oxotremorine has been researched along with Pituitary Neoplasms in 7 studies
Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Moreover, PDBu, which causes attenuation of the maximal response to vasoactive intestinal polypeptide (VIP), also induced a small right shift in the dose-response curve for VIP-induced cyclic AMP accumulation." | 1.28 | Regulation of GH3 pituitary tumour-cell adenylate cyclase activity by activators of protein kinase C. ( Brown, BL; Dobson, PR; Quilliam, LA, 1989) |
| "Pretreatment with oxotremorine also reduced the density of muscarinic receptors without affecting the affinity of these sites for [3H]quinuclidinyl benzilate." | 1.27 | Muscarinic cholinergic receptors in mouse pituitary tumor cells: prolonged agonist pretreatment decreases receptor content and increases forskolin- and hormone-stimulated cyclic AMP synthesis and adrenocorticotropin secretion. ( Desjardins, D; Heisler, S; Nguyen, MH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, BL | 4 |
| Wojcikiewicz, RJ | 3 |
| Dobson, PR | 4 |
| Robinson, A | 2 |
| Irons, LI | 2 |
| Heisler, S | 3 |
| Veilleux, R | 1 |
| Labrie, F | 1 |
| Quilliam, LA | 1 |
| Desjardins, D | 1 |
| Nguyen, MH | 1 |
7 other studies available for oxotremorine and Pituitary Neoplasms
| Article | Year |
|---|---|
Pertussis toxin blocks the inhibitory effect of muscarinic cholinergic agonists on cyclic AMP accumulation and prolactin secretion in GH3 anterior-pituitary tumour cells.
Topics: Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Cell Line; Cyclic AMP; Oxotremorine; Parasympath | 1984 |
PHI stimulates ACTH release from pituitary tumor cell.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Calcium; Cell Line; Corticotropin | 1984 |
Muscarinic acetylcholine receptor activation causes inhibition of cyclic AMP accumulation, prolactin and growth hormone secretion in GH3 rat anterior pituitary tumour cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Carbachol; Cell Line; Cyclic AMP; Growth Hormon | 1984 |
The relationship between pertussis-toxin-induced ADP-ribosylation of a plasma-membrane protein and reversal of muscarinic inhibition of prolactin secretion in GH3 cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Autoradiography; Bacterial Toxins; C | 1984 |
Regulation of GH3 pituitary tumour-cell adenylate cyclase activity by activators of protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bombesin; Cholera Toxin; Colforsin; Cyclic AMP; Dose | 1989 |
Muscarinic cholinergic receptors in mouse pituitary tumor cells: prolonged agonist pretreatment decreases receptor content and increases forskolin- and hormone-stimulated cyclic AMP synthesis and adrenocorticotropin secretion.
Topics: Adrenocorticotropic Hormone; Animals; Cell Line; Colforsin; Cyclic AMP; Cycloheximide; Diterpenes; H | 1985 |
Inhibition of ACTH secretion in mouse pituitary tumor cells by activation of muscarinic cholinergic receptors.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Carbachol; Cells, Cultured; Cyclic AMP; Iso | 1985 |