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oxidopamine and Fatigue Syndrome, Chronic

oxidopamine has been researched along with Fatigue Syndrome, Chronic in 1 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Research Excerpts

ExcerptRelevanceReference
"Chronic fatigue is a complex and little understood symptom for which there is no safe and effective pharmacotherapy."5.33Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity. ( Brown-Borg, HM; Dhanasekaran, M; Manyam, BV; Tharakan, B, 2006)
"Chronic fatigue is a complex and little understood symptom for which there is no safe and effective pharmacotherapy."1.33Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity. ( Brown-Borg, HM; Dhanasekaran, M; Manyam, BV; Tharakan, B, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tharakan, B1
Dhanasekaran, M1
Brown-Borg, HM1
Manyam, BV1

Other Studies

1 other study available for oxidopamine and Fatigue Syndrome, Chronic

ArticleYear
Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:3

    Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Chronic Disease; Dioscoreaceae; Fatigu

2006