hypothermia and tremor responses of oxotremorine and eserine were studied in rats after several T3 treatment regimens."3.68Triiodothyronine (T3) modifies cholinergic-induced hypothermia and tremor in rats. ( Almeida, OM; Santos, R, 1993)
"Central antimuscarinic actions of dopamine receptor agonists: N,N-dipropylaminotetrain (TL-68) and 2-di-n-propylamino-4,7-dimethoxyindane (RDS-127), were evaluated against oxotremorine-induced tremors in mice."3.68Dopamine receptor agonists, N,N-dipropyl-2-aminotetralin (TL-68) and 2-di-n-propylamino-4,7-dimethoxyindane (RDS-127) antagonize oxotremorine-induced tremors by antimuscarinic action in mice. ( Ilhan, M; Sahin, I; Tuncer, M, 1990)
"A series of phenyl-substituted analogues of the muscarinic agent oxotremorine (1) have been prepared."3.68Phenyl-substituted analogues of oxotremorine as muscarinic antagonists. ( Hacksell, U; Nilsson, BM; Ringdahl, B; Vargas, HM, 1992)
" Oxotremorine-induced tremor and salivation in mice were delayed after extremely high dosage of levocabastine; however, these were much less effective than those seen after diphenhydramine and ketotifen."3.68Central effect of the potent long-acting H1-antihistamine levocabastine. ( Aoki, I; Kamei, C; Tasaka, K; Tsujimoto, S; Yoshida, T, 1990)
"The enantiomers of three 5-methyl-2-pyrrolidone analogues of the muscarinic agent oxotremorine (1) were synthesized."3.67Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones. ( Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M, 1985)
"A series of tertiary 3- and 4-haloalkylamines related to the muscarinic agent oxotremorine was synthesized."3.67Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1988)
" Diazepam has been reported to inhibit both the tremor and mechanism of cerebellar cyclic GMP caused by harmaline by a neurotransmission in the cerebellum."3.67Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP. ( Dole, VP; Gentry, RT; Rappaport, MS; Schneider, DR, 1984)
"Male and female rats of two lines psychogenetically selected for bipolar extremes in shuttle box avoidance were evaluated for tremor, salivation, chromodacryoorhea, and hypothermia following treatment with the muscarinic cholinergic agonist oxotremorine."3.67Differential response to cholinergic stimulation in psychogenitically selected rat lines. ( Driscoll, P; Gentsch, C; Martin, JR, 1984)
" Chronic infusion resulted in mice that were supersensitive to the hypothermia and tremor produced by the muscarinic agonist, oxotremorine."3.67Chronic scopolamine treatment and brain cholinergic function. ( Artman, LD; Burch, JB; Collins, AC; Marks, MJ; O'Connor, MF, 1984)
"Organochlorine insecticides such as DDT and chlordecone produce tremor in exposed individuals."3.67Studies on the mechanism of chlordecone-induced tremor in rats. ( Gerhart, JM; Hong, JS; Tilson, HA, 1985)
" Both minaprine and SR 95070B potentiated the tremorigenic effect of oxotremorine without inducing tremor when injected alone."3.67Cholinomimetic activities of minaprine. ( Biziere, K; Kan, JP; Perio, A; Steinberg, R; Terranova, JP; Worms, P, 1989)
"The anticholinergic effect of atropine, imipramine, clomipramine and metapramine was evaluated on oxotremorine induced trembling in the mouse as well as on contractions of the isolated guinea pig ileum induced by electrical stimulation of the mesenteric plexus."3.67[Evaluation of the central anticholinergic activity of antidepressants. Comparison of two experimental methods]. ( Billa, JP; Dufour, P; Fabre, J; Roquebert, J, 1989)
"The enantiomers of the oxotremorine analog N-[4-(2-chloromethylpyrrolidine)-2-butynyl]-2-pyrrolidone (BM 130) were synthesized."3.67Muscarinic actions and receptor binding of the enantiomers of BM 130, an alkylating analog of oxotremorine. ( Jenden, DJ; Katz, ED; Ringdahl, B; Roch, M, 1989)
"A tremor monitor was constructed and tested that quantitates soman- and oxotremorine-induced tremors."3.67Device for quantitating tremor activity in mice: antitremor activity of atropine versus soman- and oxotremorine-induced tremors. ( Clement, JG; Dyck, WR, 1989)
"Propranolol in low doses antagonized and in higher doses facilitated oxotremorine-induced tremor (Oxo-tremor) in mice."3.67Cholinergic involvement in the modulation of oxotremorine-tremor in mice by propranolol. ( Alkondon, M; Ray, A; Sen, P, 1985)
"Oxotremorine-induced tremor activity in mice was suppressed by pretreatment with either L-dopa or atropine."3.67A selective potentiation by naloxone of L-dopa but not atropine suppression of oxotremorine-induced tremor in mice. ( Lucas, TS; Quock, RM, 1985)
"The muscarinic agonist oxotremorine was used to induce tremor in rats pretreated with methylatropine."3.67Modulation of oxotremorine-induced tremor by central beta-adrenoceptors. ( Almgren, O; Hallberg, H, 1987)
" into male mice potentiated and prolonged the oxotremorine and physostigmine-induced tremor in a dose-dependent manner."3.67In vivo and in vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker. ( Bartfai, T; Danielsson, E; Nordström, O; Ogren, SO; Peterson, LL, 1985)
" Phenotypically normal rats showed tremor in response to harmaline, a drug that acts on the inferior olive to produce bursting in the climbing fiber pathway."3.67Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt). ( Beales, M; Lorden, JF; Lutes, J; McKeon, TW; Oltmans, GA, 1985)
"Tremor induced by TRH and oxotremorine was recorded by a capacitance transducer, and its intensity and frequency were evaluated using power arrays."3.67[Power spectral analysis of tremor induced by TRH and oxotremorine in mice]. ( Fukuda, T; Izumi, K; Koja, T; Nomoto, M; Shimizu, T, 1986)
"The acute and chronic effects of the centrally active oxotremorine analog, BM-5, [N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)-acetamide] were examined in rats and mice."3.67BM-5, a centrally active partial muscarinic agonist with low tremorogenic activity. In vivo and in vitro studies. ( Bartfai, T; Consolo, S; Engström, C; Ladinsky, H; Undén, A, 1987)
" In addition, although these mice showed no deficits in baseline rotorod performance, challenge with the cholinergic agonist oxotremorine revealed that MPP+-treated mice exhibited an increased sensitivity to the disruptive effects of the drug at each dose and time point."3.67Increased sensitivity of mice to tremorogenic agents following MPP+. ( Wagner, GC; Walsh, SL, 1987)
"Rolipram, in contrast to the tricyclic antidepressants amitriptyline and imipramine or the acetylcholine receptor antagonist atropine, failed to antagonize the salivation, hypothermia, or tremor caused in mice by the muscarinic receptor agonists pilocarpine or oxotremorine."3.67Absence of anticholinergic activity of rolipram, an antidepressant with a novel mechanism of action, in three different animal models in vivo. ( Löschmann, PA; Pietzuch, P; Wachtel, H, 1988)
"The muscarinic actions of several analogs of oxotremorine were compared in the mouse."3.67Regional differences in receptor reserve for analogs of oxotremorine in vivo: implications for development of selective muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1987)
"The pharmacological effects of N-[4-(2-bromoethylmethylamino)-2-butynyl]-2-pyrrolidone (BR 401) were compared in the mouse with those of N-[4-(2-chloroethylmethylamino)-2-butynl]-2-pyrrolidone (BM 123) and oxotremorine."3.67Muscarinic actions of an N-methyl-N-2-bromoethylamino analog of oxotremorine (BR 401) in the mouse. ( Jenden, DJ; Ringdahl, B, 1987)
"The dose-effect of oxotremorine upon the onset, duration and magnitude of tremor and salivation was studied in both mice and rats."3.67Serotonergic potentiation of muscarinic agonist evoked tremor and salivation in rat and mouse. ( Bartfai, T; Carlsson, S; Ogren, SO, 1985)
"A peripheral and cerebral cholinergic syndrome was induced in mice by oxotremorine administration; pretreatment orally with cytidine diphosphocholine (CDP-choline) does not potentiate this syndrome and even antagonizes oxotremorine-induced salivation."3.67Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine. ( Boismare, F; Chadelaud, M; Chretien, P; Daoust, M; Moore, N; Saligaut, C, 1985)
"Cholecystokinin octapeptide (CCK-8), ceruletide (caerulein, CER) and 10 analogues of ceruletide, were studied in mice for antagonism of the tremors induced by harmine (5 mg/kg, s."3.66Cholecystokinin octapeptide (CCK-8), ceruletide and analogues of ceruletide: effects on tremors induced by oxotremorine, harmine and ibogaine. A comparison with prolyl-leucylglycine amide (MIF), anti-Parkinsonian drugs and clonazepam. ( Zetler, G, 1983)
"Pretreatment with the catecholamine precursor L-DOPA but not the narcotic antagonist naloxone suppressed the tremorigenic effect of oxotremorine in mice."3.66Potentiation by naloxone of the anti-oxotremorine effect of L-DOPA. ( Lucas, TS; Quock, RM, 1983)
"The efficacy of an oral treatment of cytidine diphosphate choline (CDP-choline, citicoline, Somazina) is studied with reference to the effects on parasympathetic stimulation provoked by oxotremorine administration in mice."3.66Pharmacological study of oral CDP-choline. Interaction with oxotremorine on the parasympathetic system. ( Ortiz, JA; Sacristán, A; Tornos, ME, 1983)
"A number of secondary and tertiary amines as well as quaternary ammonium compounds, obtained by structural modification of the amino group of oxotremorine (1) and its acetamide analogue (14), were investigated for muscarinic and antimuscarinic activity in vivo and in vitro."3.66Muscarinic activity of some secondary and tertiary amines and quaternary ammonium salts structurally related to oxotremorine. ( Dahlbom, R; Jenden, DJ; Resul, B; Ringdahl, B, 1983)
" Finally, minaprine does not antagonize either oxotremorine-induced tremors or physiostigmine-induced lethality."3.66Pharmacological evaluation of minaprine dihydrochloride, a new psychotropic drug. ( Bizière, K; Kan, JP; Muyard, JP; Roncucci, R; Souilhac, J, 1982)
"Harmine, a hallucinogen with potent monoamine oxidase inhibitory properties, induced abnormal behavior, including tremor, scratching, head twitch and cage biting, in the mouse."3.66Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. ( Fujiwara, M; Hashimoto, Y; Kataoka, Y; Kawanishi, K; Ueki, S, 1981)
"1 The enantiomers of some analogues of the central muscarinic agent, oxotremorine, were prepared and investigated for tremorogenic and tremorolytic activity in intact mice and for muscarinic and antimuscarinic activity on the isolated ileum of the guinea-pig."3.66Stereochemical requirements for central and peripheral muscarinic and antimuscarinic activity of some acetylenic compounds related to oxotremorine. ( Dahlbom, R; Jenden, DJ; Resul, B; Ringdahl, B, 1982)
"The action of the benzomorphan narcotic antagonists Mr-1452 and Mr-2266 and their respective (+) isomers Mr-1453 and Mr-2267 as well as the antimuscarinic agent atropine upon oxotremorine (OTMN)-induced analgesia, tremor, and hypothermia were investigated in mice."3.66Some observations on the effects of enantiomers of two benzomorphan narcotic antagonists and atropine on analgesia, tremor and hypothermia produced by oxotremorine. ( Ben-Sreti, MM; Sewell, RD; Upton, N, 1982)
"The role of peripheral catecholamines in mediating the pressor and tremorigenic effects of oxotremorine were investigated in conscious rats."3.66Peripheral catecholamines mediate certain responses to central cholinergic receptor stimulation by oxotremorine. ( Kopin, IJ; Weinstock, M; Zavadil, AP, 1980)
"In experiments on cats cold tremor and tremor induced by oxotremorine injection into the caudate nucleus (caudate tremor) were compared."3.66[Comparative neurophysiologic characteristics of cold and caudate tremor]. ( Lupandin, IuV, 1981)
"Oxotremorine, 0."3.66The role of peripheral catecholamines in oxotremorine tremor in the rat and its antagonism by beta adrenoceptor blocking agents. ( Chiueh, CC; Kopin, IJ; Rosin, AJ; Weinstock, M; Zavadil, AP, 1978)
"Fourteen di- and tripeptide analogues of MIF, Pro-Leu-Gly-NH2, have been synthesized and assayed for inhibition of oxotremorine-induced tremor."3.66Tripeptide analogues of melanocyte-stimulating hormone release-inhibiting hormone (Pro-Leu-Gly-NH2) as inhibitors of oxotremorine-induced tremor. ( Björkman, S; Castensson, S; Sievertsson, H, 1979)
"The stereoisomers of some analogues of oxotremorine containing two chiral centres, one in the 1-position of the butynyl chas are oxotremorine antagonists."3.66Stereoselectivity of some oxotremorine antagonists containing two chiral centres. ( Dahlbom, R; Resul, B; Ringdahl, B, 1979)
" The tremorigenic effect of oxotremorine was also measured in mice treated with 10 mg/kg of AT for 1 month."3.66Central cholinergic receptor supersensitivity after long-term atropine administration. ( Herman, ZS; Słominska-Zurek, J, 1979)
"Meperidine (20 and 40 mg/kg, IP) did not block the cholinergic effects (tremor, salivation, and tearing) produced by oxotremorine (0."3.66Meperidine does not block the cholinergic effects of oxotremorine. ( Leander, JD, 1979)
"Oxotremorine, a specific stimulant of central muscarinic acetylcholine receptors, inhibited lateral hypothalamic self-stimulation at a dose-level less than one-tenth of that necessary to produce body tremor."3.66Central cholinergic mechanisms in electrical self-stimulation and in drug-induced tremor in rats. ( Herberg, LJ; Wishart, TB, 1979)
"Administration of oxotremorine to mice produced centrally-mediated effects, such as catalepsy and tremor, and peripheral muscarinic actions, such as diarrhoea and lachrymation."3.66Amantadine antagonism of oxotremorine effects. ( Eshel, Y; Korczyn, AD, 1979)
"Tubocurarine tremor and shivering show identical topography in different muscle groups and identical frequency patterns of the EMG."3.66[Comparative characteristics of mechanisms regulating tubocurarine and cold tremor]. ( Burachevskaia, LE; Lupandin, IuV, 1978)
"The beta-adrenoceptor blockers propranolol, PhQA33 and LB-46 exhibited appreciable activity against tremorine-(TMN) and oxotremorine-(OTMN) induced tremor, whereas pronethalol, (+)-H56/28, (-)-H56/28, Kö-592 and L(+)-INPEA possessed weak action."3.65Tremorine-oxotremorine-induced tremor, hypothermia and analgesia, and physostigmine toxicity, in mice after pretreatment with beta-adrenoceptor antagonists. ( Barar, FS; Madan, BR, 1976)
"5-25 mg/kg) were found to restore and to intensify the oxotremorine-induced tremor in mice when injected i."3.65Thyrotropin releasing hormone (TRH): restoration of oxotremorine tremor in mice. Comparison with quipazine, a serotoninergic and dopaminergic stimulant. ( Kruse, H, 1976)
"Pro-Leu-Gly-NH2 (MIF) inhibits the tremor induced by oxotremorine."3.65On the optimal dosage of Pro-Leu-Gly-NH2 (MIF) in neuropharmacological tests and clinical use. ( Björkman, S; Sievertsson, H, 1977)
"Two oxotremorine antagonists have been examined using oxotremorine as the tremor salivation inducer and the ratios between the central and peripheral nervous systems determined."3.65The central and peripheral effectiveness of two oxotremorine-antagonists determined using oxotremorine-induced tremor and salivation. ( Eicholzer, A; Ogren, SO, 1977)
"Oxotremorine did not alter the level of 5-HT and 5-hydroxyindoleacetic acid in different brain regions."3.65Serotonin content in the central nervous system of rats and cholinergic tremor. ( Funk, KF; Oelszner, W; Staib, AH; Westermann, KH, 1975)
"Cyclic GMP levels were dose-dependently increased by excitatory drugs such as picrotoxin, pentetrazol, oxotremorine and harmaline in mouse cerebellum and medial forebrain (parts of the cortex, hippocampus, hypothalamus, thalamus, striatum and midbrain) in vivo."3.65Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain. ( Dinnedahl, V; Gumulka, SW; Opmeer, FA; Schönhöfer, PS, 1976)
"N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON 954) causes a reproducible rest tremor in mice, of rapid onset and short duration with no associated rigidity or akinesia and in the absence of any marked changes in body temperature or accompanying peripheral parasympathomimetic effects."3.65The production of an alternative laboratory model of the Parkinson syndrome using a new benzylimidoylurea derivative LON 954. ( Coward, DM; Doggett, NS, 1977)
"The tremorogenic properties of a series of benzylimidoylurea derivatives are described."3.65The pharmacology of N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride (LON-954) a new tremorogenic agent. ( Coward, DM; Doggett, NS; Sayers, AC, 1977)
" Antagonism of oxotremorine induced tremors in mice by anticholinergics and neuroleptics was also significantly correlated to the corresponding data obtained in the in-vitro tests."3.65Peripheral and central muscarinic receptor affinity of psychotropic drugs. ( Christensen, AV; Fjalland, B; Hyttel, J, 1977)
"Cyclizine was observed to induce generalized chorea in a patient with mild lingual-facial-buccal dyskinesias."3.65Cyclizine-induced chorea. Observations on the influence of cyclizine on dopamine-related movement disorders. ( Klawans, HL; Moskovitz, C, 1977)
" The effect of various agents injected into the cerebral ventricles of the mouse, upon the tremor and hypothermia produced by oxotremorine (0."3.65Modification of oxotremorine tremor and hypothermia by injections of drugs into the cerebral ventricles of the mouse. ( Doggett, NS; O'Farrell, SA, 1976)
"Glycine and GABA administered intraventricularly and intrastriatally were found to inhibit the oxotremorin tremor in rats."3.65[Effect of various amino acids and their antagonists on the cholinergic tremor and acetylcholine release in the CNS of the rat]. ( Oelszner, W; Scherber, A; Staib, AH, 1975)
" The influence of propranolol on the neuromuscular, tremor-producing and muscarinic effects of oxotremorine was examined."3.65Antioxotremorine action of propranolol. ( Ganguly, DK, 1976)
"Oxotremorine tremor has in common with shivering its frequency range (10-28 Hz) and the co-contraction of flexors and extensors."1.29Role of the stretch reflex in oxotremorine tremor. ( Decima, EE, 1996)
"Tremor was evaluated using spectral analytical techniques."1.28Interactions between ethanol and pantothenic acid on tremor and behavior in squirrel monkeys. ( Newland, MC; Rivera-Calimlim, L; Weiss, B, 1992)
"Tremor was assessed by visual observation and by an objective method based on accelerometry."1.27Beta-adrenoceptor agonists do not cause tremor in the conscious rat. ( Almgren, O; Hallberg, H, 1985)
" In dose-response studies, a slight decrease in exploratory activity and initiation of low-level tremors was observed after 0."1.27A new method for quantification of tremors in mice. ( Isom, GE; Johnson, JD; Meisenheimer, TL, 1986)
"Imipramine methiodide is a quaternary derivative of imipramine which does not cross the blood-brain barrier easily."1.27Comparison of imipramine-imipraminium in mice. To elucidate central or peripheral origin of effects of imipramine. ( Frances, H; Simon, P, 1985)

Research

Studies (156)

TimeframeStudies, this research(%)All Research%
pre-1990116 (74.36)18.7374
1990's25 (16.03)18.2507
2000's13 (8.33)29.6817
2010's2 (1.28)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moon, MW1
Chidester, CG1
Heier, RF1
Morris, JK1
Collins, RJ1
Russell, RR1
Francis, JW1
Sage, GP1
Sethy, VH2
Amstutz, R1
Ringdahl, B13
Karlén, B4
Roch, M4
Jenden, DJ8
Bromidge, SM1
Brown, F1
Cassidy, F1
Clark, MS1
Dabbs, S1
Hadley, MS1
Hawkins, J1
Loudon, JM1
Naylor, CB1
Orlek, BS1
Riley, GJ1
Sauerberg, P1
Jeppesen, L1
Olesen, PH1
Rasmussen, T1
Swedberg, MD1
Sheardown, MJ1
Fink-Jensen, A1
Thomsen, C1
Thøgersen, H1
Rimvall, K1
Ward, JS1
Calligaro, DO1
DeLapp, NW1
Bymaster, FP3
Shannon, HE2
Tajima, O1
Egashira, N4
Ohmi, Y1
Fukue, Y1
Mishima, K4
Iwasaki, K5
Fujiwara, M5
Sugiura, Y1
Furukawa, K2
Ding, M1
Arnold, J1
Turner, J1
Ramkumar, V1
Hughes, LF1
Trammell, RA1
Toth, LA1
Yuzurihara, M1
Hattori, N1
Sakakibara, I1
Ishige, A1
Murugaiah, KD1
Ukponmwan, OE1
DECIMA, EE3
HASLETT, WL1
ARCHIBALD, JL1
BEBBINGTON, A1
SHAKESHAFT, D1
RAND, RW1
Wang, N1
Orr-Urtreger, A1
Chapman, J1
Rabinowitz, R1
Korczyn, AD3
Laplante, F1
Nakagawasai, O1
Srivastava, LK1
Quirion, R1
Howell, G1
West, L1
Jenkins, C1
Lineberry, B1
Yokum, D1
Rockhold, R1
Matsumoto, Y3
Fujioka, M1
Matsushita, M1
Shoyama, Y2
Nishimura, R1
Manome, N1
Kurauchi, K1
Nannan, G1
Runmei, Y1
Fusheng, L1
Shoulan, Z1
Guangqing, L1
Miwa, H2
Hama, K1
Kajimoto, Y1
Kondo, T1
Björkman, S4
Lewander, T2
Zetterström, T2
Resul, B6
Muhi-Eldeen, Z2
Dahlbom, R9
Frances, H2
Chermat, R1
Simon, P2
Pong, SF1
Pelosi, SS1
Wessels, FL1
Yu, CN1
Burns, RH1
White, RE1
Anthony, DR1
Ellis, KO1
Wright, GC1
White, RL1
Alkondon, M2
Ray, A2
Sen, P2
Knowles, WD1
Phillips, MI1
Zetler, G1
Rappaport, MS1
Gentry, RT1
Schneider, DR1
Dole, VP1
Martin, JR1
Driscoll, P1
Gentsch, C1
Shinozaki, H2
Hirate, K1
Ishida, M1
Quock, RM2
Lucas, TS2
Tornos, ME1
Sacristán, A1
Ortiz, JA1
Marks, MJ1
O'Connor, MF1
Artman, LD1
Burch, JB1
Collins, AC1
Bizière, K2
Kan, JP2
Souilhac, J1
Muyard, JP1
Roncucci, R1
Kawanishi, K1
Hashimoto, Y1
Kataoka, Y2
Ueki, S1
Ben-Sreti, MM1
Sewell, RD1
Upton, N1
Weinstock, M3
Zavadil, AP2
Kopin, IJ2
Lupandin, IuV2
Bohman, B1
Halaris, A1
Karbowski, M1
Suemaru, K1
Oishi, R2
Gomita, Y1
Iwata, S3
Nomoto, M4
Fukuda, T3
Sánchez, C1
Lembøl, HL1
Almeida, OM1
Santos, R1
Yeşilada, A1
Gökhan, N1
Ozer, I1
Vural, K1
Erol, K1
Takeuchi, H1
Yatsugi, S1
Hatanaka, K1
Nakato, K1
Hattori, H1
Sonoda, R1
Koshiya, K1
Fujii, M1
Yamaguchi, T1
Nickel, B1
Kolasiewicz, W1
Szelenyi, I1
Egawa, T1
Shuto, H1
Kanaya, A1
Matsunaga, K1
Sueyasu, M1
Welsh, JP1
Gomeza, J3
Shannon, H2
Kostenis, E2
Felder, C2
Zhang, L3
Brodkin, J2
Grinberg, A1
Sheng, H1
Wess, J4
Espínola, EB1
Oliveira, MG1
Carlini, EA1
Bymaster, F1
Xia, B1
Deng, C1
Dallanoce, C1
Conti, P1
De Amici, M1
De Micheli, C1
Barocelli, E1
Chiavarini, M1
Ballabeni, V1
Bertoni, S1
Impicciatore, M1
Mitsuda, M1
Nishi, K1
Fuwa, T1
Mizuno, Y1
Carter, PA1
Falcone, JF1
Stengel, PW1
Cohen, ML1
Felder, CC2
Yamada, M1
Lamping, KG1
Duttaroy, A1
Zhang, W1
Cui, Y1
McKinzie, DL1
Deng, CX1
Faraci, FM1
Cunha, GM1
Farias, PA1
Viana, GS1
Barar, FS1
Madan, BR1
Castensson, S3
Lindeke, B4
Sievertsson, H4
Kruse, H1
Eicholzer, A1
Ogren, SO3
Rosin, AJ1
Chiueh, CC1
Leinot, M1
Benoit, J1
Basiez, M1
Meunier, A1
Labrid, C1
Herman, ZS1
Słominska-Zurek, J1
Oelszner, W4
Funk, KF1
Staib, AH4
Westermann, KH2
Bauer, R1
Kuhn, FJ1
Stockhaus, K1
Wick, H1
Simantov, R1
Snyder, SH1
Oster-Granite, ML1
Silvestrini, B1
Lisciani, R1
Mao, CC1
Guidotti, A2
Costa, E2
Biggio, G1
Opmeer, FA1
Gumulka, SW1
Dinnedahl, V1
Schönhöfer, PS1
Coward, DM2
Doggett, NS3
Ljunggren, C1
Leander, JD1
Wishart, TB1
Herberg, LJ1
Eshel, Y2
David, J1
Kaul, CL1
Grewal, RS1
Sayers, AC1
Fjalland, B1
Christensen, AV1
Hyttel, J1
Svensson, U1
Hacksell, U3
Burachevskaia, LE1
Klawans, HL1
Moskovitz, C1
Maayani, S1
Egozi, Y1
Pinchasi, I1
Sokolovsky, M1
Fisher, A1
Gitter, S1
Cohen, S1
O'Farrell, SA1
Scherber, A2
Ganguly, DK1
Newland, MC1
Rivera-Calimlim, L1
Weiss, B1
Sahin, I1
Tuncer, M1
Ilhan, M1
Nilsson, BM1
Vargas, HM1
István, G1
Gyertyán, I1
Gigler, G1
Somogyi, E1
Petöcz, L1
Tasaka, K1
Kamei, C1
Tsujimoto, S1
Yoshida, T1
Aoki, I1
Gerhart, JM1
Hong, JS1
Tilson, HA1
Worms, P1
Steinberg, R1
Terranova, JP1
Perio, A1
Dufour, P1
Billa, JP1
Fabre, J1
Roquebert, J1
Lundkvist, JR1
Katz, ED1
Clement, JG1
Dyck, WR1
Hallberg, H2
Almgren, O2
Nordström, O1
Danielsson, E1
Peterson, LL1
Bartfai, T3
Lorden, JF1
Oltmans, GA1
McKeon, TW1
Lutes, J1
Beales, M1
Koja, T1
Shimizu, T1
Izumi, K1
Engström, C1
Undén, A1
Ladinsky, H1
Consolo, S1
Wagner, GC1
Walsh, SL1
Wachtel, H1
Löschmann, PA1
Pietzuch, P1
Overstreet, DH1
Janowsky, DS1
Gillin, JC1
Shiromani, PJ1
Sutin, EL1
Johnson, JD1
Meisenheimer, TL1
Isom, GE1
Carlsson, S1
Saligaut, C1
Daoust, M1
Chadelaud, M1
Moore, N1
Chretien, P1
Boismare, F1
Stern, P1
Cox, B1
Tha, SJ1
Funk, K1
Sum, CY1
Gumulka, W1
Kostowski, W1
Czlonkowski, A1
Omori, K1
Kojima, T1
Pleul, O1
Vaupel, DB1
Martin, WR1
Green, R1
Leslie, GB1
Hayman, DG1
Ireson, JD1
Smith, S1
Slater, P1
Laborit, H2
Wermuth, CG1
Vallée, E1
Baron, C2
Thuret, F1
Lamothe, C1
Laurent, J2
De Montigny, C1
Lamarre, Y1
Brossi, A1
Pool, W1
Sheppard, H1
Burns, JJ1
Kaiser, A1
Bigler, R1
Bartholini, G1
Pletscher, A1
Rodríguez, R1
Lapin, IP1
Borgman, RJ2
Mcphillips, JJ2
Stitzel, RE2
Goodman, IJ1
Horst, WD1
Pool, WR1
Spiegel, HE1
Windbladh, B1
Van Woert, MH1
Kolla, VE1
Obvintseva, LM1
Baylor, MR1
Mori, J1
Sato, Y1
Oashi, T1
Hitomi, M1
Lindquist, A1
Lindgren, S1
Blair, MR1
Ursillo, RC1
McCulloch, JA1
Jurna, I1
Grossmann, W1
Nell, T1
Plotnikoff, NP1
Kastin, AJ1
Anderson, MS1
Schally, AV1
Pálosi, E1
Szporny, L1

Other Studies

156 other studies available for oxotremorine and Tremor

ArticleYear
Cholinergic activity of acetylenic imidazoles and related compounds.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Acetylene; Animals; Brain; Imidazoles; Mice; Molecular Structure; Muscarinic Antagonists; Oxotremori

1991
Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:12

    Topics: Abdominal Muscles; Animals; Atropine; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum;

1985
Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Analgesia; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Kinetics; Magn

1988
Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Alzheimer Disease; Animals; Binding Sites; Blood Pressure; Brain; CHO Cells; Cricetinae; Electroence

1997
Muscarinic agonists with antipsychotic-like activity: structure-activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity.
    Journal of medicinal chemistry, 1998, Oct-22, Volume: 41, Issue:22

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Brain; Dopamine Antagonists; Drug Evaluation, Pre

1998
Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice.
    Behavioural brain research, 2010, Jan-05, Volume: 206, Issue:1

    Topics: Age Factors; Aging; Animals; Body Weight; Brain; Maze Learning; Mice; Mice, Knockout; Motor Skills;

2010
Lack of association of a spontaneous mutation of the Chrm2 gene with behavioral and physiologic phenotypic differences in inbred mice.
    Comparative medicine, 2010, Volume: 60, Issue:4

    Topics: Alleles; Amino Acid Sequence; Analysis of Variance; Animals; Base Sequence; Behavior, Animal; Bindin

2010
Ninjin-yoei-to (Ren-Shen-Yang-Rong-Tang) and Polygalae radix improves scopolamine-induced impairment of passive avoidance response in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2003, Volume: 10, Issue:6-7

    Topics: Administration, Oral; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drugs, Chinese He

2003
Functional reactivity of central cholinergic systems following desipramine treatments and sleep deprivation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Analgesia; Animals; Body Temperature; Central Nervous System; Desipram

2003
EFFECTS OF OXOTREMORINE ON GAMMA FIBER ACTIVITY.
    Proceedings of the Western Pharmacology Society, 1964, Volume: 7

    Topics: Cats; Central Nervous System; Chlorpromazine; Decerebrate State; Muscles; Neurophysiology; Oxotremor

1964
IMPROVED SYNTHESIS OF OXOTREMORINE.
    Journal of medicinal chemistry, 1965, Volume: 8

    Topics: Chemistry, Pharmaceutical; Oxotremorine; Parasympatholytics; Parkinsonian Disorders; Pyrroles; Resea

1965
AN IMPROVED SYNTHESIS OF OXOTREMORINE.
    Journal of medicinal chemistry, 1965, Volume: 8

    Topics: Chemistry, Pharmaceutical; Oxotremorine; Pyrroles; Pyrrolidinones; Research; Tremor

1965
OXOTREMORINE INDUCED TREMOR IN THE DECORTICATED CAT.
    International journal of neuropharmacology, 1965, Volume: 4

    Topics: Atropine; Cats; Cerebral Decortication; Drug Tolerance; Electromyography; Heterocyclic Compounds; Ox

1965
Nicotinic acetylcholine receptor alpha5 subunits modulate oxotremorine-induced salivation and tremor.
    Journal of the neurological sciences, 2004, Jul-15, Volume: 222, Issue:1-2

    Topics: Acetylcholine; Animals; Bradycardia; Defecation; Dose-Response Relationship, Drug; Female; Ganglia,

2004
Alterations in behavioral responses to a cholinergic agonist in post-pubertal rats with neonatal ventral hippocampal lesions: relationship to changes in muscarinic receptor levels.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:6

    Topics: Analgesics; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Body Temperature; Female;

2005
In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine.
    BMC pharmacology, 2005, Aug-18, Volume: 5

    Topics: Animals; Cardiovascular System; Cholinergic Antagonists; Diamines; Histamine H1 Antagonists; Loratad

2005
Low dose citalopram reverses memory impairment and electroconvulsive shock-induced immobilization.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: Animals; Brain Chemistry; Citalopram; Dronabinol; Electroshock; Hallucinogens; Male; Memory Disorder

2006
Kamikihi-to, a Kampo medicine, ameliorates impairment of spatial memory in rats.
    Phytotherapy research : PTR, 2007, Volume: 21, Issue:2

    Topics: Animals; Dronabinol; Drugs, Chinese Herbal; Male; Maze Learning; Medicine, Kampo; Memory; Memory Dis

2007
Effects of AIT-082, a purine derivative, on tremor induced by arecoline or oxotremorine in mice.
    Pharmacology, 2007, Volume: 80, Issue:1

    Topics: Aminobenzoates; Animals; Arecoline; Dose-Response Relationship, Drug; Hypoxanthines; Male; Mice; Mic

2007
Effects of zonisamide on experimental tremors in rats.
    Parkinsonism & related disorders, 2008, Volume: 14, Issue:1

    Topics: Animals; Anticonvulsants; Central Nervous System Stimulants; Cholinesterase Inhibitors; Harmaline; I

2008
MIF (Pro-Leu-Gly-NH2): failure to affect oxotremorine effects in mice and rats as well as fluphenazine catalepsy or amphetamine hyperactivity in rats.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:4

    Topics: Amphetamine; Animals; Catalepsy; Fluphenazine; Humans; Male; Mice; Motor Activity; MSH Release-Inhib

1980
Synthesis and pharmacological properties of N-[4-(1-azetidinyl)-2-butynyl]-2-pyrrolidone, a highly potent oxotremorine-like agent.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:6

    Topics: Animals; Central Nervous System; Hypothermia; Male; Mice; Oxotremorine; Peripheral Nerves; Tremor

1980
Oxotremorine behavioural effects as a screening test in mice.
    Progress in neuro-psychopharmacology, 1980, Volume: 4, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Drug Evaluation, Preclinical; Drug Interactions; Male;

1980
5-phenyl-2-furamidines: a new chemical class of potential antidepressants.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:10

    Topics: Acetylcholine; Amidines; Animals; Antidepressive Agents; Blepharoptosis; Brain; Furans; Guinea Pigs;

1983
Effect of beta-adrenergic blocking agents, with differing ancillary properties on oxotremorine induced tremor in mice.
    Indian journal of experimental biology, 1984, Volume: 22, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Female; Male; Mice; Oxotremorine; Tremor

1984
Neurophysiological and behavioral maturation of cerebellar function studied with tremorogenic drugs.
    Neuropharmacology, 1980, Volume: 19, Issue:8

    Topics: Action Potentials; Aging; Alkaloids; Animals; Animals, Newborn; Cerebellum; Harmaline; Nerve Fibers;

1980
Cholecystokinin octapeptide (CCK-8), ceruletide and analogues of ceruletide: effects on tremors induced by oxotremorine, harmine and ibogaine. A comparison with prolyl-leucylglycine amide (MIF), anti-Parkinsonian drugs and clonazepam.
    Neuropharmacology, 1983, Volume: 22, Issue:6

    Topics: Alkaloids; Animals; Antiparkinson Agents; Benzodiazepinones; Ceruletide; Cholecystokinin; Clonazepam

1983
Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP.
    Life sciences, 1984, Jan-02, Volume: 34, Issue:1

    Topics: Alkaloids; Animals; Cerebellum; Cyclic GMP; Diazepam; Dose-Response Relationship, Drug; Ethanol; Har

1984
Differential response to cholinergic stimulation in psychogenitically selected rat lines.
    Psychopharmacology, 1984, Volume: 83, Issue:3

    Topics: Animals; Body Temperature; Female; Male; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous

1984
[A quantitative analyzing method for drug-induced tremor].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:6

    Topics: Animals; Ethology; Harmaline; Magnetics; Mice; Monitoring, Physiologic; Motor Activity; Oxotremorine

1984
Quantitative analysis of drug-induced tremor in mice.
    Neuroscience research, 1984, Volume: 2, Issue:1-2

    Topics: Alkaloids; Animals; Harmaline; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Oxotremorine; Spe

1984
Potentiation by naloxone of the anti-oxotremorine effect of L-DOPA.
    European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4

    Topics: Animals; Carbidopa; Dose-Response Relationship, Drug; Drug Synergism; Levodopa; Male; Mice; Mice, In

1983
Pharmacological study of oral CDP-choline. Interaction with oxotremorine on the parasympathetic system.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:7A

    Topics: Animals; Body Temperature; Choline; Cytidine Diphosphate Choline; Diarrhea; Drug Interactions; Femal

1983
Chronic scopolamine treatment and brain cholinergic function.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:5

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain Chemistry; Choline O-Acetyltransferase; Female;

1984
Muscarinic activity of some secondary and tertiary amines and quaternary ammonium salts structurally related to oxotremorine.
    European journal of pharmacology, 1983, Mar-04, Volume: 87, Issue:4

    Topics: Amines; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle C

1983
Pharmacological evaluation of minaprine dihydrochloride, a new psychotropic drug.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Catalepsy; Dextroamphetamine; Drug Evaluation; Dru

1982
Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:7

    Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Diazepam; Disease

1981
Stereochemical requirements for central and peripheral muscarinic and antimuscarinic activity of some acetylenic compounds related to oxotremorine.
    British journal of pharmacology, 1982, Volume: 76, Issue:2

    Topics: Acetylene; Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mu

1982
Some observations on the effects of enantiomers of two benzomorphan narcotic antagonists and atropine on analgesia, tremor and hypothermia produced by oxotremorine.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 256, Issue:2

    Topics: Animals; Atropine; Benzomorphans; Body Temperature; Drug Interactions; Male; Mice; Morphinans; Narco

1982
Peripheral catecholamines mediate certain responses to central cholinergic receptor stimulation by oxotremorine.
    Monographs in neural sciences, 1980, Volume: 7

    Topics: Adrenal Medulla; Animals; Blood Pressure; Catecholamines; Epinephrine; Hydroxydopamines; Male; Norep

1980
[Comparative neurophysiologic characteristics of cold and caudate tremor].
    Neirofiziologiia = Neurophysiology, 1981, Volume: 13, Issue:3

    Topics: Animals; Cats; Caudate Nucleus; Cold Temperature; Disease Models, Animal; Motor Neurons; Oxotremorin

1981
Effects of tricyclic antidepressants on muscarinic cholinergic receptor binding in mouse brain.
    Life sciences, 1981, Aug-24, Volume: 29, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Male; Mice; Oxotremorine; Quinuclidinyl Benzilate;

1981
Characteristics of tail-tremor induced by nicotine in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:2

    Topics: Animals; Haloperidol; Hexamethonium; Male; Mecamylamine; Motor Activity; Nicotine; Oxotremorine; Rat

1994
Effects of beta-adrenergic blockers on drug-induced tremors.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Fourier Analysis; Harmaline; Male; Mice; Mice, Inbred Strains;

1993
The involvement of muscarinic receptor subtypes in the mediation of hypothermia, tremor, and salivation in male mice.
    Pharmacology & toxicology, 1994, Volume: 74, Issue:1

    Topics: Animals; Female; Guinea Pigs; Hypothermia; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists;

1994
Triiodothyronine (T3) modifies cholinergic-induced hypothermia and tremor in rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3

    Topics: Acetylcholinesterase; Animals; Brain; Hyperthyroidism; Hypothermia; Male; Oxotremorine; Parasympatho

1993
Role of the stretch reflex in oxotremorine tremor.
    Life sciences, 1996, Volume: 58, Issue:22

    Topics: Animals; Cats; Denervation; Electromyography; Female; Male; Muscles; Neurons, Afferent; Oxotremorine

1996
Effect of nipradilol, a beta-adrenergic blocker with vasodilating activity, on oxotremorine-induced tremor in mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1996, Volume: 16, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Male; Mice; Oxotremorine; Propanolamines; Tremor; Vasodilator Age

1996
5-methyl-8-N-substituted-thiocarbamoyl-7,8-diazabicyclo[4.3.0] non-6-enes: evaluation as BSAO inhibitors and pharmacological activity screening.
    Farmaco (Societa chimica italiana : 1989), 1996, Volume: 51, Issue:12

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antiparkinson Agents; Cattle; Female; Imidazole

1996
Pharmacological studies on YM992, a novel antidepressant with selective serotonin re-uptake inhibitory and 5-HT2A receptor antagonistic activity.
    European journal of pharmacology, 1997, Jun-18, Volume: 329, Issue:1

    Topics: Animals; Citalopram; Fluoxetine; Learning; Mice; Mice, Inbred ICR; Morpholines; Olfactory Bulb; Oxot

1997
Quantification of rigidity and tremor activity in rats by using a new device and its validation by different classes of drugs.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:10

    Topics: Analgesics, Opioid; Animals; Antiparkinson Agents; Central Nervous System Depressants; Male; Muscari

1997
Rolipram and its optical isomers, phosphodiesterase 4 inhibitors, attenuated the scopolamine-induced impairments of learning and memory in rats.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:3

    Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Isomerism; Learning; Male; Maze Learn

1997
Enhancement of serotonergic neural activity contributes to cyclosporine-induced tremors in mice.
    European journal of pharmacology, 1998, Jan-02, Volume: 341, Issue:1

    Topics: Animals; Biogenic Monoamines; Brain; Cyclosporine; Hallucinogens; Harmine; Immunosuppressive Agents;

1998
Systemic harmaline blocks associative and motor learning by the actions of the inferior olive.
    The European journal of neuroscience, 1998, Volume: 10, Issue:11

    Topics: Animals; Association Learning; Conditioning, Classical; Female; Harmaline; Learning; Male; Memory; M

1998
Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Feb-16, Volume: 96, Issue:4

    Topics: Analgesia; Animals; Brain; Embryo, Mammalian; Female; Gene Expression; Genomic Library; Homozygote;

1999
Differences in central and peripheral responses to oxotremorine in young and aged rats.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 62, Issue:3

    Topics: Aging; Animals; Central Nervous System; Corpus Striatum; Dacryocystitis; Muscarinic Agonists; Oxotre

1999
Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Aug-31, Volume: 96, Issue:18

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Brain;

1999
Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:8

    Topics: Animals; Atrial Function; Cholinergic Agents; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques;

1999
Effects of beta-blockers and nicardipine on oxotremorine-induced tremor in common marmosets.
    Japanese journal of pharmacology, 1999, Volume: 81, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Callithrix; Flunarizine; Injections,

1999
Differential expression of c-fos following administration of two tremorgenic agents: harmaline and oxotremorine.
    Neuroreport, 2000, Aug-03, Volume: 11, Issue:11

    Topics: Animals; Brain; Cell Count; Dose-Response Relationship, Drug; Harmaline; Male; Neural Pathways; Neur

2000
Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice.
    Life sciences, 2001, Apr-27, Volume: 68, Issue:22-23

    Topics: Animals; Carbachol; Cerebral Cortex; Heart; Heart Rate; Humans; Hypothermia; Male; Mice; Mice, Knock

2001
Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Nov-20, Volume: 98, Issue:24

    Topics: Acetylcholine; Animals; Arteries; Body Temperature; Brain; Cerebral Arteries; Corpus Striatum; Dopam

2001
Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline.
    Behavioural pharmacology, 2002, Volume: 13, Issue:2

    Topics: Acetylcholinesterase; Animals; Anxiety; Avoidance Learning; Hippocampus; Learning Disabilities; Male

2002
Tremorine-oxotremorine-induced tremor, hypothermia and analgesia, and physostigmine toxicity, in mice after pretreatment with beta-adrenoceptor antagonists.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:4

    Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Body Temperature; Depression, Chemical; Male; Mice

1976
Peptides related to melanostatin (Pro-Leu-Gly-NH2) as inhibitors of oxotremorine-induced tremor.
    Acta pharmaceutica Suecica, 1976, Volume: 13, Issue:4

    Topics: Animals; Glycine; Leucine; Male; Mice; MSH Release-Inhibiting Hormone; Oxotremorine; Peptides; Proli

1976
Thyrotropin releasing hormone (TRH): restoration of oxotremorine tremor in mice. Comparison with quipazine, a serotoninergic and dopaminergic stimulant.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 294, Issue:1

    Topics: Animals; Autonomic Agents; Body Temperature; Dopamine; Male; Mice; Neurotransmitter Agents; Oxotremo

1976
On the optimal dosage of Pro-Leu-Gly-NH2 (MIF) in neuropharmacological tests and clinical use.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 298, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Male; Mice; MSH Release-Inhibiting Hormone; Oxotremorine;

1977
The central and peripheral effectiveness of two oxotremorine-antagonists determined using oxotremorine-induced tremor and salivation.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:10

    Topics: Alkynes; Animals; Arecoline; Male; Mice; Oxotremorine; Pyrrolidinones; Salivation; Time Factors; Tre

1977
The role of peripheral catecholamines in oxotremorine tremor in the rat and its antagonism by beta adrenoceptor blocking agents.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:1

    Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Animals; Catecholamines; Epinephrine; Hydroxydopamines

1978
Tripeptide analogues of melanocyte-stimulating hormone release-inhibiting hormone (Pro-Leu-Gly-NH2) as inhibitors of oxotremorine-induced tremor.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:8

    Topics: Animals; Catalepsy; Chemical Phenomena; Chemistry; Fluphenazine; Humans; Male; Mice; Molecular Confo

1979
Stereoselectivity of some oxotremorine antagonists containing two chiral centres.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:12

    Topics: Animals; Atropine; Male; Mice; Molecular Conformation; Mydriatics; Oxotremorine; Stereoisomerism; Tr

1979
[Comparaison, in the mouse, of two treatments for alcohol withdrawal syndrome. Inhibition of oxo tremorine-induced tremor, sedative and motor effects (author's transl)].
    Annales pharmaceutiques francaises, 1979, Volume: 37, Issue:5-6

    Topics: Alcoholism; Animals; Antipsychotic Agents; Barbiturates; Benzamides; Carbamates; Dyskinesia, Drug-In

1979
Central cholinergic receptor supersensitivity after long-term atropine administration.
    Psychopharmacology, 1979, Volume: 64, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Male; Motor Ac

1979
Serotonin content in the central nervous system of rats and cholinergic tremor.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Animals; Brain; Brain Chemistry; Female; Fenclonine; Hydroxyindoleacetic Acid; Oxotremorine; Parasym

1975
[General pharmacology and secretion inhibitory action of (8r)-3alpha-hydroxy-8-isopropyl-1alphaH,5alphaH-tropanium bromide-(+/-)-tropate (ipratropiumbromide) (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:5a

    Topics: Animals; Atropine Derivatives; Blood Pressure; Brain; Cats; Dogs; Ganglia, Autonomic; Gastric Juice;

1976
Harmaline-induced tremor in the rat: abolition by 3-acetylpyridine destruction of cerebellar climbing fibers.
    Brain research, 1976, Sep-10, Volume: 114, Issue:1

    Topics: Alkaloids; Animals; Cerebellar Cortex; Harmaline; Male; Niacinamide; Nicotinic Acids; Oxotremorine;

1976
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice,

1976
Inhibition by diazepam of the tremor and the increase of cerebellar cGMD content elicited by harmaline.
    Brain research, 1975, Jan-17, Volume: 83, Issue:3

    Topics: Alkaloids; Animals; Binding Sites; Cerebellum; Cyclic GMP; Diazepam; Dose-Response Relationship, Dru

1975
3-Acetylpyridine: a tool to inhibit the tremor and the increase of cGMP content in cerebellar cortex elicited by harmaline.
    Brain research, 1975, Oct-10, Volume: 96, Issue:1

    Topics: Alkaloids; Animals; Brain Chemistry; Cerebellar Cortex; Cyclic GMP; Glutamates; Harmaline; Male; Oxo

1975
Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 292, Issue:3

    Topics: Animals; Atropine; Brain; Brain Chemistry; Convulsants; Cyclic AMP; Cyclic GMP; Diazepam; Drug Inter

1976
The production of an alternative laboratory model of the Parkinson syndrome using a new benzylimidoylurea derivative LON 954.
    Psychopharmacology, 1977, Apr-29, Volume: 52, Issue:2

    Topics: Animals; Antiparkinson Agents; Benzimidazoles; Disease Models, Animal; Drug Evaluation, Preclinical;

1977
Acetylene compounds of potential pharmacological value. XXVIII. Oxotremorine analogues substituted with a methyl group in the lactam ring.
    Acta pharmaceutica Suecica, 1979, Volume: 16, Issue:2

    Topics: Acetylene; Animals; Chemical Phenomena; Chemistry; Lactams; Mice; Oxotremorine; Tremor

1979
Meperidine does not block the cholinergic effects of oxotremorine.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:6

    Topics: Animals; Atropine; Female; Meperidine; Oxotremorine; Parasympatholytics; Rats; Salivation; Tears; Tr

1979
Acetylene compounds of potential pharmacological value. XXX. Synthesis and pharmacological properties of N-(4-pyrrolidino-2-pentynyl)-substituted 2-pyrrolidone and succinimide.
    Acta pharmaceutica Suecica, 1979, Volume: 16, Issue:3

    Topics: Acetylene; Animals; Chemical Phenomena; Chemistry; Mice; Oxotremorine; Pyrrolidinones; Succinimides;

1979
Central cholinergic mechanisms in electrical self-stimulation and in drug-induced tremor in rats.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:6

    Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Hyp

1979
Abolition of oxotremorine effects by L-DOPA pretreatment.
    Neuropharmacology, 1979, Volume: 18, Issue:7

    Topics: Animals; Catalepsy; Diarrhea; Dose-Response Relationship, Drug; Drug Interactions; Humans; Levodopa;

1979
Amantadine antagonism of oxotremorine effects.
    Journal of neural transmission, 1979, Volume: 46, Issue:1

    Topics: Amantadine; Animals; Catalepsy; Diarrhea; Drug Antagonism; Humans; Male; Mice; Oxotremorine; Tears;

1979
Pharmacological & biochemical characterization of antiparkinson drugs in reserpinized mice.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:8

    Topics: Animals; Antiparkinson Agents; Ataxia; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Ma

1979
The pharmacology of N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride (LON-954) a new tremorogenic agent.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:12

    Topics: Analgesics; Animals; Cats; Decerebrate State; Dogs; Drug Interactions; Drug Tolerance; Female; Levod

1977
Peripheral and central muscarinic receptor affinity of psychotropic drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 301, Issue:1

    Topics: Acetylcholine; Animals; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle C

1977
Acetylene compounds of potential pharmacological value. XXV. N-(4-pyrrolidino-2-butynyl)-N-alkylcarboxamides.
    Acta pharmaceutica Suecica, 1978, Volume: 15, Issue:1

    Topics: Alkynes; Animals; Drug Evaluation, Preclinical; Mice; Oxotremorine; Parasympathomimetics; Tremor

1978
[Comparative characteristics of mechanisms regulating tubocurarine and cold tremor].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1978, Volume: 64, Issue:10

    Topics: Animals; Body Temperature; Cats; Electric Stimulation; Electromyography; Injections, Intraventricula

1978
Cyclizine-induced chorea. Observations on the influence of cyclizine on dopamine-related movement disorders.
    Journal of the neurological sciences, 1977, Volume: 31, Issue:2

    Topics: Aged; Amphetamine; Animals; Apomorphine; Behavior, Animal; Chorea; Cyclizine; Dyskinesia, Drug-Induc

1977
On the interaction of drugs with the cholinergic nervous system--IV. Tolerance to oxotremorine in mice: in vivo and in vitro studies.
    Biochemical pharmacology, 1977, Sep-15, Volume: 26, Issue:18

    Topics: Animals; Body Temperature; Brain; Drug Tolerance; Female; In Vitro Techniques; Male; Mice; Mice, Inb

1977
A new probe for heterogeneity in muscarinic receptors: 2-methyl-spiro-(1, 3-dioxolane-4, 3')-quinuclidine.
    European journal of pharmacology, 1976, Volume: 37, Issue:2

    Topics: Animals; Blood Pressure; Cricetinae; Depression, Chemical; Ganglia, Spinal; Guinea Pigs; Ileum; In V

1976
Modification of oxotremorine tremor and hypothermia by injections of drugs into the cerebral ventricles of the mouse.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 294, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Atropine; Body Temperature; Dopamine; Drug Interactions; Female

1976
[Effect of various amino acids and their antagonists on the cholinergic tremor and acetylcholine release in the CNS of the rat].
    Acta biologica et medica Germanica, 1975, Volume: 34, Issue:9

    Topics: Acetylcholine; Aminobutyrates; Animals; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine;

1975
Antioxotremorine action of propranolol.
    British journal of pharmacology, 1976, Volume: 56, Issue:1

    Topics: Animals; Blood Pressure; Diaphragm; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction

1976
Interactions between ethanol and pantothenic acid on tremor and behavior in squirrel monkeys.
    Journal of studies on alcohol, 1992, Volume: 53, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Female; Nervous System; Oxotremorine; Pantotheni

1992
Dopamine receptor agonists, N,N-dipropyl-2-aminotetralin (TL-68) and 2-di-n-propylamino-4,7-dimethoxyindane (RDS-127) antagonize oxotremorine-induced tremors by antimuscarinic action in mice.
    Archives internationales de physiologie et de biochimie, 1990, Volume: 98, Issue:1

    Topics: Animals; Atropine; Dopamine Agents; Indans; Indenes; Male; Mice; Naphthalenes; Oxotremorine; Parasym

1990
Phenyl-substituted analogues of oxotremorine as muscarinic antagonists.
    Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

    Topics: Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Magnetic Resonance

1992
Possible involvement of the antiserotoninergic and antihistaminergic activity in the anticataleptogenic effect of EGYT-2509.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Animals; Antipsychotic Agents; Catalepsy; Dibenzoxazepines; Histamine Antagonists; Oxotremorine; Rat

1990
Central effect of the potent long-acting H1-antihistamine levocabastine.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:12

    Topics: Acetates; Animals; Avoidance Learning; Central Nervous System; Electroencephalography; Histamine H1

1990
Studies on the mechanism of chlordecone-induced tremor in rats.
    Neurotoxicology, 1985,Spring, Volume: 6, Issue:1

    Topics: Animals; Apomorphine; Ataxia; Chlordecone; Dose-Response Relationship, Drug; Harmine; Insecticides;

1985
Cholinomimetic activities of minaprine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:4

    Topics: Animals; Atropine; Avoidance Learning; Behavior, Animal; Female; Guinea Pigs; In Vitro Techniques; M

1989
[Evaluation of the central anticholinergic activity of antidepressants. Comparison of two experimental methods].
    Annales pharmaceutiques francaises, 1989, Volume: 47, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Clomipramine; Dibenzazepines; Female; Guinea Pi

1989
Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Mice;

1989
Muscarinic actions and receptor binding of the enantiomers of BM 130, an alkylating analog of oxotremorine.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1

    Topics: Alkylation; Animals; Body Temperature; Cerebral Cortex; Guinea Pigs; Lethal Dose 50; Male; Mice; Oxo

1989
Device for quantitating tremor activity in mice: antitremor activity of atropine versus soman- and oxotremorine-induced tremors.
    Journal of pharmacological methods, 1989, Volume: 22, Issue:1

    Topics: Animals; Atropine; Dose-Response Relationship, Drug; Isometric Contraction; Male; Mice; Oxotremorine

1989
Beta-adrenoceptor agonists do not cause tremor in the conscious rat.
    Acta physiologica Scandinavica, 1985, Volume: 124, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Isoproterenol; Male; Oxotremorine; Rats; Rats, Inbred Strains; Re

1985
Cholinergic involvement in the modulation of oxotremorine-tremor in mice by propranolol.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atropine; Brain; Cholinesterase Inhibitors; Dose-Response Rela

1985
A selective potentiation by naloxone of L-dopa but not atropine suppression of oxotremorine-induced tremor in mice.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:9

    Topics: Animals; Atropine; Drug Synergism; Levodopa; Male; Mice; Mice, Inbred ICR; Naloxone; Oxotremorine; T

1985
Modulation of oxotremorine-induced tremor by central beta-adrenoceptors.
    Acta physiologica Scandinavica, 1987, Volume: 129, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood-Brain Barrier; Epinephrine; Ma

1987
In vivo and in vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker.
    Journal of neural transmission, 1985, Volume: 61, Issue:1-2

    Topics: Alanine; Animals; Brain; Cyclic GMP; Drug Synergism; Hippocampus; Male; Mice; Oxotremorine; Physosti

1985
Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt).
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:10

    Topics: Alkaloids; Animals; Behavior, Animal; Cerebellum; Cyclic GMP; Drug Resistance; Dystonia; Harmaline;

1985
[Power spectral analysis of tremor induced by TRH and oxotremorine in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:2

    Topics: Animals; Atropine; Haloperidol; Male; Mice; Oxotremorine; Propranolol; Reaction Time; Thyrotropin-Re

1986
BM-5, a centrally active partial muscarinic agonist with low tremorogenic activity. In vivo and in vitro studies.
    Psychopharmacology, 1987, Volume: 91, Issue:2

    Topics: Acetylcholine; Animals; Body Temperature; Brain; Choline; Dose-Response Relationship, Drug; In Vitro

1987
Increased sensitivity of mice to tremorogenic agents following MPP+.
    Psychopharmacology, 1987, Volume: 92, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Conditioning, Operant; Corpus Striatum; Drug Synergism; Male;

1987
Absence of anticholinergic activity of rolipram, an antidepressant with a novel mechanism of action, in three different animal models in vivo.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:5

    Topics: Animals; Antidepressive Agents; Body Temperature; Female; Mice; Oxotremorine; Parasympatholytics; Pi

1988
Regional differences in receptor reserve for analogs of oxotremorine in vivo: implications for development of selective muscarinic agonists.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2

    Topics: Analgesia; Animals; Body Temperature; Guinea Pigs; Male; Mice; Mice, Inbred Strains; Muscarine; Oxot

1987
Stress-induced immobility in rats with cholinergic supersensitivity.
    Biological psychiatry, 1986, Volume: 21, Issue:7

    Topics: Amitriptyline; Animals; Arousal; Hippocampus; Kinetics; Male; Motor Activity; Oxotremorine; Quinucli

1986
A new method for quantification of tremors in mice.
    Journal of pharmacological methods, 1986, Volume: 16, Issue:4

    Topics: Animals; Computers; Electric Conductivity; Male; Mice; Oxotremorine; Tremor

1986
Muscarinic actions of an N-methyl-N-2-bromoethylamino analog of oxotremorine (BR 401) in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2

    Topics: Analgesics; Animals; Atropine; Body Temperature Regulation; Male; Mice; Oxotremorine; Parasympathomi

1987
Serotonergic potentiation of muscarinic agonist evoked tremor and salivation in rat and mouse.
    Psychopharmacology, 1985, Volume: 86, Issue:3

    Topics: Alanine; Animals; Arecoline; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Oxo

1985
Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:1

    Topics: Administration, Oral; Animals; Choline; Cytidine Diphosphate Choline; Diarrhea; Female; Hypothermia;

1985
Comparison of imipramine-imipraminium in mice. To elucidate central or peripheral origin of effects of imipramine.
    Neuropharmacology, 1985, Volume: 24, Issue:7

    Topics: Animals; Apomorphine; Body Temperature; Drug Synergism; Imipramine; Male; Mice; Motor Activity; Oxot

1985
The influence of synthetic "substance P" on tremor caused by LSD in mice.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:3

    Topics: Acetylcholine; Amphetamine; Animals; Atropine; Behavior, Animal; Brain Chemistry; Drug Synergism; Fe

1973
Interactions between oxotremorine and inhibitors of cholinesterase enzymes.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:7

    Topics: Animals; Atropine; Body Temperature; Brain; Cholinesterase Inhibitors; Drug Synergism; Female; Isofl

1973
[Tremor and motility following oxotremorine and harmine in rats with lesions of the nigro-striatal system].
    Acta biologica et medica Germanica, 1974, Volume: 33, Issue:1

    Topics: Alkaloids; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Female; Globus Pallidus; Heterocycli

1974
Studies on the inhibition of oxotremorine induced tremor by a melanocyte-stimulating hormone release-inhibiting factor, thyrotropin releasing hormone and related peptides.
    FEBS letters, 1974, Aug-15, Volume: 44, Issue:1

    Topics: Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamates; Glycine; Histidin

1974
Role of 5-HT in the action of some drugs affecting extrapyramidal system.
    Pharmacology, 1973, Volume: 10, Issue:6

    Topics: Amphetamine; Animals; Brain; Catalepsy; Chlorpromazine; Electrodes; Extrapyramidal Tracts; Female; F

1973
Effect of L-5HTP on tremorine- or oxotremorine-induced tremor in mice and rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Drug Synergism; Fenclonine; Male; Mice; Oxotremorine; Rats;

1973
Proceedings: On the action of oxotremorine on the cholinergic system of rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Acetylcholine; Acetyltransferases; Animals; Brain; Brain Stem; Cerebral Cortex; Choline; Cholinester

1974
Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.
    Psychopharmacologia, 1973, Volume: 30, Issue:1

    Topics: Animals; Atropine; Chlorpromazine; Cyproheptadine; Dogs; Drug Interactions; Imipramine; Oxotremorine

1973
Synthesis and pharmacology of 1-(2-thioxopyrrolidino)-4-pyrrolidino-2-butyne, the thiolactam analogue of oxotremorine.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:1

    Topics: Acetylcholine; Alkynes; Animals; Chromatography, Gas; Chromatography, Thin Layer; Guinea Pigs; Ileum

1972
The effects of some beta adrenergic blocking agents on the central and peripheral actions of tremorine and oxotremorine.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 197, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Atropine; Central Nervous System;

1972
[Motor reactions of chronic spinal rats after administration of oxotremorine].
    Acta biologica et medica Germanica, 1974, Volume: 32, Issue:2-3

    Topics: Animals; Behavior, Animal; Decerebrate State; Forelimb; Motor Activity; Oxotremorine; Rats; Spine; T

1974
Effect of 6-hydroxydopamine on some actions of tremorine and oxotremorine.
    European journal of pharmacology, 1974, Volume: 25, Issue:2

    Topics: Amines; Animals; Body Temperature; Brain Chemistry; Catecholamines; Dopamine; Dose-Response Relation

1974
[Pharmacological study of ethyl gamma hydroxybutyrate glycolate].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1974, Volume: 15, Issue:1

    Topics: Animals; Cerebral Cortex; Dopamine; Glycolates; Hydroxybutyrates; Hypnotics and Sedatives; Male; Mic

1974
Activity in the olivo-cerebello-bulbar system of the cat during ibogaline- and oxotremorine-induced tremor.
    Brain research, 1974, Dec-27, Volume: 82, Issue:2

    Topics: Animals; Brain Stem; Cats; Cerebellar Nuclei; Electroencephalography; Indole Alkaloids; Indoles; Liv

1974
L-DOPA: chemical modifications and biological evaluation.
    Advances in neurology, 1974, Volume: 5

    Topics: Animals; Antiparkinson Agents; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Hypothermi

1974
Antagonism of tremorine-induced tremor by serotoninergic agents in mice. Interactions with levodopa.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jun-01, Volume: 11, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Benztropine; Dihydroxyphenylalanine; Dose-Response Relations

1972
[Inhibition by (intraventricular) glycine of the tremorigenic activity of oxotremorine in the rabbit].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1974, Volume: 15, Issue:1

    Topics: Animals; Brain; Caudate Nucleus; Cerebral Ventricles; Corpus Striatum; Glycine; Injections; Male; Ox

1974
Interaction of kynurenine and its metabolites with tryptamine, serotonin and its precursors and oxotremorine.
    Psychopharmacologia, 1972, Volume: 26, Issue:3

    Topics: Animals; Behavior, Animal; Diarrhea; Drug Antagonism; Drug Interactions; Female; Humans; Hypothermia

1972
Synthesis and pharmacology of centrally acting dopamine derivatives qnd analogs in relation to parkinson's disease.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:6

    Topics: Acetylation; Alkylation; Animals; Body Temperature; Chemical Phenomena; Chemistry; Dopamine; Hydroly

1973
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
    European journal of pharmacology, 1973, Volume: 21, Issue:3

    Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain;

1973
Postnatal development of central effects of atropine and oxotremorine in dogs in relation to brain development.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:1

    Topics: Acetyltransferases; Age Factors; Animals; Atropine; Behavior, Animal; Brain; Brain Chemistry; Cholin

1973
Antimuscarinic drugs--effect on brain acetylcholine and tremors in rats.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Acetylcholine; Animals; Atropine; Benztropine; Brain Chemistry; Depression, Chemical; Drug Interacti

1973
[Tremorine as test for evaluating antitremor agents (a review of the literature)].
    Farmakologiia i toksikologiia, 1973, Volume: 36, Issue:5

    Topics: Animals; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Guinea P

1973
Alpha-methyldopamine derivatives. Synthesis and pharmacology.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:4

    Topics: Animals; Apomorphine; Blepharoptosis; Body Temperature; Depression, Chemical; Dihydroxyphenylalanine

1974
[Pharmacological study of amantadine, a new antiparkinson drug].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:1

    Topics: Amantadine; Amines; Animals; Antiparkinson Agents; Avoidance Learning; Brain; Catatonia; Dopamine; D

1974
Acetylene compounds of potential pharmacological value. XVI. N-(perhydroazepinoalkynyl)- and N-(perhydroazocinoalkynyl)succinimides.
    Acta pharmaceutica Suecica, 1972, Volume: 9, Issue:2

    Topics: Acetylcholine; Animals; Crystallization; Eye; Guinea Pigs; Ileum; In Vitro Techniques; Mice; Oxotrem

1972
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 197, Issue:1

    Topics: Alkaloids; Animals; Antiparkinson Agents; Atropine; Benztropine; Body Temperature; Central Nervous S

1972
Depression by amantadine of drug-induced rigidity in the rat.
    Neuropharmacology, 1972, Volume: 11, Issue:4

    Topics: Amantadine; Animals; Depression, Chemical; Electrodes, Implanted; Electromyography; Motor Activity;

1972
Oxotremorine antagonism by a hypothalamic hormone, melanocyte-stimulating hormone release-inhibiting factor (MIF).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:3

    Topics: Acetylcholine; Animals; Ataxia; Diarrhea; Dihydroxyphenylalanine; Drug Antagonism; Guinea Pigs; Huma

1972
Effect of gamma-hydroxybutyric acid on tremor induced oxotremorin.
    Activitas nervosa superior, 1972, Volume: 14, Issue:4

    Topics: Animals; Atropine; Brain Chemistry; Disease Models, Animal; Drug Antagonism; Drug Synergism; Female;

1972