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oxidopamine and Myopia

oxidopamine has been researched along with Myopia in 8 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
" If the eyes of young chickens are deprived of clear vision by translucent occluders, they develop considerable amounts of axial myopia within days."7.68Diurnal growth rhythms in the chicken eye: relation to myopia development and retinal dopamine levels. ( Schaeffel, F; Weiss, S, 1993)
"For reserpine (which was most extensively studied) electroretinograms were recorded to test retinal function [Fig."5.29Studies on the role of the retinal dopamine/melatonin system in experimental refractive errors in chickens. ( Bartmann, M; Hagel, G; Schaeffel, F; Zrenner, E, 1995)
"Because there is evidence that deprivation myopia is based on a local-retinal mechanism in the eye that probably remains functional after cycloplegia as well as after ciliary ganglion or Edinger-Westphal lesions, none of these treatments provides insight into whether accommodation tonus is also important in the control of axial eye growth."3.69Chick eyes under cycloplegia compensate for spectacle lenses despite six-hydroxy dopamine treatment. ( Schaeffel, F; Schwahn, HN, 1994)
" If the eyes of young chickens are deprived of clear vision by translucent occluders, they develop considerable amounts of axial myopia within days."3.68Diurnal growth rhythms in the chicken eye: relation to myopia development and retinal dopamine levels. ( Schaeffel, F; Weiss, S, 1993)
"For reserpine (which was most extensively studied) electroretinograms were recorded to test retinal function [Fig."1.29Studies on the role of the retinal dopamine/melatonin system in experimental refractive errors in chickens. ( Bartmann, M; Hagel, G; Schaeffel, F; Zrenner, E, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, XH1
Qian, KW1
Xu, GZ1
Li, YY1
Ma, YY1
Huang, F1
Wang, YQ1
Zhou, X1
Qu, J1
Yang, XL1
Zhong, YM1
Weng, SJ1
Schaeffel, F7
Bartmann, M2
Hagel, G2
Zrenner, E3
Schwahn, HN1
Kohler, K2
Weiss, S1
Hoffmann, M1
Li, X1
Konrad, K1
Eberhart, Z1
Li, XX1

Other Studies

8 other studies available for oxidopamine and Myopia

ArticleYear
The Role of Retinal Dopamine in C57BL/6 Mouse Refractive Development as Revealed by Intravitreal Administration of 6-Hydroxydopamine.
    Investigative ophthalmology & visual science, 2016, Oct-01, Volume: 57, Issue:13

    Topics: Adrenergic Agents; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models,

2016
Studies on the role of the retinal dopamine/melatonin system in experimental refractive errors in chickens.
    Vision research, 1995, Volume: 35, Issue:9

    Topics: 5,7-Dihydroxytryptamine; Animals; Chickens; Circadian Rhythm; Dopamine; Electroretinography; Male; M

1995
Chick eyes under cycloplegia compensate for spectacle lenses despite six-hydroxy dopamine treatment.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:9

    Topics: Accommodation, Ocular; Animals; Chickens; Ciliary Body; Eye; Injections; Light; Mydriatics; Myopia;

1994
6-Hydroxy dopamine does not affect lens-induced refractive errors but suppresses deprivation myopia.
    Vision research, 1994, Volume: 34, Issue:2

    Topics: Animals; Biometry; Chickens; Eye; Lenses; Myopia; Oxidopamine; Refraction, Ocular; Refractive Errors

1994
Diurnal growth rhythms in the chicken eye: relation to myopia development and retinal dopamine levels.
    Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1993, Volume: 172, Issue:3

    Topics: Animals; Chickens; Circadian Rhythm; Dopamine; Eye; Myopia; Oxidopamine; Refraction, Ocular; Retina;

1993
Melatonin and deprivation myopia in chickens.
    Neurochemistry international, 1996, Volume: 28, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Chickens; Circadian Rhythm; Electroretinography;

1996
A dose related response of 6-OHDA on chicken spectral sensitivity and oscillatory potentials of recording electroretinograms.
    Chinese medical journal, 1996, Volume: 109, Issue:10

    Topics: Adrenergic Agents; Animals; Chickens; Dose-Response Relationship, Drug; Electroretinography; Myopia;

1996
Dose-dependent effects of 6-hydroxy dopamine on deprivation myopia, electroretinograms, and dopaminergic amacrine cells in chickens.
    Visual neuroscience, 1992, Volume: 9, Issue:5

    Topics: Animals; Chickens; Electroretinography; Myopia; Neurons; Oxidopamine; Photoreceptor Cells; Receptors

1992