oxophenylarsine has been researched along with Pheochromocytoma in 4 studies
oxophenylarsine: inhibits protein-tyrosine-phosphatase
phenylarsine oxide : An arsine oxide derived from phenylarsine.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Overexpression of NCS-1 caused a shift in the dose-response curve of inhibition of ATP-evoked secretion using phenylarsine oxide, an inhibitor of phosphatidylinositol 4-OH kinase (PI4K)." | 1.32 | Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells. ( Greenwood, S; Hilfiker, S; Jeromin, A; Rajebhosale, M; Vidugiriene, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rajebhosale, M | 1 |
| Greenwood, S | 1 |
| Vidugiriene, J | 1 |
| Jeromin, A | 1 |
| Hilfiker, S | 1 |
| Schaefer, T | 1 |
| Wiedemann, C | 1 |
| Gitler, C | 1 |
| Burger, MM | 1 |
| Altin, JG | 1 |
| Bradshaw, RA | 2 |
| Eveleth, DD | 1 |
1 review available for oxophenylarsine and Pheochromocytoma
| Article | Year |
|---|---|
Effects of arsenicals on the secretory process in chromaffin cells.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Arsenicals; Cattle; Cells, Cultured; Diamide; Dit | 1994 |
3 other studies available for oxophenylarsine and Pheochromocytoma
| Article | Year |
|---|---|
Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine Triphosphate; Animals; Arsenicals; Calcium Signaling; Cal | 2003 |
Production of 1,2-diacylglycerol in PC12 cells by nerve growth factor and basic fibroblast growth factor.
Topics: Acids; Adenosine; Adrenal Gland Neoplasms; Animals; Arsenicals; Calcium; Carbachol; Culture Media; D | 1990 |
Internalization and cycling of nerve growth factor in PC12 cells: interconversion of type II (fast) and type I (slow) nerve growth factor receptors.
Topics: Animals; Arsenicals; Chloroquine; Digitonin; Endocytosis; Monensin; Nerve Growth Factors; Pheochromo | 1988 |