oxidopamine has been researched along with Retinal Degeneration in 3 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Studies on Parkinson's disease patients and dopamine-depleted animals indicate that dopaminergic neurons in the retina degenerate due to the genetic and environmental factors that cause dopaminergic neuron loss in the substantia nigra." | 1.37 | Minor retinal degeneration in Parkinson's disease. ( Huang, YM; Yin, ZQ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Li, P | 1 |
| Carr, AL | 1 |
| Gorsuch, R | 1 |
| Yarka, C | 1 |
| Li, J | 1 |
| Bartlett, M | 1 |
| Pfister, D | 1 |
| Hyde, DR | 1 |
| Li, L | 2 |
| Huang, YM | 1 |
| Yin, ZQ | 1 |
| Dowling, JE | 1 |
3 other studies available for oxidopamine and Retinal Degeneration
| Article | Year |
|---|---|
Transcription of the SCL/TAL1 interrupting Locus (Stil) is required for cell proliferation in adult Zebrafish Retinas.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Ependymoglial Cells; Gene | 2014 |
Minor retinal degeneration in Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Hallucinations; Haplorhini; Humans; | 2011 |
Effects of dopamine depletion on visual sensitivity of zebrafish.
Topics: Animals; Circadian Rhythm; Color Perception; Dark Adaptation; Dopamine; Dopamine Agonists; Electrore | 2000 |