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oxidopamine and Diabetes Insipidus

oxidopamine has been researched along with Diabetes Insipidus in 4 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Diabetes Insipidus: A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.

Research Excerpts

ExcerptRelevanceReference
" The cardiovascular effects of bolus intravenous injections of vasopressin, angiotensin II and noradrenaline were studied in 6-hydroxydopamine pretreated, anaesthetized Brattleboro rats with hereditary diabetes insipidus and normal rats of the parent Long Evans strain."3.67Cardiovascular interactions between vasopressin, angiotensin and noradrenaline in the Brattleboro rat. ( Laycock, JF; Lightman, SL, 1989)
"We suggest that A1 hypertension is predominantly mediated through increased activity of sympathetic vasoconstrictor nerves, and that circulating adrenaline and vasopressin only make a minor contribution to the increase in pressure."1.27Hypertension after brainstem (A1) lesions in normal rats and in rats with adrenalectomy, sympathectomy or diabetes insipidus. ( Cain, M; Chalmers, J; Kapoor, V; Minson, J, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morgan, ML1
Anderson, RJ1
Ellis, MA1
Berl, T1
Livingston, A1
Oner, G1
Lederis, K1
Chalmers, J1
Minson, J1
Kapoor, V1
Cain, M1
Laycock, JF1
Lightman, SL1

Other Studies

4 other studies available for oxidopamine and Diabetes Insipidus

ArticleYear
Mechanism of cold diuresis in the rat.
    The American journal of physiology, 1983, Volume: 244, Issue:2

    Topics: Animals; Arginine Vasopressin; Cardiac Output; Cold Temperature; Diabetes Insipidus; Diuresis; Hydro

1983
Reversal of 6-hydroxydopamine-induced hypotension in Long Evans and diabetes insipidus (Brattleboro) rats.
    Pharmacology, 1983, Volume: 26, Issue:4

    Topics: Animals; Arginine Vasopressin; Blood Pressure; Diabetes Insipidus; Heart Rate; Hematocrit; Hydroxydo

1983
Hypertension after brainstem (A1) lesions in normal rats and in rats with adrenalectomy, sympathectomy or diabetes insipidus.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Arginine Vasopressin; Brain Stem; Diabetes Insipidus; Epinep

1984
Cardiovascular interactions between vasopressin, angiotensin and noradrenaline in the Brattleboro rat.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Angiotensin II; Animals; Diabetes Insipidus; Hemodynamics; Hydroxydopamines; Male; Norepinephrine; O

1989