oxidopamine has been researched along with Hypersensitivity in 1 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although pain is a prevalent nonmotor symptom in Parkinson's disease (PD), it is undertreated, in part because of our limited understanding of the underlying mechanisms." | 1.56 | Reversal of hyperactive subthalamic circuits differentially mitigates pain hypersensitivity phenotypes in parkinsonian mice. ( Cao, JL; Gu, W; Luan, Y; Tang, D; Wu, H; Wu, Y; Xiao, C; Zhou, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luan, Y | 1 |
| Tang, D | 1 |
| Wu, H | 1 |
| Gu, W | 1 |
| Wu, Y | 1 |
| Cao, JL | 1 |
| Xiao, C | 1 |
| Zhou, C | 1 |
1 other study available for oxidopamine and Hypersensitivity
| Article | Year |
|---|---|
Reversal of hyperactive subthalamic circuits differentially mitigates pain hypersensitivity phenotypes in parkinsonian mice.
Topics: Animals; Basal Ganglia; Disease Models, Animal; Dopamine Antagonists; Globus Pallidus; Humans; Hyper | 2020 |