oxidopamine has been researched along with Depressive Disorder in 12 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following depletion of brain DA, but not NE, animals exhibited a "supersensitive" increase in plasma ACTH values, which was evidenced by a sixfold left shift in the dose-response properties of PHY." | 1.27 | Supersensitive endocrine response to physostigmine in dopamine-depleted rats: a model of depression? ( Britton, KT; Downs, NS; Gibbs, DM; Koob, GF; Swerdlow, NR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Mendes-Pinheiro, B | 1 |
| Soares-Cunha, C | 1 |
| Marote, A | 1 |
| Loureiro-Campos, E | 1 |
| Campos, J | 1 |
| Barata-Antunes, S | 1 |
| Monteiro-Fernandes, D | 1 |
| Santos, D | 1 |
| Duarte-Silva, S | 1 |
| Pinto, L | 1 |
| José Salgado, A | 1 |
| Kamińska, K | 1 |
| Lenda, T | 1 |
| Konieczny, J | 1 |
| Czarnecka, A | 1 |
| Lorenc-Koci, E | 1 |
| Hemmerle, AM | 1 |
| Dickerson, JW | 1 |
| Herman, JP | 1 |
| Seroogy, KB | 1 |
| Luo, XF | 1 |
| Zhang, BL | 1 |
| Li, JC | 1 |
| Yang, YY | 1 |
| Sun, YF | 1 |
| Zhao, H | 1 |
| Liu, KC | 1 |
| Li, JY | 1 |
| Tan, HH | 2 |
| Du, CX | 2 |
| Xie, W | 1 |
| Zhang, YM | 1 |
| Ma, WL | 1 |
| Zhang, L | 2 |
| Santiago, RM | 1 |
| Tonin, FS | 1 |
| Barbiero, J | 1 |
| Zaminelli, T | 1 |
| Boschen, SL | 1 |
| Andreatini, R | 1 |
| Da Cunha, C | 1 |
| Lima, MM | 1 |
| Vital, MA | 1 |
| Lee, M | 1 |
| Ryu, YH | 1 |
| Cho, WG | 1 |
| Kang, YW | 1 |
| Lee, SJ | 1 |
| Jeon, TJ | 1 |
| Lyoo, CH | 1 |
| Kim, CH | 1 |
| Kim, DG | 1 |
| Lee, K | 1 |
| Choi, TH | 1 |
| Choi, JY | 1 |
| Furlanetti, LL | 1 |
| Coenen, VA | 1 |
| Aranda, IA | 1 |
| Döbrössy, MD | 1 |
| Faggiani, E | 1 |
| Delaville, C | 1 |
| Benazzouz, A | 1 |
| Zhang, QJ | 1 |
| Li, LB | 1 |
| Zhang, J | 1 |
| Niu, XL | 1 |
| Liu, J | 1 |
| Ventura, R | 1 |
| Cabib, S | 1 |
| Puglisi-Allegra, S | 1 |
| Downs, NS | 1 |
| Britton, KT | 1 |
| Gibbs, DM | 1 |
| Koob, GF | 1 |
| Swerdlow, NR | 1 |
12 other studies available for oxidopamine and Depressive Disorder
| Article | Year |
|---|---|
Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response.
Topics: Animals; Anxiety; Behavior, Animal; Corpus Striatum; Depressive Disorder; Disease Models, Animal; Fe | 2021 |
Depressive-like neurochemical and behavioral markers of Parkinson's disease after 6-OHDA administered unilaterally to the rat medial forebrain bundle.
Topics: Animals; Behavior, Animal; Depressive Disorder; Dopamine; Male; Medial Forebrain Bundle; Norepinephr | 2017 |
Stress exacerbates experimental Parkinson's disease.
Topics: Animals; Antigens, Nuclear; Cell Count; Cell Survival; Chronic Disease; Depressive Disorder; Dopamin | 2014 |
Lateral habenula as a link between dopaminergic and serotonergic systems contributes to depressive symptoms in Parkinson's disease.
Topics: Animals; Ascorbic Acid; Depressive Disorder; Dopamine; Electric Stimulation; Electron Transport Comp | 2015 |
Serotonin₆ receptors in the dorsal hippocampus regulate depressive-like behaviors in unilateral 6-hydroxydopamine-lesioned Parkinson's rats.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Dopamine; Excitatory Amino Acid Transporter 3; | 2015 |
The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease.
Topics: Anhedonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Depressive Disor | 2015 |
Relationship between dopamine deficit and the expression of depressive behavior resulted from alteration of serotonin system.
Topics: Animals; Brain; Depressive Disorder; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Tran | 2015 |
Chronic deep brain stimulation of the medial forebrain bundle reverses depressive-like behavior in a hemiparkinsonian rodent model.
Topics: Adrenergic Agents; Amphetamine; Animals; Central Nervous System Stimulants; Deep Brain Stimulation; | 2015 |
The combined depletion of monoamines alters the effectiveness of subthalamic deep brain stimulation.
Topics: Animals; Anxiety Disorders; Benzylamines; Biogenic Monoamines; Catalepsy; Corpus Striatum; Deep Brai | 2015 |
Activation and blockade of serotonin7 receptors in the prelimbic cortex regulate depressive-like behaviors in a 6-hydroxydopamine-induced Parkinson's disease rat model.
Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Dietary Sucrose; Dopamine; Dose-Response | 2015 |
Genetic susceptibility of mesocortical dopamine to stress determines liability to inhibition of mesoaccumbens dopamine and to behavioral 'despair' in a mouse model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depressive Disorder; Dise | 2002 |
Supersensitive endocrine response to physostigmine in dopamine-depleted rats: a model of depression?
Topics: Adrenocorticotropic Hormone; Animals; Brain Chemistry; Depressive Disorder; Disease Models, Animal; | 1986 |