oxilorphan and Heroin-Dependence

oxilorphan has been researched along with Heroin-Dependence* in 1 studies

Other Studies

1 other study(ies) available for oxilorphan and Heroin-Dependence

ArticleYear
Clinical trial in post-addicts with oxilorphan (levo-BC-2605): a new narcotic antagonist.
    Drug and alcohol dependence, 1976, Volume: 1, Issue:5

    Oxilorphan (levo-BC-2605) is a new, long-acting, narcotic antagonist that has agonist properties. Twenty-one (21) heroin addicts in Los Angeles were detoxified and given at least one oral dose of oxilorphan. Only three (14.3%) patients took daily doses for 14 days, which was the maximal time allowed for oxilorphan administration in this study. The remainder discontinued oxilorphan because of subjective side effects or for unknown reasons. Side effects most responsible for dropouts were dysphoria, insomnia, weakness, hallucinations, nausea, drowsiness and anorexia. Oxilorphan provided 24-hour protection with a single, oral dose, but subjective side effects encountered during inductiolinical trials with oxilorphan should be attempted with other addict populations to fully determine its potential therapeutic value.

    Topics: Adult; Drug Evaluation; Female; Heroin Dependence; Humans; Male; Morphinans; Narcotic Antagonists; Substance Withdrawal Syndrome

1976