Page last updated: 2024-11-02

oxiracetam and Amnesia

oxiracetam has been researched along with Amnesia in 7 studies

oxiracetam: structure in first source

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
"The scopolamine model of amnesia has been used to test the pharmacodynamic efficacy of oxiracetam in 12 healthy volunteers."9.07Effects of acute doses of oxiracetam in the scopolamine model of human amnesia. ( Alberoni, M; Bressi, S; Canal, N; Cattaneo, C; Franceschi, M; Parini, J; Preda, L, 1993)
"Oxiracetam was injected immediately after the acquisition session(s), MK-801 was given 30 min before the retention session which followed 24 h after the acquisition session(s)."5.31Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice. ( Hlinák, Z; Krejcí, I, 2000)
"The scopolamine model of amnesia has been used to test the pharmacodynamic efficacy of oxiracetam in 12 healthy volunteers."5.07Effects of acute doses of oxiracetam in the scopolamine model of human amnesia. ( Alberoni, M; Bressi, S; Canal, N; Cattaneo, C; Franceschi, M; Parini, J; Preda, L, 1993)
"Oxiracetam was injected immediately after the acquisition session(s), MK-801 was given 30 min before the retention session which followed 24 h after the acquisition session(s)."1.31Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice. ( Hlinák, Z; Krejcí, I, 2000)
"3 and 1 mg/kg ip for most compounds), the presence of a bell-shaped dose-response curve and, generally, a reduction of biological activity after po administration."1.29Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers. ( Banfi, S; Biagetti, R; Cerri, A; Dorigotti, L; Farina, C; Magnani, M; Pfeiffer, U; Pinza, M; Pozzi, O; Riccaboni, MT, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pinza, M1
Farina, C1
Cerri, A1
Pfeiffer, U1
Riccaboni, MT1
Banfi, S1
Biagetti, R2
Pozzi, O2
Magnani, M2
Dorigotti, L1
Angelucci, L1
Calvisi, P1
Catini, R1
Cosentino, U1
Cozzolino, R1
De Witt, P1
Ghirardi, O1
Giannessi, F1
Giuliani, A1
Guaraldi, D1
Preda, L1
Alberoni, M1
Bressi, S1
Cattaneo, C1
Parini, J1
Canal, N1
Franceschi, M1
Hlinák, Z1
Krejcí, I1
Belfiore, P1
Ponzio, F1
Berettera, C1
Abe, E1
Spignoli, G1
Pepeu, G1

Trials

1 trial available for oxiracetam and Amnesia

ArticleYear
Effects of acute doses of oxiracetam in the scopolamine model of human amnesia.
    Psychopharmacology, 1993, Volume: 110, Issue:4

    Topics: Adult; Amnesia; Attention; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method

1993

Other Studies

6 other studies available for oxiracetam and Amnesia

ArticleYear
Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers.
    Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26

    Topics: Amnesia; Animals; Avoidance Learning; Cognition; Imidazoles; Male; Mice; Molecular Structure; Pirace

1993
Synthesis and amnesia-reversal activity of a series of 7- and 5-membered 3-acylamino lactams.
    Journal of medicinal chemistry, 1993, May-28, Volume: 36, Issue:11

    Topics: Amnesia; Animals; Brain; Cholinesterase Inhibitors; Drug Design; Electroshock; In Vitro Techniques;

1993
Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice.
    Behavioural brain research, 2000, Dec-20, Volume: 117, Issue:1-2

    Topics: Amnesia; Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fema

2000
Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker AP7.
    Neuroscience letters, 1992, Aug-31, Volume: 143, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Amnesia; Animals; Avoidance Learning; Corpu

1992
Reversal effect of DM-9384 on scopolamine-induced acetylcholine depletion in certain regions of the mouse brain.
    Psychopharmacology, 1991, Volume: 105, Issue:3

    Topics: Acetylcholine; Amnesia; Animals; Brain Chemistry; Central Nervous System Agents; Male; Mice; Mice, I

1991
Oxiracetam prevents electroshock-induced decrease in brain acetylcholine and amnesia.
    European journal of pharmacology, 1986, Jul-31, Volume: 126, Issue:3

    Topics: Acetylcholine; Amnesia; Animals; Avoidance Learning; Brain; Cerebral Cortex; Choline; Electroshock;

1986