Page last updated: 2024-11-02

oxidopamine and Myelopathy

oxidopamine has been researched along with Myelopathy in 3 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yadav, AP1
Fuentes, R1
Zhang, H1
Vinholo, T1
Wang, CH1
Freire, MA1
Nicolelis, MA1
Bervoets, K1
Millan, MJ1
Buchanan, JT1
Nornes, HO1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Thoracic Dorsal Spinal Cord Stimulation for the Treatment of Gait and Balance Impairments in Parkinson Disease[NCT03079310]15 participants (Anticipated)Interventional2016-02-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for oxidopamine and Myelopathy

ArticleYear
Chronic spinal cord electrical stimulation protects against 6-hydroxydopamine lesions.
    Scientific reports, 2014, Jan-23, Volume: 4

    Topics: Adrenergic Agents; Animals; Behavior, Animal; Chronic Disease; Deep Brain Stimulation; Disease Model

2014
5-HT1A receptors and the tail-flick response. V. Opposite modulation of 5-HT1A receptor-induced spontaneous tail-flicks by alpha 1A- as compared with alpha 2D-adrenoceptors in rat lumbar spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenerg

1994
Transplants of embryonic brainstem containing the locus coeruleus into spinal cord enhance the hindlimb flexion reflex in adult rats.
    Brain research, 1986, Sep-03, Volume: 381, Issue:2

    Topics: Animals; Catecholamines; Female; Hindlimb; Hydroxydopamines; Locus Coeruleus; Oxidopamine; Rats; Rat

1986