Page last updated: 2024-11-02

oxonic acid and Anorexia

oxonic acid has been researched along with Anorexia in 49 studies

Oxonic Acid: Antagonist of urate oxidase.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"A combination of irinotecan with continuous intravenous infusions of 5-fluorouracil (5-FU) and leucovorin (LV) is often used to treat advanced colorectal cancer."9.12Phase II study of combination therapy with S-1 and irinotecan in patients with advanced colorectal cancer. ( Goto, A; Hamaguchi, T; Kato, K; Muro, K; Shimada, Y; Shirao, K; Yamada, Y; Yasui, H, 2006)
"Nausea was improved in the next morning, and the patient ate almost all of his breakfast."5.38[Low-dose mirtazapine improved nausea and appetite loss during S-1 therapy]. ( Imai, E; Ito, T; Nishimura, D; Shibahara, H; Uematsu, N, 2012)
"A combination of irinotecan with continuous intravenous infusions of 5-fluorouracil (5-FU) and leucovorin (LV) is often used to treat advanced colorectal cancer."5.12Phase II study of combination therapy with S-1 and irinotecan in patients with advanced colorectal cancer. ( Goto, A; Hamaguchi, T; Kato, K; Muro, K; Shimada, Y; Shirao, K; Yamada, Y; Yasui, H, 2006)
" Major toxicities were leukopenia (38%), anorexia (27%), increased total bilirubin concentration (25%) and diarrhea (24%)."5.10[Efficacy and safety of novel oral fluoropyrimidine anticancer drug, TS-1 for advanced and recurrent gastric cancer patients]. ( Arai, K; Honma, S; Iwasaki, Y; Kimura, Y; Takahashi, K; Takahashi, T; Yamaguchi, T, 2003)
"A combination therapy of irinotecan hydrochloride (CPT-11) with continuous intravenous infusions of (infusional) 5-fluorouracil (5-FU) and Leucovorin (LV) is often used to treat advanced colorectal cancer."4.83[The current evidence of S-1 and irinotecan hydrochloride combination chemotherapy with tri-weekly schedule]. ( Goto, A, 2006)
"Patients with stage III gastric cancer who underwent D2 gastrectomy were enrolled."3.01Phase II feasibility study of adjuvant chemotherapy with docetaxel/cisplatin/S-1 followed by S-1 for stage III gastric cancer. ( Hirahara, N; Hyakudomi, R; Ishitobi, K; Kaji, S; Matsubara, T; Tajima, Y; Takai, K; Uchida, Y; Yamamoto, T, 2021)
"The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy."2.79Sequential paclitaxel followed by tegafur and uracil (UFT) or S-1 versus UFT or S-1 monotherapy as adjuvant chemotherapy for T4a/b gastric cancer (SAMIT): a phase 3 factorial randomised controlled trial. ( Buyse, M; Fukushima, R; Hara, A; Imamura, H; Kobayashi, M; Kojima, H; Miyashita, Y; Morita, S; Nishikawa, K; Nozaki, I; Oba, K; Sakamoto, J; Takahashi, M; Takahashi, N; Takiguchi, N; Tanabe, K; Tatsumoto, N; Tsuburaya, A; Yoshida, K; Yoshino, S, 2014)
"Gemcitabine was administered at an escalating dose of 600, 800 and 1,000 mg/m(2) over 30 min on day 1, and oral S-1 at a dose of 40 mg/m(2) twice daily and oral leucovorin at a dose of 25 mg twice daily on days 1-7, every 2 weeks."2.79A phase I trial of gemcitabine, S-1 and LV combination (GSL) therapy in advanced pancreatic cancer. ( Hamada, T; Hirano, K; Ijichi, H; Isayama, H; Kogure, H; Koike, K; Miyabayashi, K; Mizuno, S; Mohri, D; Nakai, Y; Saito, K; Sasaki, T; Tada, M; Takahara, N; Tateishi, K; Yamamoto, K; Yamamoto, N, 2014)
" The experimental arm's dosage schedule was paclitaxel 60 mg/m2 (intravenous infusion) on days 1, 8 and 15 and S-1 80-120 mg/d (oral administration) on days 1-14."2.78A multicentre randomised trial comparing weekly paclitaxel + S-1 with weekly paclitaxel + 5-fluorouracil for patients with advanced gastric cancer. ( Ba, Y; Deng, T; Guo, Z; Hu, C; Huang, D; Meng, J; Wan, H; Wang, M; Xiong, J; Xu, N; Yan, Z; Yao, Y; Yu, Z; Zhang, Y; Zheng, R; Zhuang, Z, 2013)
"Gemcitabine was administered at a dose of 1000 mg/m(2) over 30 min on days 1 and 8, and oral S-1 at a dose of 40 mg/m(2) twice daily from days 1 to 14, repeated every 3 weeks."2.76Multicenter phase II study of gemcitabine and S-1 combination therapy (GS Therapy) in patients with metastatic pancreatic cancer. ( Boku, N; Funakoshi, A; Furuse, J; Moriyasu, F; Nakamori, S; Ohkawa, S; Okusaka, T; Sato, T; Tanaka, K; Ueno, H; Yamao, K; Yokosuka, O, 2011)
"Patients with histological proof of prostate cancer refractory to hormonal therapies were eligible."2.75Efficacy of S-1 in patients with castration-resistant prostate cancer: a phase II study. ( Akaza, H; Fujimoto, H; Ikemoto, I; Kobayashi, M; Naito, S; Namiki, M; Tsukamoto, T; Usami, M, 2010)
"We developed a combination chemotherapy, comprising weekly dosing of iv cisplatin (days 1 and 8) combined with a fixed dose (70 mg/m2/day) of S-1 (days 1-14) for patients with metastatic gastric cancer."2.72[S-1 combined with weekly dosing of cisplatin for metastatic gastric cancer]. ( Hyodo, I, 2006)
"Grade 4 neutropenia was observed in one of the 59 patients (1."2.72[Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer]. ( Kawahara, M; Yumine, K, 2006)
"The incidence and mortality of pancreatic cancer has increased very rapidly in Japan."2.72[Combination chemotherapy with gemcitabine and S-1 for advanced pancreatic cancer]. ( Ishihara, T; Nakamura, K; Saisho, H; Sudo, K; Yamaguchi, T, 2006)
" We assumed that the recommended dosage of TXT was 30 mg/m(2) and that of TS-1 was 60 mg/m(2) with radiotherapy of 60 Gy."2.72[A phase I/II study of docetaxel/TS-1 with radiation for esophageal cancer patients--step 1]. ( Higashida, M; Hirabayashi, Y; Hirai, T; Hiratsuka, J; Imajyo, Y; Kawabe, Y; Matsumoto, H; Murakami, H; Tsunoda, T; Urakami, A; Yamashita, K, 2006)
"Paclitaxel was scheduled to be given intravenously on days 1 and 8."2.43[S-1 combined with weekly paclitaxel in patients with advanced gastric cancer]. ( Gotoh, M; Kawabe, S; Takiuchi, H, 2006)
"Chemotherapy for colorectal cancer is now improving rapidly due to new drugs like oxaliplatin and molecular targeting drugs."2.43[S-1 as a single agent for colorectal cancer]. ( Eguchi, T; Shirao, K, 2006)
"Most cases of head and neck squamous cell carcinoma (HNSCC) are in the advanced stages, resulting in a poor prognosis."2.43[Adjuvant chemotherapy with S-1 for advanced head and neck carcinoma]. ( Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Toth, G; Tsukuda, M; Yoshida, T, 2006)
"The prognosis for locally advanced gastric cancer (AGC) remains unsatisfactory, even with S-1 adjuvant chemotherapy."1.43Efficacy of neoadjuvant chemotherapy with docetaxel, cisplatin and S-1 for resectable locally advanced gastric cancer. ( Aizawa, M; Matsuki, A; Migita, K; Nashimoto, A; Yabusaki, H, 2016)
"Nausea was improved in the next morning, and the patient ate almost all of his breakfast."1.38[Low-dose mirtazapine improved nausea and appetite loss during S-1 therapy]. ( Imai, E; Ito, T; Nishimura, D; Shibahara, H; Uematsu, N, 2012)
"Patients who had Japanese Gastric Cancer Association (JGCA) cStage IIIB gastric cancer were enrolled onto this study and received oral S-1 (65 mg/m(2)/day) administration and 50-Gy radiotherapy followed by radical surgery."1.38Pilot feasibility study of neoadjuvant chemoradiotherapy with S-1 in patients with locally advanced gastric cancer featuring adjacent tissue invasion or JGCA bulky N2 lymph node metastases. ( Hagiike, M; Inoue, T; Kimura, T; Okano, K; Suzuki, Y; Usuki, H; Yachida, S, 2012)
" The types and incidence rate of adverse events related to chemotherapy and the results of follow up of the patients were analyzed."1.38[A safety analysis in patients treated with oxaliplatin plus S-1 as adjuvant therapy for gastric cancer]. ( Chi, Y; Huang, J; Lü, X; Qu, T; Wang, JW; Yang, L; Zhou, Y, 2012)
"We report a rare patient with a DPD deficiency."1.33[A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency]. ( Arai, K; Hashimoto, T; Hiruma, K; Iwasaki, Y; Matsumoto, H; Saze, Z; Takahashi, K; Yamaguchi, T; Yamashita, Y; Yasutome, M, 2006)
" Thus, TS-1 and CPT-11 combination therapy has been effective for 17 months, suggesting that it is promising for long-term administration and survival to continue it perseveringly."1.33[A case of non-curatively resected gastric cancer successfully treated over 17 months with TS-1 and irinotecan combination therapy]. ( Kawamura, S; Okumura, S; Shimada, E; Sumi, Y; Tei, M; Yamagishi, D, 2006)
"We report two metastatic pancreatic cancer patients who showed marked tumor shrinkage following administration of the oral fluorinated pyrimidine anticancer drug, S-1."1.33[Two patients effectively treated by S-1 monotherapy for metastatic pancreatic cancer]. ( Ikeda, M; Ueno, H, 2006)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.08)18.2507
2000's28 (57.14)29.6817
2010's17 (34.69)24.3611
2020's2 (4.08)2.80

Authors

AuthorsStudies
Hirahara, N1
Matsubara, T1
Kaji, S1
Yamamoto, T2
Hyakudomi, R1
Takai, K1
Ishitobi, K1
Uchida, Y1
Tajima, Y1
Kobayashi, S2
Ueno, M1
Ogawa, G1
Fukutomi, A2
Ikeda, M3
Okusaka, T3
Sato, T2
Ito, Y1
Kadota, T1
Ioka, T1
Sugimori, K1
Sata, N1
Nakamori, S2
Shimizu, K1
Mizuno, N1
Ishii, H1
Furuse, J2
Li, J1
Xu, R1
Xu, J1
Denda, T2
Ikejiri, K1
Shen, L1
Toh, Y1
Shimada, K2
Kato, T2
Sakai, K1
Yamamoto, M1
Mishima, H1
Wang, J1
Baba, H2
Huang, D1
Ba, Y1
Xiong, J1
Xu, N1
Yan, Z1
Zhuang, Z1
Yu, Z2
Wan, H1
Zhang, Y1
Deng, T1
Zheng, R1
Guo, Z1
Hu, C1
Wang, M1
Yao, Y1
Meng, J1
Takeda, H1
Nishikawa, H1
Tsumura, T1
Sekikawa, A1
Maruo, T1
Okabe, Y1
Kimura, T2
Wakasa, T1
Osaki, Y1
Tsuburaya, A1
Yoshida, K2
Kobayashi, M2
Yoshino, S1
Takahashi, M1
Takiguchi, N1
Tanabe, K2
Takahashi, N1
Imamura, H2
Tatsumoto, N1
Hara, A1
Nishikawa, K1
Fukushima, R1
Nozaki, I1
Kojima, H1
Miyashita, Y1
Oba, K1
Buyse, M1
Morita, S3
Sakamoto, J2
Nakai, Y1
Isayama, H1
Saito, K1
Sasaki, T2
Takahara, N1
Hamada, T2
Mizuno, S1
Miyabayashi, K1
Yamamoto, K1
Mohri, D1
Kogure, H1
Yamamoto, N1
Hirano, K1
Ijichi, H1
Tateishi, K1
Tada, M1
Koike, K1
Migita, K1
Nashimoto, A1
Yabusaki, H1
Matsuki, A1
Aizawa, M1
Honda, G1
Kurata, M1
Okuda, Y1
Sakamoto, K1
Karasawa, K1
Chang, T1
Egawa, N1
Kamisawa, T1
Omuro, Y1
Tsuruta, K1
Koizumi, W1
Akiya, T1
Sato, A1
Sakuyama, T1
Sasaki, E1
Tomidokoro, T1
Fujimori, M1
Kikuchi, Y1
Mine, T1
Yamaguchi, K1
Kurihara, M1
Sudo, K2
Yamaguchi, T4
Ishihara, T2
Nakamura, K3
Hara, T1
Tawada, K1
Imagumbai, T1
Araki, H1
Sakai, M1
Hatano, K1
Kawakami, H1
Uno, T1
Ito, H1
Yokosuka, O2
Akaza, H1
Ikemoto, I1
Namiki, M1
Usami, M1
Fujimoto, H1
Tsukamoto, T1
Naito, S1
Tsushima, T1
Hironaka, S1
Boku, N2
Machida, N1
Yamazaki, K1
Yasui, H2
Taku, K1
Onozawa, Y1
Ueno, H3
Yamao, K1
Funakoshi, A1
Ohkawa, S1
Tanaka, K1
Moriyasu, F1
Shibahara, H1
Ito, T1
Uematsu, N1
Imai, E1
Nishimura, D1
Inoue, T1
Yachida, S1
Usuki, H1
Hagiike, M1
Okano, K1
Suzuki, Y1
Kunisaki, C1
Ono, HA1
Hasegawa, S1
Oshima, T1
Fujii, S1
Tokuhisa, M1
Izumisawa, Y1
Takagawa, R1
Kimura, J1
Kosaka, T1
Makino, H1
Akiyama, H1
Endo, I1
Zhou, Y1
Huang, J1
Yang, L1
Chi, Y1
Qu, T1
Lü, X1
Wang, JW1
Nakata, K1
Sakata, K1
Someya, M1
Miura, K1
Hayashi, J1
Hori, M1
Takagi, M1
Himi, T1
Kondo, A1
Hareyama, M1
Arai, K2
Iwasaki, Y2
Kimura, Y2
Takahashi, K2
Honma, S1
Takahashi, T1
Shima, Y1
Horimi, T1
Nishioka, Y1
Okabayashi, T1
Hamada, M1
Ishikawa, T1
Shibuya, Y1
Sakurama, K1
Nishie, M1
Iwata, J1
Tsuji, A1
Saeki, T1
Takashima, S1
Sano, M1
Horikoshi, N1
Miura, S1
Shimizu, S1
Morimoto, K1
Kimura, M2
Taguchi, T2
Johira, H1
Yunoki, S1
Kawata, N1
Watanabe, N1
Hachisuka, Y1
Uomoto, M1
Hatano, H1
Sanada, E1
Watanabe, R1
Ohmori, K1
Miyata, N1
Nakashima, T1
Kuratomi, Y1
Masuda, M1
Hirakawa, N1
Shioyama, Y1
Umezaki, T1
Komune, S1
Takahashi, I2
Emi, Y1
Kakeji, Y2
Tokunaga, E1
Ushiro, S1
Oki, E2
Watanabe, M1
Maehara, Y3
Goto, A2
Yamada, Y1
Kato, K1
Hamaguchi, T1
Muro, K1
Shimada, Y1
Shirao, K2
Hashimoto, T1
Saze, Z1
Matsumoto, H2
Yasutome, M1
Hiruma, K1
Yamashita, Y1
Ohtsu, A1
Hyodo, I1
Wada, Y1
Ukon, K1
Hihara, J1
Egashira, A1
Morita, M1
Gotoh, M1
Kawabe, S1
Takiuchi, H3
Eguchi, T1
Fujii, M1
Tsukuda, M2
Ishitoya, J1
Mikami, Y1
Matsuda, H1
Katori, H1
Horiuchi, C1
Yoshida, T1
Toth, G1
Yumine, K1
Kawahara, M1
Nakazawa, M1
Wataya, H1
Ichinose, Y1
Morizane, C1
Saisho, H1
Kawamura, S1
Yamagishi, D1
Tei, M1
Sumi, Y1
Shimada, E1
Okumura, S1
Hirai, T1
Hirabayashi, Y1
Murakami, H1
Higashida, M1
Kawabe, Y1
Urakami, A1
Yamashita, K1
Hiratsuka, J1
Imajyo, Y1
Tsunoda, T1
Lee, JL1
Kang, HJ1
Kang, YK1
Ryu, MH1
Chang, HM1
Kim, TW1
Sohn, HJ1
Kim, H1
Lee, JS1
Goto, M1
Furukawa, H1
Imano, M1
Imamoto, H1
Ishida, H1
Fujitani, K1
Narahara, H1
Shimokawa, T1
Nakajo, A1
Hokita, S1
Ishigami, S1
Miyazono, F1
Etoh, T1
Hamanoue, M1
Maenohara, S1
Iwashita, T1
Komatsu, H1
Satoh, K1
Aridome, K1
Natsugoe, S1
Nakano, S1
Aikou, T1
Shirasaka, T1
Shimamoto, Y1
Fukushima, M1
Inuyama, Y1
Kida, A1
Kohno, N1
Satake, B1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Paclitaxel Liposome Plus S-1 as Neoadjuvant Chemotherapy for Advanced Gastric Cancer[NCT02163291]Phase 230 participants (Anticipated)Interventional2013-12-31Not yet recruiting
A Prospective,Multicentral,Open-label,Randomized,Controlled,Phase III Clinical Trial to Compare S-1 for 6 Months to 1 Year as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer Staged II , IIIA or IIIB.[NCT02736552]Phase 30 participants (Actual)Interventional2016-03-31Withdrawn
Phase III Trial of S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for First Line Treatment of Advanced Gastric Cancer[NCT01671449]Phase 3338 participants (Actual)Interventional2012-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for oxonic acid and Anorexia

ArticleYear
[Combination chemotherapy of S-1 plus biweekly docetaxel for advanced and recurrent gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Animals; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic

2006
[S-1 combined with weekly paclitaxel in patients with advanced gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Clinical Tri

2006
[S-1 as a single agent for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2006
[The current evidence of S-1 and irinotecan hydrochloride combination chemotherapy with tri-weekly schedule].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials

2006
[Combination therapy with S-1 and CDDP for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Adult; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinom

2006
[Adjuvant chemotherapy with S-1 for advanced head and neck carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Anorexia; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Ad

2006
[Combination chemotherapy with S-1 and cisplatin for non-small cell lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, N

2006
[Invention of a tumor-selective 5-fluorouracil derivative named S-1 by biochemical modulation of 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Animals; Anorexia; Antimetabolites, Antineoplastic; Diarrhea; Dogs; Drug Combinations; Female; Fluor

1998

Trials

29 trials available for oxonic acid and Anorexia

ArticleYear
Phase II feasibility study of adjuvant chemotherapy with docetaxel/cisplatin/S-1 followed by S-1 for stage III gastric cancer.
    BMC cancer, 2021, Oct-01, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy

2021
Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer: Regimen of 1 week on, 1 week off.
    Cancer science, 2017, Volume: 108, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; China; Col

2017
A multicentre randomised trial comparing weekly paclitaxel + S-1 with weekly paclitaxel + 5-fluorouracil for patients with advanced gastric cancer.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:14

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protoc

2013
Sequential paclitaxel followed by tegafur and uracil (UFT) or S-1 versus UFT or S-1 monotherapy as adjuvant chemotherapy for T4a/b gastric cancer (SAMIT): a phase 3 factorial randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:8

    Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva

2014
A phase I trial of gemcitabine, S-1 and LV combination (GSL) therapy in advanced pancreatic cancer.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:5

    Topics: Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Diarrhea; Dose-Respon

2014
A Phase I Study of S-1 and Gemcitabine with Concurrent Radiotherapy in Patients with Non-Metastatic Advanced Pancreatic Cancer.
    Hepato-gastroenterology, 2015, Volume: 62, Issue:140

    Topics: Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Chemor

2015
Phase II study of S-1 as first-line treatment for elderly patients over 75 years of age with advanced gastric cancer: the Tokyo Cooperative Oncology Group study.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:6

    Topics: Aged; Aged, 80 and over; Anorexia; Antimetabolites, Antineoplastic; Drug Combinations; Fatigue; Fema

2010
Phase II study of oral S-1 and concurrent radiotherapy in patients with unresectable locally advanced pancreatic cancer.
    International journal of radiation oncology, biology, physics, 2011, May-01, Volume: 80, Issue:1

    Topics: Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; CA-19-9 Antigen; Combined Modality Therapy;

2011
Efficacy of S-1 in patients with castration-resistant prostate cancer: a phase II study.
    Oncology, 2010, Volume: 78, Issue:5-6

    Topics: Adult; Aged; Alanine Transaminase; Androgen Antagonists; Anorexia; Antimetabolites, Antineoplastic;

2010
Safety and efficacy of S-1 monotherapy in elderly patients with advanced gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2010, Volume: 13, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Anemia; Anorexia; Antime

2010
Multicenter phase II study of gemcitabine and S-1 combination therapy (GS Therapy) in patients with metastatic pancreatic cancer.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ad

2011
Low-dose docetaxel and cisplatin combination chemotherapy for stage II/III gastric cancer showing resistance to S-1 adjuvant chemotherapy: a phase I study.
    Journal of chemotherapy (Florence, Italy), 2012, Volume: 24, Issue:6

    Topics: Aged; Anorexia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy,

2012
Phase I study of oral S-1 and concurrent radiotherapy in patients with head and neck cancer.
    Journal of radiation research, 2013, Jul-01, Volume: 54, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anorexia; Antimetabolites, Antineoplastic; Carcinoma,

2013
[Efficacy and safety of novel oral fluoropyrimidine anticancer drug, TS-1 for advanced and recurrent gastric cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:9

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Bilirubin; Drug Admini

2003
[A late phase II clinical study of S-1 in patients with progressed, refractory breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:4

    Topics: Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Breast Neoplasms; Diarrhea; Drug Administrat

2004
[Phase I study of concurrent radiotherapy with TS-1 and vitamin A (TAR Therapy) for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:6

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dru

2005
Phase I study of S-1 and biweekly docetaxel combination chemotherapy for advanced and recurrent gastric cancer.
    Oncology reports, 2006, Volume: 15, Issue:4

    Topics: Adult; Aged; Alopecia; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Area Under

2006
Phase II study of combination therapy with S-1 and irinotecan in patients with advanced colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Anemia; Anorexia; Antimetabolites, Antineoplastic; Antineoplastic Agent

2006
[S-1 combined with weekly dosing of cisplatin for metastatic gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplat

2006
[Combination chemotherapy of S-1 and docetaxel on advanced and recurrent gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administratio

2006
[Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-C

2006
[Preoperative chemotherapy with S-1 and low-dose cisplatin for oral squamous cell carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy

2006
[S-1 monotherapy for pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Aged; Anorexia; Antimetabolites, Antineoplastic; Drug Administration Schedule;

2006
[Combination chemotherapy with gemcitabine and S-1 for advanced pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Pr

2006
[A phase I/II study of docetaxel/TS-1 with radiation for esophageal cancer patients--step 1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:13

    Topics: Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Docetaxel

2006
Phase I/II study of 3-week combination of S-1 and cisplatin chemotherapy for metastatic or recurrent gastric cancer.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5

    Topics: Adult; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diarrhea;

2008
Multi-center phase II study for combination therapy with paclitaxel/doxifluridine to treat advanced/recurrent gastric cancer showing resistance to S-1 (OGSG 0302).
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Disease-Free

2008
A multicenter phase II study of biweekly paclitaxel and S-1 combination chemotherapy for unresectable or recurrent gastric cancer.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:6

    Topics: Adenocarcinoma; Aged; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Disease Pr

2008
[Early phase II study of S-1 in patients with advanced head and neck cancer. S-1 Cooperative Study Group (Head and Neck Working Group)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:8

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Carcinoma, Squamous Ce

1998

Other Studies

12 other studies available for oxonic acid and Anorexia

ArticleYear
Impact of Renal Function on S-1 + Radiotherapy for Locally Advanced Pancreatic Cancer: An Integrated Analysis of Data From 2 Clinical Trials.
    Pancreas, 2021, 08-01, Volume: 50, Issue:7

    Topics: Aged; Anorexia; Antimetabolites, Antineoplastic; Chemoradiotherapy; Clinical Trials as Topic; Drug C

2021
Prominent hypereosinophilia with disseminated intravascular coagulation as an unusual presentation of advanced gastric cancer.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:6

    Topics: Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Bone Marrow Neo

2014
Efficacy of neoadjuvant chemotherapy with docetaxel, cisplatin and S-1 for resectable locally advanced gastric cancer.
    International journal of clinical oncology, 2016, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Ch

2016
[Low-dose mirtazapine improved nausea and appetite loss during S-1 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:1

    Topics: Aged, 80 and over; Anorexia; Antimetabolites, Antineoplastic; Drug Combinations; Histamine H1 Antago

2012
Pilot feasibility study of neoadjuvant chemoradiotherapy with S-1 in patients with locally advanced gastric cancer featuring adjacent tissue invasion or JGCA bulky N2 lymph node metastases.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anorexia; Antimetabolites, Antineoplastic; Chemoradiotherap

2012
[A safety analysis in patients treated with oxaliplatin plus S-1 as adjuvant therapy for gastric cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy,

2012
[Two resected cases of advanced gastric cancer with peritoneal dissemination after successful treatment with TS-1 plus low-dose CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:13

    Topics: Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationshi

2003
[Results of treatment of far advanced and recurrent stomach cancer with TS-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antimetabolites, Antineoplastic; Drug Administration Sched

2005
[A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Adult; Anorexia; Antimetabolites, Antineoplastic; Bone Neoplasms; Cerebral Hemorrhage; Dihydropyrimi

2006
[Japanese nationwide post-marketing survey of S-1 in patients with advanced gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Aged; Anorexia; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Dr

2006
[A case of non-curatively resected gastric cancer successfully treated over 17 months with TS-1 and irinotecan combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; D

2006
[Two patients effectively treated by S-1 monotherapy for metastatic pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Aged; Anorexia; Antimetabolites, Antineoplastic; Clinical Trials, Phase II as Topic;

2006