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oxotremorine and Glioma

oxotremorine has been researched along with Glioma in 6 studies

Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Glioma C62B cells were incubated for 18 h with [1-14C]arachidonic acid."7.67Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells. ( DeGeorge, JJ; Lapetina, EG; McCarthy, KD; Morell, P, 1986)
" Incubation of SH-SY5Y neuroblastoma cells with oxotremorine-M resulted in a time-dependent endocytosis of both muscarinic receptors and alpha subunits of G0 and G11, but not of isoforms of phosphoinositide-specific phospholipase C, into a subfraction of smooth endoplasmic reticulum (V1)."3.69Agonist-induced endocytosis of muscarinic cholinergic receptors: relationship to stimulated phosphoinositide turnover. ( Fisher, SK; Linseman, DA; McEwen, EL; Sorensen, SD, 1997)
"Glioma C62B cells were incubated for 18 h with [1-14C]arachidonic acid."3.67Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells. ( DeGeorge, JJ; Lapetina, EG; McCarthy, KD; Morell, P, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, MM1
Harden, TK1
Graeser, D1
Neubig, RR1
Ammer, H1
Schulz, R1
Sorensen, SD1
McEwen, EL1
Linseman, DA1
Fisher, SK1
Caulfield, MP1
DeGeorge, JJ1
Morell, P1
McCarthy, KD1
Lapetina, EG1

Other Studies

6 other studies available for oxotremorine and Glioma

ArticleYear
Modification of receptor-mediated inhibition of adenylate cyclase in NG108-15 neuroblastoma X glioma cells by n-ethylmaleimide.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Epinephrine; Ethylmaleimide; Glioma; GTP-Binding Pr

1984
Compartmentation of receptors and guanine nucleotide-binding proteins in NG108-15 cells: lack of cross-talk in agonist binding among the alpha 2-adrenergic, muscarinic, and opiate receptors.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Cell Compartmentation; Enkephalin, D-Penicillamin

1993
Chronic exposure of NG 108-15 cells to inhibitory acting drugs reduces stimulatory prostaglandin E1 receptor number.
    European journal of pharmacology, 1996, Apr-29, Volume: 302, Issue:1-3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Animals; Binding

1996
Agonist-induced endocytosis of muscarinic cholinergic receptors: relationship to stimulated phosphoinositide turnover.
    Journal of neurochemistry, 1997, Volume: 68, Issue:4

    Topics: Blotting, Western; Diglycerides; Endocytosis; Glioma; Humans; Isoenzymes; Lipid Metabolism; Muscarin

1997
Muscarinic receptor-mediated inhibition of voltage-activated Ca current in neuroblastoma x glioma hybrid (NG 108-15) cells--reduction of muscarinic agonist and antagonist potency by tetraethylammonium (TEA).
    Neuroscience letters, 1991, Jun-24, Volume: 127, Issue:2

    Topics: Acetylcholine; Action Potentials; Atropine; Calcium; Glioma; Humans; Hybridization, Genetic; Neurobl

1991
Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells.
    The Journal of biological chemistry, 1986, Mar-05, Volume: 261, Issue:7

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Calcimycin; Carbachol; Cell L

1986