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oxiracetam and Dementia

oxiracetam has been researched along with Dementia in 7 studies

oxiracetam: structure in first source

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of Oxiracetam (1600 mg/day) versus placebo was assessed in a group of 96 out-patients suffering from cognitive disorders secondary to primary degenerative dementia."9.07Treatment of cognitive impairment secondary to degenerative dementia. Effectiveness of oxiracetam therapy. ( Bianchetti, A; Rozzini, R; Zanetti, O, 1993)
"The effectiveness of oxiracetam (1600 mg/day) vs placebo was assessed in a group of 96 out-patients suffering from cognitive disorders secondary to primary degenerative dementia."9.07Effectiveness of oxiracetam therapy in the treatment of cognitive deficiencies secondary to primary degenerative dementia. ( Bianchetti, A; Rozzini, R; Zanetti, O, 1992)
"Oxiracetam is a recently synthesized nootropic that was tested as a potential treatment for cognitive decline in patients with multi-infarct dementia (MID) and primary degenerative dementia (PDD)."9.06Oxiracetam in the treatment of multi-infarct dementia and primary degenerative dementia. ( Dysken, MW; Katz, R; Kuskowski, M; Stallone, F, 1989)
"A multicentre, double-blind, between-patient study was carried out to evaluate the efficacy and tolerability of oxiracetam (800-mg tablets), in comparison with placebo, each given twice daily for 12 weeks to patients suffering from primary degenerative, multi-infarct or mixed forms of dementia."9.06Oxiracetam in the treatment of primary degenerative and multi-infarct dementia: a double-blind, placebo-controlled study. ( Bonavita, E; Fagiani, MB; Ferrario, E; Fiori, L; Ghiazza, B; Maina, G; Ravizza, L; Teruzzi, F; Torta, R; Zagnoni, PG, 1989)
"40 out-patients with a mild to moderate degree of dementia (11 less than or equal to MMSE less than 24) participated in a between-subjects (n = 20 + 20) double-blind placebo-controlled randomized trial comparing the effects of oxiracetam 800 mg bid and placebo during 90 days of treatment."9.06Clinical and neuropsychological study with oxiracetam versus placebo in patients with mild to moderate dementia. ( Grioli, S; Lomeo, C; Parini, J; Quattropani, M; Scapagnini, U; Villardita, C, 1987)
"The effectiveness of Oxiracetam (1600 mg/day) versus placebo was assessed in a group of 96 out-patients suffering from cognitive disorders secondary to primary degenerative dementia."5.07Treatment of cognitive impairment secondary to degenerative dementia. Effectiveness of oxiracetam therapy. ( Bianchetti, A; Rozzini, R; Zanetti, O, 1993)
"The effectiveness of oxiracetam (1600 mg/day) vs placebo was assessed in a group of 96 out-patients suffering from cognitive disorders secondary to primary degenerative dementia."5.07Effectiveness of oxiracetam therapy in the treatment of cognitive deficiencies secondary to primary degenerative dementia. ( Bianchetti, A; Rozzini, R; Zanetti, O, 1992)
"Oxiracetam is a recently synthesized nootropic that was tested as a potential treatment for cognitive decline in patients with multi-infarct dementia (MID) and primary degenerative dementia (PDD)."5.06Oxiracetam in the treatment of multi-infarct dementia and primary degenerative dementia. ( Dysken, MW; Katz, R; Kuskowski, M; Stallone, F, 1989)
"A multicentre, double-blind, between-patient study was carried out to evaluate the efficacy and tolerability of oxiracetam (800-mg tablets), in comparison with placebo, each given twice daily for 12 weeks to patients suffering from primary degenerative, multi-infarct or mixed forms of dementia."5.06Oxiracetam in the treatment of primary degenerative and multi-infarct dementia: a double-blind, placebo-controlled study. ( Bonavita, E; Fagiani, MB; Ferrario, E; Fiori, L; Ghiazza, B; Maina, G; Ravizza, L; Teruzzi, F; Torta, R; Zagnoni, PG, 1989)
"40 out-patients with a mild to moderate degree of dementia (11 less than or equal to MMSE less than 24) participated in a between-subjects (n = 20 + 20) double-blind placebo-controlled randomized trial comparing the effects of oxiracetam 800 mg bid and placebo during 90 days of treatment."5.06Clinical and neuropsychological study with oxiracetam versus placebo in patients with mild to moderate dementia. ( Grioli, S; Lomeo, C; Parini, J; Quattropani, M; Scapagnini, U; Villardita, C, 1987)
"Oxiracetam, a new substance found to be a nootropic in experimental pharmacological studies, was tested in three clinical trials: a single rising dose tolerance and dose-finding study with quantitative pharmaco-electroencephalogram (pharmaco-EEG) and quantitative pharmacopsychology in healthy volunteers; a dose-finding study, at three dose levels for 3 months, with quantitative pharmaco-EEG in mild to moderate dementia patients; and a safety and efficacy study with increasing dosages for 12 weeks with subjective and objective tests in elderly patients with dementia."3.67CNS pharmacology and clinical therapeutic effects of oxiracetam. ( Itil, KZ; Itil, TM; Menon, GN; Songar, A, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rozzini, R2
Zanetti, O2
Bianchetti, A2
Dysken, MW1
Katz, R1
Stallone, F1
Kuskowski, M1
Gava, R1
Schifano, F1
Maina, G1
Fiori, L1
Torta, R1
Fagiani, MB1
Ravizza, L1
Bonavita, E1
Ghiazza, B1
Teruzzi, F1
Zagnoni, PG1
Ferrario, E1
Villardita, C1
Parini, J1
Grioli, S1
Quattropani, M1
Lomeo, C1
Scapagnini, U1
Itil, TM1
Menon, GN1
Songar, A1
Itil, KZ1

Reviews

1 review available for oxiracetam and Dementia

ArticleYear
[Oxiracetam].
    Giornale di clinica medica, 1989, Volume: 70, Issue:1

    Topics: Adult; Aged; Animals; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia; Dogs; Humans; M

1989

Trials

6 trials available for oxiracetam and Dementia

ArticleYear
Treatment of cognitive impairment secondary to degenerative dementia. Effectiveness of oxiracetam therapy.
    Acta neurologica, 1993, Volume: 15, Issue:1

    Topics: Aged; Ambulatory Care; Cognition Disorders; Dementia; Double-Blind Method; Female; Humans; Male; Neu

1993
Effectiveness of oxiracetam therapy in the treatment of cognitive deficiencies secondary to primary degenerative dementia.
    Acta neurologica, 1992, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Dementia; Double-Blind Method; Female; Humans; Male; N

1992
Oxiracetam in the treatment of multi-infarct dementia and primary degenerative dementia.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Summer, Volume: 1, Issue:3

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Dementia; Dementia, Multi-Infarct; Dose-Respons

1989
[Oxiracetam].
    Giornale di clinica medica, 1989, Volume: 70, Issue:1

    Topics: Adult; Aged; Animals; Cerebrovascular Disorders; Clinical Trials as Topic; Dementia; Dogs; Humans; M

1989
Oxiracetam in the treatment of primary degenerative and multi-infarct dementia: a double-blind, placebo-controlled study.
    Neuropsychobiology, 1989, Volume: 21, Issue:3

    Topics: Aged; Aged, 80 and over; Dementia; Dementia, Multi-Infarct; Double-Blind Method; Female; Humans; Mal

1989
Clinical and neuropsychological study with oxiracetam versus placebo in patients with mild to moderate dementia.
    Journal of neural transmission. Supplementum, 1987, Volume: 24

    Topics: Aged; Cognition; Dementia; Double-Blind Method; Female; Humans; Male; Middle Aged; Pyrrolidines

1987

Other Studies

1 other study available for oxiracetam and Dementia

ArticleYear
CNS pharmacology and clinical therapeutic effects of oxiracetam.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 3

    Topics: Brain; Dementia; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Electroencephal

1986