oxonic acid has been researched along with EHS Tumor in 2 studies
Oxonic Acid: Antagonist of urate oxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These findings suggest that local DC therapy in combination with TS-1 and OK-432 may well be a useful strategy for the treatment of solid tumors, and that TLR4 signaling is involved in the success of this therapy." | 1.32 | [Anti-tumor effect of intratumoral administration of dendritic cells in combination with TS-1 and OK-432]. ( Ahmed, SU; Okamoto, M; Oshikawa, T; Sato, M; Tano, T, 2004) |
| " The reduction of gastrointestinal (GI) toxicity, induced in the host by 5-FU, was modulated by potassium oxonate (Oxo), an inhibitor of orotate phosphoribosyltransferase that catalyzes the phosphorylation of 5-FU, a process believed to be responsible for the toxic effects of 5-FU." | 1.29 | Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. ( Fukushima, M; Kato, T; Ohshimo, H; Shimamato, Y; Shirasaka, T; Yamaguchi, M; Yonekura, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okamoto, M | 1 |
| Ahmed, SU | 1 |
| Oshikawa, T | 1 |
| Tano, T | 1 |
| Sato, M | 1 |
| Shirasaka, T | 1 |
| Shimamato, Y | 1 |
| Ohshimo, H | 1 |
| Yamaguchi, M | 1 |
| Kato, T | 1 |
| Yonekura, K | 1 |
| Fukushima, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Trial of Gemcitabine and S-1 for Patients With Advanced Biliary Tract Cancer[NCT02146703] | Phase 2 | 38 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| Phase III Trial of S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for First Line Treatment of Advanced Gastric Cancer[NCT01671449] | Phase 3 | 338 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for oxonic acid and EHS Tumor