oxidopamine has been researched along with Schizophrenia in 10 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we sought to verify the cytoprotective role of MGF on cultured rat primary mesencephalic cells exposed to 6-hydroxydopamine (6-OHDA) in vitro, and the MGFs anti-inflammatory potential in mouse model of ketamine-induced schizophrenia in vivo." | 7.78 | Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia. ( Andrade, GM; Carvalho, AC; Magalhães, HI; Moraes, MO; Morais, TC; Nobre-Júnior, HV; Rao, VS; Santos, FA; Trevisan, MT, 2012) |
| " Here we sought to verify the cytoprotective role of MGF on cultured rat primary mesencephalic cells exposed to 6-hydroxydopamine (6-OHDA) in vitro, and the MGFs anti-inflammatory potential in mouse model of ketamine-induced schizophrenia in vivo." | 3.78 | Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia. ( Andrade, GM; Carvalho, AC; Magalhães, HI; Moraes, MO; Morais, TC; Nobre-Júnior, HV; Rao, VS; Santos, FA; Trevisan, MT, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scornaiencki, R | 1 |
| Cantrup, R | 1 |
| Rushlow, WJ | 1 |
| Rajakumar, N | 1 |
| Rao, VS | 1 |
| Carvalho, AC | 1 |
| Trevisan, MT | 1 |
| Andrade, GM | 1 |
| Nobre-Júnior, HV | 1 |
| Moraes, MO | 1 |
| Magalhães, HI | 1 |
| Morais, TC | 1 |
| Santos, FA | 1 |
| Suzuki, M | 1 |
| Kawasaki, Y | 1 |
| Murata, M | 1 |
| Shibata, R | 1 |
| Kurachi, M | 1 |
| Mori, H | 1 |
| Fitzgerald, LW | 1 |
| Deutch, AY | 1 |
| Gasic, G | 1 |
| Heinemann, SF | 1 |
| Nestler, EJ | 1 |
| King, D | 1 |
| Zigmond, MJ | 1 |
| Finlay, JM | 1 |
| Rodríguez-Puertas, R | 1 |
| Herrera-Marschitz, M | 1 |
| Koistinaho, J | 1 |
| Hökfelt, T | 1 |
| Schwarzkopf, SB | 1 |
| Mitra, T | 1 |
| Bruno, JP | 1 |
| Swerdlow, NR | 2 |
| Braff, DL | 2 |
| Masten, VL | 1 |
| Geyer, MA | 2 |
| Koob, GF | 1 |
| Poliakov, IuF | 1 |
| Kurek, NS | 1 |
1 review available for oxidopamine and Schizophrenia
| Article | Year |
|---|---|
[Disorders of positive emotions in schizophrenics: survey of research, (problems, hypotheses)].
Topics: Animals; Brain Chemistry; Child; Child, Preschool; Cognition; Disease Models, Animal; Emotions; Fema | 1985 |
9 other studies available for oxidopamine and Schizophrenia
| Article | Year |
|---|---|
Prefrontal cortical D1 dopamine receptors modulate subcortical D2 dopamine receptor-mediated stress responsiveness.
Topics: Animals; Behavior, Animal; Benzazepines; Desipramine; Dopamine; Dopamine Agonists; Dopamine Antagoni | 2009 |
Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Behavior, Animal; Brain; Cell Death; Cel | 2012 |
Effects of 6-hydroxydopamine lesions of the medial prefrontal cortex on local cerebral blood flow and D1 and D2 dopamine receptor binding in rats: a quantitative autoradiographic study.
Topics: Animals; Autoradiography; Cerebrovascular Circulation; Frontal Lobe; Male; Oxidopamine; Rats; Rats, | 1995 |
Regulation of cortical and subcortical glutamate receptor subunit expression by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Benzazepines; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine; | 1995 |
Effects of dopamine depletion in the medial prefrontal cortex on the stress-induced increase in extracellular dopamine in the nucleus accumbens core and shell.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Age | 1997 |
Dopamine D1 receptor modulation of glutamate receptor messenger RNA levels in the neocortex and neostriatum of unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine; Dopa | 1999 |
Sensory gating in rats depleted of dopamine as neonates: potential relevance to findings in schizophrenic patients.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Brain; Chromatography, Liquid; Corpus Striatum; Dop | 1992 |
Schizophrenic-like sensorimotor gating abnormalities in rats following dopamine infusion into the nucleus accumbens.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Injections; Limbic System; Ma | 1990 |
Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics.
Topics: Acoustic Stimulation; Animals; Brain Chemistry; Disease Models, Animal; Hydroxydopamines; Male; Oxid | 1986 |