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oxidopamine and Hypothermia, Accidental

oxidopamine has been researched along with Hypothermia, Accidental in 9 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Research Excerpts

ExcerptRelevanceReference
") with 6-hydroxydopamine (6OHDA) (50 micrograms per mouse), as soon as the hypothermia elicited by the neurotoxin had vanished (3 hr), the hypothermic effect induced by the direct D2 dopamine receptor agonist RU 24926 (1 mg/kg, s."3.69Rapid and long lasting reduction of the hypothermic effect of a D2 dopamine agonist after an intracerebroventricular injection of 6-hydroxydopamine. ( Costentin, J; Dourmap, N; Suaudeau, C, 1995)
" On the contrary, the hypothermia is partly antagonized by norepinephrine uptake inhibitors (desipramine, nomifensine, viloxazine, maprotiline, protryptiline), as well as amfonelic acid."3.67Involvement of norepinephrine neurons in the hypothermia induced by intracerebroventricular administration of 6-hydroxydopamine in mice, evidenced by antidepressants. ( Costentin, J; Leroux-Nicollet, I; Panissaud, C, 1988)
" To verify this hypothesis, we investigated the influence of hypothermia on the toxic activity of both neurotoxins."1.32Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons. ( Cleren, C; Costentin, J; Naudin, B, 2003)
"Cimetidine was without effect on wet-dog shakes, burrowing, and body weight loss."1.29The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice. ( el Kadi, AO; Sharif, SI, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marcangione, C1
Constantin, A1
Clarke, PB1
Cleren, C1
Naudin, B1
Costentin, J4
Amar, A1
Sanyal, AK2
Beotra, A1
Suaudeau, C2
Dourmap, N2
el Kadi, AO1
Sharif, SI2
Drouet, I1
el-Kadi, AO1
Leroux-Nicollet, I1
Panissaud, C1

Other Studies

9 other studies available for oxidopamine and Hypothermia, Accidental

ArticleYear
Lack of effect of dopaminergic denervation on caudate-putamen hyperthermia or hypothermia induced by drugs and mild stressors.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:1

    Topics: Animals; Caudate Nucleus; Dopamine; Dopamine Antagonists; Fever; Hypothermia; Male; Oxidopamine; Put

2010
Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
    Brain research, 2003, Nov-07, Volume: 989, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Binding Si

2003
Immobilization stress in rats: effect on rectal temperature and possible role of brain monoamines in hypothermia.
    Psychopharmacology, 1981, Volume: 73, Issue:2

    Topics: 5,6-Dihydroxytryptamine; Adrenalectomy; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Fenclon

1981
Immobilization stress induced hyperthermia in rats: possible role of noradrenaline.
    Indian journal of experimental biology, 1982, Volume: 20, Issue:10

    Topics: Animals; Benztropine; Hydroxydopamines; Hypothermia; Male; Norepinephrine; Oxidopamine; Rats; Rats,

1982
Rapid and long lasting reduction of the hypothermic effect of a D2 dopamine agonist after an intracerebroventricular injection of 6-hydroxydopamine.
    Neuropharmacology, 1995, Volume: 34, Issue:1

    Topics: Animals; Desipramine; Dose-Response Relationship, Drug; Hypothermia; Injections, Spinal; Male; Mice;

1995
The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine

1996
Mechanism of the hypothermic effect of MPP+ administered centrally in mice.
    Neuropharmacology, 1997, Volume: 36, Issue:7

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Body Temperature; Dopamine Agents; Dose-Response Relationship,

1997
The role of dopamine in the expression of morphine withdrawal.
    General pharmacology, 1998, Volume: 30, Issue:4

    Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopami

1998
Involvement of norepinephrine neurons in the hypothermia induced by intracerebroventricular administration of 6-hydroxydopamine in mice, evidenced by antidepressants.
    Journal of neural transmission, 1988, Volume: 74, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Desipramine; Dose-Response Relationship, Drug; Hydroxydopamin

1988