Page last updated: 2024-11-02

oxonic acid and Anasarca

oxonic acid has been researched along with Anasarca in 10 studies

Oxonic Acid: Antagonist of urate oxidase.

Research Excerpts

ExcerptRelevanceReference
" The RSGE treatment dose-dependently reduced PO- and MSU-induced paw edema, serum TNF-α, IL-1β, IL-6, IL-12, uric acid, and BUN, while significantly elevated serum IL-10, urinary uric acid and creatinine levels as compared with the respective values in the hyperuricemic and gouty mice group (vehicle group)."7.91Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice. ( Chang, Y; Liang, C; Liang, G; Nie, Y; Xiao, D; Zeng, S; Zhan, S; Zheng, Q; Zheng, X, 2019)
" The RSGE treatment dose-dependently reduced PO- and MSU-induced paw edema, serum TNF-α, IL-1β, IL-6, IL-12, uric acid, and BUN, while significantly elevated serum IL-10, urinary uric acid and creatinine levels as compared with the respective values in the hyperuricemic and gouty mice group (vehicle group)."3.91Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice. ( Chang, Y; Liang, C; Liang, G; Nie, Y; Xiao, D; Zeng, S; Zhan, S; Zheng, Q; Zheng, X, 2019)
" affine extract was evaluated in an experimental model with potassium oxonate (PO) induced hyperuricemia in mice which was used to evaluate anti-hyperuricemia activity and xanthine oxidase (XO) inhibition."3.85Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis. ( Cheng, L; Hu, YJ; Li, LN; Liang, WQ; Liu, PG; Pu, JB; Xu, P; Yang, QQ; Zhang, HJ; Zhang, YQ; Zhou, J, 2017)
"Pancreatic cancer is frequently complicated by malignancies in other organs."1.39Synchronous triple cancers of the pancreas, stomach, and cecum treated with S-1 followed by pancrelipase treatment of pancreatic exocrine insufficiency. ( Gabata, T; Ikeda, H; Ishikawa, D; Iwakami, S; Matsui, O; Mouri, H; Nanjo, S; Ohtsubo, K; Takamatsu, Y; Takeuchi, S; Yamada, T; Yamashita, K; Yano, S; Yasumoto, K, 2013)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, HJ1
Li, LN1
Zhou, J1
Yang, QQ1
Liu, PG1
Xu, P1
Liang, WQ1
Cheng, L1
Zhang, YQ1
Pu, JB1
Hu, YJ1
Liang, G1
Nie, Y1
Chang, Y1
Zeng, S1
Liang, C1
Zheng, X1
Xiao, D1
Zhan, S1
Zheng, Q1
Yang, TH1
Yan, DX1
Huang, XY1
Hou, B1
Ma, YB1
Peng, H1
Zhang, XM1
Chen, JJ1
Geng, CA1
Ohtsubo, K1
Ishikawa, D1
Nanjo, S1
Takeuchi, S1
Yamada, T1
Mouri, H1
Yamashita, K1
Yasumoto, K1
Gabata, T1
Matsui, O1
Ikeda, H1
Takamatsu, Y1
Iwakami, S1
Yano, S1
Takashima, T1
Mukai, H1
Hara, F1
Matsubara, N1
Saito, T1
Takano, T1
Park, Y1
Toyama, T1
Hozumi, Y1
Tsurutani, J1
Imoto, S1
Watanabe, T1
Sagara, Y1
Nishimura, R1
Shimozuma, K1
Ohashi, Y1
Silva, CR1
Fröhlich, JK1
Oliveira, SM1
Cabreira, TN1
Rossato, MF1
Trevisan, G1
Froeder, AL1
Bochi, GV1
Moresco, RN1
Athayde, ML1
Ferreira, J1
Makari, Y1
Fujiwara, Y1
Yasuda, T1
Takiguchi, S1
Kimura, Y1
Yano, M1
Monden, M1
Liu, L1
Inoue, H1
Nakayama, H1
Kanno, R1
Kanno, M1
Chang, YH1
Bluestone, R1
Hayashi, T1
Hasegawa, H1
Tanaka, G1
Ohmae, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Cisplatin Combined With Oral TS-1 in Patients With Advanced Solid Tumors With Different Degrees of Liver Dysfunction[NCT03519074]Phase 248 participants (Anticipated)Interventional2016-07-22Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for oxonic acid and Anasarca

ArticleYear
Taxanes versus S-1 as the first-line chemotherapy for metastatic breast cancer (SELECT BC): an open-label, non-inferiority, randomised phase 3 trial.
    The Lancet. Oncology, 2016, Volume: 17, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Disease

2016

Other Studies

9 other studies available for oxonic acid and Anasarca

ArticleYear
Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis.
    Journal of ethnopharmacology, 2017, May-05, Volume: 203

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Chromatography, High Pressure Liquid; Disease M

2017
Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 59

    Topics: Animals; Antioxidants; Arthritis, Gouty; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Flavo

2019
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis.
    Phytochemistry, 2019, Volume: 164

    Topics: Anacardiaceae; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Chalcone; Dose-Re

2019
Synchronous triple cancers of the pancreas, stomach, and cecum treated with S-1 followed by pancrelipase treatment of pancreatic exocrine insufficiency.
    JOP : Journal of the pancreas, 2013, Sep-10, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Cecal Neoplasms; Drug Combinations; Edema; Humans; Hypo

2013
The antinociceptive and anti-inflammatory effects of the crude extract of Jatropha isabellei in a rat gout model.
    Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Biomarkers, Pharmacological; Disease

2013
[Weekly administration of paclitaxel as a second-line chemotherapy for advanced and recurrent gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:4

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Drug Administration Schedu

2004
The endogenous danger signal uric Acid augments contact hypersensitivity responses in mice.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 2007, Volume: 74, Issue:3

    Topics: Animals; B7-2 Antigen; CD40 Antigens; Chlorobenzenes; Dendritic Cells; Dermatitis, Contact; Drug Syn

2007
Adjuvant polyarthritis. VI. Effect of oxonate-induced hyperuricemia on the development of acute inflammation, immune response and adjuvant arthritis.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3

    Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Cell Line; Diet; Edema; Immunity, C

1981
[A 13-week oral repeated dose toxicity study of a new antineoplastic agent S-1 in rats].
    The Journal of toxicological sciences, 1996, Volume: 21 Suppl 3

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy

1996