oxidopamine has been researched along with Gastroparesis in 5 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Gastroparesis: Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with Parkinson's disease (PD) often suffer from delayed gastric emptying, but the underlying mechanism remains unclear." | 1.72 | Impaired nitrergic relaxation in pyloric sphincter of the 6-OHDA Parkinson's disease rat. ( Fan, RF; Fan, YY; Wang, T; Yu, X; Zhang, Y; Zheng, LF; Zhu, JX, 2022) |
| "Gastroparesis is a common non-motor system symptom of Parkinson's disease (PD)." | 1.40 | The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6-hydroxydopamine microinjection in the substantia nigra. ( Chen, CL; Fan, RF; Feng, XY; Li, LS; Ren, QZ; Song, J; Zhang, XL; Zhang, Y; Zheng, LF; Zhu, JX, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, YY | 1 |
| Zhang, Y | 3 |
| Fan, RF | 2 |
| Wang, T | 1 |
| Yu, X | 1 |
| Zheng, LF | 2 |
| Zhu, JX | 2 |
| Song, J | 2 |
| Chen, CL | 1 |
| Ren, QZ | 1 |
| Zhang, XL | 1 |
| Feng, XY | 1 |
| Li, LS | 1 |
| Zheng, L | 1 |
| Zhang, X | 1 |
| Feng, X | 1 |
| Fan, R | 1 |
| Sun, L | 1 |
| Hong, F | 1 |
| Zhu, J | 1 |
| Toti, L | 1 |
| Travagli, RA | 1 |
| Pellegrini, C | 1 |
| Antonioli, L | 1 |
| Colucci, R | 1 |
| Ballabeni, V | 1 |
| Barocelli, E | 1 |
| Bernardini, N | 1 |
| Blandizzi, C | 1 |
| Fornai, M | 1 |
1 review available for oxidopamine and Gastroparesis
| Article | Year |
|---|---|
Gastric motor dysfunctions in Parkinson's disease: Current pre-clinical evidence.
Topics: alpha-Synuclein; Animals; Cholecystokinin; Efferent Pathways; Enteric Nervous System; Gastric Emptyi | 2015 |
4 other studies available for oxidopamine and Gastroparesis
| Article | Year |
|---|---|
Impaired nitrergic relaxation in pyloric sphincter of the 6-OHDA Parkinson's disease rat.
Topics: Animals; Gastroparesis; Humans; Nitric Oxide Synthase Type I; Oxidopamine; Parkinson Disease; Pyloru | 2022 |
The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6-hydroxydopamine microinjection in the substantia nigra.
Topics: Acetylcholine; Animals; Blotting, Western; Disease Models, Animal; Dopamine; Fluorescent Antibody Te | 2014 |
Upregulation of β1-adrenoceptors is involved in the formation of gastric dysmotility in the 6-hydroxydopamine rat model of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Emptying; Gastroparesis; | 2014 |
Gastric dysregulation induced by microinjection of 6-OHDA in the substantia nigra pars compacta of rats is determined by alterations in the brain-gut axis.
Topics: Animals; Biomarkers; Choline O-Acetyltransferase; Disease Models, Animal; Dopamine Antagonists; Dopa | 2014 |