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oxonic acid and Dihydropyrimidine Dehydrogenase Deficiency

oxonic acid has been researched along with Dihydropyrimidine Dehydrogenase Deficiency in 3 studies

Oxonic Acid: Antagonist of urate oxidase.

Dihydropyrimidine Dehydrogenase Deficiency: An autosomal recessive disorder affecting DIHYDROPYRIMIDINE DEHYDROGENASE and causing familial pyrimidinemia. It is characterized by thymine-uraciluria in homozygous deficient patients. Even a partial deficiency in the enzyme leaves individuals at risk for developing severe 5-FLUOROURACIL-associated toxicity.

Research Excerpts

ExcerptRelevanceReference
"We report a rare patient with a DPD deficiency."1.33[A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency]. ( Arai, K; Hashimoto, T; Hiruma, K; Iwasaki, Y; Matsumoto, H; Saze, Z; Takahashi, K; Yamaguchi, T; Yamashita, Y; Yasutome, M, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Milano, G1
Aragane, H1
Suchi, K1
Shimomura, M1
Katano, T1
Yasui, H1
Kan, K1
Hashimoto, T1
Arai, K1
Iwasaki, Y1
Saze, Z1
Takahashi, K1
Yamaguchi, T1
Matsumoto, H1
Yasutome, M1
Hiruma, K1
Yamashita, Y1

Other Studies

3 other studies available for oxonic acid and Dihydropyrimidine Dehydrogenase Deficiency

ArticleYear
Fluoropyrimidines and DPD testing: is there truly an inexorable link?
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 113

    Topics: Antineoplastic Agents; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP

2019
[Severe bone marrow suppression during adjuvant chemotherapy for gastric cancer by S-1 and its possible relationship to dihydropyrimidine dehydrogenase deficiency].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Bone Marrow; Chemotherapy, Adjuvant; Dihydropyrimidine Dehydr

2010
[A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Adult; Anorexia; Antimetabolites, Antineoplastic; Bone Neoplasms; Cerebral Hemorrhage; Dihydropyrimi

2006