Page last updated: 2024-11-02

oxidopamine and Depressive Disorder, Major

oxidopamine has been researched along with Depressive Disorder, Major in 1 studies

Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Tuon, T1
Meirelles, SS1
de Moura, AB1
Rosa, T1
Borba, LA1
Botelho, MEM1
Abelaira, HM1
de Mathia, GB1
Danielski, LG1
Fileti, ME1
Petronilho, F1
Ignácio, ZM1
Quevedo, J1
Réus, GZ1

Other Studies

1 other study available for oxidopamine and Depressive Disorder, Major

ArticleYear
Behavior and oxidative stress parameters in rats subjected to the animal's models induced by chronic mild stress and 6-hydroxydopamine.
    Behavioural brain research, 2021, 05-21, Volume: 406

    Topics: Adrenergic Agents; Animals; Behavior, Animal; Brain; Corpus Striatum; Depressive Disorder, Major; Di

2021