oxotremorine has been researched along with Ache in 22 studies
Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The action of the benzomorphan narcotic antagonists Mr-1452 and Mr-2266 and their respective (+) isomers Mr-1453 and Mr-2267 as well as the antimuscarinic agent atropine upon oxotremorine (OTMN)-induced analgesia, tremor, and hypothermia were investigated in mice." | 7.66 | Some observations on the effects of enantiomers of two benzomorphan narcotic antagonists and atropine on analgesia, tremor and hypothermia produced by oxotremorine. ( Ben-Sreti, MM; Sewell, RD; Upton, N, 1982) |
| " Oxotremorine-induced tremor and salivation in mice were delayed after extremely high dosage of levocabastine; however, these were much less effective than those seen after diphenhydramine and ketotifen." | 3.68 | Central effect of the potent long-acting H1-antihistamine levocabastine. ( Aoki, I; Kamei, C; Tasaka, K; Tsujimoto, S; Yoshida, T, 1990) |
| "The action of the benzomorphan narcotic antagonists Mr-1452 and Mr-2266 and their respective (+) isomers Mr-1453 and Mr-2267 as well as the antimuscarinic agent atropine upon oxotremorine (OTMN)-induced analgesia, tremor, and hypothermia were investigated in mice." | 3.66 | Some observations on the effects of enantiomers of two benzomorphan narcotic antagonists and atropine on analgesia, tremor and hypothermia produced by oxotremorine. ( Ben-Sreti, MM; Sewell, RD; Upton, N, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (40.91) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blednov, YA | 1 |
| Stoffel, M | 1 |
| Alva, H | 1 |
| Harris, RA | 1 |
| Vetulani, J | 1 |
| Pavone, F | 4 |
| Przewłocka, B | 2 |
| Borghi, V | 1 |
| Nalepa, I | 1 |
| Hegab, MI | 1 |
| Abdulla, MM | 1 |
| Pedigo, NW | 1 |
| Minor, LD | 1 |
| Krumrei, TN | 1 |
| Lewis, JW | 1 |
| Cannon, JT | 1 |
| Liebeskind, JC | 1 |
| Ben-Sreti, MM | 1 |
| Sewell, RD | 1 |
| Upton, N | 1 |
| Gomeza, J | 1 |
| Shannon, H | 2 |
| Kostenis, E | 1 |
| Felder, C | 1 |
| Zhang, L | 1 |
| Brodkin, J | 1 |
| Grinberg, A | 1 |
| Sheng, H | 1 |
| Wess, J | 1 |
| Przewlocka, B | 1 |
| Mika, J | 1 |
| Capone, F | 2 |
| Machelska, H | 2 |
| Thor, KB | 1 |
| Muhlhauser, MA | 1 |
| Sauerberg, P | 1 |
| Springer, JP | 1 |
| Womer, DE | 1 |
| Shannon, HE | 1 |
| Abelson, KS | 1 |
| Höglund, AU | 1 |
| Widman, M | 1 |
| Rosin, D | 1 |
| Dewey, WL | 1 |
| Fagioli, S | 1 |
| Matsumoto, RR | 1 |
| Walker, JM | 1 |
| Tasaka, K | 1 |
| Kamei, C | 1 |
| Tsujimoto, S | 1 |
| Yoshida, T | 1 |
| Aoki, I | 1 |
| Ghelardini, C | 1 |
| Malmberg-Aiello, P | 1 |
| Giotti, A | 1 |
| Malcangio, M | 1 |
| Bartolini, A | 1 |
| Hamm, RJ | 1 |
| Knisely, JS | 1 |
| Zorn, SH | 1 |
| Enna, SJ | 1 |
| Slater, P | 1 |
| Nistri, A | 1 |
| Pepeu, G | 1 |
| Cammelli, E | 1 |
| Spina, L | 1 |
| De Bellis, AM | 1 |
| Phan, DV | 1 |
| Dóda, M | 1 |
| Bite, A | 1 |
| György, L | 1 |
22 other studies available for oxotremorine and Ache
| Article | Year |
|---|---|
A pervasive mechanism for analgesia: activation of GIRK2 channels.
Topics: Analgesia; Analgesics; Animals; Baclofen; Benzoxazines; Clonidine; Crosses, Genetic; Ethanol; Female | 2003 |
The interaction of tetrahydroisoquinoline derivatives with antinociceptive action of morphine and oxotremorine in mice.
Topics: Acetylcholine; Analgesics; Animals; Central Nervous System; Drug Synergism; Male; Mice; Morphine; No | 2003 |
4-Chloro-2,2-disubstituted chromen-3-carboxaldehyde: synthesis of some fused polycyclic heterocycles as anti-inflammatory, analgesic, anticonvulsant, and antiparkinsonian agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antiparkinson Agents; Benzopyrans; C | 2006 |
Cholinergic drug effects and brain muscarinic receptor binding in aged rats.
Topics: Aging; Animals; Male; Motor Activity; Oxotremorine; Pain; Quinuclidinyl Benzilate; Rats; Rats, Inbre | 1984 |
Involvement of central muscarinic cholinergic mechanisms in opioid stress analgesia.
Topics: Animals; Electroshock; Endorphins; Male; Morphine; Naltrexone; Oxotremorine; Pain; Rats; Rats, Inbre | 1983 |
Some observations on the effects of enantiomers of two benzomorphan narcotic antagonists and atropine on analgesia, tremor and hypothermia produced by oxotremorine.
Topics: Animals; Atropine; Benzomorphans; Body Temperature; Drug Interactions; Male; Mice; Morphinans; Narco | 1982 |
Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice.
Topics: Analgesia; Animals; Brain; Embryo, Mammalian; Female; Gene Expression; Genomic Library; Homozygote; | 1999 |
Intrathecal oxotremorine affects formalin-induced behavior and spinal nitric oxide synthase immunoreactivity in rats.
Topics: Animals; Behavior, Animal; Formaldehyde; Immunohistochemistry; Injections, Spinal; Male; Muscarinic | 1999 |
Antinociception after both peripheral and intrathecal injection of oxotremorine is modulated by spinal nitric oxide.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intraperitoneal; Injection | 1999 |
Central muscarinic inhibition of lower urinary tract nociception.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Cholinergic Agents; Cholinesterase Inhibitors; | 2000 |
Reversal of pertussis toxin-induced thermal allodynia by muscarinic cholinergic agonists in mice.
Topics: Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hot Temperature; Injections, S | 2000 |
Intravenously administered oxotremorine and atropine, in doses known to affect pain threshold, affect the intraspinal release of acetylcholine in rats.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intrav | 2002 |
Effects of divalent cations, lanthanum, cation chelators and an ionophore on acetylcholine antinociception.
Topics: Acetylcholine; Animals; Calcimycin; Calcium Chloride; Cations, Divalent; Chelating Agents; Drug Inte | 1978 |
Serotonergic influence on cholinergic-induced analgesia: differences in two inbred strains of mice.
Topics: Acetylcholine; Analgesia; Animals; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Mice, | 1992 |
Inhibition of rubral neurons by noxious and non-noxious pressure.
Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hindlimb; Ibotenic A | 1991 |
Central effect of the potent long-acting H1-antihistamine levocabastine.
Topics: Acetates; Animals; Avoidance Learning; Central Nervous System; Electroencephalography; Histamine H1 | 1990 |
Investigation into atropine-induced antinociception.
Topics: Analgesics; Animals; Atropine; Dicyclomine; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techn | 1990 |
Developmental differences in the analgesia produced by the central cholinergic system.
Topics: Age Factors; Animals; Male; N-Methylscopolamine; Oxotremorine; Pain; Rats; Rats, Inbred Strains; Rea | 1987 |
GABA uptake inhibitors produce a greater antinociceptive response in the mouse tail-immersion assay than other types of GABAergic drugs.
Topics: Analgesics; Animals; Biological Transport; Brain; Corpus Striatum; GABA Antagonists; gamma-Aminobuty | 1985 |
Effect of 6-hydroxydopamine on some actions of tremorine and oxotremorine.
Topics: Amines; Animals; Body Temperature; Brain Chemistry; Catecholamines; Dopamine; Dose-Response Relation | 1974 |
Effects of morphine on brain and spinal acetylcholine levels and nociceptive threshold in the frog.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain; Brain Chemistry; Differential Threshold; Dose-R | 1974 |
Antin ociceptive activity of nicotine.
Topics: Acetates; Analgesia; Animals; Dimethylphenylpiperazinium Iodide; Drug Tolerance; Injections, Intrape | 1973 |