oxonic acid has been researched along with Kidney Failure, Chronic in 4 studies
Oxonic Acid: Antagonist of urate oxidase.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of febuxostat (Fx), a non-purine and selective xanthine oxidase inhibitor, on glomerular microcirculatory changes in 5/6 nephrectomy (5/6 Nx) Wistar rats with and without oxonic acid (OA)-induced hyperuricemia was evaluated." | 7.74 | Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia. ( Avila-Casado, C; Franco, M; Johnson, RJ; Sánchez-Lozada, LG; Soto, V; Tapia, E; Wessale, JL; Zhao, L, 2008) |
| "The effect of febuxostat (Fx), a non-purine and selective xanthine oxidase inhibitor, on glomerular microcirculatory changes in 5/6 nephrectomy (5/6 Nx) Wistar rats with and without oxonic acid (OA)-induced hyperuricemia was evaluated." | 3.74 | Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia. ( Avila-Casado, C; Franco, M; Johnson, RJ; Sánchez-Lozada, LG; Soto, V; Tapia, E; Wessale, JL; Zhao, L, 2008) |
| "Tegafur is a well-known prodrug of 5-FU." | 1.42 | [A Case Report of Successful Chemotherapy with Tegafur/Gimeracil/Oteracil and Nab-Paclitaxel for Gastric Cancer with Chronic Renal Failure]. ( Kurashima, Y; Miyazaki, T; Ohata, K; Ohno, K; Okawa, M; Tanaka, S; Uenishi, T; Yamamoto, T, 2015) |
| " S-1 has safe and potent antitumor effects in patients with gastric cancer via these respective functions." | 1.32 | Safety and efficacy of S-1, a novel oral fluorouracil antitumor drug, for a chronic renal failure patient maintained on hemodialysis. ( Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Okazaki, H; Oshitani, N; Sasaki, E; Shiba, M; Suto, R; Tanigawa, T; Tominaga, K; Watanabe, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamamoto, T | 1 |
| Miyazaki, T | 1 |
| Kurashima, Y | 1 |
| Ohata, K | 1 |
| Okawa, M | 1 |
| Tanaka, S | 1 |
| Uenishi, T | 1 |
| Ohno, K | 1 |
| Tominaga, K | 1 |
| Higuchi, K | 1 |
| Okazaki, H | 1 |
| Suto, R | 1 |
| Hamaguchi, M | 1 |
| Tanigawa, T | 1 |
| Sasaki, E | 1 |
| Shiba, M | 1 |
| Watanabe, T | 1 |
| Fujiwara, Y | 1 |
| Oshitani, N | 1 |
| Matsumoto, T | 1 |
| Arakawa, T | 1 |
| Tanaka, T | 1 |
| Fujita, S | 1 |
| Tanaka, N | 2 |
| Ooka, M | 1 |
| Okajima, S | 1 |
| Sánchez-Lozada, LG | 1 |
| Tapia, E | 1 |
| Soto, V | 1 |
| Avila-Casado, C | 1 |
| Franco, M | 1 |
| Wessale, JL | 1 |
| Zhao, L | 1 |
| Johnson, RJ | 1 |
4 other studies available for oxonic acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
[A Case Report of Successful Chemotherapy with Tegafur/Gimeracil/Oteracil and Nab-Paclitaxel for Gastric Cancer with Chronic Renal Failure].
Topics: Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Kidney | 2015 |
Safety and efficacy of S-1, a novel oral fluorouracil antitumor drug, for a chronic renal failure patient maintained on hemodialysis.
Topics: Administration, Oral; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Kidney | 2004 |
[TS-1 treatment for progressive gastric cancer in a patient on chronic dialysis--assessment of dosage regimen by monitoring blood concentrations of therapeutic drugs (TDM)].
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Area Under Curve; Drug Administration Schedu | 2005 |
Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia.
Topics: Animals; Disease Models, Animal; Febuxostat; Hyperuricemia; Kidney; Kidney Failure, Chronic; Male; M | 2008 |