oxonic acid has been researched along with Kidney Neoplasms in 9 studies
Oxonic Acid: Antagonist of urate oxidase.
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to assess the safety, tolerance, pharmacokinetics and clinical activity of S-1 combined with sorafenib in patients with mRCC." | 2.80 | Phase I/II study of S-1 in combination with sorafenib for metastatic renal cell carcinoma. ( Akaza, H; Eto, M; Fujisawa, M; Hashine, K; Naito, S; Ozono, S; Sakai, H; Shinohara, N; Tomita, Y, 2015) |
| "Patients with renal cell carcinoma were eligible if they had had at least one regimen of cytokine for metastatic disease." | 2.79 | Final results of a phase II study of S-1 in patients with cytokine-refractory metastatic renal cell carcinoma. ( Akaza, H; Fujisawa, M; Hashine, K; Mizokami, A; Naito, S; Nakagawa, M; Nishikido, M; Shinohara, N; Tatsugami, K; Tomita, Y; Tsukamoto, T, 2014) |
| "Patients continued treatment until disease progression, unacceptable toxicity, or withdrawal of consent." | 2.75 | An early phase II trial of S-1 in Japanese patients with cytokine-refractory metastatic renal cell carcinoma. ( Akaza, H; Fujimoto, H; Naito, S; Tsukamoto, T; Usami, M, 2010) |
| "Laboratory data showed marked leukocytosis with increased serum and urinary G-CSF." | 1.37 | Combination therapy with sorafenib and S-1 for renal cell carcinoma producing granulocyte colony-stimulating factor. ( Baba, S; Kinoshita, M; Kurita, Y; Kyono, Y; Mugiya, S; Ozono, S; Takayama, T, 2011) |
| "We report herein a case with stage IV gastric cancer previously treated with TS-1 completely responding to second-line chemotherapy with weekly paclitaxel therapy." | 1.33 | [A case of stage IV gastric cancer previously treated with TS-1 completely responding to second-line chemotherapy with weekly paclitaxel therapy]. ( Jingu, K; Kagaya, A; Ochiai, T; Sasagawa, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naito, S | 5 |
| Tatsugami, K | 2 |
| Shinohara, N | 3 |
| Tomita, Y | 3 |
| Mizokami, A | 1 |
| Fujisawa, M | 3 |
| Hashine, K | 2 |
| Nishikido, M | 2 |
| Nakagawa, M | 1 |
| Tsukamoto, T | 3 |
| Akaza, H | 5 |
| Sakai, H | 1 |
| Eto, M | 3 |
| Ozono, S | 2 |
| Usami, M | 2 |
| Fujimoto, H | 1 |
| Kyono, Y | 1 |
| Takayama, T | 1 |
| Kinoshita, M | 1 |
| Kurita, Y | 1 |
| Mugiya, S | 1 |
| Baba, S | 1 |
| Namiki, M | 1 |
| Vogelzang, NJ | 1 |
| Takeuchi, A | 1 |
| Shiota, M | 1 |
| Yokomizo, A | 1 |
| Inokuchi, J | 1 |
| Kuroiwa, K | 1 |
| Kiyoshima, K | 1 |
| Jingu, K | 1 |
| Sasagawa, K | 1 |
| Kagaya, A | 1 |
| Ochiai, T | 1 |
1 review available for oxonic acid and Kidney Neoplasms
| Article | Year |
|---|---|
[The possibility of S-1 for the treatment of patients with urological cancers].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Drug Adm | 2006 |
4 trials available for oxonic acid and Kidney Neoplasms
| Article | Year |
|---|---|
Final results of a phase II study of S-1 in patients with cytokine-refractory metastatic renal cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Cytokines; Disease-Free Surviva | 2014 |
Phase I/II study of S-1 in combination with sorafenib for metastatic renal cell carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal | 2015 |
An early phase II trial of S-1 in Japanese patients with cytokine-refractory metastatic renal cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Cytokines; Disease Progression; | 2010 |
Multicenter phase II trial of S-1 in patients with cytokine-refractory metastatic renal cell carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Dihydrouracil Dehydrogenase (NADP); Di | 2010 |
4 other studies available for oxonic acid and Kidney Neoplasms
| Article | Year |
|---|---|
Combination therapy with sorafenib and S-1 for renal cell carcinoma producing granulocyte colony-stimulating factor.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Drug | 2011 |
Another step toward the cure of metastatic renal cell carcinoma?
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Drug Combinations; Humans; K | 2010 |
Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression.
Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Com | 2011 |
[A case of stage IV gastric cancer previously treated with TS-1 completely responding to second-line chemotherapy with weekly paclitaxel therapy].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Chemothera | 2005 |