oxidopamine has been researched along with Striatonigral Atrophy in 10 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present experiment we studied the ability of embryonic striatal grafts to protect against striatal quinolinic acid (QA)-induced excitotoxicity in a previously established double lesion rat model of striatonigral degeneration (SND), the neuropathological substrate of parkinsonism associated with multiple system atrophy (MSA)." | 3.70 | Failure of neuroprotection by embryonic striatal grafts in a double lesion rat model of striatonigral degeneration (multiple system atrophy). ( Humpel, C; Levivier, M; Poewe, W; Puschban, Z; Scherfler, C; Seppi, K; Stefanova, N; Waldner, R; Wenning, GK, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (80.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quintino, L | 1 |
| Avallone, M | 1 |
| Brännstrom, E | 1 |
| Kavanagh, P | 1 |
| Lockowandt, M | 1 |
| Garcia Jareño, P | 1 |
| Breger, LS | 1 |
| Lundberg, C | 1 |
| Yoon, HH | 1 |
| Kim, YH | 1 |
| Shin, ES | 1 |
| Jeon, SR | 1 |
| Kostrzewa, RM | 1 |
| Kostrzewa, JP | 1 |
| Brown, RW | 1 |
| Nowak, P | 1 |
| Brus, R | 1 |
| Rodríguez, M | 1 |
| González, J | 1 |
| Sabaté, M | 1 |
| Obeso, J | 1 |
| Pereda, E | 1 |
| Gomide, VC | 1 |
| Silveira, GA | 1 |
| Chadi, G | 1 |
| Puschban, Z | 2 |
| Waldner, R | 1 |
| Seppi, K | 1 |
| Stefanova, N | 1 |
| Humpel, C | 1 |
| Scherfler, C | 2 |
| Levivier, M | 1 |
| Poewe, W | 2 |
| Wenning, GK | 2 |
| Ghorayeb, I | 1 |
| Goebel, GP | 1 |
| Tison, F | 1 |
| Jellinger, K | 1 |
| Tarazi, FI | 1 |
| Zhang, K | 1 |
| Baldessarini, RJ | 1 |
| Shults, CW | 1 |
| Ray, J | 1 |
| Tsuboi, K | 1 |
| Gage, FH | 1 |
| Roedter, A | 1 |
| Winkler, C | 1 |
| Samii, M | 1 |
| Walter, GF | 1 |
| Brandis, A | 1 |
| Nikkhah, G | 1 |
1 review available for oxidopamine and Striatonigral Atrophy
| Article | Year |
|---|---|
Dopamine receptor supersensitivity: development, mechanisms, presentation, and clinical applicability.
Topics: 5,7-Dihydroxytryptamine; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Denervation; Oxid | 2008 |
9 other studies available for oxidopamine and Striatonigral Atrophy
| Article | Year |
|---|---|
GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration.
Topics: Animals; Female; Genetic Therapy; Glial Cell Line-Derived Neurotrophic Factor; Lentivirus; Oxidopami | 2019 |
A rat model of striatonigral degeneration generated by simultaneous injection of 6-hydroxydopamine into the medial forebrain bundle and quinolinic acid into the striatum.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Mem | 2014 |
Firing regulation in dopaminergic cells: effect of the partial degeneration of nigrostriatal system in surviving neurons.
Topics: Algorithms; Animals; Cell Survival; Dopamine; Electrophysiology; gamma-Aminobutyric Acid; Male; Mark | 2003 |
Transient and widespread astroglial activation in the brain after a striatal 6-OHDA-induced partial lesion of the nigrostriatal system.
Topics: Animals; Astrocytes; Cell Count; Functional Laterality; Glial Fibrillary Acidic Protein; Immunohisto | 2005 |
Failure of neuroprotection by embryonic striatal grafts in a double lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Animals; Apomorphine; Autoradiography; Binding, Competitive; Brain Tissue Transplantation; Corpus St | 2000 |
Complex motor disturbances in a sequential double lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Animals; Corpus Striatum; Disease Models, Animal; Glial Fibrillary Acidic Protein; Male; Motor Activ | 2000 |
Effects of nigrostriatal dopamine denervation on ionotropic glutamate receptors in rat caudate-putamen.
Topics: Adrenergic Agents; Animals; Caudate Nucleus; Denervation; Oxidopamine; Parkinsonian Disorders; Putam | 2000 |
Fibroblast growth factor-2-producing fibroblasts protect the nigrostriatal dopaminergic system from 6-hydroxydopamine.
Topics: Adrenergic Agents; Animals; beta-Galactosidase; Corpus Striatum; Female; Fibroblast Growth Factor 2; | 2000 |
Comparison of unilateral and bilateral intrastriatal 6-hydroxydopamine-induced axon terminal lesions: evidence for interhemispheric functional coupling of the two nigrostriatal pathways.
Topics: Adrenergic Agents; Animals; Caudate Nucleus; Corpus Striatum; Female; Motor Activity; Motor Skills; | 2001 |