oxidopamine has been researched along with Necrosis in 9 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The cytoprotective effect of central TRH on CCl(4)-induced acute hepatocellular necrosis was abolished by hepatic branch vagotomy, atropine, indomethacin and N(G)-nitro-L-arginine methyl ester, but not by 6-hydroxydopamine." | 7.72 | Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats. ( Makino, I; Nakamura, K; Sato, Y; Terano, A; Yoneda, M, 2003) |
| " The cytoprotective effect of central TRH on CCl(4)-induced acute hepatocellular necrosis was abolished by hepatic branch vagotomy, atropine, indomethacin and N(G)-nitro-L-arginine methyl ester, but not by 6-hydroxydopamine." | 3.72 | Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats. ( Makino, I; Nakamura, K; Sato, Y; Terano, A; Yoneda, M, 2003) |
| "Most of the Parkinson's disease (PD) cases are sporadic, although several genes are directly related to PD." | 1.51 | Necrosis, apoptosis, necroptosis, three modes of action of dopaminergic neuron neurotoxins. ( Callizot, N; Combes, M; Henriques, A; Poindron, P, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Callizot, N | 1 |
| Combes, M | 1 |
| Henriques, A | 1 |
| Poindron, P | 1 |
| Zerris, VA | 1 |
| Zheng, Z | 1 |
| Noren, G | 1 |
| Sungarian, A | 1 |
| Friehs, GM | 1 |
| Sato, Y | 1 |
| Yoneda, M | 1 |
| Nakamura, K | 1 |
| Makino, I | 1 |
| Terano, A | 1 |
| Oben, JA | 1 |
| Roskams, T | 1 |
| Yang, S | 1 |
| Lin, H | 1 |
| Sinelli, N | 1 |
| Li, Z | 1 |
| Torbenson, M | 1 |
| Huang, J | 1 |
| Guarino, P | 1 |
| Kafrouni, M | 1 |
| Diehl, AM | 1 |
| Kavanagh, ET | 1 |
| Loughlin, JP | 1 |
| Herbert, KR | 1 |
| Dockery, P | 1 |
| Samali, A | 1 |
| Doyle, KM | 1 |
| Gorman, AM | 1 |
| Tóth, ML | 1 |
| Simon, P | 1 |
| Kovács, AL | 1 |
| Vellai, T | 1 |
| Karagüzel, G | 1 |
| Gedikoğlu, G | 1 |
| Tanyel, FC | 1 |
| Büyükpamukçu, N | 1 |
| Hiçsönmez, A | 1 |
| Ochu, EE | 1 |
| Rothwell, NJ | 1 |
| Waters, CM | 1 |
| Woodgate, A | 1 |
| MacGibbon, G | 1 |
| Walton, M | 1 |
| Dragunow, M | 1 |
9 other studies available for oxidopamine and Necrosis
| Article | Year |
|---|---|
Necrosis, apoptosis, necroptosis, three modes of action of dopaminergic neuron neurotoxins.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neur | 2019 |
Radiation and regeneration: behavioral improvement and GDNF expression after Gamma Knife radiosurgery in the 6-OHDA rodent model of hemi-parkinsonism.
Topics: Animals; Caudate Nucleus; Dominance, Cerebral; Glial Cell Line-Derived Neurotrophic Factor; Immunoen | 2002 |
Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Carbon Tetrachloride; Che | 2003 |
Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury.
Topics: Adrenergic alpha-Antagonists; Animals; Antioxidants; Body Weight; Diet; Fatty Liver; Hepatocytes; Li | 2003 |
Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine.
Topics: Animals; Apoptosis; Biomarkers; Catecholamines; Cell Differentiation; Cell Proliferation; Necrosis; | 2006 |
Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans.
Topics: Adrenergic Agents; Animals; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Ion | 2007 |
Subsequent biological effects of chemical sympathectomy in rats undergoing unilateral testicular torsion.
Topics: Animals; Atrophy; Female; Fertility; Male; Necrosis; Oxidopamine; Pregnancy; Random Allocation; Rats | 1995 |
Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells.
Topics: Animals; Apoptosis; Cell Survival; Coumarins; Culture Media, Serum-Free; Cysteine Endopeptidases; Cy | 1998 |
The toxicity of 6-hydroxydopamine on PC12 and P19 cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aurintricarboxylic Acid; Biological Transport; Bisbenzimi | 1999 |