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oxidopamine and Myocardial Ischemia

oxidopamine has been researched along with Myocardial Ischemia in 3 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Yohimbine was antiarrhythmic in the presence and absence of platelets, suggesting direct myocardial effects, but BN 52021 had no antiarrhythmic effects."1.29Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects. ( Flores, NA; Goulielmos, NV; Seghatchian, MJ; Sheridan, DJ, 1994)
"Reserpine pretreatment did not affect the response to ischaemia or to preconditioning, although LDH release tended to be greater than in normal hearts, especially in the non-preconditioned group."1.29Endogenous catecholamines are not necessary for ischaemic preconditioning in the isolated perfused rat heart. ( Baird, AJ; Dzwonczyk, S; Grover, GJ; Murray, HN; Sleph, PG; Weselcouch, EO, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Béguin, PC1
El-Helou, V1
Gillis, MA1
Duquette, N1
Gosselin, H1
Brugada, R1
Villeneuve, L1
Lauzier, D1
Tanguay, JF1
Ribuot, C1
Calderone, A1
Flores, NA1
Goulielmos, NV1
Seghatchian, MJ1
Sheridan, DJ1
Weselcouch, EO1
Baird, AJ1
Sleph, PG1
Dzwonczyk, S1
Murray, HN1
Grover, GJ1

Other Studies

3 other studies available for oxidopamine and Myocardial Ischemia

ArticleYear
Nestin (+) stem cells independently contribute to neural remodelling of the ischemic heart.
    Journal of cellular physiology, 2011, Volume: 226, Issue:5

    Topics: Adrenergic Fibers; Adult Stem Cells; Animals; Cell Differentiation; Cell Lineage; Disease Models, An

2011
Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects.
    Cardiovascular research, 1994, Volume: 28, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Platelets; Colforsin; Diterpenes;

1994
Endogenous catecholamines are not necessary for ischaemic preconditioning in the isolated perfused rat heart.
    Cardiovascular research, 1995, Volume: 29, Issue:1

    Topics: Animals; Catecholamines; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Ischemia;

1995