oxidopamine has been researched along with Drug Withdrawal Symptoms in 15 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine withdrawal was induced by intravenous (i." | 1.30 | Interruption of central noradrenergic pathways and morphine withdrawal excitation of oxytocin neurones in the rat. ( Brown, CH; Bull, PM; Leng, G; Ludwig, M; Munro, G; Murphy, NP; Russell, JA, 1998) |
| "Morphine dependence was induced by s." | 1.30 | Total neurochemical lesion of noradrenergic neurons of the locus ceruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal. ( Cador, M; Caillé, S; Espejo, EF; Koob, GF; Reneric, JP; Stinus, L, 1999) |
| "Cimetidine was without effect on wet-dog shakes, burrowing, and body weight loss." | 1.29 | The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice. ( el Kadi, AO; Sharif, SI, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 10 (66.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, M | 1 |
| Ba, M | 1 |
| Song, L | 1 |
| Liu, Z | 1 |
| Oh, JD | 1 |
| Chartisathian, K | 1 |
| Ahmed, SM | 1 |
| Chase, TN | 1 |
| Broadley, KJ | 1 |
| Williams, RG | 1 |
| Hawthorn, MH | 1 |
| Grassby, PF | 1 |
| Feigenbaum, JJ | 1 |
| Yanai, J | 1 |
| el-Kadi, AO | 2 |
| Sharif, SI | 3 |
| el Kadi, AO | 1 |
| Ehsan, E | 1 |
| Akerman, KE | 1 |
| Brown, CH | 1 |
| Murphy, NP | 1 |
| Munro, G | 1 |
| Ludwig, M | 1 |
| Bull, PM | 1 |
| Leng, G | 1 |
| Russell, JA | 1 |
| Caillé, S | 1 |
| Espejo, EF | 1 |
| Reneric, JP | 1 |
| Cador, M | 1 |
| Koob, GF | 1 |
| Stinus, L | 1 |
| Aston-Jones, G | 1 |
| Delfs, JM | 1 |
| Druhan, J | 1 |
| Zhu, Y | 1 |
| Bhat, RV | 1 |
| Worley, PF | 1 |
| Cole, AJ | 1 |
| Baraban, JM | 1 |
| Hall, NR | 1 |
| O'Grady, MP | 1 |
| Menzies, RA | 1 |
| Carey, RJ | 1 |
| Jenner, P | 1 |
| Boyce, S | 1 |
| Marsden, CD | 1 |
4 reviews available for oxidopamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Mechanisms of cardiac supersensitivity to sympathomimetic amines.
Topics: Animals; Guinea Pigs; Heart; Humans; Hydroxydopamines; Isoproterenol; Metaproterenol; Oxidopamine; R | 1984 |
Evidence for the involvement of central dopaminergic receptors in the acute and chronic effects induced by barbiturates.
Topics: Adenylyl Cyclases; Animals; Barbiturates; Brain; Chlorpromazine; Dopamine; Drug Interactions; Drug T | 1983 |
Neuroimmunopharmacologic effects of drugs of abuse.
Topics: Animals; Autonomic Nervous System; Brain Chemistry; Catecholamines; Complement System Proteins; Huma | 1991 |
Receptor changes during chronic dopaminergic stimulation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain Diseases; Bromocripti | 1988 |
11 other studies available for oxidopamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Comparative effects of acute or chronic administration of levodopa to 6-OHDA-lesioned rats on the expression and phosphorylation of N-methyl-D-aspartate receptor NR1 subunits in the striatum.
Topics: Animals; Blotting, Western; Dopamine Agents; Female; Indicators and Reagents; Levodopa; Movement; Ne | 2009 |
Cyclic AMP responsive element binding protein phosphorylation and persistent expression of levodopa-induced response alterations in unilateral nigrostriatal 6-OHDA lesioned rats.
Topics: Animals; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; L | 2003 |
The role of 5-HT in the expression of morphine withdrawal in mice.
Topics: Animals; Cyproheptadine; Male; Methysergide; Mice; Morphine; Naloxone; Oxidopamine; Serotonin; Subst | 1995 |
The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.
Topics: Animals; Behavior, Animal; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine | 1996 |
Effect of morphine on rotational behavior of unilaterally brain-lesioned mice and rats: morphine withdrawal and development of tolerance.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Drug Tolerance; Functiona | 1997 |
Interruption of central noradrenergic pathways and morphine withdrawal excitation of oxytocin neurones in the rat.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Cerebral Ventricles; Cholecystokinin; E | 1998 |
The role of dopamine in the expression of morphine withdrawal.
Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopami | 1998 |
Total neurochemical lesion of noradrenergic neurons of the locus ceruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal.
Topics: Adrenergic alpha-Agonists; Animals; Avoidance Learning; Brain; Clonidine; Dopamine; Locus Coeruleus; | 1999 |
The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal.
Topics: Amygdala; Animals; Axonal Transport; Caudate Nucleus; Male; Microinjections; Morphine Dependence; Na | 1999 |
Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268.
Topics: Animals; Apomorphine; Benzazepines; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Ea | 1992 |
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug | 1991 |