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oxotremorine and Parkinsonian Disorders

oxotremorine has been researched along with Parkinsonian Disorders in 3 studies

Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.

Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Research Excerpts

ExcerptRelevanceReference
" Assessment of the effects of chronic administration of Diol (20mg/kg) and L-DOPA to animals with 6-OHDA-induced PS showed that administration of Diol alleviated the symptoms of sensorimotor deficit in right limbs in rats."1.46Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models. ( Ardashov, O; Ivanova, Е; Kapitsa, I; Khazanov, V; Salakhutdinov, N; Valdman, E; Volcho, K; Voronina, TI, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valdman, E1
Kapitsa, I1
Ivanova, Е1
Voronina, TI1
Ardashov, O1
Volcho, K1
Khazanov, V1
Salakhutdinov, N1
ARCHIBALD, JL1
Hegab, MI1
Abdulla, MM1

Other Studies

3 other studies available for oxotremorine and Parkinsonian Disorders

ArticleYear
Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models.
    European journal of pharmacology, 2017, Nov-15, Volume: 815

    Topics: Animals; Antiparkinson Agents; Catalepsy; Cyclohexanols; Disease Models, Animal; Male; Mice; Mice, I

2017
IMPROVED SYNTHESIS OF OXOTREMORINE.
    Journal of medicinal chemistry, 1965, Volume: 8

    Topics: Chemistry, Pharmaceutical; Oxotremorine; Parasympatholytics; Parkinsonian Disorders; Pyrroles; Resea

1965
4-Chloro-2,2-disubstituted chromen-3-carboxaldehyde: synthesis of some fused polycyclic heterocycles as anti-inflammatory, analgesic, anticonvulsant, and antiparkinsonian agents.
    Archiv der Pharmazie, 2006, Volume: 339, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antiparkinson Agents; Benzopyrans; C

2006