oxiracetam has been researched along with Amnesia in 7 studies
oxiracetam: structure in first source
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The scopolamine model of amnesia has been used to test the pharmacodynamic efficacy of oxiracetam in 12 healthy volunteers." | 9.07 | Effects of acute doses of oxiracetam in the scopolamine model of human amnesia. ( Alberoni, M; Bressi, S; Canal, N; Cattaneo, C; Franceschi, M; Parini, J; Preda, L, 1993) |
| "Oxiracetam was injected immediately after the acquisition session(s), MK-801 was given 30 min before the retention session which followed 24 h after the acquisition session(s)." | 5.31 | Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice. ( Hlinák, Z; Krejcí, I, 2000) |
| "The scopolamine model of amnesia has been used to test the pharmacodynamic efficacy of oxiracetam in 12 healthy volunteers." | 5.07 | Effects of acute doses of oxiracetam in the scopolamine model of human amnesia. ( Alberoni, M; Bressi, S; Canal, N; Cattaneo, C; Franceschi, M; Parini, J; Preda, L, 1993) |
| "Oxiracetam was injected immediately after the acquisition session(s), MK-801 was given 30 min before the retention session which followed 24 h after the acquisition session(s)." | 1.31 | Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice. ( Hlinák, Z; Krejcí, I, 2000) |
| "3 and 1 mg/kg ip for most compounds), the presence of a bell-shaped dose-response curve and, generally, a reduction of biological activity after po administration." | 1.29 | Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers. ( Banfi, S; Biagetti, R; Cerri, A; Dorigotti, L; Farina, C; Magnani, M; Pfeiffer, U; Pinza, M; Pozzi, O; Riccaboni, MT, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pinza, M | 1 |
| Farina, C | 1 |
| Cerri, A | 1 |
| Pfeiffer, U | 1 |
| Riccaboni, MT | 1 |
| Banfi, S | 1 |
| Biagetti, R | 2 |
| Pozzi, O | 2 |
| Magnani, M | 2 |
| Dorigotti, L | 1 |
| Angelucci, L | 1 |
| Calvisi, P | 1 |
| Catini, R | 1 |
| Cosentino, U | 1 |
| Cozzolino, R | 1 |
| De Witt, P | 1 |
| Ghirardi, O | 1 |
| Giannessi, F | 1 |
| Giuliani, A | 1 |
| Guaraldi, D | 1 |
| Preda, L | 1 |
| Alberoni, M | 1 |
| Bressi, S | 1 |
| Cattaneo, C | 1 |
| Parini, J | 1 |
| Canal, N | 1 |
| Franceschi, M | 1 |
| Hlinák, Z | 1 |
| Krejcí, I | 1 |
| Belfiore, P | 1 |
| Ponzio, F | 1 |
| Berettera, C | 1 |
| Abe, E | 1 |
| Spignoli, G | 1 |
| Pepeu, G | 1 |
1 trial available for oxiracetam and Amnesia
| Article | Year |
|---|---|
Effects of acute doses of oxiracetam in the scopolamine model of human amnesia.
Topics: Adult; Amnesia; Attention; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method | 1993 |
6 other studies available for oxiracetam and Amnesia
| Article | Year |
|---|---|
Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers.
Topics: Amnesia; Animals; Avoidance Learning; Cognition; Imidazoles; Male; Mice; Molecular Structure; Pirace | 1993 |
Synthesis and amnesia-reversal activity of a series of 7- and 5-membered 3-acylamino lactams.
Topics: Amnesia; Animals; Brain; Cholinesterase Inhibitors; Drug Design; Electroshock; In Vitro Techniques; | 1993 |
Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice.
Topics: Amnesia; Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fema | 2000 |
Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker AP7.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Amnesia; Animals; Avoidance Learning; Corpu | 1992 |
Reversal effect of DM-9384 on scopolamine-induced acetylcholine depletion in certain regions of the mouse brain.
Topics: Acetylcholine; Amnesia; Animals; Brain Chemistry; Central Nervous System Agents; Male; Mice; Mice, I | 1991 |
Oxiracetam prevents electroshock-induced decrease in brain acetylcholine and amnesia.
Topics: Acetylcholine; Amnesia; Animals; Avoidance Learning; Brain; Cerebral Cortex; Choline; Electroshock; | 1986 |