Page last updated: 2024-11-02

oxonic acid and Bile Duct Cancer

oxonic acid has been researched along with Bile Duct Cancer in 49 studies

Oxonic Acid: Antagonist of urate oxidase.

Research Excerpts

ExcerptRelevanceReference
"Although the combination of cisplatin and gemcitabine (GEM) is considered the standard first-line chemotherapy against unresectable hilar cholangiocarcinoma (HC), its efficacy is discouraging."9.22Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial. ( Guan, J; Li, H; Tong, DN; Zhang, ZY; Zhou, GW; Zhou, ZQ, 2016)
"The aim of this study was to investigate the prognostic significance of HuR in cholangiocarcinoma patients who received adjuvant gemcitabine-based chemotherapy (AGC) after surgical resection."7.88Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy. ( Kondo, N; Murakami, Y; Nakagawa, N; Sueda, T; Takahashi, S; Toyota, K; Uemura, K, 2018)
"We report curative resection of an advanced intrahepatic cholangiocarcinoma that responded well to combined S-1 and gemcitabine chemotherapy(GS therapy)."7.83[Resection of Advanced Intrahepatic Cholangiocarcinoma after an Effective Response to S-1 and Gemcitabine Combination Therapy]. ( Fukuda, S; Kuga, Y; Moriya, T; Nishida, T, 2016)
" A 66-year-old male treated with combined paclitaxel (PTX) and S-1 suffered from ARDS following neutropenia."7.74[Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma]. ( Hanada, N; Hori, K; Kusano, S; Momi, H, 2007)
"Hilar cholangiocarcinoma is an uncommon cancer and its overall incidence is increasing."6.79Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma. ( Choi, HJ; Choi, JH; Eum, JB; Jang, JW; Kim, HJ; Kim, MH; Lee, JB; Lee, JL; Lee, SK; Lee, SS; Park, DH; Park, SE; Seo, DW, 2014)
"Advanced intrahepatic cholangiocarcinoma (ICC) is a highly challenging malignancy characterized by rapid progression and poor prognosis."5.56Treatment of advanced intrahepatic cholangiocarcinoma with sintilimab combined with tegafur-gimeracil-oteracil potassium capsules (S-1): a case report. ( Cao, L; Li, S; Liu, J; Wang, C, 2020)
"Simvastatin has inhibitory effects on cancers."5.39Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism. ( Cai, JP; Chen, W; Hao, XY; Hou, X; Liang, LJ; Yin, XY, 2013)
"Although the combination of cisplatin and gemcitabine (GEM) is considered the standard first-line chemotherapy against unresectable hilar cholangiocarcinoma (HC), its efficacy is discouraging."5.22Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial. ( Guan, J; Li, H; Tong, DN; Zhang, ZY; Zhou, GW; Zhou, ZQ, 2016)
"The aim of this study was to investigate the prognostic significance of HuR in cholangiocarcinoma patients who received adjuvant gemcitabine-based chemotherapy (AGC) after surgical resection."3.88Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy. ( Kondo, N; Murakami, Y; Nakagawa, N; Sueda, T; Takahashi, S; Toyota, K; Uemura, K, 2018)
"We report curative resection of an advanced intrahepatic cholangiocarcinoma that responded well to combined S-1 and gemcitabine chemotherapy(GS therapy)."3.83[Resection of Advanced Intrahepatic Cholangiocarcinoma after an Effective Response to S-1 and Gemcitabine Combination Therapy]. ( Fukuda, S; Kuga, Y; Moriya, T; Nishida, T, 2016)
" A 66-year-old male treated with combined paclitaxel (PTX) and S-1 suffered from ARDS following neutropenia."3.74[Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma]. ( Hanada, N; Hori, K; Kusano, S; Momi, H, 2007)
"Patients with pancreatic cancer commonly suffer from exocrine pancreatic insufficiency, and the ingestion of digestive enzyme supplements may improve absorption."2.87Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy. ( Abe, K; Gocho, T; Haruki, K; Onda, S; Sakamoto, T; Takano, Y; Uwagawa, T; Yanaga, K, 2018)
"Hilar cholangiocarcinoma is an uncommon cancer and its overall incidence is increasing."2.79Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma. ( Choi, HJ; Choi, JH; Eum, JB; Jang, JW; Kim, HJ; Kim, MH; Lee, JB; Lee, JL; Lee, SK; Lee, SS; Park, DH; Park, SE; Seo, DW, 2014)
"Advanced intrahepatic cholangiocarcinoma (ICC) is a highly challenging malignancy characterized by rapid progression and poor prognosis."1.56Treatment of advanced intrahepatic cholangiocarcinoma with sintilimab combined with tegafur-gimeracil-oteracil potassium capsules (S-1): a case report. ( Cao, L; Li, S; Liu, J; Wang, C, 2020)
"In our case, we report a gallbladder cancer with portal vein thrombus."1.48Gallbladder cancer with tumor thrombus in the portal vein: A case report. ( Bai, XL; Chen, W; Liang, TB; Ma, T; Tu, JJ; Zhang, XZ, 2018)
"Treatment for unresectable intrahepatic cholangiocarcinoma (ICC) has not been established."1.42Proton beam therapy for unresectable intrahepatic cholangiocarcinoma. ( Abei, M; Fukuda, K; Hashimoto, T; Ishikawa, H; Mizumoto, M; Ohkawa, A; Okumura, T; Sakae, T; Sakurai, H; Tsuboi, K, 2015)
"The tumor was diagnosed as hepatocellular carcinoma by MRI and CT."1.42[Six-year survival with recurrent intrahepatic cholangiocarcinoma achieved by simple S-1 administration]. ( Hirose, T; Ishikawa, Y; Kitamura, K; Miki, A; Minami, T; Morioka, H; Nishihira, T; Otani, T; Suzuki, T; Yoshitani, S, 2015)
"An 80-year-old man with common bile duct cancer was treated by pancreaticoduodenectomy with D2 lymph node dissection in October 2005."1.42[A Case of Local Recurrence of Bile Duct Cancer Completely Responding to Chemoradiotherapy with S-1]. ( Hishikawa, H; Matsuura, T; Ozaki, T; Saito, T; Sakaguchi, T; Sueyoshi, H; Tanaka, Y; Ueda, A; Yamamichi, K, 2015)
"We encountered a case of resected gastric cancer, which occurred concomitantly with intrahepatic cholangiocarcinoma after S-1 plus cisplatin chemotherapy, in a patient who was previously diagnosed with metastatic liver tumor before treatment."1.42[A Case of Resected Gastric Cancer Occurring Simultaneously with Intrahepatic Cholangiocarcinoma after S-1 plus Cisplatin Chemotherapy]. ( Danno, K; Fujitani, K; Iwase, K; Kawada, J; Kitagawa, A; Kubota, M; Matsuda, C; Matsuura, N; Miyazaki, S; Motoori, M; Nakatsuka, R; Nishimura, M; Nomura, M; Okumura, Y, 2015)
"Medical records of 133 patients with extrahepatic cholangiocarcinoma who underwent curative resection were reviewed retrospectively."1.39Perineural invasion in extrahepatic cholangiocarcinoma: prognostic impact and treatment strategies. ( Hashimoto, Y; Kondo, N; Murakami, Y; Muto, T; Nakagawa, N; Sasaki, H; Sudo, T; Sueda, T; Uemura, K; Urabe, K, 2013)
"Simvastatin has inhibitory effects on cancers."1.39Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism. ( Cai, JP; Chen, W; Hao, XY; Hou, X; Liang, LJ; Yin, XY, 2013)
"We report a case of bile duct cancer with a positive surgical margin obtaining long-term survival after S-1 monotherapy."1.38[A case of bile duct cancer with positive surgical margin obtaining long-term survival after S-1 monotherapy]. ( Harada, N; Hayashi, T; Imaizumi, T; Kaji, S; Koike, N; Morishita, K; Suzuki, M; Suzuki, S; Takeo, Y, 2012)
"Computed tomography showed nodal recurrence 6 months after surgery."1.37[A case of long-term survival of a patient with intrahepatic bile duct cancer and early nodal recurrence who responded to S-1 therapy]. ( Kametaka, H; Koyama, T; Makino, H; Seike, K, 2011)
"A 60-year-old man with intrahepatic cholangiocarcinoma (ICC) underwent a left hepatectomy."1.37[A case of intrahepatic recurrence of intrahepatic cholangiocarcinoma treated with repeated hepatectomy]. ( Akagi, K; Dono, K; Fujita, J; Hata, T; Ikeda, K; Iwazawa, T; Kawanishi, K; Kitada, M; Miyake, M; Nagai, K; Shimano, T; Shimizu, J, 2011)
"To cure intrahepatic cholangiocarcinoma (ICC), only a surgical resection is the potential treatment at present."1.36[A case report--intrahepatic arterial infusion with CDDP and S-1 administration can elicit long-term survival for the patient with recurrenced intrahepatic cholangiocarcinoma after resection]. ( Doki, Y; Eguchi, H; Kobayashi, S; Marubashi, S; Mori, M; Nagano, H; Takeda, Y; Tanemura, M; Tanida, T; Umeshita, H; Wada, H, 2010)
"Gemcitabine was administered once a week for 3 weeks followed by a week rest."1.36[A long-term survival case of unresectable intrahepatic cholangiocarcinoma treated with chemotherapy]. ( Mizuyama, Y; Nakagawa, H; Nishihara, T; Ono, Y; Shinto, O; Tamura, T, 2010)
"A 65-year-old man with common bile duct cancer was treated by pylorus-preserving pancreaticoduodenectomy with D2 lymph node dissection."1.35[A case of liver metastatic recurrence of bile duct cancer completely responding to single-drug S-1 chemotherapy]. ( Fukao, K; Irabu, S; Kasagawa, T; Kusashio, K; Matsumoto, M; Nobumoto, D; Suzuki, M; Tashima, Y; Tonooka, T; Udagawa, I; Yasutomi, J, 2008)
"Cholangiocarcinoma is a therapeutically challenging malignancy."1.35Long-term survival after multimodal therapy in a patient demonstrating intrahepatic cholangiocarcinoma with hilar invasion and intrahepatic metastases. ( Akaike, M; Morinaga, S; Shiozawa, M; Sugano, N; Sugimasa, Y; Wada, H; Yamamoto, Y, 2008)
"A 66-year-old man was diagnosed with hepatocellular carcinoma with Vp3 by abdominal enhanced CT."1.35[A case of successful multimodal treatment for combined hepatocellular and cholangiocarcinoma with portal venous tumor thrombus]. ( Doki, Y; Eguchi, H; Hatano, H; Kobayashi, S; Marubashi, S; Mori, M; Murakami, M; Nagano, H; Takeda, Y; Tanemura, M; Tomimaru, Y; Tomokuni, A; Wakasa, K, 2009)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (18.37)29.6817
2010's37 (75.51)24.3611
2020's3 (6.12)2.80

Authors

AuthorsStudies
Ando, K1
Tomimaru, Y2
Iwazawa, T2
Noguchi, K1
Nagase, H1
Ogino, T1
Hirota, M1
Oshima, K1
Tanida, T2
Noura, S1
Kawase, T1
Imamura, H1
Akagi, K2
Dono, K2
Liu, J1
Wang, C1
Cao, L1
Li, S1
Yang, J1
Wang, J1
Zhou, H1
Wang, Y1
Huang, H1
Jin, H1
Lou, Q1
Shah, RJ1
Zhang, X1
Itano, O1
Takemura, Y1
Kishida, N1
Tamagawa, E1
Shinozaki, H1
Ikeda, K3
Urakami, H1
Ei, S1
Hayatsu, S1
Suzuki, K1
Sakuragawa, T1
Ishii, M1
Shito, M1
Aiura, K1
Fujisaki, H1
Takano, K1
Matsui, J1
Minagawa, T1
Shinoda, M1
Kitago, M1
Abe, Y1
Yagi, H1
Oshima, G1
Hori, S1
Kitagawa, Y1
Okabayashi, T1
Shima, Y1
Iwata, J1
Morita, S1
Sumiyoshi, T1
Sui, K1
Shimada, Y2
Iiyama, T1
Toyota, K1
Murakami, Y3
Kondo, N3
Uemura, K3
Nakagawa, N3
Takahashi, S1
Sueda, T3
Abe, K2
Uwagawa, T1
Haruki, K1
Takano, Y1
Onda, S1
Sakamoto, T2
Gocho, T1
Yanaga, K1
Komiyama, S1
Izumiya, Y1
Kimura, Y1
Nakashima, S1
Kin, S1
Kawakami, S1
Zhang, XZ1
Tu, JJ1
Chen, W2
Ma, T1
Bai, XL1
Liang, TB1
Akahoshi, K1
Ban, D1
Kuboki, R1
Oba, A1
Ono, H1
Mitsunori, Y1
Kudo, A1
Tanaka, S1
Tanabe, M1
Morino, K1
Seo, S1
Yoh, T1
Nishino, H1
Yamanaka, K1
Fukumitsu, K1
Ishii, T1
Taura, K1
Okajima, H1
Kaido, T1
Uemoto, S2
Horie, S1
Ayaki, M1
Kashiwagi, R1
Mitsuda, A1
Tanaka, H2
Sudo, T2
Hashimoto, Y2
Muto, T1
Sasaki, H1
Urabe, K1
Cai, JP1
Hou, X1
Liang, LJ1
Hao, XY1
Yin, XY1
Park, DH1
Lee, SS1
Park, SE1
Lee, JL1
Choi, JH1
Choi, HJ1
Jang, JW1
Kim, HJ1
Eum, JB1
Seo, DW1
Lee, SK1
Kim, MH1
Lee, JB1
Iwahashi, S1
Utsunomiya, T1
Imura, S1
Morine, Y1
Ikemoto, T1
Arakawa, Y1
Saito, Y1
Ishikawa, D1
Shimada, M1
Ohkawa, A1
Mizumoto, M1
Ishikawa, H1
Abei, M1
Fukuda, K1
Hashimoto, T1
Sakae, T1
Tsuboi, K1
Okumura, T2
Sakurai, H1
Shirasaki, K1
Morikawa, T2
Otsuka, H1
Katayose, Y1
Unno, M2
Shiozaki, S1
Satoh, D1
Matsukawa, H1
Yamaguchi, K1
Takahashi, K1
Mimura, N1
Taguchi, K1
Araki, H1
Toshima, T1
Kato, T1
Miyake, S1
Miyoshi, H1
Yoshida, K1
Choda, Y1
Tokumoto, N1
Kanazawa, T1
Harano, M1
Ojima, Y1
Idani, H1
Okajima, M1
Ninomiya, M1
Miki, A1
Hirose, T1
Minami, T1
Morioka, H1
Suzuki, T1
Otani, T1
Kitamura, K1
Yoshitani, S1
Ishikawa, Y1
Nishihira, T1
Kanomata, H1
Seyama, Y1
Tani, K1
Tanizawa, T1
Warabi, M1
Murayama, M1
Asano, T1
Takahashi, M1
Matsuoka, Y1
Miyamoto, Y1
Umekita, N1
Aoki, S1
Mizuma, M1
Oyauchi, M1
Yoshida, H1
Okada, R1
Abe, T2
Sakata, N1
Nakagawa, K1
Hayashi, H1
Motoi, F1
Naitoh, T1
Okada, Y1
Yamamichi, K1
Sueyoshi, H1
Tanaka, Y1
Sakaguchi, T1
Hishikawa, H1
Ueda, A1
Matsuura, T1
Ozaki, T1
Saito, T1
Fushimi, K1
Omori, T1
Nishimura, M1
Kawada, J1
Matsuura, N1
Kitagawa, A1
Nomura, M1
Okumura, Y1
Nakatsuka, R1
Miyazaki, S1
Danno, K1
Motoori, M1
Kubota, M1
Matsuda, C1
Fujitani, K1
Iwase, K1
Li, H2
Zhang, Z1
Zhou, Z1
Ding, X1
Zhou, G1
Zhang, ZY1
Zhou, ZQ1
Guan, J1
Tong, DN1
Zhou, GW1
Kuga, Y1
Moriya, T1
Fukuda, S1
Nishida, T1
Nishiguchi, R1
Kim, DH1
Honda, M1
Miyamoto, A1
Hama, N1
Maeda, S1
Uemura, M1
Yamamoto, K1
Miyake, K1
Nishikawa, K1
Miyazaki, M1
Ikeda, M2
Hirao, M1
Sekimoto, M1
Nakamori, S1
Matsumoto, M1
Udagawa, I1
Yasutomi, J1
Kusashio, K1
Kasagawa, T1
Tonooka, T1
Tashima, Y1
Irabu, S1
Nobumoto, D1
Suzuki, M2
Fukao, K1
Morinaga, S1
Yamamoto, Y1
Sugano, N1
Wada, H2
Shiozawa, M1
Akaike, M1
Sugimasa, Y1
Wakatsuki, T1
Katsushima, F1
Monoe, K1
Kanno, Y1
Takahashi, A1
Yokokawa, J1
Ohira, H1
Yamada, M1
Shiroeda, H1
Shiroeda, S1
Sato, K1
Arisawa, T1
Tsutsumi, M1
Kadono, K1
Kawamoto, K1
Park, T1
Hatano, H1
Kobayashi, S2
Nagano, H2
Tomokuni, A1
Murakami, M1
Marubashi, S2
Eguchi, H2
Takeda, Y2
Tanemura, M2
Wakasa, K1
Doki, Y2
Mori, M2
Akiyama, N1
Ayata, S1
Maruyama, Y1
Tsukada, Y1
Umeshita, H1
Tamura, T1
Mizuyama, Y1
Shinto, O1
Nishihara, T1
Nakagawa, H1
Ono, Y1
Kamo, N1
Mori, A1
Nitta, T1
Hatano, E1
Mitsuyoshi, H1
Makino, H1
Kametaka, H1
Koyama, T1
Seike, K1
Shimizu, J1
Nagai, K1
Miyake, M1
Hata, T1
Kawanishi, K1
Fujita, J1
Kitada, M1
Shimano, T1
Suzuki, S1
Morishita, K1
Kaji, S1
Koike, N1
Takeo, Y1
Harada, N1
Hayashi, T1
Imaizumi, T1
Nakashima, A1
Sakabe, R1
Kobayashi, H1
Sekine, S1
Nagata, T1
Moriyama, M1
Omura, T1
Watanabe, T1
Hori, R1
Yoshioka, I1
Sawada, S1
Fukuoka, J1
Tsukada, K1
Tada, S1
Fujikawa, T1
Tanaka, A1
Yoshimoto, Y1
Maekawa, H1
Shimoike, N1
Kawashima, T1
Shiraishi, K1
Hanada, N1
Kusano, S1
Hori, K1
Momi, H1
Ueno, H1
Mori, Y1
Katsumata, K1
Tokita, H1
Kato, F1
Yamamoto, J1
Tsuchida, A1
Aoki, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Endobiliary Radiofrequency Ablation With S-1 in Patients With Unresectable Cholangiocarcinoma: A Prospective Randomized Trial With Open Label Control[NCT02592538]66 participants (Actual)Interventional2015-12-31Completed
PD-1 Antibody Plus Gemcitabine and Oxaliplatin (GEMOX) as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma Patients With Positively Metastatic Lymph Nodes : a Single Arm, Phase II Trial[NCT05430698]Phase 262 participants (Anticipated)Interventional2023-01-31Recruiting
Photodynamic Therapy With S-1 in the Patients With Unresectable Type III or IV Cholangiocarcinoma: A Prospective Randomized Trial With Open Label Control[NCT00869635]Phase 343 participants (Actual)Interventional2009-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for oxonic acid and Bile Duct Cancer

ArticleYear
[A Distal Bile Duct Carcinoma Patient Who Underwent Surgical Resection for Liver Metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo

2018

Trials

5 trials available for oxonic acid and Bile Duct Cancer

ArticleYear
Endoscopic radiofrequency ablation plus a novel oral 5-fluorouracil compound versus radiofrequency ablation alone for unresectable extrahepatic cholangiocarcinoma.
    Gastrointestinal endoscopy, 2020, Volume: 92, Issue:6

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrah

2020
Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy.
    Anticancer research, 2018, Volume: 38, Issue:4

    Topics: Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplas

2018
Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:7

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bile Duct Neopla

2014
Effects of valproic acid in combination with S-1 on advanced pancreatobiliary tract cancers: clinical study phases I/II.
    Anticancer research, 2014, Volume: 34, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Drug C

2014
Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial.
    Oncotarget, 2016, May-03, Volume: 7, Issue:18

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; CA-19-9 Antigen; D

2016

Other Studies

43 other studies available for oxonic acid and Bile Duct Cancer

ArticleYear
[A Case with Three Resections of the Pulmonary Metastases of a Distal Bile Duct Carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:13

    Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts; Drug Combinations; Humans; L

2019
Treatment of advanced intrahepatic cholangiocarcinoma with sintilimab combined with tegafur-gimeracil-oteracil potassium capsules (S-1): a case report.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplas

2020
A prospective feasibility study of one-year administration of adjuvant S-1 therapy for resected biliary tract cancer in a multi-institutional trial (Tokyo Study Group for Biliary Cancer: TOSBIC01).
    BMC cancer, 2020, Jul-23, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ampulla of Vater; Bile Duct Neoplasms; Carcino

2020
Characterization of Prognostic Factors and the Efficacy of Adjuvant S-1 Chemotherapy in Patients with Post-surgery Extrahepatic Bile Duct Cancer.
    Anticancer research, 2017, Volume: 37, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms;

2017
Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy.
    Annals of surgical oncology, 2018, Volume: 25, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biomarkers, Tumor; Cell N

2018
Gallbladder cancer with tumor thrombus in the portal vein: A case report.
    Medicine, 2018, Volume: 97, Issue:16

    Topics: Administration, Intravenous; Antineoplastic Agents; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; D

2018
Orotate phosphoribosyltransferase as a predictor of benefit from S-1 adjuvant chemotherapy for cholangiocarcinoma patients.
    Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biomarkers, Tumor; Chemot

2019
The Efficacy and Limitations of Postoperative Adjuvant Chemotherapy in Patients With Extrahepatic Cholangiocarcinoma.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biliary Tract Surgical Pr

2019
[A case of inoperable advanced bile duct cancer treated effectively with combined chemotherapy of gemcitabine and S-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Chemoradiotherapy; Deoxycytidin

2013
Perineural invasion in extrahepatic cholangiocarcinoma: prognostic impact and treatment strategies.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2013, Volume: 17, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms;

2013
Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism.
    Anti-cancer drugs, 2013, Volume: 24, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bile Duct Neoplasms; Cell Cultur

2013
Proton beam therapy for unresectable intrahepatic cholangiocarcinoma.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms;

2015
[A long term survival case of hilar cholangiocarcinoma with multiple metastases treated with chemotherapy and operation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cathe

2014
[A case of intrahepatic cholangiocarcinoma with peritoneal dissemination treated successfully with surgical resection and adjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chemotherapy,

2014
[Six-year survival with recurrent intrahepatic cholangiocarcinoma achieved by simple S-1 administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:5

    Topics: Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocel

2015
[Long Term Survival in a Case of Hilar Cholangiocarcinoma Treated with Chemotherapy and Surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged; Antineoplastic Agents; Bile Duct Neoplasms; Cholangiocarcinoma; Combined Modality Therapy; Deo

2015
[A Patient with Three-Year Relapse-Free Survival after Surgical Resection for Lung and Liver Metastases of Cholangiocarcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocarcinoma; Deoxycytidi

2015
[A Case of Local Recurrence of Bile Duct Cancer Completely Responding to Chemoradiotherapy with S-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Chemoradiotherapy; Drug Com

2015
[A Three-Year Survival Case of Extrahepatic Cholangiocarcinoma Treated with Palliative Bile Duct Resection and S-1 Monotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Cholangiocarci

2015
[A Case of Resected Gastric Cancer Occurring Simultaneously with Intrahepatic Cholangiocarcinoma after S-1 plus Cisplatin Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocar

2015
Optimal combination of gemcitabine, sorafenib, and S-1 shows increased efficacy in treating cholangiocarcinoma in vitro and in vivo.
    Anti-cancer drugs, 2016, Volume: 27, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cell Line, Tumor; Chol

2016
[Resection of Advanced Intrahepatic Cholangiocarcinoma after an Effective Response to S-1 and Gemcitabine Combination Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocarcinoma; Deoxy

2016
Squamous cell carcinoma of the extrahepatic bile duct with metachronous para-aortic lymph node metastasis successfully treated with S-1 plus cisplatin.
    BMJ case reports, 2016, Dec-08, Volume: 2016

    Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Carcinoma, Squ

2016
[A Case of Lymph Node Metastasis of Intrahepatic Bile Duct Cancer Successfully Treated Using Multidisciplinary Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic;

2016
[A case of liver metastatic recurrence of bile duct cancer completely responding to single-drug S-1 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Biomarkers, Tumor; Drug C

2008
Long-term survival after multimodal therapy in a patient demonstrating intrahepatic cholangiocarcinoma with hilar invasion and intrahepatic metastases.
    International journal of clinical oncology, 2008, Volume: 13, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic

2008
A case of advanced intrahepatic cholangiocarcinoma successfully treated with chemosensitivity test-guided systemic chemotherapy.
    World journal of gastroenterology, 2009, Nov-07, Volume: 15, Issue:41

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo

2009
Cholangiocarcinoma producing parathyroid hormone-related peptide treated with chemoradiation using gemcitabine and S-1.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:24

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic

2009
[A case of cancer successfully treated by chemotherapy of S-1 as first-line chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:13

    Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Drug Combinations; Humans;

2009
[A case of successful multimodal treatment for combined hepatocellular and cholangiocarcinoma with portal venous tumor thrombus].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2009
[Response in a case of inoperable bile duct cancer treated by combined chemotherapy of S-1 and gemcitabine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Deoxycytidine; Drug Combination

2010
[A case report--intrahepatic arterial infusion with CDDP and S-1 administration can elicit long-term survival for the patient with recurrenced intrahepatic cholangiocarcinoma after resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2010
[A long-term survival case of unresectable intrahepatic cholangiocarcinoma treated with chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts,

2010
[Two cases of curatively resected intrahepatic cholangiocellular carcinomas through effective response to neoadjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic;

2011
[A case of long-term survival of a patient with intrahepatic bile duct cancer and early nodal recurrence who responded to S-1 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Drug Combinati

2011
[A case of intrahepatic recurrence of intrahepatic cholangiocarcinoma treated with repeated hepatectomy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma;

2011
[A case of bile duct cancer with positive surgical margin obtaining long-term survival after S-1 monotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Combined Modality Therapy; Drug Combinat

2012
Adjuvant chemotherapy with gemcitabine and S-1 after surgical resection for advanced biliary carcinoma: outcomes and prognostic factors.
    Journal of hepato-biliary-pancreatic sciences, 2012, Volume: 19, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, In

2012
Prognostic significance of aquaporins in human biliary tract carcinoma.
    Oncology reports, 2012, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Aquaporin 1; Aquaporin 4; Aquaporin 5; Aquaporins; Bile Duct Neoplasms; Bio

2012
[A case of unresectable hilar cholangiocarcinoma successfully treated by gemcitabine and S-1 combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chola

2012
[Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic;

2007
[Two cases of advanced extrahepatic bile duct cancer successfully treated by S-1 monotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Drug

2007
[A case of recurrence after resection of stage IV advanced bile duct cancer responding well to S-1/cisplatin combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:9

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2007