oxonic acid has been researched along with Gouty Arthritis in 10 studies
Oxonic Acid: Antagonist of urate oxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mouse gouty arthritis model was established by injections of potassium oxonate (PO), monosodium urate (MSU) and pyroptosis suppressor disulfiram." | 8.12 | Pyroptosis inhibition alleviates potassium oxonate- and monosodium urate-induced gouty arthritis in mice. ( Hou, X; Liu, X; Tian, J; Wang, B; Xiang, L; Xie, B; Zhou, D, 2022) |
| " The RSGE treatment dose-dependently reduced PO- and MSU-induced paw edema, serum TNF-α, IL-1β, IL-6, IL-12, uric acid, and BUN, while significantly elevated serum IL-10, urinary uric acid and creatinine levels as compared with the respective values in the hyperuricemic and gouty mice group (vehicle group)." | 7.91 | Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice. ( Chang, Y; Liang, C; Liang, G; Nie, Y; Xiao, D; Zeng, S; Zhan, S; Zheng, Q; Zheng, X, 2019) |
| "Mouse gouty arthritis model was established by injections of potassium oxonate (PO), monosodium urate (MSU) and pyroptosis suppressor disulfiram." | 4.12 | Pyroptosis inhibition alleviates potassium oxonate- and monosodium urate-induced gouty arthritis in mice. ( Hou, X; Liu, X; Tian, J; Wang, B; Xiang, L; Xie, B; Zhou, D, 2022) |
| " Both WP and EP extracts showed pronounced antihyperuricemia activities, with a remarkable decline in serum uric acid and a marked increase in urine uric acid in hyperuricemic mice." | 4.02 | Antihyperuricemia and antigouty arthritis effects of Persicaria capitata herba in mice. ( Chen, TX; Dong, L; Fu, Y; Guan, HY; He, X; Liao, SG; Tang, KF; Xu, GB; Yang, XS; Yang, YX; Zhang, CL; Zhang, JJ; Zhu, QF, 2021) |
| " The RSGE treatment dose-dependently reduced PO- and MSU-induced paw edema, serum TNF-α, IL-1β, IL-6, IL-12, uric acid, and BUN, while significantly elevated serum IL-10, urinary uric acid and creatinine levels as compared with the respective values in the hyperuricemic and gouty mice group (vehicle group)." | 3.91 | Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice. ( Chang, Y; Liang, C; Liang, G; Nie, Y; Xiao, D; Zeng, S; Zhan, S; Zheng, Q; Zheng, X, 2019) |
| " affine extract was evaluated in an experimental model with potassium oxonate (PO) induced hyperuricemia in mice which was used to evaluate anti-hyperuricemia activity and xanthine oxidase (XO) inhibition." | 3.85 | Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis. ( Cheng, L; Hu, YJ; Li, LN; Liang, WQ; Liu, PG; Pu, JB; Xu, P; Yang, QQ; Zhang, HJ; Zhang, YQ; Zhou, J, 2017) |
| " trichocarpha, its ethyl acetate fraction and its main bioactive compounds could be useful to treat gouty arthritis by countering hyperuricemia and inflammation." | 3.78 | Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents. ( de Paula, CA; de Souza Filho, JD; de Souza, MR; Grabe-Guimarães, A; Pereira de Resende, ML; Saúde-Guimarães, DA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, CL | 1 |
| Zhang, JJ | 1 |
| Zhu, QF | 1 |
| Guan, HY | 1 |
| Yang, YX | 1 |
| He, X | 1 |
| Fu, Y | 1 |
| Chen, TX | 1 |
| Dong, L | 1 |
| Yang, XS | 1 |
| Tang, KF | 1 |
| Xu, GB | 1 |
| Liao, SG | 1 |
| Tian, J | 1 |
| Wang, B | 1 |
| Xie, B | 1 |
| Liu, X | 2 |
| Zhou, D | 1 |
| Hou, X | 1 |
| Xiang, L | 1 |
| Zhang, HJ | 1 |
| Li, LN | 1 |
| Zhou, J | 1 |
| Yang, QQ | 1 |
| Liu, PG | 1 |
| Xu, P | 1 |
| Liang, WQ | 1 |
| Cheng, L | 1 |
| Zhang, YQ | 1 |
| Pu, JB | 1 |
| Hu, YJ | 1 |
| Liang, G | 1 |
| Nie, Y | 1 |
| Chang, Y | 1 |
| Zeng, S | 1 |
| Liang, C | 1 |
| Zheng, X | 1 |
| Xiao, D | 1 |
| Zhan, S | 1 |
| Zheng, Q | 1 |
| Yang, TH | 1 |
| Yan, DX | 1 |
| Huang, XY | 1 |
| Hou, B | 1 |
| Ma, YB | 1 |
| Peng, H | 1 |
| Zhang, XM | 1 |
| Chen, JJ | 1 |
| Geng, CA | 1 |
| Lemos Lima, Rde C | 1 |
| Ferrari, FC | 1 |
| de Souza, MR | 2 |
| de Sá Pereira, BM | 1 |
| de Paula, CA | 2 |
| Saúde-Guimarães, DA | 2 |
| Zhu, F | 1 |
| Yin, L | 1 |
| Ji, L | 1 |
| Yang, F | 1 |
| Zhang, G | 1 |
| Shi, L | 1 |
| Xu, L | 1 |
| Chen, R | 1 |
| Shang, Y | 1 |
| Jiao, B | 1 |
| Huang, C | 1 |
| Pereira de Resende, ML | 1 |
| Grabe-Guimarães, A | 1 |
| de Souza Filho, JD | 1 |
| Silva, CR | 1 |
| Fröhlich, JK | 1 |
| Oliveira, SM | 1 |
| Cabreira, TN | 1 |
| Rossato, MF | 1 |
| Trevisan, G | 1 |
| Froeder, AL | 1 |
| Bochi, GV | 1 |
| Moresco, RN | 1 |
| Athayde, ML | 1 |
| Ferreira, J | 1 |
10 other studies available for oxonic acid and Gouty Arthritis
| Article | Year |
|---|---|
Antihyperuricemia and antigouty arthritis effects of Persicaria capitata herba in mice.
Topics: Animals; Arthritis, Gouty; Hyperuricemia; Mice; Oxonic Acid; Plant Extracts; Uric Acid; Xanthine Oxi | 2021 |
Pyroptosis inhibition alleviates potassium oxonate- and monosodium urate-induced gouty arthritis in mice.
Topics: Animals; Arthritis, Gouty; Creatinine; Cytokines; Disease Models, Animal; Disulfiram; Humans; Mice; | 2022 |
Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Chromatography, High Pressure Liquid; Disease M | 2017 |
Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice.
Topics: Animals; Antioxidants; Arthritis, Gouty; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Flavo | 2019 |
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis.
Topics: Anacardiaceae; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Chalcone; Dose-Re | 2019 |
Effects of extracts of leaves from Sparattosperma leucanthum on hyperuricemia and gouty arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Bignoniaceae; Gout Suppressants; Hyperuricemia; | 2015 |
Suppressive effect of Sanmiao formula on experimental gouty arthritis by inhibiting cartilage matrix degradation: An in vivo and in vitro study.
Topics: ADAM Proteins; ADAMTS4 Protein; Animals; Arthritis, Gouty; Cells, Cultured; Chondrocytes; Complex Mi | 2016 |
Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats.
Topics: Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Benzofurans; Depsid | 2008 |
Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Asteraceae; Ethanol; Flavonoids; Hype | 2012 |
The antinociceptive and anti-inflammatory effects of the crude extract of Jatropha isabellei in a rat gout model.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Biomarkers, Pharmacological; Disease | 2013 |