oxonic acid has been researched along with Carcinoma, Adenosquamous in 17 studies
Oxonic Acid: Antagonist of urate oxidase.
Carcinoma, Adenosquamous: A mixed adenocarcinoma and squamous cell or epidermoid carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with metastatic pancreatic cancer that progressed during first-line gemcitabine-based chemotherapy or recurred during or after post-operative gemcitabine-based adjuvant treatment were randomly assigned (1:1) to receive either S-1 (40-60 mg, twice daily for 4 weeks in a 6-week cycle) or TAS-118 (S-1 40-60 mg plus leucovorin 25 mg, twice daily for 1 week in a 2-week cycle)." | 2.90 | TAS-118 (S-1 plus leucovorin) versus S-1 in patients with gemcitabine-refractory advanced pancreatic cancer: a randomised, open-label, phase 3 study (GRAPE trial). ( Boku, N; Chang, HM; Chung, IJ; Fukuzawa, K; Furukawa, M; Furuse, J; Hara, H; Hyodo, I; Ikeda, M; Ioka, T; Kanai, M; Kim, JS; Maguchi, H; Mizuno, N; Nakamori, S; Okusaka, T; Omuro, Y; Park, JO; Sasahira, N; Sugimori, K; Takeuchi, M; Ueno, H; Ueno, M; Yamaguchi, T; Yukisawa, S, 2019) |
| "Gemcitabine was administered at a dose of 1000 mg/m(2) over 30 min on days 1 and 8, and oral S-1 at a dose of 40 mg/m(2) twice daily from days 1 to 14, repeated every 3 weeks." | 2.76 | Multicenter phase II study of gemcitabine and S-1 combination therapy (GS Therapy) in patients with metastatic pancreatic cancer. ( Boku, N; Funakoshi, A; Furuse, J; Moriyasu, F; Nakamori, S; Ohkawa, S; Okusaka, T; Sato, T; Tanaka, K; Ueno, H; Yamao, K; Yokosuka, O, 2011) |
| "Gastric adenosquamous carcinoma is a rare malignancy with a poor prognosis." | 1.40 | [A case of gastric adenosquamous carcinoma with peritoneal dissemination in which treatment with S-1 plus paclitaxel therapy resulted in improved long-term survival]. ( Hirano, M; Ichinose, M; Mizumoto, A; Ozamoto, Y; Takao, N; Tatsuno, M; Togawa, T; Yamamoto, Y; Yonemura, Y, 2014) |
| "Chemotherapy is rarely used in treating adenosquamous carcinoma, and it has been difficult to establish treatment guidelines due to the paucity of cases." | 1.35 | Adenosquamous carcinoma of maxillary sinus: case showing complete response to S-1. ( Hanata, K; Ishikawa, K; Nanjo, H; Suzuki, S, 2009) |
| " Five patients showed grade 3 and 4 adverse reactions, all hematological." | 1.35 | Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer. ( Ishikawa, K; Suzuki, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 13 (76.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hata, Y | 1 |
| Kiribayashi, T | 1 |
| Kishi, K | 1 |
| Nagashima, M | 1 |
| Nakayama, T | 1 |
| Ikeda, S | 1 |
| Kadokura, M | 1 |
| Ozeki, Y | 1 |
| Otsuka, H | 1 |
| Murakami, Y | 1 |
| Takagi, K | 1 |
| Iyoda, A | 1 |
| Ioka, T | 3 |
| Ueno, M | 2 |
| Ueno, H | 2 |
| Park, JO | 1 |
| Chang, HM | 1 |
| Sasahira, N | 1 |
| Kanai, M | 1 |
| Chung, IJ | 1 |
| Ikeda, M | 3 |
| Nakamori, S | 3 |
| Mizuno, N | 2 |
| Omuro, Y | 2 |
| Yamaguchi, T | 2 |
| Hara, H | 2 |
| Sugimori, K | 1 |
| Furuse, J | 4 |
| Maguchi, H | 1 |
| Furukawa, M | 1 |
| Fukuzawa, K | 1 |
| Kim, JS | 1 |
| Yukisawa, S | 1 |
| Takeuchi, M | 1 |
| Okusaka, T | 5 |
| Boku, N | 2 |
| Hyodo, I | 2 |
| Saito, H | 1 |
| Oyama, K | 1 |
| Fushida, S | 1 |
| Tsukada, T | 1 |
| Okamoto, K | 1 |
| Nakanuma, N | 1 |
| Kinoshita, J | 1 |
| Makino, I | 1 |
| Nakamura, K | 1 |
| Hayashi, H | 1 |
| Inokuchi, M | 1 |
| Nakagawara, H | 1 |
| Miyashita, T | 1 |
| Fujita, H | 1 |
| Tajima, H | 1 |
| Takamura, H | 1 |
| Ninomiya, I | 1 |
| Kitagawa, H | 1 |
| Fujimura, T | 1 |
| Ohta, T | 1 |
| Sumiyoshi, H | 1 |
| Matsushita, A | 1 |
| Nakamura, Y | 1 |
| Yamahatsu, K | 1 |
| Katsuno, A | 1 |
| Uchida, E | 1 |
| Hirano, M | 1 |
| Ozamoto, Y | 1 |
| Ichinose, M | 1 |
| Togawa, T | 1 |
| Takao, N | 1 |
| Mizumoto, A | 1 |
| Tatsuno, M | 1 |
| Yamamoto, Y | 1 |
| Yonemura, Y | 1 |
| Ohkawa, S | 4 |
| Isayama, H | 1 |
| Fukutomi, A | 1 |
| Yamaguchi, K | 1 |
| Funakoshi, A | 2 |
| Nagase, M | 2 |
| Hamamoto, Y | 1 |
| Tsuchiya, Y | 1 |
| Baba, H | 1 |
| Ishii, H | 2 |
| Sho, M | 1 |
| Matsumoto, S | 1 |
| Yamada, N | 1 |
| Yanagimoto, H | 1 |
| Unno, M | 1 |
| Ichikawa, Y | 1 |
| Takahashi, S | 1 |
| Watanabe, G | 1 |
| Wakabayashi, G | 1 |
| Egawa, N | 1 |
| Tsuda, M | 1 |
| Hosotani, R | 1 |
| Hamada, C | 2 |
| Hijikawa, T | 1 |
| Yoshida, R | 1 |
| Yamada, M | 1 |
| Nakatani, K | 1 |
| Tokuhara, K | 1 |
| Kitade, H | 1 |
| Shikata, N | 1 |
| Yoshioka, K | 1 |
| Kon, M | 1 |
| Kobayashi, S | 1 |
| Irie, K | 1 |
| Goda, Y | 1 |
| Moriya, S | 1 |
| Tezuka, S | 1 |
| Tanaka, M | 3 |
| Morimoto, M | 1 |
| Komatsu, Y | 1 |
| Tsuji, A | 1 |
| Iguchi, H | 1 |
| Ishiguro, A | 1 |
| Kitano, M | 1 |
| Satoh, T | 1 |
| Takeda, K | 1 |
| Kida, M | 1 |
| Eguchi, K | 1 |
| Ito, T | 1 |
| Munakata, M | 1 |
| Itoi, T | 1 |
| Sakata, Y | 1 |
| Kaneta, A | 1 |
| Tsuchiya, T | 1 |
| Saito, T | 1 |
| Otani, S | 1 |
| Ito, F | 1 |
| Miura, J | 1 |
| Suzuki, S | 2 |
| Hanata, K | 1 |
| Nanjo, H | 1 |
| Ishikawa, K | 2 |
| Yamao, K | 2 |
| Yokosuka, O | 1 |
| Tanaka, K | 1 |
| Moriyasu, F | 1 |
| Sato, T | 2 |
| Ito, Y | 1 |
| Yonemoto, N | 1 |
| Miyakawa, H | 1 |
| Sato, K | 1 |
| Ebi, M | 1 |
| Shimura, T | 1 |
| Yamada, S | 1 |
| Hirata, Y | 1 |
| Tsukamoto, H | 1 |
| Okamoto, Y | 1 |
| Mizoshita, T | 1 |
| Tanida, S | 1 |
| Kataoka, H | 1 |
| Kamiya, T | 1 |
| Inagaki, H | 1 |
| Joh, T | 1 |
| Nomura, M | 1 |
| Inoue, Y | 1 |
| Fujita, S | 1 |
| Sakao, J | 1 |
| Hirota, M | 1 |
| Souda, S | 1 |
| Ikeda, E | 1 |
| Shigematsu, T | 1 |
| Hidaka, K | 1 |
| Nishikawa, A | 1 |
| Katayama, M | 1 |
| Okajima, T | 1 |
| Kawahara, T | 1 |
| Banba, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for oxonic acid and Carcinoma, Adenosquamous
| Article | Year |
|---|---|
[A case of gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Adenosqu | 2013 |
7 trials available for oxonic acid and Carcinoma, Adenosquamous
| Article | Year |
|---|---|
Adherence and feasibility of 2 treatment schedules of S-1 as adjuvant chemotherapy for patients with completely resected advanced lung cancer: a multicenter randomized controlled trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Carcinoma, Non-Small-Cell Lu | 2017 |
TAS-118 (S-1 plus leucovorin) versus S-1 in patients with gemcitabine-refractory advanced pancreatic cancer: a randomised, open-label, phase 3 study (GRAPE trial).
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2019 |
Randomised phase II trial of S-1 plus oxaliplatin vs S-1 in patients with gemcitabine-refractory pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc | 2015 |
Unexpected Side Effects of a High S-1 Dose: Subanalysis of a Phase III Trial Comparing Gemcitabine, S-1 and Combinatorial Treatments for Advanced Pancreatic Cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Deox | 2016 |
Randomised phase II trial of irinotecan plus S-1 in patients with gemcitabine-refractory pancreatic cancer.
Topics: Adenocarcinoma; Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; A | 2017 |
Multicenter phase II study of gemcitabine and S-1 combination therapy (GS Therapy) in patients with metastatic pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ad | 2011 |
A multicenter phase II trial of S-1 with concurrent radiation therapy for locally advanced pancreatic cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti | 2013 |
9 other studies available for oxonic acid and Carcinoma, Adenosquamous
| Article | Year |
|---|---|
[Radical resection of a locally advanced pancreatic tail adenosquamous carcinoma treated with S-1 and gemcitabine as neoadjuvant chemotherapy - a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Deoxycytidine; Drug | 2014 |
[A case of gastric adenosquamous carcinoma with peritoneal dissemination in which treatment with S-1 plus paclitaxel therapy resulted in improved long-term survival].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Adenosquamous; Chemotherapy, Adju | 2014 |
[A Case of Adenosquamous Carcinoma of the Ascending Colon].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Chemotherapy, Adjuvant; Colectomy; | 2015 |
[Pancreatic Adenosquamous Carcinoma That Developed after Resection of IPMA in the Pancreatic Tail].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Carcinoma, Pancreati | 2016 |
Adenosquamous carcinoma of maxillary sinus: case showing complete response to S-1.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ad | 2009 |
Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Carcinoma, Sq | 2009 |
A patient with gastric adenosquamous carcinoma with intraperitoneal free cancer cells who remained recurrence-free with postoperative S-1 chemotherapy.
Topics: Aged; Antineoplastic Agents; Ascitic Fluid; Carcinoma, Adenosquamous; Combined Modality Therapy; Dru | 2012 |
[A case of gastric adenosquamous carcinoma with abdominal paraaortic lymph node metastases successfully treated by TS-1 plus CDDP neoadjuvant chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Carcinoma, Adenosquamous; Chemothe | 2006 |
[A case of adenosquamous gastric carcinoma successfully treated with TS-1, low-dose CDDP and docetaxel as neoadjuvant chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Cisplatin; Combined | 2007 |