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oxonic acid and Laryngeal Neoplasms

oxonic acid has been researched along with Laryngeal Neoplasms in 21 studies

Oxonic Acid: Antagonist of urate oxidase.

Laryngeal Neoplasms: Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.

Research Excerpts

ExcerptRelevanceReference
"We examined the completion rate, safety, and adverse events in patients with T2N0 glottic carcinoma who received chemoradiotherapy with S-1 (tegafur-gimeracil-oteracil potassium)."3.80Radiotherapy concurrent with S-1 and radiotherapy alone for T2N0 glottic carcinoma: a retrospective comparative study. ( Higashino, M; Ichihara, S; Kawata, R; Lee, K; Nishikawa, S; Uesugi, Y, 2014)
"Eligible patients had T1b or T2 glottic squamous cell carcinomas."2.80Critical evaluation of a prospective study of concurrent chemoradiotherapy with S-1 for early glottic carcinoma. ( Fujimoto, Y; Hiramatsu, M; Itoh, J; Itoh, Y; Kawamura, M; Kimura, K; Kubota, S; Naganawa, S; Nakahara, R; Okada, T; Shibata, T, 2015)
"Chemoradiation based on S-1, a novel oral antitumor agent of fluorinated pyrimidines, is the treatment for T2N0 glottic carcinoma; however, the optimal scheduling and dosing have still not been established."2.72A phase I study of concurrent chemoradiotherapy with S-1 for T2N0 glottic carcinoma. ( Inoue, T; Kiba, T; Murata, H; Nagata, K; Nagata, M; Shimode, Y; Tomoda, K; Tsuji, H; Yamashita, T; Yukawa, H, 2006)
" We analyzed the clinical response, survival rate, acute adverse events, and late swallowing toxicity."1.51Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma. ( Ohashi, T; Ohnishi, M; Okuda, H; Takada, N; Takagi, C; Takahashi, H, 2019)
"In resectable advanced laryngeal cancer, S-1 adjuvant chemotherapy is an effective and feasible treatment option to control distant metastases following reduced RADPLAT."1.38Adjuvant chemotherapy with an oral fluoropyrimidine, S-1, following reduced RADPLAT in advanced laryngeal cancer. ( Endo, K; Kondo, S; Murono, S; Wakisaka, N; Yoshizaki, T, 2012)
"CCRT is the mainstay of treatment for laryngeal cancer in our department, given our goals of achieving organ and functional preservation, as well as radical cure."1.37[Laryngeal cancer treatment outcomes in our department]. ( Akiyama, R; Egawa, S; Hayashi, T; Ikeda, K; Ikenoya, Y; Sanbe, T; Shimane, T; Sugimoto, A; Uzuki, A, 2011)
"We herein report our examination of 20 laryngeal cancer cases receiving concomitant therapy with S-1, Nedaplatin, and radiation (hereinafter, referred to as SN therapy) in our department from April 2005 to December 2008."1.36[Effectiveness of concomitant therapy with S-1, nedaplatin, and radiation for laryngeal cancer]. ( Furuya, A; Kaburagi, A; Kamakazu, K; Kobayashi, S; Monden, T; Mori, T; Ono, T; Sanbe, T; Shimane, T; Suzaki, H, 2010)
" Regulating the dosage and intervals of S-1 enabled the patients in both cases to survive with cancer as outpatients for 2 years and 2 months after the initial visit (1 year and 10 months from the start of the administration of S-1) in the former case and 3 years from the initial visit (2 years and 1 month from the start of the administration of S-1) in the latter case."1.35[Two cases of head and neck squamous cell carcinoma in which S-1 administration resulted in long-term sustained QOL]. ( Furuya, A; Kobayashi, S; Monden, T; Mori, T; Ono, T; Sanbe, T; Shimane, T; Suzaki, H, 2009)
"We report two head and neck cancer patients who responded to TS-1."1.32[Two head and neck cancer patients who responded to chemotherapy consisting of only TS-1]. ( Horiuchi, C; Kagesato, Y; Kawai, S; Mikami, Y; Mochimatsu, I; Tanigaki, Y; Tsukuda, M, 2003)
"A patient with advanced recurrent laryngeal cancer complicated with cervical lymph node metastasis was successfully treated with chemoradiotherapy with an oral anticancer drug, TS-1."1.32[A case of lymph node metastasis after total laryngectomy successfully treated with chemoradiotherapy with TS-1]. ( Suzuki, S; Yoshihara, T, 2003)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (33.33)29.6817
2010's14 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sano, D2
Tanabe, T1
Kubota, A3
Miyamoto, S1
Tanigaki, Y4
Okami, K1
Komatsu, M2
Ikoma, R1
Suzuki, K2
Akazawa, Y1
Kobayashi, S3
Yamada, Y1
Oridate, N3
Kitani, Y2
Furukawa, M1
Hori, Y1
Nakayama, Y1
Nonaka, T1
Mizoguchi, N1
Hatakeyama, H1
Kimura, K2
Itoh, Y2
Okada, T2
Kubota, S2
Kawamura, M2
Nakahara, R2
Oie, Y1
Kozai, Y1
Takase, Y1
Tsuzuki, H1
Nishio, N1
Hiramatsu, M2
Fujimoto, Y2
Mizutani, T1
Hirakawa, A1
Naganawa, S2
Okuda, H1
Ohnishi, M1
Takahashi, H1
Takagi, C1
Takada, N1
Ohashi, T1
Higashino, M1
Kawata, R1
Lee, K1
Nishikawa, S1
Ichihara, S1
Uesugi, Y1
Taguchi, T2
Takahashi, M1
Nishimura, G1
Shiono, O1
Sakuma, Y1
Taguri, M1
Hata, M1
Itoh, J1
Shibata, T1
Shimane, T3
Mori, T2
Ono, T2
Monden, T2
Furuya, A2
Sanbe, T4
Suzaki, H3
Abo, H1
Tsukuda, M3
Matsuda, H1
Horiuchi, C2
Watanabe, M1
Niho, T1
Kaburagi, A1
Kamakazu, K1
Nakayama, M1
Hayakawa, K1
Okamoto, M1
Niibe, Y1
Ishiyama, H1
Kotani, S1
Nonoshita, T1
Shioyama, Y1
Nakamura, K1
Nakashima, T1
Ohga, S1
Yoshitake, T1
Ohnishi, K1
Terashima, K1
Asai, K1
Honda, H1
Kuratomi, Y1
Satoh, S1
Monji, M1
Yokogawa, K1
Shimazu, R1
Tokumaru, S1
Inokuchi, A1
Morimoto, M1
Takemura, H1
Yui, T1
Suzuki, T1
Egawa, S1
Akiyama, R1
Ikenoya, Y1
Uzuki, A1
Sugimoto, A1
Hayashi, T1
Ikeda, K1
Wakisaka, N1
Kondo, S1
Endo, K1
Murono, S1
Yoshizaki, T1
Mikami, Y1
Kawai, S1
Kagesato, Y1
Mochimatsu, I1
Suzuki, S1
Yoshihara, T1
Tsuji, H2
Nagata, M2
Inoue, T2
Minami, T1
Iwai, H1
Ohnishi, S1
Yukawa, H2
Ogura, M1
Yamashita, T2
Nagata, K2
Kiba, T1
Shimode, Y1
Murata, H1
Tomoda, K1
Ikeda, Y1
Yabuki, K1
Mitake, D1
Ishitoya, J1

Trials

5 trials available for oxonic acid and Laryngeal Neoplasms

ArticleYear
Phase II study of concurrent chemoradiotherapy with S-1 in patients with stage II (T2N0M0) squamous cell carcinoma of the Pharynx or Larynx.
    Japanese journal of clinical oncology, 2014, Volume: 44, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Combination

2014
Critical evaluation of a prospective study of concurrent chemoradiotherapy with S-1 for early glottic carcinoma.
    Anticancer research, 2015, Volume: 35, Issue:4

    Topics: Aged; Carcinoma, Squamous Cell; Chemoradiotherapy; Combined Modality Therapy; Drug Combinations; Fem

2015
Phase I/II trial of concurrent use of S-1 and radiation therapy for T2 glottic cancer.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:10

    Topics: Aged; Aged, 80 and over; Anemia; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Administr

2010
[Clinical phase I trial of concurrent chemo-radiotherapy with S-1 for T2NO glottic carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Deglutit

2006
A phase I study of concurrent chemoradiotherapy with S-1 for T2N0 glottic carcinoma.
    Oncology, 2006, Volume: 71, Issue:5-6

    Topics: Adult; Aged; Dermatitis; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Drug Combi

2006

Other Studies

16 other studies available for oxonic acid and Laryngeal Neoplasms

ArticleYear
Addition of S-1 to radiotherapy for treatment of T2N0 glottic cancer: Results of the multiple-center retrospective cohort study in Japan with a propensity score analysis.
    Oral oncology, 2019, Volume: 99

    Topics: Adult; Aged; Aged, 80 and over; Drug Combinations; Female; Glottis; Humans; Japan; Laryngeal Neoplas

2019
Impact of combined modality treatment with radiotherapy and S-1 on T2N0 laryngeal cancer: Possible improvement in survival through the prevention of second primary cancer and distant metastasis.
    Oral oncology, 2017, Volume: 71

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Combination

2017
Study Protocol: Prospective Study of Concurrent Chemoradiotherapy with S-1 and Hypofractionated Radiotherapy for Outpatients with Early Glottic Squamous Cell Carcinomas
    Asian Pacific journal of cancer prevention : APJCP, 2018, May-26, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Combinations; Fema

2018
Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma.
    Auris, nasus, larynx, 2019, Volume: 46, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; D

2019
Radiotherapy concurrent with S-1 and radiotherapy alone for T2N0 glottic carcinoma: a retrospective comparative study.
    Auris, nasus, larynx, 2014, Volume: 41, Issue:4

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma; Chemoradiotherapy; Drug Combina

2014
[Two cases of head and neck squamous cell carcinoma in which S-1 administration resulted in long-term sustained QOL].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:7

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Combination

2009
[Successful treatment results of S-1 administration in 2 patients, one with a remnant tumor of the larynx and metastatic tumors to the lung, and another with a metastatic tumor in the neck from the hypopharynx].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cel

2009
[Effectiveness of concomitant therapy with S-1, nedaplatin, and radiation for laryngeal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combina

2010
Concurrent chemoradiotherapy with S-1 for T2N0 glottic squamous cell carcinoma.
    Journal of radiation research, 2010, Volume: 51, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Th

2010
[A comparative study of concurrent chemoradiotherapy with S-1 or CDDP for pharyngeal or laryngeal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:8

    Topics: Aged; Aged, 80 and over; Cisplatin; Combined Modality Therapy; Drug Combinations; Female; Humans; La

2010
[Efficacy of concomitant therapy with S-1, CDGP, and radiation for laryngeal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Th

2010
[Laryngeal cancer treatment outcomes in our department].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; F

2011
Adjuvant chemotherapy with an oral fluoropyrimidine, S-1, following reduced RADPLAT in advanced laryngeal cancer.
    The Annals of otology, rhinology, and laryngology, 2012, Volume: 121, Issue:8

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy,

2012
[Two head and neck cancer patients who responded to chemotherapy consisting of only TS-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; He

2003
[A case of lymph node metastasis after total laryngectomy successfully treated with chemoradiotherapy with TS-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:12

    Topics: Antimetabolites, Antineoplastic; Drug Combinations; Humans; Laryngeal Neoplasms; Laryngectomy; Lymph

2003
[Concurrent chemoradiotherapy with S-1 for T2N0 glottic carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; D

2008