oxonic acid has been researched along with Cancer of Mouth in 42 studies
Oxonic Acid: Antagonist of urate oxidase.
Excerpt | Relevance | Reference |
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" In the present study, we conducted a phase I study to examine local control of S-1 in the combination with DOC using super-selective intra-arterial infusion with oral cancer." | 2.74 | [Clinical phase I trial of S-1 in the combination with DOC using super-selective intra-arterial infusion with oral cancer]. ( Harada, K; Horinaga, D; Mano, T; Mihara, M; Okafuji, M; Uchida, K; Ueyama, Y; Wada, N, 2009) |
"Patients with pathologically confirmed squamous cell carcinoma and at least one measurable lesion were enrolled." | 2.73 | Multi-institutional phase II trial of S-1 in patients with oral squamous cell carcinoma. ( Hamakawa, H; Harada, K; Nagahata, S; Nagayama, M; Osaki, T; Ryoke, K; Sato, M; Ueyama, Y; Yoshimura, Y, 2008) |
" We analyzed the clinical response, survival rate, acute adverse events, and late swallowing toxicity." | 1.51 | Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma. ( Ohashi, T; Ohnishi, M; Okuda, H; Takada, N; Takagi, C; Takahashi, H, 2019) |
"In our department, patients with oral squamous cell carcinoma(OSCC)received preoperative chemotherapy containing S-1 to prevent the growth and dissemination of tumors during the waiting time before definitive surgery." | 1.51 | [Clinicopathological Evaluation of Preoperative Chemotherapy Containing S-1 as a Treatment for Patients with Oral Squamous Cell Carcinoma during Waiting Time for Surgery]. ( Amino, K; Imai, T; Iwai, S; Kanesaki, T; Katou, I; Matsumiya, Y; Meshii, N; Nakazawa, M; Niki, A; Omae, M; Onishi, T; Ota, Y; Suematsu, M; Sumi, T; Takeshita, A; Ueda, M, 2019) |
"We clinically analyzed 8 oral squamous cell carcinoma patients showing a complete response(CR)to chemotherapy with S-1 alone." | 1.37 | [Clinical analyses of oral squamous cell carcinoma patients showing a complete response to chemotherapy with S-1 alone]. ( Aoki, M; Iwamoto, O; Koga, C; Koga, M; Kusukawa, J; Nakamura, M, 2011) |
" The present study indicates that further investigation is needed to determine the best dosing and dosing schedule." | 1.37 | [The clinical effect of combination therapy for oral cancer with S-1, superselective intra-arterial chemotherapy, and radiation therapy]. ( Fukumoto, S; Higuchi, T; Horinouchi, Y; Uehara, S; Yamamoto, C; Yasumori, K; Yoshida, M; Yoshikawa, H, 2011) |
" In this study, the response of human OSCC cells to Lentinan alone and in combination with S-1 was examined using nude mouse xenograft models." | 1.36 | Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo. ( Harada, K; Itashiki, Y; Takenawa, T; Ueyama, Y, 2010) |
"Cepharanthine is a biscoclaurine alkaloid extracted from Stephania cepharantha Hayata, which is widely used for the treatment of many acute and chronic diseases, and can exert antitumor effects on several human cancer cells." | 1.35 | Effects of cepharanthine alone and in combination with fluoropyrimidine anticancer agent, S-1, on tumor growth of human oral squamous cell carcinoma xenografts in nude mice. ( Ferdous, T; Harada, K; Itashiki, Y; Mano, T; Mori, Y; Takii, M; Ueyama, Y, 2009) |
"Approximately 50% of oral squamous cell carcinomas (OSCC) exhibit cervical lymph node metastasis." | 1.35 | S-1 mediates the inhibition of lymph node metastasis in oral cancer cells. ( Ando, Y; Hatori, M; Kurihara, Y; Sato, H; Shintani, S; Shirota, T; Tachikawa, T; Takayama, S, 2009) |
"A 76-year-old patient with oral squamous cell carcinoma was treated by chemotherapy with S-1." | 1.34 | [A case of oral squamous cell carcinoma responding to S-1]. ( Bando, T; Harada, K; Tamatani, T; Yoshida, H, 2007) |
"In the patients with oral squamous cell carcinoma (OSCC), S-1 was given orally according to a 4-week application followed by 2-week rest regimen (4-week regimen), or a 2-week application followed by a 1-week rest regimen (2-week regimen)." | 1.34 | Investigation of optimal schedule of concurrent radiotherapy with S-1 for oral squamous cell carcinoma. ( Ferdous, T; Harada, K; Yoshida, H, 2007) |
"Twenty-five patients with oral squamous cell carcinoma (OSCC) received S-1 80 mg/m2/day." | 1.33 | Thymidylate synthase expression in oral squamous cell carcinoma predicts response to S-1. ( Harada, K; Kawashima, Y; Sato, M; Yoshida, H, 2006) |
"We report a case of advanced squamous cell carcinoma in the left buccal mucosa, upper gingiva, and maxillary sinus (T4N0M0) showing a complete response to oral chemotherapy with TS-1." | 1.32 | [An advanced case of squamous cell carcinoma in the left buccal mucosa, upper gingiva, and maxillary sinus (T4N0M0) showing a complete response to chemotherapy with TS-1]. ( Mishima, K; Nakamura, H; Obara, S; Yamamoto, K; Yoshimura, Y, 2004) |
"Human oral cancer cell lines were used as subcutaneous xenografts in nude mice." | 1.32 | Combined effects of the oral fluoropyrimidine anticancer agent, S-1 and radiation on human oral cancer cells. ( Harada, K; Kawaguchi, S; Onoue, T; Sato, M; Yoshida, H, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 21 (50.00) | 29.6817 |
2010's | 20 (47.62) | 24.3611 |
2020's | 1 (2.38) | 2.80 |
Authors | Studies |
---|---|
Yoshida, R | 2 |
Nagata, M | 1 |
Hirosue, A | 1 |
Kawahara, K | 1 |
Nakamoto, M | 1 |
Hirayama, M | 1 |
Takahashi, N | 1 |
Matsuoka, Y | 1 |
Sakata, J | 1 |
Nakashima, H | 1 |
Arita, H | 1 |
Hiraki, A | 4 |
Shinohara, M | 4 |
Kikuchi, K | 1 |
Nakayama, H | 4 |
Takakura, H | 1 |
Domae, S | 1 |
Ono, T | 2 |
Sasaki, A | 2 |
Shetty, SS | 1 |
Vishal Rao, US | 1 |
Okuda, H | 1 |
Ohnishi, M | 1 |
Takahashi, H | 1 |
Takagi, C | 1 |
Takada, N | 1 |
Ohashi, T | 1 |
Matsumiya, Y | 1 |
Imai, T | 1 |
Takeshita, A | 1 |
Meshii, N | 1 |
Katou, I | 1 |
Iwai, S | 2 |
Suematsu, M | 1 |
Omae, M | 1 |
Kanesaki, T | 1 |
Ota, Y | 1 |
Onishi, T | 1 |
Amino, K | 1 |
Sumi, T | 2 |
Niki, A | 1 |
Ueda, M | 1 |
Nakazawa, M | 4 |
Seki-Soda, M | 1 |
Sano, T | 1 |
Koshi, H | 1 |
Yokoo, S | 2 |
Oyama, T | 1 |
Ferdous, T | 3 |
Harada, K | 13 |
Kin, T | 1 |
Harada, T | 1 |
Ueyama, Y | 5 |
Kasamatsu, A | 1 |
Uzawa, K | 1 |
Minakawa, Y | 1 |
Ishige, S | 1 |
Kasama, H | 1 |
Endo-Sakamoto, Y | 1 |
Ogawara, K | 1 |
Shiiba, M | 1 |
Takiguchi, Y | 1 |
Tanzawa, H | 1 |
Watanabe, H | 1 |
Itoh, H | 1 |
Tsuchiya, Y | 1 |
Miyagi, N | 1 |
Sugiyama, T | 1 |
Nakai, Y | 1 |
Shinozaki, Y | 1 |
Noguchi, T | 1 |
Jinbu, Y | 1 |
Kusama, M | 1 |
Negishi, A | 1 |
Ogawa, M | 1 |
Kosugi, K | 1 |
Takayama, Y | 1 |
Gomi, A | 1 |
Miyazaki, H | 1 |
Kishimoto, K | 1 |
Yoshida, S | 1 |
Yoshihama, Y | 2 |
Nishiyama, A | 1 |
Okafuji, M | 1 |
Mano, T | 2 |
Mihara, M | 1 |
Uchida, K | 1 |
Horinaga, D | 1 |
Wada, N | 1 |
Itashiki, Y | 2 |
Takii, M | 1 |
Mori, Y | 1 |
Koga, M | 3 |
Anegawa, E | 2 |
Yoh, J | 1 |
Tsuyama, H | 1 |
Sakaino, H | 1 |
Iwamoto, O | 3 |
Koga, C | 3 |
Kusukawa, J | 3 |
Nomura, T | 1 |
Murakami, R | 2 |
Toya, R | 1 |
Teshima, K | 2 |
Nakahara, A | 1 |
Hirai, T | 2 |
Yoshitake, Y | 1 |
Ota, K | 1 |
Obayashi, T | 1 |
Yamashita, Y | 2 |
Oya, N | 1 |
Sato, H | 1 |
Hatori, M | 1 |
Ando, Y | 1 |
Kurihara, Y | 1 |
Takayama, S | 1 |
Shirota, T | 1 |
Tachikawa, T | 1 |
Shintani, S | 3 |
Harada, H | 2 |
Omura, K | 2 |
Takenawa, T | 1 |
Nagai, H | 2 |
Takamaru, N | 1 |
Ohe, G | 1 |
Uchida, D | 2 |
Tamatani, T | 2 |
Fujisawa, K | 1 |
Iwamoto, S | 1 |
Miyamoto, Y | 2 |
Kawasaki, G | 1 |
Yoshitomi, I | 1 |
Yanamoto, S | 1 |
Yamada, S | 1 |
Mizuno, A | 1 |
Nakamura, M | 1 |
Aoki, M | 2 |
Yamamoto, C | 1 |
Yoshikawa, H | 1 |
Fukumoto, S | 1 |
Higuchi, T | 1 |
Yoshida, M | 1 |
Horinouchi, Y | 1 |
Uehara, S | 1 |
Yasumori, K | 1 |
Nakaguchi, Y | 1 |
Tsujita, N | 1 |
Tomitaka, E | 1 |
Furusawa, M | 1 |
Tamura, T | 1 |
Tanio, K | 1 |
Kidani, K | 1 |
Ogawa, N | 1 |
Kodani, I | 1 |
Ryoke, K | 2 |
Tomioka, H | 1 |
Yamamoto, K | 1 |
Obara, S | 1 |
Mishima, K | 1 |
Nakamura, H | 1 |
Yoshimura, Y | 2 |
Kawaguchi, S | 2 |
Onoue, T | 1 |
Yoshida, H | 7 |
Sato, M | 6 |
Ohnishi, T | 2 |
Chisoku, H | 2 |
Katagiri, W | 1 |
Doi, T | 1 |
Takase, T | 1 |
Yui, S | 2 |
Miwa, Y | 1 |
Fukuda, Y | 2 |
Kishino, M | 2 |
Yura, Y | 2 |
Kawashima, Y | 4 |
Ohmae, M | 1 |
Hino, S | 1 |
Nakashiro, K | 1 |
Hamakawa, H | 2 |
Maruoka, Y | 1 |
Ando, T | 1 |
Ogiuchi, Y | 1 |
Ogiuchi, H | 1 |
Tezuka, M | 1 |
Bando, T | 1 |
Nagayama, M | 1 |
Nagahata, S | 1 |
Osaki, T | 1 |
Nakata, A | 1 |
Fukuda, M | 1 |
Iwanami, Y | 1 |
Ito, H | 1 |
Takano, H | 1 |
Nanjo, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Clinical Study of Toripalimab Monoclonal Antibody Combined With Gemcitabine/5--fluoropyrimidine in the Treatment of Advanced Cholangiocarcinoma[NCT03982680] | Phase 2 | 30 participants (Anticipated) | Interventional | 2019-07-13 | Recruiting | ||
A Prospective, Single-arm Study of Simultaneous Modulated Accelerated Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Carcinoma.[NCT02606916] | Phase 2 | 42 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for oxonic acid and Cancer of Mouth
Article | Year |
---|---|
[Reinforcement of warfarin action in a patient administered S-1].
Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Cardiomyopathy, Hypertrophic; Cerebral Infarc | 2015 |
9 trials available for oxonic acid and Cancer of Mouth
Article | Year |
---|---|
[Clinical phase I trial of S-1 in the combination with DOC using super-selective intra-arterial infusion with oral cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Dose-Response Relationship, Drug; D | 2009 |
Phase II study of preoperative concurrent chemoradiation therapy with S-1 in patients with T4 oral squamous cell carcinoma.
Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; | 2010 |
Preoperative concurrent chemotherapy with S-1 and radiotherapy for locally advanced squamous cell carcinoma of the oral cavity: phase I trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 2010 |
Multicenter phase II trial of preoperative chemoradiotherapy with S-1 for locally advanced oral squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Comb | 2013 |
Phase II study of a novel oral formation of 5-fluorouracil in combination with low-dose cisplatin as preoperative chemotherapy of oral squamous cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2005 |
[Clinical trial of chemotherapy identified according to chemosensitivity assay for oral cancer patients with unresectable recurrent lesions].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedu | 2006 |
[Phase I study of concurrent radiotherapy with S-1 for oral squamous cell carcinoma].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; D | 2006 |
[Preoperative chemotherapy with S-1 and low-dose cisplatin for oral squamous cell carcinoma].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy | 2006 |
Multi-institutional phase II trial of S-1 in patients with oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Dose-Response Relat | 2008 |
32 other studies available for oxonic acid and Cancer of Mouth
Article | Year |
---|---|
Efficacy of adjuvant chemotherapy with S-1 in stage II oral squamous cell carcinoma patients: A comparative study using the propensity score matching method.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Combinati | 2020 |
The Immunological Impact of Chemotherapy on the Tumor Microenvironment of Oral Squamous Cell Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; B7-H1 Antigen; Carcinoma, Squamous Cell; Case | 2017 |
8 "S" in oral cancer.
Topics: Humans; Mouth Neoplasms; Oxonic Acid | 2019 |
Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; D | 2019 |
[Clinicopathological Evaluation of Preoperative Chemotherapy Containing S-1 as a Treatment for Patients with Oral Squamous Cell Carcinoma during Waiting Time for Surgery].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Combinations; Humans; | 2019 |
Histopathological changes in tumor budding between biopsy and resected specimens from patients treated with preoperative S-1 chemotherapy for oral cancer.
Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Drug Combinations; Humans; Mouth | 2019 |
Efficacy of schedule-dependent metronomic S-1 chemotherapy in human oral squamous cell carcinoma cells.
Topics: Administration, Metronomic; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carc | 2013 |
Decorin in human oral cancer: a promising predictive biomarker of S-1 neoadjuvant chemosensitivity.
Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Cell Line, Tumor | 2015 |
[Indication of alternate-day treatment with S-1 in patients with oral cancer].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Comb | 2015 |
[Two cases of giant metastatic cervical lymphnode from oral cancer responding to concurrent chemoradiotherapy with S-1].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug C | 2008 |
Effects of cepharanthine alone and in combination with fluoropyrimidine anticancer agent, S-1, on tumor growth of human oral squamous cell carcinoma xenografts in nude mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylisoquinolines; Blotting, W | 2009 |
Clinical relevance of thymidylate synthase (TS) activity for S-1-based chemotherapy in squamous cell carcinoma of the oral cavity.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Admi | 2010 |
S-1 mediates the inhibition of lymph node metastasis in oral cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tu | 2009 |
Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2010 |
[Evaluation of combination chemotherapy with oral S-1 administration followed by docetaxel by superselective intra-arterial infusion for patients with oral squamous cell carcinomas].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2011 |
Efficacy and toxicity of S-1 plus cisplatin combination neoadjuvant chemotherapy in patients with oral cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Dihydrouracil Dehydrogenase | 2011 |
[Clinical analyses of oral squamous cell carcinoma patients showing a complete response to chemotherapy with S-1 alone].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Combination | 2011 |
[The clinical effect of combination therapy for oral cancer with S-1, superselective intra-arterial chemotherapy, and radiation therapy].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combi | 2011 |
Histopathological changes in parotid and submandibular glands of patients treated with preoperative chemoradiation therapy for oral cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Combinations; Female; | 2012 |
[Successful outcome from treatment modality with low-dose S-1 for three oldest old patients with advanced oral cancer].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Combinations; Female; Humans; Mouth Neoplas | 2012 |
[An advanced case of squamous cell carcinoma in the left buccal mucosa, upper gingiva, and maxillary sinus (T4N0M0) showing a complete response to chemotherapy with TS-1].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Administrat | 2004 |
Combined effects of the oral fluoropyrimidine anticancer agent, S-1 and radiation on human oral cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Survival; Combin | 2004 |
[Preoperative chemotherapy with TS-1 and low dose cisplatin for oral squamous cell carcinoma patients--a preliminary study].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2005 |
S-1, an oral fluoropyrimidine anti-cancer agent, enhanced radiosensitivity in a human oral cancer cell line in vivo and in vitro: involvement possibility of inhibition of survival signal, Akt/PKB.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Drug Combinations; Enzyme Activation; | 2005 |
Thymidylate synthase expression in oral squamous cell carcinoma predicts response to S-1.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Dihydrouracil Dehydrogenase (NADP); Drug C | 2006 |
S-1 inhibits tumorigenicity and angiogenesis of human oral squamous cell carcinoma cells by suppressing expression of phosphorylated Akt, vascular endothelial growth factor and fibroblast growth factor-2.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Combinati | 2007 |
[Nedaplatin (NDP)-combination therapy (NDP/5-FU,NDP/S-1) for oral cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2007 |
[Clinical evaluation of palliative chemotherapy with S-1 for oral cancer patients].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modalit | 2007 |
[A case of advanced oral squamous cell carcinoma responding to concurrent radiotherapy with S-1].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Adm | 2007 |
[A case of oral squamous cell carcinoma responding to S-1].
Topics: Administration, Oral; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Biomarkers, Tumor; | 2007 |
Investigation of optimal schedule of concurrent radiotherapy with S-1 for oral squamous cell carcinoma.
Topics: Aged; Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Combined Modali | 2007 |
[Evaluation of combination chemotherapy with S-1 and docetaxel for patients with oral squamous cell carcinomas].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2007 |