oxophenylarsine has been researched along with Benign Cerebellar Neoplasms in 1 studies
oxophenylarsine: inhibits protein-tyrosine-phosphatase
phenylarsine oxide : An arsine oxide derived from phenylarsine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Arsenicals active in Hh pathway antagonism include arsenic trioxide (ATO), a curative agent in clinical use for acute promyelocytic leukemia (APL); in our studies, ATO inhibited growth of Hh pathway-driven medulloblastoma allografts derived from Ptch+/-p53-/- mice within a range of serum levels comparable to those achieved in treatment of human APL." | 3.76 | Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector. ( Beachy, PA; Gardner, D; Kim, J; Lee, JJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 2 |
| Lee, JJ | 1 |
| Gardner, D | 1 |
| Beachy, PA | 1 |
1 other study available for oxophenylarsine and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
Topics: Animals; Arsenic Trioxide; Arsenicals; Arsenites; Cerebellar Neoplasms; Dose-Response Relationship, | 2010 |