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oxophenylarsine and Leukemia, Promyelocytic, Acute

oxophenylarsine has been researched along with Leukemia, Promyelocytic, Acute in 2 studies

oxophenylarsine: inhibits protein-tyrosine-phosphatase
phenylarsine oxide : An arsine oxide derived from phenylarsine.

Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.

Research Excerpts

ExcerptRelevanceReference
"We studied the cytotoxic effect of an organic arsenical compound, phenylarsine oxide (PAO) on an acute promyelocytic leukemia (APL) cell line (NB4) and an As2O3-resistant NB4 subline (NB4/As)."3.72Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway. ( Hayash, H; Horii, T; Kitamura, K; Kobayashi, M; Maekawa, M; Naito, K; Nakamura, S; Naoe, T; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hussain, L1
Maimaitiyiming, Y1
Su, L1
Wang, QQ1
Naranmandura, H1
Sahara, N1
Takeshita, A1
Kobayashi, M1
Shigeno, K1
Nakamura, S1
Shinjo, K1
Naito, K1
Maekawa, M1
Horii, T1
Ohnishi, K1
Kitamura, K1
Naoe, T1
Hayash, H1
Ohno, R1

Other Studies

2 other studies available for oxophenylarsine and Leukemia, Promyelocytic, Acute

ArticleYear
Phenylarsine Oxide Can Induce Degradation of PLZF-RARĪ± Variant Fusion Protein of Acute Promyelocytic Leukemia.
    Chemical research in toxicology, 2019, 04-15, Volume: 32, Issue:4

    Topics: Arsenicals; HeLa Cells; Humans; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion

2019
Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:5

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cyclin

2004