oxonic acid has been researched along with Bile Duct Cancer in 49 studies
Oxonic Acid: Antagonist of urate oxidase.
Excerpt | Relevance | Reference |
---|---|---|
"Although the combination of cisplatin and gemcitabine (GEM) is considered the standard first-line chemotherapy against unresectable hilar cholangiocarcinoma (HC), its efficacy is discouraging." | 9.22 | Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial. ( Guan, J; Li, H; Tong, DN; Zhang, ZY; Zhou, GW; Zhou, ZQ, 2016) |
"The aim of this study was to investigate the prognostic significance of HuR in cholangiocarcinoma patients who received adjuvant gemcitabine-based chemotherapy (AGC) after surgical resection." | 7.88 | Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy. ( Kondo, N; Murakami, Y; Nakagawa, N; Sueda, T; Takahashi, S; Toyota, K; Uemura, K, 2018) |
"We report curative resection of an advanced intrahepatic cholangiocarcinoma that responded well to combined S-1 and gemcitabine chemotherapy(GS therapy)." | 7.83 | [Resection of Advanced Intrahepatic Cholangiocarcinoma after an Effective Response to S-1 and Gemcitabine Combination Therapy]. ( Fukuda, S; Kuga, Y; Moriya, T; Nishida, T, 2016) |
" A 66-year-old male treated with combined paclitaxel (PTX) and S-1 suffered from ARDS following neutropenia." | 7.74 | [Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma]. ( Hanada, N; Hori, K; Kusano, S; Momi, H, 2007) |
"Hilar cholangiocarcinoma is an uncommon cancer and its overall incidence is increasing." | 6.79 | Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma. ( Choi, HJ; Choi, JH; Eum, JB; Jang, JW; Kim, HJ; Kim, MH; Lee, JB; Lee, JL; Lee, SK; Lee, SS; Park, DH; Park, SE; Seo, DW, 2014) |
"Advanced intrahepatic cholangiocarcinoma (ICC) is a highly challenging malignancy characterized by rapid progression and poor prognosis." | 5.56 | Treatment of advanced intrahepatic cholangiocarcinoma with sintilimab combined with tegafur-gimeracil-oteracil potassium capsules (S-1): a case report. ( Cao, L; Li, S; Liu, J; Wang, C, 2020) |
"Simvastatin has inhibitory effects on cancers." | 5.39 | Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism. ( Cai, JP; Chen, W; Hao, XY; Hou, X; Liang, LJ; Yin, XY, 2013) |
"Although the combination of cisplatin and gemcitabine (GEM) is considered the standard first-line chemotherapy against unresectable hilar cholangiocarcinoma (HC), its efficacy is discouraging." | 5.22 | Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial. ( Guan, J; Li, H; Tong, DN; Zhang, ZY; Zhou, GW; Zhou, ZQ, 2016) |
"The aim of this study was to investigate the prognostic significance of HuR in cholangiocarcinoma patients who received adjuvant gemcitabine-based chemotherapy (AGC) after surgical resection." | 3.88 | Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy. ( Kondo, N; Murakami, Y; Nakagawa, N; Sueda, T; Takahashi, S; Toyota, K; Uemura, K, 2018) |
"We report curative resection of an advanced intrahepatic cholangiocarcinoma that responded well to combined S-1 and gemcitabine chemotherapy(GS therapy)." | 3.83 | [Resection of Advanced Intrahepatic Cholangiocarcinoma after an Effective Response to S-1 and Gemcitabine Combination Therapy]. ( Fukuda, S; Kuga, Y; Moriya, T; Nishida, T, 2016) |
" A 66-year-old male treated with combined paclitaxel (PTX) and S-1 suffered from ARDS following neutropenia." | 3.74 | [Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma]. ( Hanada, N; Hori, K; Kusano, S; Momi, H, 2007) |
"Patients with pancreatic cancer commonly suffer from exocrine pancreatic insufficiency, and the ingestion of digestive enzyme supplements may improve absorption." | 2.87 | Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy. ( Abe, K; Gocho, T; Haruki, K; Onda, S; Sakamoto, T; Takano, Y; Uwagawa, T; Yanaga, K, 2018) |
"Hilar cholangiocarcinoma is an uncommon cancer and its overall incidence is increasing." | 2.79 | Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma. ( Choi, HJ; Choi, JH; Eum, JB; Jang, JW; Kim, HJ; Kim, MH; Lee, JB; Lee, JL; Lee, SK; Lee, SS; Park, DH; Park, SE; Seo, DW, 2014) |
"Advanced intrahepatic cholangiocarcinoma (ICC) is a highly challenging malignancy characterized by rapid progression and poor prognosis." | 1.56 | Treatment of advanced intrahepatic cholangiocarcinoma with sintilimab combined with tegafur-gimeracil-oteracil potassium capsules (S-1): a case report. ( Cao, L; Li, S; Liu, J; Wang, C, 2020) |
"In our case, we report a gallbladder cancer with portal vein thrombus." | 1.48 | Gallbladder cancer with tumor thrombus in the portal vein: A case report. ( Bai, XL; Chen, W; Liang, TB; Ma, T; Tu, JJ; Zhang, XZ, 2018) |
"Treatment for unresectable intrahepatic cholangiocarcinoma (ICC) has not been established." | 1.42 | Proton beam therapy for unresectable intrahepatic cholangiocarcinoma. ( Abei, M; Fukuda, K; Hashimoto, T; Ishikawa, H; Mizumoto, M; Ohkawa, A; Okumura, T; Sakae, T; Sakurai, H; Tsuboi, K, 2015) |
"The tumor was diagnosed as hepatocellular carcinoma by MRI and CT." | 1.42 | [Six-year survival with recurrent intrahepatic cholangiocarcinoma achieved by simple S-1 administration]. ( Hirose, T; Ishikawa, Y; Kitamura, K; Miki, A; Minami, T; Morioka, H; Nishihira, T; Otani, T; Suzuki, T; Yoshitani, S, 2015) |
"An 80-year-old man with common bile duct cancer was treated by pancreaticoduodenectomy with D2 lymph node dissection in October 2005." | 1.42 | [A Case of Local Recurrence of Bile Duct Cancer Completely Responding to Chemoradiotherapy with S-1]. ( Hishikawa, H; Matsuura, T; Ozaki, T; Saito, T; Sakaguchi, T; Sueyoshi, H; Tanaka, Y; Ueda, A; Yamamichi, K, 2015) |
"We encountered a case of resected gastric cancer, which occurred concomitantly with intrahepatic cholangiocarcinoma after S-1 plus cisplatin chemotherapy, in a patient who was previously diagnosed with metastatic liver tumor before treatment." | 1.42 | [A Case of Resected Gastric Cancer Occurring Simultaneously with Intrahepatic Cholangiocarcinoma after S-1 plus Cisplatin Chemotherapy]. ( Danno, K; Fujitani, K; Iwase, K; Kawada, J; Kitagawa, A; Kubota, M; Matsuda, C; Matsuura, N; Miyazaki, S; Motoori, M; Nakatsuka, R; Nishimura, M; Nomura, M; Okumura, Y, 2015) |
"Medical records of 133 patients with extrahepatic cholangiocarcinoma who underwent curative resection were reviewed retrospectively." | 1.39 | Perineural invasion in extrahepatic cholangiocarcinoma: prognostic impact and treatment strategies. ( Hashimoto, Y; Kondo, N; Murakami, Y; Muto, T; Nakagawa, N; Sasaki, H; Sudo, T; Sueda, T; Uemura, K; Urabe, K, 2013) |
"Simvastatin has inhibitory effects on cancers." | 1.39 | Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism. ( Cai, JP; Chen, W; Hao, XY; Hou, X; Liang, LJ; Yin, XY, 2013) |
"We report a case of bile duct cancer with a positive surgical margin obtaining long-term survival after S-1 monotherapy." | 1.38 | [A case of bile duct cancer with positive surgical margin obtaining long-term survival after S-1 monotherapy]. ( Harada, N; Hayashi, T; Imaizumi, T; Kaji, S; Koike, N; Morishita, K; Suzuki, M; Suzuki, S; Takeo, Y, 2012) |
"Computed tomography showed nodal recurrence 6 months after surgery." | 1.37 | [A case of long-term survival of a patient with intrahepatic bile duct cancer and early nodal recurrence who responded to S-1 therapy]. ( Kametaka, H; Koyama, T; Makino, H; Seike, K, 2011) |
"A 60-year-old man with intrahepatic cholangiocarcinoma (ICC) underwent a left hepatectomy." | 1.37 | [A case of intrahepatic recurrence of intrahepatic cholangiocarcinoma treated with repeated hepatectomy]. ( Akagi, K; Dono, K; Fujita, J; Hata, T; Ikeda, K; Iwazawa, T; Kawanishi, K; Kitada, M; Miyake, M; Nagai, K; Shimano, T; Shimizu, J, 2011) |
"To cure intrahepatic cholangiocarcinoma (ICC), only a surgical resection is the potential treatment at present." | 1.36 | [A case report--intrahepatic arterial infusion with CDDP and S-1 administration can elicit long-term survival for the patient with recurrenced intrahepatic cholangiocarcinoma after resection]. ( Doki, Y; Eguchi, H; Kobayashi, S; Marubashi, S; Mori, M; Nagano, H; Takeda, Y; Tanemura, M; Tanida, T; Umeshita, H; Wada, H, 2010) |
"Gemcitabine was administered once a week for 3 weeks followed by a week rest." | 1.36 | [A long-term survival case of unresectable intrahepatic cholangiocarcinoma treated with chemotherapy]. ( Mizuyama, Y; Nakagawa, H; Nishihara, T; Ono, Y; Shinto, O; Tamura, T, 2010) |
"A 65-year-old man with common bile duct cancer was treated by pylorus-preserving pancreaticoduodenectomy with D2 lymph node dissection." | 1.35 | [A case of liver metastatic recurrence of bile duct cancer completely responding to single-drug S-1 chemotherapy]. ( Fukao, K; Irabu, S; Kasagawa, T; Kusashio, K; Matsumoto, M; Nobumoto, D; Suzuki, M; Tashima, Y; Tonooka, T; Udagawa, I; Yasutomi, J, 2008) |
"Cholangiocarcinoma is a therapeutically challenging malignancy." | 1.35 | Long-term survival after multimodal therapy in a patient demonstrating intrahepatic cholangiocarcinoma with hilar invasion and intrahepatic metastases. ( Akaike, M; Morinaga, S; Shiozawa, M; Sugano, N; Sugimasa, Y; Wada, H; Yamamoto, Y, 2008) |
"A 66-year-old man was diagnosed with hepatocellular carcinoma with Vp3 by abdominal enhanced CT." | 1.35 | [A case of successful multimodal treatment for combined hepatocellular and cholangiocarcinoma with portal venous tumor thrombus]. ( Doki, Y; Eguchi, H; Hatano, H; Kobayashi, S; Marubashi, S; Mori, M; Murakami, M; Nagano, H; Takeda, Y; Tanemura, M; Tomimaru, Y; Tomokuni, A; Wakasa, K, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 9 (18.37) | 29.6817 |
2010's | 37 (75.51) | 24.3611 |
2020's | 3 (6.12) | 2.80 |
Authors | Studies |
---|---|
Ando, K | 1 |
Tomimaru, Y | 2 |
Iwazawa, T | 2 |
Noguchi, K | 1 |
Nagase, H | 1 |
Ogino, T | 1 |
Hirota, M | 1 |
Oshima, K | 1 |
Tanida, T | 2 |
Noura, S | 1 |
Kawase, T | 1 |
Imamura, H | 1 |
Akagi, K | 2 |
Dono, K | 2 |
Liu, J | 1 |
Wang, C | 1 |
Cao, L | 1 |
Li, S | 1 |
Yang, J | 1 |
Wang, J | 1 |
Zhou, H | 1 |
Wang, Y | 1 |
Huang, H | 1 |
Jin, H | 1 |
Lou, Q | 1 |
Shah, RJ | 1 |
Zhang, X | 1 |
Itano, O | 1 |
Takemura, Y | 1 |
Kishida, N | 1 |
Tamagawa, E | 1 |
Shinozaki, H | 1 |
Ikeda, K | 3 |
Urakami, H | 1 |
Ei, S | 1 |
Hayatsu, S | 1 |
Suzuki, K | 1 |
Sakuragawa, T | 1 |
Ishii, M | 1 |
Shito, M | 1 |
Aiura, K | 1 |
Fujisaki, H | 1 |
Takano, K | 1 |
Matsui, J | 1 |
Minagawa, T | 1 |
Shinoda, M | 1 |
Kitago, M | 1 |
Abe, Y | 1 |
Yagi, H | 1 |
Oshima, G | 1 |
Hori, S | 1 |
Kitagawa, Y | 1 |
Okabayashi, T | 1 |
Shima, Y | 1 |
Iwata, J | 1 |
Morita, S | 1 |
Sumiyoshi, T | 1 |
Sui, K | 1 |
Shimada, Y | 2 |
Iiyama, T | 1 |
Toyota, K | 1 |
Murakami, Y | 3 |
Kondo, N | 3 |
Uemura, K | 3 |
Nakagawa, N | 3 |
Takahashi, S | 1 |
Sueda, T | 3 |
Abe, K | 2 |
Uwagawa, T | 1 |
Haruki, K | 1 |
Takano, Y | 1 |
Onda, S | 1 |
Sakamoto, T | 2 |
Gocho, T | 1 |
Yanaga, K | 1 |
Komiyama, S | 1 |
Izumiya, Y | 1 |
Kimura, Y | 1 |
Nakashima, S | 1 |
Kin, S | 1 |
Kawakami, S | 1 |
Zhang, XZ | 1 |
Tu, JJ | 1 |
Chen, W | 2 |
Ma, T | 1 |
Bai, XL | 1 |
Liang, TB | 1 |
Akahoshi, K | 1 |
Ban, D | 1 |
Kuboki, R | 1 |
Oba, A | 1 |
Ono, H | 1 |
Mitsunori, Y | 1 |
Kudo, A | 1 |
Tanaka, S | 1 |
Tanabe, M | 1 |
Morino, K | 1 |
Seo, S | 1 |
Yoh, T | 1 |
Nishino, H | 1 |
Yamanaka, K | 1 |
Fukumitsu, K | 1 |
Ishii, T | 1 |
Taura, K | 1 |
Okajima, H | 1 |
Kaido, T | 1 |
Uemoto, S | 2 |
Horie, S | 1 |
Ayaki, M | 1 |
Kashiwagi, R | 1 |
Mitsuda, A | 1 |
Tanaka, H | 2 |
Sudo, T | 2 |
Hashimoto, Y | 2 |
Muto, T | 1 |
Sasaki, H | 1 |
Urabe, K | 1 |
Cai, JP | 1 |
Hou, X | 1 |
Liang, LJ | 1 |
Hao, XY | 1 |
Yin, XY | 1 |
Park, DH | 1 |
Lee, SS | 1 |
Park, SE | 1 |
Lee, JL | 1 |
Choi, JH | 1 |
Choi, HJ | 1 |
Jang, JW | 1 |
Kim, HJ | 1 |
Eum, JB | 1 |
Seo, DW | 1 |
Lee, SK | 1 |
Kim, MH | 1 |
Lee, JB | 1 |
Iwahashi, S | 1 |
Utsunomiya, T | 1 |
Imura, S | 1 |
Morine, Y | 1 |
Ikemoto, T | 1 |
Arakawa, Y | 1 |
Saito, Y | 1 |
Ishikawa, D | 1 |
Shimada, M | 1 |
Ohkawa, A | 1 |
Mizumoto, M | 1 |
Ishikawa, H | 1 |
Abei, M | 1 |
Fukuda, K | 1 |
Hashimoto, T | 1 |
Sakae, T | 1 |
Tsuboi, K | 1 |
Okumura, T | 2 |
Sakurai, H | 1 |
Shirasaki, K | 1 |
Morikawa, T | 2 |
Otsuka, H | 1 |
Katayose, Y | 1 |
Unno, M | 2 |
Shiozaki, S | 1 |
Satoh, D | 1 |
Matsukawa, H | 1 |
Yamaguchi, K | 1 |
Takahashi, K | 1 |
Mimura, N | 1 |
Taguchi, K | 1 |
Araki, H | 1 |
Toshima, T | 1 |
Kato, T | 1 |
Miyake, S | 1 |
Miyoshi, H | 1 |
Yoshida, K | 1 |
Choda, Y | 1 |
Tokumoto, N | 1 |
Kanazawa, T | 1 |
Harano, M | 1 |
Ojima, Y | 1 |
Idani, H | 1 |
Okajima, M | 1 |
Ninomiya, M | 1 |
Miki, A | 1 |
Hirose, T | 1 |
Minami, T | 1 |
Morioka, H | 1 |
Suzuki, T | 1 |
Otani, T | 1 |
Kitamura, K | 1 |
Yoshitani, S | 1 |
Ishikawa, Y | 1 |
Nishihira, T | 1 |
Kanomata, H | 1 |
Seyama, Y | 1 |
Tani, K | 1 |
Tanizawa, T | 1 |
Warabi, M | 1 |
Murayama, M | 1 |
Asano, T | 1 |
Takahashi, M | 1 |
Matsuoka, Y | 1 |
Miyamoto, Y | 1 |
Umekita, N | 1 |
Aoki, S | 1 |
Mizuma, M | 1 |
Oyauchi, M | 1 |
Yoshida, H | 1 |
Okada, R | 1 |
Abe, T | 2 |
Sakata, N | 1 |
Nakagawa, K | 1 |
Hayashi, H | 1 |
Motoi, F | 1 |
Naitoh, T | 1 |
Okada, Y | 1 |
Yamamichi, K | 1 |
Sueyoshi, H | 1 |
Tanaka, Y | 1 |
Sakaguchi, T | 1 |
Hishikawa, H | 1 |
Ueda, A | 1 |
Matsuura, T | 1 |
Ozaki, T | 1 |
Saito, T | 1 |
Fushimi, K | 1 |
Omori, T | 1 |
Nishimura, M | 1 |
Kawada, J | 1 |
Matsuura, N | 1 |
Kitagawa, A | 1 |
Nomura, M | 1 |
Okumura, Y | 1 |
Nakatsuka, R | 1 |
Miyazaki, S | 1 |
Danno, K | 1 |
Motoori, M | 1 |
Kubota, M | 1 |
Matsuda, C | 1 |
Fujitani, K | 1 |
Iwase, K | 1 |
Li, H | 2 |
Zhang, Z | 1 |
Zhou, Z | 1 |
Ding, X | 1 |
Zhou, G | 1 |
Zhang, ZY | 1 |
Zhou, ZQ | 1 |
Guan, J | 1 |
Tong, DN | 1 |
Zhou, GW | 1 |
Kuga, Y | 1 |
Moriya, T | 1 |
Fukuda, S | 1 |
Nishida, T | 1 |
Nishiguchi, R | 1 |
Kim, DH | 1 |
Honda, M | 1 |
Miyamoto, A | 1 |
Hama, N | 1 |
Maeda, S | 1 |
Uemura, M | 1 |
Yamamoto, K | 1 |
Miyake, K | 1 |
Nishikawa, K | 1 |
Miyazaki, M | 1 |
Ikeda, M | 2 |
Hirao, M | 1 |
Sekimoto, M | 1 |
Nakamori, S | 1 |
Matsumoto, M | 1 |
Udagawa, I | 1 |
Yasutomi, J | 1 |
Kusashio, K | 1 |
Kasagawa, T | 1 |
Tonooka, T | 1 |
Tashima, Y | 1 |
Irabu, S | 1 |
Nobumoto, D | 1 |
Suzuki, M | 2 |
Fukao, K | 1 |
Morinaga, S | 1 |
Yamamoto, Y | 1 |
Sugano, N | 1 |
Wada, H | 2 |
Shiozawa, M | 1 |
Akaike, M | 1 |
Sugimasa, Y | 1 |
Wakatsuki, T | 1 |
Katsushima, F | 1 |
Monoe, K | 1 |
Kanno, Y | 1 |
Takahashi, A | 1 |
Yokokawa, J | 1 |
Ohira, H | 1 |
Yamada, M | 1 |
Shiroeda, H | 1 |
Shiroeda, S | 1 |
Sato, K | 1 |
Arisawa, T | 1 |
Tsutsumi, M | 1 |
Kadono, K | 1 |
Kawamoto, K | 1 |
Park, T | 1 |
Hatano, H | 1 |
Kobayashi, S | 2 |
Nagano, H | 2 |
Tomokuni, A | 1 |
Murakami, M | 1 |
Marubashi, S | 2 |
Eguchi, H | 2 |
Takeda, Y | 2 |
Tanemura, M | 2 |
Wakasa, K | 1 |
Doki, Y | 2 |
Mori, M | 2 |
Akiyama, N | 1 |
Ayata, S | 1 |
Maruyama, Y | 1 |
Tsukada, Y | 1 |
Umeshita, H | 1 |
Tamura, T | 1 |
Mizuyama, Y | 1 |
Shinto, O | 1 |
Nishihara, T | 1 |
Nakagawa, H | 1 |
Ono, Y | 1 |
Kamo, N | 1 |
Mori, A | 1 |
Nitta, T | 1 |
Hatano, E | 1 |
Mitsuyoshi, H | 1 |
Makino, H | 1 |
Kametaka, H | 1 |
Koyama, T | 1 |
Seike, K | 1 |
Shimizu, J | 1 |
Nagai, K | 1 |
Miyake, M | 1 |
Hata, T | 1 |
Kawanishi, K | 1 |
Fujita, J | 1 |
Kitada, M | 1 |
Shimano, T | 1 |
Suzuki, S | 1 |
Morishita, K | 1 |
Kaji, S | 1 |
Koike, N | 1 |
Takeo, Y | 1 |
Harada, N | 1 |
Hayashi, T | 1 |
Imaizumi, T | 1 |
Nakashima, A | 1 |
Sakabe, R | 1 |
Kobayashi, H | 1 |
Sekine, S | 1 |
Nagata, T | 1 |
Moriyama, M | 1 |
Omura, T | 1 |
Watanabe, T | 1 |
Hori, R | 1 |
Yoshioka, I | 1 |
Sawada, S | 1 |
Fukuoka, J | 1 |
Tsukada, K | 1 |
Tada, S | 1 |
Fujikawa, T | 1 |
Tanaka, A | 1 |
Yoshimoto, Y | 1 |
Maekawa, H | 1 |
Shimoike, N | 1 |
Kawashima, T | 1 |
Shiraishi, K | 1 |
Hanada, N | 1 |
Kusano, S | 1 |
Hori, K | 1 |
Momi, H | 1 |
Ueno, H | 1 |
Mori, Y | 1 |
Katsumata, K | 1 |
Tokita, H | 1 |
Kato, F | 1 |
Yamamoto, J | 1 |
Tsuchida, A | 1 |
Aoki, T | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Endobiliary Radiofrequency Ablation With S-1 in Patients With Unresectable Cholangiocarcinoma: A Prospective Randomized Trial With Open Label Control[NCT02592538] | 66 participants (Actual) | Interventional | 2015-12-31 | Completed | |||
PD-1 Antibody Plus Gemcitabine and Oxaliplatin (GEMOX) as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma Patients With Positively Metastatic Lymph Nodes : a Single Arm, Phase II Trial[NCT05430698] | Phase 2 | 62 participants (Anticipated) | Interventional | 2023-01-31 | Recruiting | ||
Photodynamic Therapy With S-1 in the Patients With Unresectable Type III or IV Cholangiocarcinoma: A Prospective Randomized Trial With Open Label Control[NCT00869635] | Phase 3 | 43 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for oxonic acid and Bile Duct Cancer
Article | Year |
---|---|
[A Distal Bile Duct Carcinoma Patient Who Underwent Surgical Resection for Liver Metastasis].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo | 2018 |
5 trials available for oxonic acid and Bile Duct Cancer
Article | Year |
---|---|
Endoscopic radiofrequency ablation plus a novel oral 5-fluorouracil compound versus radiofrequency ablation alone for unresectable extrahepatic cholangiocarcinoma.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrah | 2020 |
Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy.
Topics: Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplas | 2018 |
Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bile Duct Neopla | 2014 |
Effects of valproic acid in combination with S-1 on advanced pancreatobiliary tract cancers: clinical study phases I/II.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Drug C | 2014 |
Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; CA-19-9 Antigen; D | 2016 |
43 other studies available for oxonic acid and Bile Duct Cancer
Article | Year |
---|---|
[A Case with Three Resections of the Pulmonary Metastases of a Distal Bile Duct Carcinoma].
Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts; Drug Combinations; Humans; L | 2019 |
Treatment of advanced intrahepatic cholangiocarcinoma with sintilimab combined with tegafur-gimeracil-oteracil potassium capsules (S-1): a case report.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplas | 2020 |
A prospective feasibility study of one-year administration of adjuvant S-1 therapy for resected biliary tract cancer in a multi-institutional trial (Tokyo Study Group for Biliary Cancer: TOSBIC01).
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ampulla of Vater; Bile Duct Neoplasms; Carcino | 2020 |
Characterization of Prognostic Factors and the Efficacy of Adjuvant S-1 Chemotherapy in Patients with Post-surgery Extrahepatic Bile Duct Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; | 2017 |
Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biomarkers, Tumor; Cell N | 2018 |
Gallbladder cancer with tumor thrombus in the portal vein: A case report.
Topics: Administration, Intravenous; Antineoplastic Agents; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; D | 2018 |
Orotate phosphoribosyltransferase as a predictor of benefit from S-1 adjuvant chemotherapy for cholangiocarcinoma patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biomarkers, Tumor; Chemot | 2019 |
The Efficacy and Limitations of Postoperative Adjuvant Chemotherapy in Patients With Extrahepatic Cholangiocarcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biliary Tract Surgical Pr | 2019 |
[A case of inoperable advanced bile duct cancer treated effectively with combined chemotherapy of gemcitabine and S-1].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Chemoradiotherapy; Deoxycytidin | 2013 |
Perineural invasion in extrahepatic cholangiocarcinoma: prognostic impact and treatment strategies.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; | 2013 |
Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bile Duct Neoplasms; Cell Cultur | 2013 |
Proton beam therapy for unresectable intrahepatic cholangiocarcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; | 2015 |
[A long term survival case of hilar cholangiocarcinoma with multiple metastases treated with chemotherapy and operation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cathe | 2014 |
[A case of intrahepatic cholangiocarcinoma with peritoneal dissemination treated successfully with surgical resection and adjuvant chemotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chemotherapy, | 2014 |
[Six-year survival with recurrent intrahepatic cholangiocarcinoma achieved by simple S-1 administration].
Topics: Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocel | 2015 |
[Long Term Survival in a Case of Hilar Cholangiocarcinoma Treated with Chemotherapy and Surgery].
Topics: Aged; Antineoplastic Agents; Bile Duct Neoplasms; Cholangiocarcinoma; Combined Modality Therapy; Deo | 2015 |
[A Patient with Three-Year Relapse-Free Survival after Surgical Resection for Lung and Liver Metastases of Cholangiocarcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocarcinoma; Deoxycytidi | 2015 |
[A Case of Local Recurrence of Bile Duct Cancer Completely Responding to Chemoradiotherapy with S-1].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Chemoradiotherapy; Drug Com | 2015 |
[A Three-Year Survival Case of Extrahepatic Cholangiocarcinoma Treated with Palliative Bile Duct Resection and S-1 Monotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Cholangiocarci | 2015 |
[A Case of Resected Gastric Cancer Occurring Simultaneously with Intrahepatic Cholangiocarcinoma after S-1 plus Cisplatin Chemotherapy].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocar | 2015 |
Optimal combination of gemcitabine, sorafenib, and S-1 shows increased efficacy in treating cholangiocarcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cell Line, Tumor; Chol | 2016 |
[Resection of Advanced Intrahepatic Cholangiocarcinoma after an Effective Response to S-1 and Gemcitabine Combination Therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocarcinoma; Deoxy | 2016 |
Squamous cell carcinoma of the extrahepatic bile duct with metachronous para-aortic lymph node metastasis successfully treated with S-1 plus cisplatin.
Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Carcinoma, Squ | 2016 |
[A Case of Lymph Node Metastasis of Intrahepatic Bile Duct Cancer Successfully Treated Using Multidisciplinary Therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; | 2016 |
[A case of liver metastatic recurrence of bile duct cancer completely responding to single-drug S-1 chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biomarkers, Tumor; Drug C | 2008 |
Long-term survival after multimodal therapy in a patient demonstrating intrahepatic cholangiocarcinoma with hilar invasion and intrahepatic metastases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic | 2008 |
A case of advanced intrahepatic cholangiocarcinoma successfully treated with chemosensitivity test-guided systemic chemotherapy.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo | 2009 |
Cholangiocarcinoma producing parathyroid hormone-related peptide treated with chemoradiation using gemcitabine and S-1.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic | 2009 |
[A case of cancer successfully treated by chemotherapy of S-1 as first-line chemotherapy].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Drug Combinations; Humans; | 2009 |
[A case of successful multimodal treatment for combined hepatocellular and cholangiocarcinoma with portal venous tumor thrombus].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2009 |
[Response in a case of inoperable bile duct cancer treated by combined chemotherapy of S-1 and gemcitabine].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Deoxycytidine; Drug Combination | 2010 |
[A case report--intrahepatic arterial infusion with CDDP and S-1 administration can elicit long-term survival for the patient with recurrenced intrahepatic cholangiocarcinoma after resection].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2010 |
[A long-term survival case of unresectable intrahepatic cholangiocarcinoma treated with chemotherapy].
Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, | 2010 |
[Two cases of curatively resected intrahepatic cholangiocellular carcinomas through effective response to neoadjuvant chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; | 2011 |
[A case of long-term survival of a patient with intrahepatic bile duct cancer and early nodal recurrence who responded to S-1 therapy].
Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Drug Combinati | 2011 |
[A case of intrahepatic recurrence of intrahepatic cholangiocarcinoma treated with repeated hepatectomy].
Topics: Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; | 2011 |
[A case of bile duct cancer with positive surgical margin obtaining long-term survival after S-1 monotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Combined Modality Therapy; Drug Combinat | 2012 |
Adjuvant chemotherapy with gemcitabine and S-1 after surgical resection for advanced biliary carcinoma: outcomes and prognostic factors.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, In | 2012 |
Prognostic significance of aquaporins in human biliary tract carcinoma.
Topics: Aged; Aged, 80 and over; Aquaporin 1; Aquaporin 4; Aquaporin 5; Aquaporins; Bile Duct Neoplasms; Bio | 2012 |
[A case of unresectable hilar cholangiocarcinoma successfully treated by gemcitabine and S-1 combination chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chola | 2012 |
[Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; | 2007 |
[Two cases of advanced extrahepatic bile duct cancer successfully treated by S-1 monotherapy].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Drug | 2007 |
[A case of recurrence after resection of stage IV advanced bile duct cancer responding well to S-1/cisplatin combination chemotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2007 |