oxotremorine has been researched along with Disease Models, Animal in 35 studies
Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oxotremorine is a cholinergic agonist known to induce acute hypothermia." | 7.74 | Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats. ( Grauer, E; Levy, A, 2007) |
| "Levetiracetam (LEV) is a new antiepileptic drug effective as adjunctive therapy for partial seizures." | 7.73 | Evaluation of levetiracetam effects on pilocarpine-induced seizures: cholinergic muscarinic system involvement. ( Aguiar, LM; Fonteles, MM; Freitas, RM; Nascimento, VS; Nogueira, CR; Oliveira, AA; Sousa, FC; Viana, GS, 2005) |
| "Harmine, a hallucinogen with potent monoamine oxidase inhibitory properties, induced abnormal behavior, including tremor, scratching, head twitch and cage biting, in the mouse." | 7.66 | Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. ( Fujiwara, M; Hashimoto, Y; Kataoka, Y; Kawanishi, K; Ueki, S, 1981) |
| "We measured [(3)H]AF-DX 384 binding in BA 46 and BA 24 from subjects with bipolar disorders (n = 14), major depressive disorders (n = 19), as well as age- and sex-matched controls (n = 19) and the CNS of rats treated with fluoxetine or imipramine." | 3.83 | Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants. ( Dean, B; Gibbons, AS; Jeon, WJ; Scarr, E, 2016) |
| " Oxotremorine is a cholinergic agonist known to induce acute hypothermia." | 3.74 | Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats. ( Grauer, E; Levy, A, 2007) |
| "Levetiracetam (LEV) is a new antiepileptic drug effective as adjunctive therapy for partial seizures." | 3.73 | Evaluation of levetiracetam effects on pilocarpine-induced seizures: cholinergic muscarinic system involvement. ( Aguiar, LM; Fonteles, MM; Freitas, RM; Nascimento, VS; Nogueira, CR; Oliveira, AA; Sousa, FC; Viana, GS, 2005) |
| "Neonatal treatment with clomipramine induces behavioral alterations during adulthood that resemble symptoms observed in human depression." | 3.70 | Pharmacological features of masculine sexual behavior in an animal model of depression. ( Bonilla-Jaime, H; Retana-Marquez, S; Velazquez-Moctezuma, J, 1998) |
| "Harmine, a hallucinogen with potent monoamine oxidase inhibitory properties, induced abnormal behavior, including tremor, scratching, head twitch and cage biting, in the mouse." | 3.66 | Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. ( Fujiwara, M; Hashimoto, Y; Kataoka, Y; Kawanishi, K; Ueki, S, 1981) |
| "In experiments on cats cold tremor and tremor induced by oxotremorine injection into the caudate nucleus (caudate tremor) were compared." | 3.66 | [Comparative neurophysiologic characteristics of cold and caudate tremor]. ( Lupandin, IuV, 1981) |
| "N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON 954) causes a reproducible rest tremor in mice, of rapid onset and short duration with no associated rigidity or akinesia and in the absence of any marked changes in body temperature or accompanying peripheral parasympathomimetic effects." | 3.65 | The production of an alternative laboratory model of the Parkinson syndrome using a new benzylimidoylurea derivative LON 954. ( Coward, DM; Doggett, NS, 1977) |
| " Assessment of the effects of chronic administration of Diol (20mg/kg) and L-DOPA to animals with 6-OHDA-induced PS showed that administration of Diol alleviated the symptoms of sensorimotor deficit in right limbs in rats." | 1.46 | Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models. ( Ardashov, O; Ivanova, Е; Kapitsa, I; Khazanov, V; Salakhutdinov, N; Valdman, E; Volcho, K; Voronina, TI, 2017) |
| "Transient focal cerebral ischemia was produced for 2 hrs with the intravascular suture technique." | 1.31 | Oxotremorine-induced cerebral hyperemia does not predict infarction volume in spontaneously hypertensive or stroke-prone rats. ( Bhardwaj, A; Harukuni, I; Kirsch, JR; Takahashi, H; Traystman, RJ, 2000) |
| " Nicotine enhanced release, with a bell-shaped dose-response curve." | 1.29 | Lesion with the neurotoxin AF64A alters hippocampal cholinergic receptor function. ( Potter, PE; Thorne, B, 1995) |
| "Treatment with haloperidol (0." | 1.28 | Drug-induced purposeless chewing: animal model of dyskinesia or nausea? ( Iversen, SD; Rupniak, NM; Tye, SJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (31.43) | 18.7374 |
| 1990's | 13 (37.14) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 5 (14.29) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Valdman, E | 1 |
| Kapitsa, I | 1 |
| Ivanova, Е | 1 |
| Voronina, TI | 1 |
| Ardashov, O | 1 |
| Volcho, K | 1 |
| Khazanov, V | 1 |
| Salakhutdinov, N | 1 |
| Yankelevitch-Yahav, R | 1 |
| Roni, YY | 1 |
| Joel, D | 1 |
| Daphna, J | 1 |
| Gibbons, AS | 1 |
| Jeon, WJ | 1 |
| Scarr, E | 1 |
| Dean, B | 1 |
| Pak, KJ | 1 |
| Ostrom, RS | 1 |
| Matsui, M | 1 |
| Ehlert, FJ | 1 |
| Oliveira, AA | 1 |
| Nogueira, CR | 1 |
| Nascimento, VS | 1 |
| Aguiar, LM | 1 |
| Freitas, RM | 1 |
| Sousa, FC | 1 |
| Viana, GS | 1 |
| Fonteles, MM | 1 |
| Grauer, E | 1 |
| Levy, A | 1 |
| Kawanishi, K | 1 |
| Hashimoto, Y | 1 |
| Fujiwara, M | 1 |
| Kataoka, Y | 1 |
| Ueki, S | 2 |
| Kehr, W | 1 |
| Lupandin, IuV | 1 |
| Orpen, G | 1 |
| Steiner, M | 1 |
| Thorne, B | 1 |
| Potter, PE | 1 |
| Kinoshita, H | 1 |
| Hasegawa, T | 1 |
| Katsumata, Y | 1 |
| Kameyama, T | 1 |
| Yamamoto, I | 1 |
| Nabeshima, T | 1 |
| Overstreet, DH | 5 |
| Janowsky, DS | 2 |
| Pucilowski, O | 1 |
| Rezvani, AH | 1 |
| Kryzhanovskiĭ, GN | 1 |
| Atadzhanov, MA | 1 |
| Voronina, TA | 1 |
| Nerobkova, LN | 1 |
| Hall, ED | 1 |
| Andrus, PK | 1 |
| Pazara, KE | 1 |
| Plate, R | 1 |
| Plaum, MJ | 1 |
| de Boer, T | 1 |
| Andrews, JS | 1 |
| Rae, DR | 1 |
| Gibson, S | 1 |
| Daws, LC | 3 |
| Schiller, GD | 3 |
| Orbach, J | 2 |
| Bonilla-Jaime, H | 1 |
| Retana-Marquez, S | 1 |
| Velazquez-Moctezuma, J | 1 |
| Harukuni, I | 1 |
| Takahashi, H | 1 |
| Traystman, RJ | 1 |
| Bhardwaj, A | 1 |
| Kirsch, JR | 1 |
| Abrahám, G | 1 |
| Sólyom, S | 1 |
| Csuzdi, E | 1 |
| Berzsenyi, P | 1 |
| Ling, I | 1 |
| Tarnawa, I | 1 |
| Hámori, T | 1 |
| Pallagi, I | 1 |
| Horváth, K | 1 |
| Andrási, F | 1 |
| Kapus, G | 1 |
| Hársing, LG | 1 |
| Király, I | 1 |
| Patthy, M | 1 |
| Horváth, G | 1 |
| Felder, CC | 1 |
| Porter, AC | 1 |
| Skillman, TL | 1 |
| Zhang, L | 1 |
| Bymaster, FP | 1 |
| Nathanson, NM | 1 |
| Hamilton, SE | 1 |
| Gomeza, J | 1 |
| Wess, J | 1 |
| McKinzie, DL | 1 |
| Coward, DM | 1 |
| Doggett, NS | 1 |
| David, J | 1 |
| Kaul, CL | 1 |
| Grewal, RS | 1 |
| Santucci, AC | 1 |
| Haroutunian, V | 1 |
| Davis, KL | 1 |
| Rupniak, NM | 1 |
| Tye, SJ | 1 |
| Iversen, SD | 1 |
| Double, K | 1 |
| Okamoto, E | 1 |
| Kuwata, K | 1 |
| Toyosaka, A | 1 |
| Nagai, K | 1 |
| Brossi, A | 1 |
| Pool, W | 1 |
| Sheppard, H | 1 |
| Burns, JJ | 1 |
| Kaiser, A | 1 |
| Bigler, R | 1 |
| Bartholini, G | 1 |
| Pletscher, A | 1 |
| Horst, WD | 1 |
| Pool, WR | 1 |
| Spiegel, HE | 1 |
| Kolla, VE | 1 |
| Obvintseva, LM | 1 |
| Pálosi, E | 1 |
| Szporny, L | 1 |
35 other studies available for oxotremorine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models.
Topics: Animals; Antiparkinson Agents; Catalepsy; Cyclohexanols; Disease Models, Animal; Male; Mice; Mice, I | 2017 |
The role of the cholinergic system in the signal attenuation rat model of obsessive-compulsive disorder.
Topics: Acetylcholine; Animals; Behavior, Animal; Compulsive Behavior; Conditioning, Operant; Disease Models | 2013 |
Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Depressive Diso | 2016 |
Impaired M3 and enhanced M2 muscarinic receptor contractile function in a streptozotocin model of mouse diabetic urinary bladder.
Topics: Animals; Colforsin; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mice; Mice, Inbre | 2010 |
Evaluation of levetiracetam effects on pilocarpine-induced seizures: cholinergic muscarinic system involvement.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Hippocampus; Levetiracetam; Male; Mic | 2005 |
Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats.
Topics: Aldicarb; Animals; Body Temperature; Carbamates; Central Nervous System; Cholinesterase Inhibitors; | 2007 |
Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice.
Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Diazepam; Disease | 1981 |
[Drug therapy of Parkinson disease and parkinson disease-like symptoms].
Topics: Adenylyl Cyclases; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biperiden; Brain; Catechol O-Methy | 1981 |
[Comparative neurophysiologic characteristics of cold and caudate tremor].
Topics: Animals; Cats; Caudate Nucleus; Cold Temperature; Disease Models, Animal; Motor Neurons; Oxotremorin | 1981 |
The WAGxDA rat: an animal model of cholinergic supersensitivity.
Topics: Animals; Autonomic Nervous System Diseases; Behavior, Animal; Body Temperature; Brain Chemistry; Dis | 1995 |
Lesion with the neurotoxin AF64A alters hippocampal cholinergic receptor function.
Topics: Acetylcholine; Alzheimer Disease; Animals; Aziridines; Choline; Disease Models, Animal; Electric Sti | 1995 |
Effect of dizocilpine (MK-801) on the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
Topics: Acetylcholine; Animals; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dronabinol | 1994 |
Swim test immobility co-segregates with serotonergic but not cholinergic sensitivity in cross-breeds of Flinders Line rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Depressive Disorder; Disease | 1994 |
[The characteristics of a parkinsonian syndrome induced in an experiment by a deficiency of nigrostriatal dopamine and by stimulation of the cholinergic neurons of the caudate nucleus].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetylcholine; Animals; C | 1993 |
Protective efficacy of a hypothermic pharmacological agent in gerbil forebrain ischemia.
Topics: Animals; Body Temperature; Brain Ischemia; Cell Survival; Disease Models, Animal; Gerbillinae; Hippo | 1993 |
Synthesis and muscarinic activities of 3-(pyrazolyl)-1,2,5,6-tetrahydropyridine derivatives.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Analysis of Variance; Animals; Bind | 1996 |
Cholinergic/serotonergic interactions in hypothermia: implications for rat models of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Body Temperature Regulation; Depressive Diso | 1998 |
Pharmacological features of masculine sexual behavior in an animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Clo | 1998 |
Ontogeny of muscarinic cholinergic supersensitivity in the Flinders Sensitive Line rat.
Topics: Animals; Binding Sites; Body Temperature; Depression; Disease Models, Animal; Dose-Response Relation | 1999 |
Oxotremorine-induced cerebral hyperemia does not predict infarction volume in spontaneously hypertensive or stroke-prone rats.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Coloring Agents; Disease Models, Animal; Endoth | 2000 |
New non competitive AMPA antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsa | 2000 |
Elucidating the role of muscarinic receptors in psychosis.
Topics: Alzheimer Disease; Animals; Cell Fractionation; Cell Line; Cell Membrane; Cerebral Cortex; Disease M | 2001 |
The production of an alternative laboratory model of the Parkinson syndrome using a new benzylimidoylurea derivative LON 954.
Topics: Animals; Antiparkinson Agents; Benzimidazoles; Disease Models, Animal; Drug Evaluation, Preclinical; | 1977 |
Pharmacological & biochemical characterization of antiparkinson drugs in reserpinized mice.
Topics: Animals; Antiparkinson Agents; Ataxia; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Ma | 1979 |
Pharmacological alleviation of combined cholinergic/noradrenergic lesion-induced memory deficits in rats.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Benzylamines; Cholinergic Agents; Cholinergic Fibers | 1991 |
Drug-induced purposeless chewing: animal model of dyskinesia or nausea?
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Disease M | 1990 |
Early development of muscarinic supersensitivity in a genetic animal model of depression.
Topics: Aging; Animals; Atropine Derivatives; Body Temperature; Body Weight; Brain; Depression; Disease Mode | 1991 |
Antidepressant effects of rolipram in a genetic animal model of depression: cholinergic supersensitivity and weight gain.
Topics: Albuterol; Animals; Antidepressive Agents; Avoidance Learning; Body Temperature; Brain; Depressive D | 1989 |
Qualitative and quantitative analysis of muscarinic acetylcholine receptors in the piebald lethal mouse model of Hirschsprung's disease.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Colon; Disease Models, Animal; Female; Hirschsprung Di | 1985 |
L-DOPA: chemical modifications and biological evaluation.
Topics: Animals; Antiparkinson Agents; Blepharoptosis; Catatonia; Disease Models, Animal; Humans; Hypothermi | 1974 |
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain; | 1973 |
[Tremorine as test for evaluating antitremor agents (a review of the literature)].
Topics: Animals; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Guinea P | 1973 |
Effect of gamma-hydroxybutyric acid on tremor induced oxotremorin.
Topics: Animals; Atropine; Brain Chemistry; Disease Models, Animal; Drug Antagonism; Drug Synergism; Female; | 1972 |