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oxidopamine and Morphine Abuse

oxidopamine has been researched along with Morphine Abuse in 4 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
"Morphine withdrawal was induced by intravenous (i."1.30Interruption of central noradrenergic pathways and morphine withdrawal excitation of oxytocin neurones in the rat. ( Brown, CH; Bull, PM; Leng, G; Ludwig, M; Munro, G; Murphy, NP; Russell, JA, 1998)
"Morphine dependence was induced by s."1.30Total neurochemical lesion of noradrenergic neurons of the locus ceruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal. ( Cador, M; Caillé, S; Espejo, EF; Koob, GF; Reneric, JP; Stinus, L, 1999)
"Cimetidine was without effect on wet-dog shakes, burrowing, and body weight loss."1.29The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice. ( el Kadi, AO; Sharif, SI, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
el Kadi, AO1
Sharif, SI1
Brown, CH1
Murphy, NP1
Munro, G1
Ludwig, M1
Bull, PM1
Leng, G1
Russell, JA1
Caillé, S1
Espejo, EF1
Reneric, JP1
Cador, M1
Koob, GF1
Stinus, L1
Aston-Jones, G1
Delfs, JM1
Druhan, J1
Zhu, Y1

Other Studies

4 other studies available for oxidopamine and Morphine Abuse

ArticleYear
The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine

1996
Interruption of central noradrenergic pathways and morphine withdrawal excitation of oxytocin neurones in the rat.
    The Journal of physiology, 1998, Mar-15, Volume: 507 ( Pt 3)

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Cerebral Ventricles; Cholecystokinin; E

1998
Total neurochemical lesion of noradrenergic neurons of the locus ceruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Avoidance Learning; Brain; Clonidine; Dopamine; Locus Coeruleus;

1999
The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal.
    Annals of the New York Academy of Sciences, 1999, Jun-29, Volume: 877

    Topics: Amygdala; Animals; Axonal Transport; Caudate Nucleus; Male; Microinjections; Morphine Dependence; Na

1999